Effects of hyperbaric oxygen on vascular endothelial function in patients with slow coronary flow

   Background: To improve therapy for slow coronary flow (SCF), the effects of hyperbaric oxygen (HBO) therapy on vascular endothelial function in SCF patients is the focus of this investigation. Methods: Ninety-eight patients who exhibited chest discomfort were retrospectively analyzed, and di­agnosed with SCF by coronary artery angiography at the Third Hospital of Hebei Medical University, Shijiazhuang, China from 2014 to 2016. The patients were divided into two groups according to the following treatment: HBO group (n = 48) and the control group (n = 50). Patients in the control group were administrated with conventional treatment, while those in the HBO group were administrated HBO therapy for 4 weeks in addition to conventional treatment. To evaluate the effects of HBO on vas­cular endothelial functions, plasma levels of nitric oxide (NO), calcitonin gene-related peptide (CGRP), endothelin-1 (ET-1), high sensitivity C-reactive protein (hsCRP) as well as endothelial-dependent flow-mediated vasodilation (FMD) of the brachial artery were measured in both groups before and after their respective treatments. Results: There were no significant differences in plasma levels of NO, ET-1, CGRP, hsCRP nor in FMD measurements between the two groups before treatment (p > 0.05). Moreover, the levels of all the parameters measured showed no significant changes before and after treatment in the control group. However, when comparing the control group, FMD and plasma NO and CGRP levels were significantly increased in the HBO group after treatment (p < 0.01), whereas hsCRP and ET-1 levels decreased dramatically (p < 0.001). Conclusions: The HBO treatment in addition to conventional therapy may significantly improve the vascular endothelial function in SCF patients. (Cardiol J 2018; 25, 1: 106–112

The Material Chosen Methods Base on AUTODYN Dynamic for Substrate Film of Flexible Film Sensor Circuit

In the process of ammunition test & evaluation, to accurately evaluate the lethality of personnel targets on the battlefield, it is necessary to accurately measure the velocity and coordinates of ammunition fragments. At present, the most effective method for measuring the projectile velocity and the midpoint coordinates of ammunition is to use the measuring circuit printed with silver paste on the flexible substrate material. Considering that the physical properties of the substrate material will greatly affect the velocity attenuation value of the fragments and the size of the hole at the hitting position, this article mainly uses the AUTODYN software to simulate the process of the projectile penetrating three kinds of polymer materials and copper circuit which are used in many universities and test ground and selects the suitable polymer material that has the least negative effects on the velocity of the projectile, The speed measurement accuracy of the flexible silver paste printing film sensors circuit printed on three different polymer substrate materials is compared by the live-fire test method, which verifies the effectiveness of the simulation calculation process and proves that the polycarbonate (PC) material is the most suitable substrate material for the silver paste printed circuit among the Polyimide (PI), Polycarbonate (PC), and Polyethylene terephthalate (PET) polymer materials which are the most common and cheapest one in market