Archaeological Investigations of Sections of the San Pedro (41BX337) and Upper Labor (41BX1273) Acequias in San Antonio, Bexar County, Texas

On January 21 and February 19 of 2020, the Center for Archaeological Research (CAR) excavated five exploratory backhoe trenches within two project areas in central San Antonio, Bexar County, Texas. Project Area 1 is located at 209 E. Fredericksburg Road, and Project Area 2 is at 712 W. Laurel Street. CAR was contracted by the VIA Metropolitan Transit Authority (VIAMTA) to conduct an archaeological investigation of the two locations as they planned to use the areas for employee parking lots. Plans called for the areas to be excavated to a total depth of 25.4 cm (10 in.), with 15.24 cm (6 in.) of new concrete and 10.16 cm (4 in.) of new base. Archival maps suggested that the proposed parking areas could include the intersection of two Spanish Colonial acequias, the San Pedro (41BX337) and the Upper Labor (41BX1273). Both areas are owned by VIA-MTA, a political subdivision of the State of Texas. As such, the work was carried out under Texas Antiquities Permit No. 9229 according to the requirements of the Texas Antiquities Code and the Unified Development Code of the City of San Antonio (COSA). Dr. Raymond Mauldin served as the Principal Investigator, and Sarah Wigley served as the Project Archaeologist. Five backhoe trenches were excavated in the two project areas. Three trenches were excavated in Project Area 1 and encompassed 0.024 ha (0.06 ac.). Two trenches were excavated within Project Area 2 and encompassed 0.089 ha (0.22 ac.). Four features were documented. Feature 1 was identified as a section of the Upper Labor Acequia (41BX1273), and Feature 3 was identified as a section of the San Pedro Acequia (41BX337). Feature 2 was a late construction dump and was found not to be significant. Feature 4 was documented within the channel of Feature 3 and is also part of 41BX337. The San Pedro Acequia (41BX337) has previously been found to be eligible for the National Register of Historic Places (NRHP) and is also eligible for designation as a State Antiquities Landmark (SAL). The Upper Labor Acequia (41BX1273) has been previously recommended as eligible for the NRHP and for designation as a SAL. The acequia is also a contributing resource to Brackenridge Park’s NRHP nomination (National Park Service 2011). Both sites are a part of the San Antonio’s acequia system, which is a designated National Historic Civil Engineering Landmark. CAR recommends that the section of the San Pedro Acequia (41BX337) and the section of the Upper Labor Acequia (41BX1273) documented during the course of this project are eligible for inclusion to the NRHP and for designation as a SAL. However, neither of these sites should be impacted by the proposed parking lot construction that has a maximum depth of impact of 25.4 cm (10 in.), which is a depth above the features. As such, CAR recommends that the construction of both parking areas be allowed to proceed, though with an archaeological monitor present. CAR further recommends that should buried cultural features be encountered during construction work in the immediate area cease and that the Texas Historic Commission (THC) and the COSA Office of Historic Preservation (COSA-OHP) be notified to consult on additional actions that may be necessary to protect the cultural remains. Both the THC and COSA-OHP concurred with the recommendations. However, prior to the issuance of the concurrence documents from the THC, VIA-MTA paved Project Area 2 (712 W. Laurel Street) without notifying CAR. No monitor was present for the excavation or paving. CAR subsequently photographed the area. In addition, VIA-MTA no longer plans to do any work in Project Area 1. No artifacts were collected from Project Area 1, but several historic artifacts were collected from Project Area 2. These artifacts along with all records generated on this project are curated at the CAR facility as accession 2259

Intensive Pedestrian Survey of the Eisenhower Trail Segment,Howard Peak Greenway Trail, San Antonio, Bexar County, Texas

On May 19-21, 2020, the Center for Archaeological Research (CAR) at The University of Texas at San Antonio (UTSA) conducted an intensive pedestrian survey of the Eisenhower Park Trail Segment of the Howard Peak Greenway Trail in northwest San Antonio, Bexar County, Texas. The work was conducted in response to a request from Adams Environmental, Inc. The original alignment of the trail (The Rim to Eisenhower Park) had been surveyed previously by CAR in 2015, but a redesign necessitated a survey of this portion of the trail segment. This portion of the trail was redesigned because the slope of the previous path was steep within the project area, and constructing and maintaining the necessary Americans with Disabilities Act (ADA) compliant grade would have been challenging. The work is sponsored by the City of San Antonio (COSA) Parks and Recreation Department. The project falls under the COSA Unified Development Code as well as the Texas Antiquities Code. The CAR obtained Texas Antiquities Permit No. 9394 prior to the beginning work. Cynthia Munoz served as the Principal Investigator, and Sarah Wigley served as the Project Archaeologist. CAR excavated 22 shovel tests along a 1750 m (1.09 mi.) long and 9.14 m (30 ft.) wide linear area that comprises 0.69 ha (1.7 ac.). One shovel test was positive for cultural material, but delineating shovel tests were negative. Soils within the APE were found to be predominately either fill or extremely shallow. No archaeological sites were recorded during the course of this survey. The CAR recommends that construction proceed as planned. The THC agreed with CAR\u27s recommendation. However, if cultural materials are encountered during project activities, work should cease in the immediate area and the City Archaeologist with the COSA-OHP and the THC should be notified. All records generated during this project and the recovered chert biface are curated at the CAR (accession #2271) in accordance with THC guidelines

Archaeological Monitoring of South Alamo Street Improvements, Pereida Street to César Chávez Boulevard, San Antonio, Bexar County, Texas

From October 31, 2018, through February 13, 2019, the Center for Archaeological Research (CAR) at The University of Texas at San Antonio conducted archaeological monitoring for the South Alamo Street Improvements Project located in downtown San Antonio, Bexar County, Texas. The excavation of 20 boreholes and more than 772 meters of trench were monitored. The work was performed for the City of San Antonio (COSA) to fulfill the requirements of the COSA’s Unified Development Code and the Antiquities Code of Texas. The project was conducted under Texas Antiquities Permit No. 8563. Dr. Paul Shawn Marceaux, CAR Director, served as the Principal Investigator, and Sarah Wigley served as the Project Archaeologist. The project area is located on COSA property along South Alamo Street between César Chávez Boulevard and Pereida Street in central San Antonio. The monitoring consisted of trenching for the installation of an electrical conduit and the excavation of boreholes for new light poles located on either side of South Alamo Street between Turner Street and Pereida Street. The project area runs directly through the two national Historic Districts, the Lavaca Neighborhood Historic District and the South Alamo Street-South St. Mary’s Street Historic District, and it is included in the two local Historic Districts (the Lavaca Neighborhood and King William Historic District). These Historic Districts are known to contain significant historic sites, including the Acequia Madre de Valero (41BX8) and the Concepción Acequia (41BX1887; COSA Office of Historic Preservation 2019a). During the monitoring, part of an intact wall of the Acequia Madre de Valero (41BX8) was uncovered near the intersection of Beauregard Street on the west side of South Alamo Street, although documentation of the feature was limited to the extent of the utility trench. In addition to the acequia wall section, five other architectural features, some potentially Spanish Colonial in nature, were documented, and four new sites designated 41BX2286, 41BX2287, 41BX2288, and 41BX2289 were recorded. A small number of temporally diagnostic historic artifacts were collected during the course of the project. The CAR recommends that the section of 41BX8 (Acequia Madre de Valero) documented during the course of this project is eligible for inclusion to the National Register of Historical Places (NRHP) and designation as a State Antiquities Landmark (SAL), and all impacts should be avoided. Site 41BX8 has previously been determined to be eligible for inclusion on the NRHP, and it is designated as a Historic American Engineering Record and a Recorded Texas Historic Landmark (THC 2019). The portion of the site that was encountered during monitoring remains intact. It was covered with a protective layer of sand before backfilling. Site 41BX2286, a portion of a historic limestone and mortar wall, should also be avoided until its significance can be more clearly defined. Currently, the CAR cannot determine this site’s potential eligibility for inclusion to the NRHP or listing as a SAL due to the limited nature of the investigation. The portion of the site documented during monitoring remains intact. It was covered with a protective layer of sand before backfilling. The CAR recommends that sites 41BX2287, 41BX2288, and 41BX2289 are not significant. The portions of these sites documented during monitoring remain intact and were covered with a protective layer of sand before backfilling. These three sites are not recommended as eligible for inclusion to the NRHP or for designation as SAL. All artifacts collected during the course of this project are curated at the CAR. All forms, documents, and photographs complied during the project and a copy of this report are archived in Project Accession file 2180 at the CAR

Archaeological Investigations within San Pedro Springs Park (41BX19), San Antonio, Bexar County, Texas

The University of Texas at San Antonio Center for Archaeological Research (UTSA-CAR) contracted with Adams Environmental, Inc. to provide archaeological services to Capital Improvement Management (CIMS) of the City of San Antonio (COSA) related to the archaeological investigation of selected areas of San Pedro Springs Park in San Antonio, Bexar County, Texas. The CAR conducted archaeological testing at this National Register Site, 41BX19, from early December 2013 to mid-January of 2014. The goals of archaeological investigations were to identify and investigate any proto-historic and historic archaeological deposits associated with Colonial Period occupants of the area, including evidence of the first acequia and associated dam, and the location of the first presidio and villa. In addition, CAR was tasked with the investigation of any prehistoric cultural deposits encountered. This project was performed by staff archaeologists from the CAR. It was conducted under Texas Antiquities Permit No. 6727, with Dr. Steve Tomka serving as Principal Investigator (PI), and Kristi Nichols and Stephen Smith serving as Project Archaeologists. Dr. Tomka departed from UTSA shortly after the completion of fieldwork. At that time, Dr. Raymond Mauldin of CAR assumed PI responsibilities for the project. One hundred and eleven shovel tests, eleven 1-x-1 m test units, two 50-x-50 cm units, two backhoe trenches, and several auger holes were excavated during this effort. Minimal artifactual evidence of colonial occupants was noted during the archaeological investigations. Several Native American bone tempered sherds that could reflect either Late Prehistoric Leon Plain or Goliad ware were recovered. However, no Spanish Majolicas or lead glazed wares were uncovered, and no gunflints were identified in the lithic assemblage. Due to various utility lines and other obstructions, backhoe trenches to search for the acequia and associated dam could not be excavated. It is likely that areas proposed for investigation of the acequia and associated dam have been disturbed by aforementioned utility lines as well as earlier construction within the park. No evidence of the specific location of the first presidio or villa was located. Shovel testing and test units revealed the presence of historic and prehistoric use of the park, though mixing of historic and prehistoric material, as well as other disturbances (e.g., rodents), was common in the deposits. However, there was an increase in prehistoric material with depth as revealed in shovel testing results. Shovel testing located Feature 1, a burned rock feature that possibly was associated with a sheet midden, as well as several areas with high densities of prehistoric materials. Test excavations, based on these shovel tests, suggest that Feature 1 is a discrete feature that lies below a widespread, low-density distribution of burned rock. Shovel testing also identified a high-density cluster of lithic, bone, and burned rock. The excavation of a 1-x-1 m test unit (TU 4) in this area produced over 4,000 pieces of debitage, with over 50% of this total coming from three levels. Burned rock, a variety of tools, faunal material, and charcoal were present throughout these levels. Temporal placement of deposits relied on artifact typologies (e.g., ceramic types, lithic projectile points, lithic tool types) as well as two charcoal and four bone collagen radiocarbon dates. Artifact typologies suggest occupation as early as the Early Archaic as reflected by a possible Guadalupe tool. A series of Late Archaic Points (Castroville, Frio, Marcos, and Montell) and Late Prehistoric point forms (Edwards, Perdiz, and Scallorn) are present from several areas. In addition, a possible Middle Archaic La Jita point was recovered. The bone tempered Native American wares could date as early as AD 1250, though they could also reflect proto-historic or colonial age materials. Other ceramics primarily suggest a mid-nineteenth- to midtwentieth- century occupation. Using the midpoints of the 1-sigma distribution, calibrated radiocarbon dates show use of San Pedro Park from as early as 100 AD (CAR 345; 1905 +/- 22 Radiocarbon Years Before Present [RCYBP]) to as recently as the early twentieth century. The more recent end of that range is a function of two late dates from two different areas of the park. The first of these is on a bison bone (CAR 344) that returned a date of 158 +/- 23 RCYBP. The second is on a bone consistent with a bison-sized animal (CAR 346) that produced a date of 155 +/- 23 RCYBP. The corrected, calibrated dates for these two samples range from AD 1670 to the early 1940s using the 1-sigma spread. The wide range of these dates is related to the flat calibration curve late in time. However, the most probable date range (ca. 36% probability) for these two dates is between AD 1729 and 1779, with a roughly 48% probability that they date prior to AD 1779. Limited testing suggests that, with a few specific exceptions, the upper 30-40 cm of San Pedro Park is extensively disturbed. However, though some disturbances are present, at least three areas have materials in what appears to be good context. These include material dating to the Late Archaic, Late Prehistoric, and possibly the Proto-historic or Colonial Period. Based on historic maps, previous work, and the current investigation, CAR proposes a series of management areas for San Pedro Park. If work in these management areas follows these suggestions for various limits on subsurface impacts, CAR recommends that renovation activities within the park be allowed to proceed. The Texas Historical Commission (THC), in a letter dated February 4, 2015, agreed with these recommendations. Finally, CAR provides several recommendations for public education facilities within the park. In accordance with the THC Permit specifications and the Scope of Work for this project, all field notes, analytical notes, photographs, and other project related documents, along with a copy of the final report, will be curated at the CAR. After quantification and completion of analysis, and in consultation with THC and the COSA Office of Historic Preservation, artifacts possessing little scientific value were discarded pursuant to Chapter 26.27(g)(2) of the Antiquities Code of Texas. Artifact classes discarded specific to this project included samples of burned rock and snail shell, all unidentifiable metal, soil samples, and recent (post-1950) material

NamesforLife Semantic Resolution Services for the Life Sciences

A major challenge in bioinformatics, life sciences, and medicine is using correct and informative names. While this sounds simple enough, many different naming conventions exist in the life sciences and medicine that may be either complementary or competitive with other naming conventions. For a variety of reasons, proper names are not always used, leading to an accumulated semantic ambiguity that readers of the literature and end users of databases are left to resolve on their own. This ambiguity is a growing problem and the biocuration community is aware of its consequences. 

To assist those confronted with ambiguous names (which not only includes researchers but clinicians, manufacturers, patent attorneys, and others who use biological data in their routine work), we developed a generalizable semantic model that represents names, concepts, and exemplars (representations of biological entities) as distinct objects. By identifying each object with a Digital Object Identifier (DOI) it becomes possible to place forward-pointing links in the published literature, in databases, and vector graphics that can be used as part of a mechanism for resolving ambiguities, thereby “future proofing” a nomenclature or terminology. A full implementation of the N4L model for the _Bacteria_ and _Archaea_ was released in April, 2010. The system is professionally curated and represents a Tier III resource in Parkhill’s view of bioinformatic services. A variety of tools and web services have been developed for readers, publishers, and others (N4L Guide, N4L Autotagger, N4L Semantic Search, N4L Taxonomic Abstracts) and we are incorporating other taxonomies into the N4L data model, as well as adding additional phenotypic, genotypic, and genomic information to the existing exemplars to add greater value to end users

Archaeological Investigations within San Pedro Springs Park (41BX19), San Antonio, Bexar County, Texas

The University of Texas at San Antonio Center for Archaeological Research (UTSA-CAR) contracted with Adams Environmental, Inc. to provide archaeological services to Capital Improvement Management (CIMS) of the City of San Antonio (COSA) related to the archaeological investigation of selected areas of San Pedro Springs Park in San Antonio, Bexar County, Texas. The CAR conducted archaeological testing at this National Register Site, 41BX19, from early December 2013 to mid-January of 2014. The goals of archaeological investigations were to identify and investigate any proto-historic and historic archaeological deposits associated with Colonial Period occupants of the area, including evidence of the first acequia and associated dam, and the location of the first presidio and villa. In addition, CAR was tasked with the investigation of any prehistoric cultural deposits encountered. This project was performed by staff archaeologists from the CAR. It was conducted under Texas Antiquities Permit No. 6727, with Dr. Steve Tomka serving as Principal Investigator (PI), and Kristi Nichols and Stephen Smith serving as Project Archaeologists. Dr. Tomka departed from UTSA shortly after the completion of fieldwork. At that time, Dr. Raymond Mauldin of CAR assumed PI responsibilities for the project. One hundred and eleven shovel tests, eleven 1-x-1 m test units, two 50-x-50 cm units, two backhoe trenches, and several auger holes were excavated during this effort. Minimal artifactual evidence of colonial occupants was noted during the archaeological investigations. Several Native American bone tempered sherds that could reflect either Late Prehistoric Leon Plain or Goliad ware were recovered. However, no Spanish Majolicas or lead glazed wares were uncovered, and no gunflints were identified in the lithic assemblage. Due to various utility lines and other obstructions, backhoe trenches to search for the acequia and associated dam could not be excavated. It is likely that areas proposed for investigation of the acequia and associated dam have been disturbed by aforementioned utility lines as well as earlier construction within the park. No evidence of the specific location of the first presidio or villa was located. Shovel testing and test units revealed the presence of historic and prehistoric use of the park, though mixing of historic and prehistoric material, as well as other disturbances (e.g., rodents), was common in the deposits. However, there was an increase in prehistoric material with depth as revealed in shovel testing results. Shovel testing located Feature 1, a burned rock feature that possibly was associated with a sheet midden, as well as several areas with high densities of prehistoric materials. Test excavations, based on these shovel tests, suggest that Feature 1 is a discrete feature that lies below a widespread, low-density distribution of burned rock. Shovel testing also identified a high-density cluster of lithic, bone, and burned rock. The excavation of a 1-x-1 m test unit (TU 4) in this area produced over 4,000 pieces of debitage, with over 50% of this total coming from three levels. Burned rock, a variety of tools, faunal material, and charcoal were present throughout these levels. Temporal placement of deposits relied on artifact typologies (e.g., ceramic types, lithic projectile points, lithic tool types) as well as two charcoal and four bone collagen radiocarbon dates. Artifact typologies suggest occupation as early as the Early Archaic as reflected by a possible Guadalupe tool. A series of Late Archaic Points (Castroville, Frio, Marcos, and Montell) and Late Prehistoric point forms (Edwards, Perdiz, and Scallorn) are present from several areas. In addition, a possible Middle Archaic La Jita point was recovered. The bone tempered Native American wares could date as early as AD 1250, though they could also reflect proto-historic or colonial age materials. Other ceramics primarily suggest a mid-nineteenth- to midtwentieth-century occupation. Using the midpoints of the 1-sigma distribution, calibrated radiocarbon dates show use of San Pedro Park from as early as 100 AD (CAR 345; 1905 +/- 22 Radiocarbon Years Before Present [RCYBP]) to as recently as the early twentieth century. The more recent end of that range is a function of two late dates from two different areas of the park. The first of these is on a bison bone (CAR 344) that returned a date of 158 +/- 23 RCYBP. The second is on a bone consistent with a bison-sized animal (CAR 346) that produced a date of 155 +/- 23 RCYBP. The corrected, calibrated dates for these two samples range from AD 1670 to the early 1940s using the 1-sigma spread. The wide range of these dates is related to the flat calibration curve late in time. However, the most probable date range (ca. 36% probability) for these two dates is between AD 1729 and 1779, with a roughly 48% probability that they date prior to AD 1779. Limited testing suggests that, with a few specific exceptions, the upper 30-40 cm of San Pedro Park is extensively disturbed. However, though some disturbances are present, at least three areas have materials in what appears to be good context. These include material dating to the Late Archaic, Late Prehistoric, and possibly the Proto-historic or Colonial Period. Based on historic maps, previous work, and the current investigation, CAR proposes a series of management areas for San Pedro Park. If work in these management areas follows these suggestions for various limits on subsurface impacts, CAR recommends that. renovation activities within the park be allowed to proceed. The Texas Historical Commission (THC), in a letter dated February 4, 2015, agreed with these recommendations. Finally, CAR provides several recommendations for public education facilities within the park. In accordance with the THC Permit specifications and the Scope of Work for this project, all field notes, analytical notes, photographs, and other project related documents, along with a copy of the final report, will be curated at the CAR. After quantification and completion of analysis, and in consultation with THC and the COSA Office of Historic Preservation, artifacts possessing little scientific value were discarded pursuant to Chapter 26.27(g)(2) of the Antiquities Code of Texas. Artifact classes discarded specific to this project included samples of burned rock and snail shell, all unidentifiable metal, soil samples, and recent (post-1950) material

Devon design sprint report : June 2023

Over the course of five days, a group of stakeholders involved in the land use decision-making process in Devon worked together as a team to create a prototype decision support tool aimed at facilitating carbon-focused land use decisions in the rural environment. After the prototype was developed, it was tested by a range of intended users to assess its usability and effectiveness. The work presented here was funded by the Geospatial Commission as part of the National Land Data Programme which fed into the Devon Land Use Framework. Land is a finite resource. In the UK the limited land area and growing population makes managing competing priorities and land use functions particularly complex. Land use is often multifunctional and yet is subject to various trade-offs. The design sprint focused on long-term carbon sequestration and storage in rural land use decisions, with an understanding that carbon forms a component of a range of ecosystem services. Spatial data and modelling tools provide an opportunity to support the assessment, planning and management of land use. The design sprint team began by identifying pinch points in the decision-making process where geospatial data and tools might support land managers and their advisors to make and influence land use decisions. The team worked collaboratively on designing a prototype decision support tool that addressed these pinch points. The key requirements the team agreed to incorporate into the prototype were: ›› Baseline and future land cover options; ›› Clear summary of economic incentives and impact of any land use changes; ›› Simple and easy to use; The user testing demonstrated the need for shared digital evidence upon which to base conversations at both the strategic and granular/ site scale. This included using field-scale data wherever possible to facilitate conversations at both on-farm and landscape scales. Users also said they wanted functionality that could support the creation of a ‘community of change’ to help people work together to leverage better environmental, social and financial outcomes. The design sprint and prototype led to an understanding that a suite of spatially explicit data and decision support tools is integral to a land use framework. Having access to easy-to-use data is a critical part of having informed discussions around land use change. A shared evidence base is central to ensuring that leaders and local stakeholders are able to understand and communicate the benefits, trade-offs and shared outcomes possible from land use decision making

Thieno[2,3-b]pyridine derivatives are potent anti-platelet drugs, inhibiting platelet activation, aggregation and showing synergy with aspirin

Drugs which inhibit platelet function are commonly used to prevent blood clot formation in patients with Acute Coronary Syndromes (ACS) or those at risk of stroke. The thieno[3,2-c]pyridine class of therapeutic agents, of which clopidogrel is the most commonly used, target the P2Y12 receptor, and are often used in combination with acetylsalicylic acid (ASA). Six thieno[2,3-b]pyridine were assessed for in vitro anti-platelet activity; all derivatives showed effects on both platelet activation and aggregation, and showed synergy with ASA. Some compounds demonstrated greater activity when compared to clopidogrel. These compounds, therefore, represent potential novel P2Y12 inhibitors for improved treatment for patients

Restaurant cooking trends and increased risk for Campylobacter infection

In the United Kingdom, outbreaks of Campylobacter infection are increasingly attributed to undercooked chicken livers, yet many recipes, including those of top chefs, advocate short cooking times and serving livers pink. During 2015, we studied preferences of chefs and the public in the United Kingdom and investigated the link between liver rareness and survival of Campylobacter. We used photographs to assess chefs’ ability to identify chicken livers meeting safe cooking guidelines. To investigate the microbiological safety of livers chefs preferred to serve, we modeled Campylobacter survival in infected chicken livers cooked to various temperatures. Most chefs correctly identified safely cooked livers but overestimated the public’s preference for rareness and thus preferred to serve them more rare. We estimated that 19%-52% of livers served commercially in the United Kingdom fail to reach 70°C and that predicted Campylobacter survival rates are 48%-98%. These findings indicate that cooking trends are linked to increasing Campylobacter infections

Tracking uncertainties in the causal chain from human activities to climate

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95537/1/grl25489.pd