The infall of the Virgo elliptical galaxy M60 toward M87 and the gaseous structures produced by Kelvin-Helmholtz instabilities

We present Chandra observations of hot gas structures, characteristic of gas stripping during infall, in the Virgo cluster elliptical galaxy M60 (NGC4649) located 1 Mpc east of M87. 0.5−2 keV Chandra X-ray images show a sharp leading edge in the surface brightness 12.4±0.1 kpc north and west of the galaxy center in the direction of M87 characteristic of a merger cold front due to M60's motion through the Virgo ICM. We measured a temperature of 1.00±0.02 keV for abundance 0.5Z⊙ inside the edge and 1.37+0.35−0.19 keV for abundance 0.1Z⊙ in the Virgo ICM free stream region. We find that the observed jump in surface brightness yields a density ratio of 6.44+1.04−0.67 between gas inside the edge and in the cluster free stream region. If the edge is a cold front due solely to the infall of M60 in the direction of M87, we find a pressure ratio of 4.7+1.7−1.4 and Mach number 1.7±0.3. For 1.37 keV Virgo gas we find a total infall velocity for M60 of 1030±180 kms−1. We calculate the motion in the plane of the sky to be 1012+183−192 km−1 implying an inclination angle ξ=11±3 degrees. Surface brightness profiles show the presence of a faint diffuse gaseous tail. We identify filamentary, gaseous wing structures caused by the galaxy's motion through the ICM. The structure and dimensions of these wings are consistent with simulations of Kelvin-Helmholtz instabilities as expected if the gas stripping is close to inviscid

Morphological aspects of male and female hands

This is an electronic version of an article published in Annals of Human Biology, 1996, 23(6), 491-494. Annals of Human Biology is available online at informaworldTM http://www.informaworld.com/smpp/content~content=a739339013~db=all~order=pageThis journal article discusses a series of hand radiographs from Gwynedd, North Wales, which were assessed for frequencies in digital and metacarpal formulae between the genders

Comparative Morphology of the Penis and Clitoris in Four Species of Moles (Talpidae).

The penile and clitoral anatomy of four species of Talpid moles (broad-footed, star-nosed, hairy-tailed, and Japanese shrew moles) were investigated to define penile and clitoral anatomy and to examine the relationship of the clitoral anatomy with the presence or absence of ovotestes. The ovotestis contains ovarian tissue and glandular tissue resembling fetal testicular tissue and can produce androgens. The ovotestis is present in star-nosed and hairy-tailed moles, but not in broad-footed and Japanese shrew moles. Using histology, three-dimensional reconstruction, and morphometric analysis, sexual dimorphism was examined with regard to a nine feature masculine trait score that included perineal appendage length (prepuce), anogenital distance, and presence/absence of bone. The presence/absence of ovotestes was discordant in all four mole species for sex differentiation features. For many sex differentiation features, discordance with ovotestes was observed in at least one mole species. The degree of concordance with ovotestes was highest for hairy-tailed moles and lowest for broad-footed moles. In relationship to phylogenetic clade, sex differentiation features also did not correlate with the similarity/divergence of the features and presence/absence of ovotestes. Hairy-tailed and Japanese shrew moles reside in separated clades, but they exhibit a high degree of congruence. Broad-footed and hairy-tailed moles reside within the same clade but had one of the lowest correlations in features and presence/absence of ovotestes. Thus, phylogenetic affinity and the presence/absence of ovotestes are poor predictors for most sex differentiation features within mole external genitalia

Improving GHB withdrawal with baclofen: study protocol for a feasibility study for a randomised controlled trial

Background: GHB (gamma-hydroxybutyrate) and its pro-drugs GBL (gamma-butyrolactone) and 1,4-butanediol (1,4-BD) are central nervous system depressants whose street names include ‘G’ and ‘liquid ecstasy’. They are used recreationally predominately for their stimulant and pro-sexual effects or for sedation to help with sleep and/or to ‘come down’ after using stimulant recreational drugs. Although overall population prevalence is low (0.1 %), in some groups such as men who have sex with men, GHB/GBL use may reach 20 %. GHB/GBL dependence may be associated with severe withdrawal with individuals presenting either acutely to emergency departments or to addiction services for support. Benzodiazepines are currently prescribed for GHB/GBL detoxification but do not prevent all complications, such as behavioural disinhibition, that may require hospitalisation or admission to a high dependency /intensive care unit. The GABAB receptor mediates most effects of GHB/GBL and the GABAB agonist, baclofen, has shown promise as an adjunct to benzodiazepines in reducing withdrawal severity when prescribed both during withdrawal and as a 2-day ‘preload’ prior to detoxification. The key aim of this feasibility study is provide information about recruitment and characteristics of the proposed outcome measure (symptom severity, complications including delirium and treatment escalation) to inform an application for a definitive randomised placebo controlled trial to determine the role of baclofen in the management of GHB/GBL withdrawal and whether starting baclofen 2 days earlier improves outcomes further. Methods/design: This is a prospective, randomised, double-blind, placebo-controlled feasibility study that will recruit participants (aged over 18 years) who are GHB/GBL- dependent and wish to undergo planned GHB/GBL detoxification or are at risk of acute withdrawal and are inpatients requiring unplanned withdrawal. We aim to recruit 88 participants: 28 unplanned inpatients and 60 planned outpatients. During detoxification we will compare baclofen 10 mg three times a day with placebo as an adjunct to the usual benzodiazepine regimen. In the planned outpatient arm, we will also compare a 2-day preload of baclofen 10 mg three times a day with placebo. Ratings of GHB/GBL withdrawal, sleep, depression, anxiety as well as GHB/GBL use will be collected. The main data analyses will be descriptive about recruitment and characterising the impact of adding baclofen to the usual benzodiazepine regimen on measures and outcomes of GHB/GBL withdrawal to provide estimates of variability and effect size. A qualitative approach will evaluate research participant and clinician acceptability and data collected to inform cost-effectiveness. Discussion: This feasibility study will inform a randomised controlled trial to establish whether adding baclofen to a benzodiazepine regimen reduces the severity and complications of GHB/GBL withdrawal

The perseverance of Pacioli's goods inventory accounting system

This paper details sources of the 'undoubtedly strange' (Yamey, 1994a, p.119) system of goods inventory records described in Pacioli’s 1494 bookkeeping treatise and traces the longevity and widespread use of this early perpetual inventory recording (EPIR) system in English language texts. By doing so and contrasting this system with the bookkeeping treatment of modern texts, it is shown that the EPIR system persisted as the dominant form of goods inventory accounting for between 400 and 500 years and that the reasons for its demise are worthy of further consideration and research

Near-IR variability properties of a selected sample of AGB stars

We present the results of a near-infrared monitoring programme of a selected sample of stars, initially suspected to be Mira variables and OH/IR stars, covering more than a decade of observations. The objects monitored cover the typical range of IRAS colours shown by O-rich stars on the Asymptotic Giant Branch and show a surprisingly large diversity of variability properties. 16 objects are confirmed as large-amplitude variables. Periods between 360 and 1800 days and typical amplitudes from 1 to 2 magnitudes could be determined for nine of them. In three light curves we find a systematic decrease of the mean brightness, two light curves show pronounced asymmetry. One source, IRAS 07222-2005, shows infrared colours typical of Mira variables but pulsates with a much longer period (approx. 1200 days) than a normal Mira. Two objects are ither close to (IRAS 03293+6010) or probably in (IRAS 18299-1705) the post-AGB phase. In IRAS 16029-3041 we found a systematic increase of the H-K colour of approximately 1 magnitude, which we interpret as evidence of a recent episode of enhanced mass loss. IRAS 18576+0341, a heavily obscured Luminous Blue Variable was also monitored. The star showed a continued decrease of brightness over a period of 7 years (1995 - 2002).Comment: 9 pages + 3 appendix, 36 figures, photometry table, accepted in Astronomy & Astrophysic

The ALMA detection of CO rotational line emission in AGB stars in the Large Magellanic Cloud

Context. Low- and intermediate-mass stars lose most of their stellar mass at the end of their lives on the asymptotic giant branch (AGB). Determining gas and dust mass-loss rates (MLRs) is important in quantifying the contribution of evolved stars to the enrichment of the interstellar medium. Aims: This study attempts to spectrally resolve CO thermal line emission in a small sample of AGB stars in the Large Magellanic Cloud (LMC). Methods: The Atacama Large Millimeter Array was used to observe two OH/IR stars and four carbon stars in the LMC in the CO J = 2-1 line. Results: We present the first measurement of expansion velocities in extragalactic carbon stars. All four C stars are detected and wind expansion velocities and stellar velocities are directly measured. Mass-loss rates are derived from modelling the spectral energy distribution and Spitzer/IRS spectrum with the DUSTY code. The derived gas-to-dust ratios allow the predicted velocities to agree with the observed gas-to-dust ratios. The expansion velocities and MLRs are compared to a Galactic sample of well-studied relatively low MLRs stars supplemented with extreme C stars with properties that are more similar to the LMC targets. Gas MLRs derived from a simple formula are significantly smaller than those derived from dust modelling, indicating an order of magnitude underestimate of the estimated CO abundance, time-variable mass loss, or that the CO intensities in LMC stars are lower than predicted by the formula derived for Galactic objects. This could be related to a stronger interstellar radiation field in the LMC. Conclusions: Although the LMC sample is small and the comparison to Galactic stars is non-trivial because of uncertainties in their distances (hence luminosities), it appears that for C stars the wind expansion velocities in the LMC are lower than in the solar neighbourhood, while the MLRs appear to be similar. This is in agreement with dynamical dust-driven wind models

Terrestrial hydrological controls on land surface phenology of African savannas and woodlands

This paper presents a continental-scale phenological analysis of African savannas and woodlands. We apply an array of synergistic vegetation and hydrological data records from satellite remote sensing and model simulations to explore the influence of rainy season timing and duration on regional land surface phenology and ecosystem structure. We find that (i) the rainy season onset precedes and is an effective predictor of the growing season onset in African grasslands. (ii) African woodlands generally have early green-up before rainy season onset and have a variable delayed senescence period after the rainy season, with this delay correlated nonlinearly with tree fraction. These woodland responses suggest their complex water use mechanisms (either from potential groundwater use by relatively deep roots or stem-water reserve) to maintain dry season activity. (iii) We empirically find that the rainy season length has strong nonlinear impacts on tree fractional cover in the annual rainfall range from 600 to 1800 mm/yr, which may lend some support to the previous modeling study that given the same amount of total rainfall to the tree fraction may first increase with the lengthening of rainy season until reaching an “optimal rainy season length,” after which tree fraction decreases with the further lengthening of rainy season. This nonlinear response is resulted from compound mechanisms of hydrological cycle, fire, and other factors. We conclude that African savannas and deciduous woodlands have distinctive responses in their phenology and ecosystem functioning to rainy season. Further research is needed to address interaction between groundwater and tropical woodland as well as to explicitly consider the ecological significance of rainy season length under climate change

A qualitative interview study comparing and contrasting resident and staff perspectives of engaging in meaningful activity in a UK care home.

The provision of meaningful activities in care homes is essential for maintaining residents' mental and physical health, yet many do not get adequate opportunities to participate. This qualitative study explored resident and staff perceptions of engaging in meaningful activities in a residential care home for older people (aged over 65 years) in South London, UK. Nine residents and eleven staff members were recruited and their experiences explored through semi-structured interviews. Data were analysed thematically, and three themes emerged. (1) Appreciation of activity: both staff and residents were aware of the benefits of activity to physical and mental health, yet there was a lack of provision within the home. (2) Residents' desire for engagement: residents perceived themselves as active individuals who had previously enjoyed activities, and had goals that they wanted to achieve. This was in contrast to views of care staff, who perceived residents as inactive, lacking in motivation and sedentary due to intrinsic factors such as their age. (3) Impact of care home culture and physical space: staff and residents perceived different barriers to activity; staff reported they were often expected to take on multiple roles within the home leading to a lack of time to engage residents in activities, whilst residents perceived that the layout and design of the home hindered provision. It was concluded that comparing and contrasting views of residents and staff could assist residential homes to reach greater levels of shared understanding of activity provision and highlight particular areas to target for increasing activity engagement