Simultaneous observations of haemolymph flow and ventilation in marine spider crabs at different temperatures: a flow weighted MRI study

In vivo magnetic resonance imaging (MRI) and angiography were applied to the marine spider crab Maja squinado for a study of temperature effects and thermal tolerance. Ventilation and haemolymph circulation were investigated during progressive cooling from 12°C to 2°C. The anatomical resolution of MR images from Maja squinado obtained with a standard spin echo sequence were suitable to resolve the structures of various internal organs. The heart of the animal could be depicted without movement artifacts. The use of a flow compensated gradient echo sequence allowed simultaneous observations of ventilation, reflected by water flow through the gill chambers as well as of haemolymph flow. Simultaneous investigation of various arteries was possible by use of flow weighted MRI. In addition to those accessible by standard invasive flow sensitive doppler sensors, flow changes in gill, leg arteries and the venous return could be observed. Both ventilation and haemolymph flow decreased during progressive cooling and changes in haemolymph flow varied between arteries. Haemolymph flow through the Arteria sternalis, some gill and leg arteries was maintained at low temperatures indicating a reduced thermal sensitivity of flow in selected vessels. In support of previous invasive studies of haemolymph flow as well as heart and ventilation rates, the results demonstrate that the operation of gills and the maintenance of locomotor activity are critical for cold tolerance. A shift in haemolymph flow between arteries likely occurs to ensure the functioning of locomotion and ventilation in the cold

The Shape of Covariantly Smeared Sources in Lattice QCD

Covariantly smeared sources are commonly used in lattice QCD to enhance the projection onto the ground state. Here we investigate the dependence of their shape on the gauge field background and find that the presence of localized concentrations of magnetic field can lead to strong distortions which reduce the smearing radii achievable by iterative smearing prescriptions. In particular, as $a\to 0$, iterative procedures like Jacobi smearing require increasingly large iteration counts in order to reach physically-sized smearing radii $r_{sm}\sim$ 0.5 fm, and the resulting sources are strongly distorted. To bypass this issue, we propose a covariant smearing procedure (``free-form smearing'') that allows us to create arbitrarily shaped sources, including in particular Gaussians of arbitrary radius.Comment: 1+15 pages, 7 figures (24 pdf images

Optimization of Multiple-Rendezvous Low-Thrust Missions on General-Purpose Graphics Processing Units

A massively parallel method for the identification of optimal sequences of targets in multiple-rendezvous low-thrust missions is presented. Given a list of possible targets, a global search of sequences compatible with the mission requirements is performed. To estimate the feasibility of each transfer, a heuristic model based on Lambert's transfers is evaluated in parallel for each target, making use of commonly available general-purpose graphics processing units such as the Nvidia Tesla cards. The resulting sequences are ranked by user-specified criteria such as length or fuel consumption. The resulting preliminary sequences are then optimized to a full low-thrust trajectory using classical methods for each leg. The performance of the method is discussed as a function of various parameters of the algorithm. The efficiency of the general-purpose graphics processing unit implementation is demonstrated by comparing it with a traditional CPU-based branch-and-bound method. Finally, the algorithm is used to compute asteroid sequences used in a solution submitted to the seventh edition of the Global Trajectory Optimization Competition

Numerical techniques for lattice QCD in the ϵ\epsilon--regime

In lattice QCD it is possible, in principle, to determine the parameters in the effective chiral lagrangian (including weak interaction couplings) by performing numerical simulations in the $\epsilon$--regime, i.e. at quark masses where the physical extent of the lattice is much smaller than the Compton wave length of the pion. The use of a formulation of the lattice theory that preserves chiral symmetry is attractive in this context, but the numerical implementation of any such approach requires special care in this kinematical situation due to the presence of some very low eigenvalues of the Dirac operator. We discuss a set of techniques (low-mode preconditioning and adapted-precision algorithms in particular) that make such computations numerically safe and more efficient by a large factor.Comment: Plain TeX source, 32 pages, figures include

Numerical simulation of heavy fermions in an SU(2)_L x SU(2)_R symmetric Yukawa model

An exploratory numerical study of the influence of heavy fermion doublets on the mass of the Higgs boson is performed in the decoupling limit of a chiral $\rm SU(2)_L \otimes SU(2)_R$ symmetric Yukawa model with mirror fermions. The behaviour of fermion and boson masses is investigated at infinite bare quartic coupling on $4^3 \cdot 8$, $6^3 \cdot 12$ and $8^3 \cdot 16$ lattices. A first estimate of the upper bound on the renormalized quartic coupling as a function of the renormalized Yukawa-coupling is given.Comment: 15 pp + 11 Figures appended as Postscript file

K-->pipi amplitudes from lattice QCD with a light charm quark

We compute the leading-order low-energy constants of the DeltaS=1 effective weak Hamiltonian in the quenched approximation of QCD with up, down, strange, and charm quarks degenerate and light. They are extracted by comparing the predictions of finite volume chiral perturbation theory with lattice QCD computations of suitable correlation functions carried out with quark masses ranging from a few MeV up to half of the physical strange mass. We observe a large DeltaI=1/2 enhancement in this corner of the parameter space of the theory. Although matching with the experimental result is not observed for the DeltaI=1/2 amplitude, our computation suggests large QCD contributions to the physical DeltaI=1/2 rule in the GIM limit, and represents the first step to quantify the role of the charm quark-mass in K-->pipi amplitudes.Comment: 4 pages, 1 figure. Minor modifications. Final version to appear on PR

Malaria parasite detection increases during pregnancy in wild chimpanzees

Background: The diversity of malaria parasites (Plasmodium sp.) infecting chimpanzees (Pan troglodytes) and their close relatedness with those infecting humans is well documented. However, their biology is still largely unexplored and there is a need for baseline epidemiological data. Here, the effect of pregnancy, a well-known risk factor for malaria in humans, on the susceptibility of female chimpanzees to malaria infection was investigated. Methods: A series of 384 faecal samples collected during 40 pregnancies and 36 post-pregnancies from three habituated groups of wild chimpanzees in the Tai National Park, Cote d'Ivoire, were tested. Samples were tested for malaria parasites by polymerase chain reaction (PCR) and sequencing. Data were analysed using a generalized linear mixed model. Results: Probability of malaria parasite detection significantly increased towards the end of pregnancy and decreased with the age of the mother. Conclusions: This study provides evidence that susceptibility to malaria parasite infection increases during pregnancy, and, as shown before, in younger individuals, which points towards similar dynamics of malaria parasite infection in human and chimpanzee populations and raises questions about the effects of such infections on pregnancy outcome and offspring morbidity/mortality