Workbench for creating block-based environments

Block-based environments are visual-programming environments that allow users to create programs by dragging and dropping blocks that resemble jigsaw puzzle pieces. These environments have proven to lower the entry barrier of programming for end-users. Besides using block-based environments for programming, they can also help edit popular semi-structured data languages such as JSON and YAML. However, creating new block-based environments is still challenging; developers can develop them in an ad-hoc way or using context-free grammars in a language workbench. Given the visual nature of block-based environments, both options are valid; however, developers have some limitations when describing them. In this paper, we present Blocklybench, which is a meta-block-based environment for describing block-based environments for both programming and semi-structured data languages. This tool allows developers to express the specific elements of block-based environments using the blocks notation. To evaluate Blocklybench, we present three case studies. Our results show that Blocklybench allows developers to describe block-based specific aspects of language constructs such as layout, color, block connections, and code generators

Consensus guidelines for the use and interpretation of angiogenesis assays

The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference