39 research outputs found
Entrepreneurial learning in practice: The impact of knowledge transfer
The aim of this research is to provide perspectives on how entrepreneurial practitioners, specifically owners of high-tech
small firms (HTSFs), engage with knowledge transfer and learn. The authors draw on extant research and report on the
views and observations of the principals in two case study companies in the HTSF sector with regard to growing their
ventures and developing learning while part of a Knowledge Transfer Partnership (KTP) programme. Entrepreneurial
learning is an area of significant interest due to the growth of entrepreneurship and the varied ways in which learning can
take place. There are many different interventions that can be used to transfer knowledge and develop learning, but there
is limited, if any, consensus on their respective effectiveness. The researchers used an ethnographic approach in two
companies over an 18-month period. The study concludes that the KTP intervention facilitates an opportunity for learning
through disruption, with the key barrier to any new learning being established practice. Interestingly, the findings suggest
that entrepreneurial learning is greatly facilitated by ‘on-the-job’ learning
Case study insights to the impact of knowledge transfer in high-tech small firms on entrepreneurial practitioner learning
Knowledge transfer, as the term suggests, is about the exchange of knowledge between associates in a partnership. The ambition of such knowledge transfer is the pursuit and exploitation of new, innovative opportunities and the facilitation of learning. The theatre for such activity is, largely, within high technology small to medium sized firms. The partnership commonly includes those within a business venture, an academic or team of academics from a Higher Education Institute, (HEI), and government agencies. It is essentially about the transfer of tangible and intellectual property, expertise, learning and skills between academia and the non-academic community, particularly the business community. The ‘knowledge’ transferred can be formal and clearly expressed, for example, from published research, informal in terms of individual experiences and tacit as in residing in the individual without being stated and therefore difficult to articulate in direct communication. Transferring knowledge, particularly tacit knowledge, and facilitating learning, is a complex undertaking. The entrepreneurial business venturer, for example, busy with developing an enterprise, may not be fully aware of, or have thought critically about, the wealth of knowledge that resides within him/her as a consequence of years of business experience. The specific challenge to transfer ‘knowledge’ is therefore to capture, organize, create, and distribute such knowledge from one part of an enterprise to another or indeed throughout an enterprise in ways that effect a step-change in the progress of the business venture and to ensure its legacy remains valid for those within the enterprise into the future though the development of appropriate applied learning. The Knowledge Transfer Partnership, (KTP), scheme in the UK, is specifically designed to help those within entrepreneurial firms to acquire the knowledge they need to pursue growth through a greater commitment to, and development of, competencies in innovation practice and opportunity focus. The link between the entrepreneurial business venturer, the academic in the HEI and the graduate, the Associate, recruited by the HEI and lodged within the firm, are the key players in determining the potential of the scheme to facilitate learning that will have a positive impact on the future of the business. The Associate, as an agent for positive, innovative change in the business, brings with him/her new knowledge to be introduced into the business, challenging established practices and processes and supporting innovative step-changes in the business. The placements are temporary but potentially can be a ‘long-interview’. In a recent independent report, (The Knowledge Transfer Partnership programme: an impact review, From: Innovate UK, First published: 13 October 2015), it was noted, for example, that for every £1 of KTP grant invested up to £8 of net extra GVA was generated, that 94% of associates said KTP had had a positive impact on their personal/career development, that over a third said the impact had actually been transformational for their development and career, that 99% of knowledge base organisations would recommend the KTP programme and that 95% of KTP associates would recommend it to other graduates/post graduates. Knowledge transfer is, therefore, clearly both potentially valuable and challenging for those engaged in it. Many high-technology small to medium sized firms emerge as a consequence of the creativity and innovativeness of a founding entrepreneur and his or her team and the early development of such enterprises can often be characterised by organic development and considerable adhocracy. Innovation in terms of new product or process development lie at the core of what founders and their teams do although not always formally recognised and supported. Early practices that are seen to work become established. That key focus of knowledge-transfer is on supporting appropriate and sustainable learning, where the Entrepreneurial Practitioner acquires and learns to implement new knowledge of best practice in business development, where the Associate gains experience of business practice and an opportunity to apply learned theory and where the academic learns the value of their research in an applied context. The focus of this research is on the Entrepreneurial Practitioner’s learning. Cope (2003) suggests however that the entrepreneurship discipline does not currently possess sufficient conceptual frameworks to explain how entrepreneurs learn. He concluded ‘..entrepreneurial learning is not characterised by the notions of stability, consistency or predictability. Rather, evidence suggests that the concepts of metamorphosis, discontinuity and change more appropriately encapsulate the dynamics of this phenomenon’, (p. 26). When it comes to working, learning and innovation, Brown and Duguid (1991) argue that ‘Work practice is generally viewed as conservative and resistant to change, learning is generally viewed as distinct from working and problematic in the face of change and innovation is generally viewed as the disruptive but necessary imposition of change on the other two’, (p40), highlighting the tensions that often accompany the learning process within the developing HTSF. In this exploratory, ethnographic report, two of the authors were each embedded in a high-tech small firm as part of a knowledge transfer partnership, (KTP), and in the research key decision-makers in each firm are observed and interviewed over a two-year period in order to gain insights to practitioner learning over that period. In response to Cope’s suggestion, and reflecting those of Brown and Duguid, the authors’ aim is to provide perspectives on how Entrepreneurial Practitioners, owners of high-tech small firms, (HTSF), and engaged with knowledge transfer, learn
Measuring the effect of perceived corruption on detention and incident risk – an empirical analysis
This manuscript uses a global and comprehensive approach based on 1.14 million observations to investigate whether the effect of corruption can be measured towards safety qualities of vessels. Since safety qualities of vessels are influenced by many factors and the effect of corruption can be confounded by their interactions, a multi-step approach in used at ship. The findings confirm the hypothesis that port states with higher perceived corruption are less likely to detain vessels and that flag states or ship owners located in countries associated with higher perceived corruption are more likely to have very serious incidents as the operating environment might facilitate substandard shipping and weaker enforcement of international conventions or increased operating costs that can influence safety qualities of vessels in economic hardship. The findings also revealed the degree of underreporting for serious incidents by flag states. The results support the establishment of accountability frameworks and current efforts at the International Maritime Organization (IMO) to address corruption to support sustainable development goal 16 (SDG 16). Relevant policy implications could be to strengthen the fight against corruption via IMO’s Member State Audit Scheme and Facilitation Committee in general and specifically by strengthening training and enforcement of the Code of Good Conduct for Port State Control Inspectors. To enhance transparency, the Global Integrated Ship Information System could be adjusted to include an option to report corruption directly by ship owners and operators to IMO and flag states and mandatory reporting requirements should be revised to capture all serious incidents to GISI
Contribution of electroactive humic substances to the iron-binding ligands released during microbial remineralisation of sinking particles
Microscopic plants and animals in seawater require nutrients to survive. One of these key nutrients is iron, dissolved in seawater at very low concentrations. The growth of around half of the microscopic life in the upper ocean is dependent on the availability of this dissolved iron. These organisms form the bottom of the food chain, and their growth is linked to marine productivity and the drawdown of carbon into the deep ocean, in turn influencing climate change. Because iron tends to not dissolve easily in seawater, it must bind with compounds known as ligands, which help keep iron dissolved. However, processes controlling the composition of this ligand pool are poorly understood. As material sinks through the water column, it is broken down by marine microbes, releasing iron and ligands. Here we have studied the release of iron, ligands, and a specific type of ligand known as humic substances, during the microbial degradation of sinking particles. By doing this, we have identified a large fraction of the released ligand pool. This furthers our understanding of the processes controlling dissolved iron concentrations and distributions in ocean waters, providing key information for biogeochemical modeling and for calculating carbon sequestration in seawater
Amplification ratio control system for copy number variation genotyping
We describe a generic design for ratiometric analysis suitable for determination of copy number variation (CNV) class of a gene. Following two initial sequence-specific PCR priming cycles, both ends of both amplicons (one test and one reference) in a duplex reaction, are all primed by the same universal primer (UP). Following each amplification denaturation step, the UP target and its reverse complement (UP′) in each strand form a hairpin. The bases immediately beyond the 3′-end of the UP and 5′ of UP′ are chosen such as not to base pair in the hairpin (otherwise priming is ablated). This hairpin creates a single constant environment for priming events and chaperones free 3′-ends of amplicon strands. The resultant ‘amplification ratio control system’ (ARCS) permits ratiometric representation of amplicons relative to the original template into PCR plateau phase. These advantages circumvent the need for real-time PCR for quantitation. Choice of different %(G+C) content for the target and reference amplicons allows liquid phase thermal melt discrimination and quantitation of amplicons. The design is generic, simple to set up and economical. Comparisons with real-time PCR and other techniques are made and CNV assays demonstrated for haptoglobin duplicon and ‘chemokine (C-C motif) ligand 3-like 1’ gene
Mathematical modelling of extracellular matrix dynamics using discrete cells: Fiber orientation and tissue regeneration
Matrix orientation plays a crucial role in determining the severity of scar tissue after dermal wounding. We present a model framework which allows us to examine the interaction of many of the factors involved in orientation and alignment. Within this framework, cells are considered as discrete objects, while the matrix is modelled as a continuum. Using numerical simulations, we investigate the effect on alignment of changing cell properties and of varying cell interactions with collagen and fibrin
Chemical shielding of H2O and HF encapsulated inside a C60 cage
Molecular surgery provides the opportunity to study relatively large molecules encapsulated within a fullerene cage. Here we determine the location of an H2O molecule isolated within an adsorbed buckminsterfullerene cage, and compare this to the intrafullerene position of HF. Using normal incidence X-ray standing wave (NIXSW) analysis, coupled with density functional theory and molecular dynamics simulations, we show that both H2O and HF are located at an off-centre position within the fullerene cage, caused by substantial intra-cage electrostatic fields generated by surface adsorption of the fullerene. The atomistic and electronic structure simulations also reveal significant internal rotational motion consistent with the NIXSW data. Despite this substantial intra-cage interaction, we find that neither HF or H2O contribute to the endofullerene frontier orbitals, confirming the chemical isolation of the encapsulated molecules. We also show that our experimental NIXSW measurements and theoretical data are best described by a mixed adsorption site model
Emerging Technologies for the Detection of Rabies Virus: Challenges and Hopes in the 21st Century
The diagnosis of rabies is routinely based on clinical and epidemiological information, especially when exposures are reported in rabies-endemic countries. Diagnostic tests using conventional assays that appear to be negative, even when undertaken late in the disease and despite the clinical diagnosis, have a tendency, at times, to be unreliable. These tests are rarely optimal and entirely dependent on the nature and quality of the sample supplied. In the course of the past three decades, the application of molecular biology has aided in the development of tests that result in a more rapid detection of rabies virus. These tests enable viral strain identification from clinical specimens. Currently, there are a number of molecular tests that can be used to complement conventional tests in rabies diagnosis. Indeed the challenges in the 21st century for the development of rabies diagnostics are not of a technical nature; these tests are available now. The challenges in the 21st century for diagnostic test developers are two-fold: firstly, to achieve internationally accepted validation of a test that will then lead to its acceptance by organisations globally. Secondly, the areas of the world where such tests are needed are mainly in developing regions where financial and logistical barriers prevent their implementation. Although developing countries with a poor healthcare infrastructure recognise that molecular-based diagnostic assays will be unaffordable for routine use, the cost/benefit ratio should still be measured. Adoption of rapid and affordable rabies diagnostic tests for use in developing countries highlights the importance of sharing and transferring technology through laboratory twinning between the developed and the developing countries. Importantly for developing countries, the benefit of molecular methods as tools is the capability for a differential diagnosis of human diseases that present with similar clinical symptoms. Antemortem testing for human rabies is now possible using molecular techniques. These barriers are not insurmountable and it is our expectation that if such tests are accepted and implemented where they are most needed, they will provide substantial improvements for rabies diagnosis and surveillance. The advent of molecular biology and new technological initiatives that combine advances in biology with other disciplines will support the development of techniques capable of high throughput testing with a low turnaround time for rabies diagnosis