63 research outputs found
Photonic Entanglement for Fundamental Tests and Quantum Communication
Entanglement is at the heart of fundamental tests of quantum mechanics like
tests of Bell-inequalities and, as discovered lately, of quantum computation
and communication. Their technological advance made entangled photons play an
outstanding role in entanglement physics. We give a generalized concept of
qubit entanglement and review the state of the art of photonic experiments.Comment: 54 pages, 33 figures. Review article submitted to QIC (Rinton
Cutting Optimal Sections from Production Foils
Rechargeable Lithium-Ion battery cell production is one of the most important processes in the field of electro mobility. The batteries’ electrodes are produced in the form of long coated foils which are then cut into pieces of a predefined length called electrode sheets. The production process of the coated foils consists of several sequential process steps and quality parameters are measured frequently along the foil after each sub-process.We aim at determining the maximum number of electrode sheets that can be built from a produced foil of a certain length, with respect to given quality requirements. In a second step, we introduce an algorithm originated from the 0-1 multi-objective knapsack problem that is able to efficiently determine the optimal positions of the sheets based on all observed quality parameters
The speed of quantum information and the preferred frame: analysis of experimental data
The results of EPR experiments performed in Geneva are analyzed in the frame
of the cosmic microwave background radiation, generally considered as a good
candidate for playing the role of preferred frame. We set a lower bound for the
speed of quantum information in this frame at 1.5 x 10^4 c.Comment: 9 pages including 3 figure
A ventricular fibrillation cardiac arrest model with extracorporeal cardiopulmonary resuscitation in rats: 8 minutes arrest time leads to increased myocardial damage but does not increase neuronal damage compared to 6 minutes
IntroductionExtracorporeal cardiopulmonary resuscitation (ECPR) is an emerging strategy in highly selected patients with refractory cardiac arrest (CA). Animal models can help to identify new therapeutic strategies to improve neurological outcome and cardiac function after global ischemia in CA. Aim of the study was to establish a reproducible ECPR rat model of ventricular fibrillation CA (VFCA) that leads to consistent neuronal damage with acceptable long-term survival rates, which can be used for future research.Materials and methodsMale Sprague Dawley rats were resuscitated with ECPR from 6 min (n = 15) and 8 min (n = 16) VFCA. Animals surviving for 14 days after return of spontaneous resuscitation (ROSC) were compared with sham operated animals (n = 10); neurological outcome was assessed daily until day 14. In the hippocampal cornu ammonis 1 region viable neurons were counted. Microglia and astrocyte reaction was assessed by Iba1 and GFAP immunohistochemistry, and collagen fibers in the myocardium were detected in Azan staining. QuPath was applied for quantification.ResultsOf the 15 rats included in the 6 min CA group, all achieved ROSC (100%) and 10 (67%) survived to 14 days; in the 8 min CA group, 15 (94%) achieved ROSC and 5 (31%) reached the endpoint. All sham animals (n = 10) survived 2 weeks. The quantity of viable neurons was significantly decreased, while the area displaying Iba1 and GFAP positive pixels was significantly increased in the hippocampus across both groups that experienced CA. Interestingly, there was no difference between the two CA groups regarding these changes. The myocardium in the 8 min CA group exhibited significantly more collagen fibers compared to the sham animals, without differences between 6- and 8-min CA groups. However, this significant increase was not observed in the 6 min CA group.ConclusionOur findings indicate a uniform occurrence of neuronal damage in the hippocampus across both CA groups. However, there was a decrease in survival following an 8-min CA. Consequently, a 6-min duration of CA resulted in predictable neurological damage without significant cardiac damage and ensured adequate survival rates up to 14 days. This appears to offer a reliable model for investigating neuroprotective therapies
Quantum Cryptography
Quantum cryptography could well be the first application of quantum mechanics
at the individual quanta level. The very fast progress in both theory and
experiments over the recent years are reviewed, with emphasis on open questions
and technological issues.Comment: 55 pages, 32 figures; to appear in Reviews of Modern Physic
Space-QUEST: Experiments with quantum entanglement in space
The European Space Agency (ESA) has supported a range of studies in the field
of quantum physics and quantum information science in space for several years,
and consequently we have submitted the mission proposal Space-QUEST (Quantum
Entanglement for Space Experiments) to the European Life and Physical Sciences
in Space Program. We propose to perform space-to-ground quantum communication
tests from the International Space Station (ISS). We present the proposed
experiments in space as well as the design of a space based quantum
communication payload.Comment: 4 pages, 1 figure, accepted for the 59th International Astronautical
Congress (IAC) 200
Advances in modelling of biomimetic fluid flow at different scales
The biomimetic flow at different scales has been discussed at length. The need of looking into the biological surfaces and morphologies and both geometrical and physical similarities to imitate the technological products and processes has been emphasized. The complex fluid flow and heat transfer problems, the fluid-interface and the physics involved at multiscale and macro-, meso-, micro- and nano-scales have been discussed. The flow and heat transfer simulation is done by various CFD solvers including Navier-Stokes and energy equations, lattice Boltzmann method and molecular dynamics method. Combined continuum-molecular dynamics method is also reviewed
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus
Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. DNA methylation in whole blood captures genetic and environmental influences and is assessed in transethnic meta-analysis of epigenome-wide association studies (EWAS) of serum urate (discovery, n = 12,474, replication, n = 5522). The 100 replicated, epigenome-wide significant (p < 1.1E–7) CpGs explain 11.6% of the serum urate variance. At SLC2A9, the serum urate locus with the largest effect in genome-wide association studies (GWAS), five CpGs are associated with SLC2A9 gene expression. Four CpGs at SLC2A9 have significant causal effects on serum urate levels and/or gout, and two of these partly mediate the effects of urate-associated GWAS variants. In other genes, including SLC7A11 and PHGDH, 17 urate-associated CpGs are associated with conditions defining metabolic syndrome, suggesting that these CpGs may represent a blood DNA methylation signature of cardiometabolic risk factors. This study demonstrates that EWAS can provide new insights into GWAS loci and the correlation of serum urate with other complex traits
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