427 research outputs found

    Die Wirtschaftskrise Argentiniens 2001

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    Während der Wirtschaftskrise 2001 war die Zivilbevölkerung Argentiniens gezwungen, sich selbst zu organisieren, um ihr Existenzniveau zu erhalten und die staatliche Handlungsunfähigkeit auszugleichen sowie die ökonomisch prekäre Lage zu überwinden. Die verschiedenen Aktionen und sozialen Bewegungen, wie die Trueques, Asambleas, Fábricas Recuperadas, Piqueteros und Cartoneros wurden in dieser Arbeit analysiert.During the economic crisis of 2001, the Argentine civil population was forced to organize themselves to maintain their level of existence, to equilibrate the incapacitation of the state, and to amend the poor economic situation. The different actions and social movements, such as the Trueques, Asambleas, Fábricas Recuperadas, Piqueteros and Cartoneros were analized

    Duration and frequency of non‐flow periods affect the abundance and diversity of stream meiofauna

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    Majdi N, Colls M, Weiss L, Acuña V, Sabater S, Traunspurger W. Duration and frequency of non‐flow periods affect the abundance and diversity of stream meiofauna. Freshwater Biology. 2020;65(11):1906-1922.Abstract Intermittent streams (IS) comprise a large proportion of the drainage network in many parts of the world. The non‐flow period of IS are known to impact stream biota because aquatic habitats dry out. However, less well understood are the relative effects of the temporal component of these drying events including their duration and frequency. Here, we characterised effects of temporal component of drying events on abundant and species‐rich meiofauna. The effects were assessed in 22 streams in the north‐eastern Iberian Peninsula. The duration and frequency of non‐flow events was characterized over a period of 250 days prior to sampling the sediment‐dwelling meiofauna in riffle zones that completely dried out. Overall, meiofauna abundances were amongst the highest ever reported for streambeds. Most meiofaunal taxa correlated positively with the frequency of drying events and correlated positively with the length of dry periods recorded shortly before sampling, suggesting that the community was able to recover quickly. Tardigrades were the only group to correlate positively with the longest dry periods, suggesting that they had the best resilience capabilities in streams that had experienced the longest droughts. On average, nematodes made up half of the meiofauna. We identified a total of 113 different nematode species. The nematode community was more taxonomically diverse in IS, with a smaller proportion of bacterivores and a higher proportion of fungivore species such as Filenchus vulgaris. Thereby resembling the trophic structure commonly observed in soil ecosystems. Our results show that most meiofauna were positively influenced by drying disturbance, that is being able to quickly recover after them. This suggests outstanding resilience capabilities, and points out meiofaunal organisms as key players for kick‐starting stream food webs and functions once flow returns

    Technologie mobilne jako nośnik zmiany – w opinii nauczycieli z czterech krajów europejskich

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    Sylwia Galanciak, Miriam Judge, Anna Weiss, Technologie mobilne jako nośnik zmiany – w opinii nauczycieli z czterech krajów europejskich [Mobile technologies as a carrier of change – in the opinion of teachers from four European countries]. Interdyscyplinarne Konteksty Pedagogiki Specjalnej, nr 23, Poznań 2018. Pp. 203-220. Adam Mickiewicz University Press. ISSN 2300-391X. DOI: https://doi.org/10.14746/ikps.2018.23.12 The article presents partial results of qualitative research conducted among 83 respondents (28 teachers and 55 students) from four European countries, using tablets to work at school. The aim of the research was to recognize the scope of application of mobile technologies by teachers and students and also their opinions on the usefulness of these technologies as a support in the process of education. An image of teachers and students, who realistically assess the advantages and disadvantages of tablets, and who redefine their role in the educational process, emerges from the individual interviews and focus conversations.Sylwia Galanciak, Miriam Judge, Anna Weiss, Technologie mobilne jako nośnik zmiany – w opinii nauczycieli z czterech krajów europejskich [Mobile technologies as a carrier of change – in the opinion of teachers from four European countries]. Interdyscyplinarne Konteksty Pedagogiki Specjalnej, nr 23, Poznań 2018. Pp. 203-220. Adam Mickiewicz University Press. ISSN 2300-391X. DOI: https://doi.org/10.14746/ikps.2018.23.12 The article presents partial results of qualitative research conducted among 83 respondents (28 teachers and 55 students) from four European countries, using tablets to work at school. The aim of the research was to recognize the scope of application of mobile technologies by teachers and students and also their opinions on the usefulness of these technologies as a support in the process of education. An image of teachers and students, who realistically assess the advantages and disadvantages of tablets, and who redefine their role in the educational process, emerges from the individual interviews and focus conversations

    Obstetric risk in pregnancy interacts with hair cortisone levels to reduce gestational length

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    Background: Maternal psychological stress has been linked to preterm birth. However, the dierential contribution of psychological stress versus stress hormones is not clear. Studies focus primarily on perceived stress and cortisol, with few assessing its inter-convertible hormone cortisone. Furthermore, little is known about the potential moderating roles of obstetric risk and fetal sex in the relationship between maternal stress and gestational length. This gap in knowledge is particularly evident for rural women who typically experience chronic multiple stressors during pregnancy. We explored the relationship of hormonal and psychological stress to gestational length and the eects of obstetric risks and fetal sex on this relationship among Kenyan pregnant women. Methods: The sample included 130 women recruited between 22 to 28 weeks gestation. They completed a clinical and sociodemographic questionnaire together with the Perceived Stress Scale and provided a hair sample for cortisol and cortisone assay. Women underwent an ultrasound to assess weeks of gestation. At delivery, their pregnancy-related health problems were identified using information extracted from medical records to compile each woman’s number of pregnancy risks on the Obstetric Medical Risk Index (OMRI). Results: Perceived stress and hair cortisol were not significant predictors of gestational length. However, a greater number of obstetric risks on the OMRI was associated with shorter gestational length. This eect was further explained by the interaction between obstetric risk and hair cortisone (B = 0.709, p = 0.02). Hair cortisone levels of mothers who had a shorter gestation were significantly higher in mothers with 2 or more risks on the OMRI but not among mothers with only one or no risks (t = 2.39, p = 0.02). Fetal sex had no relationship to gestational length and also had no moderating effect on the relationship between any stress-related metric and gestational length. Conclusion: Cortisone levels may increase in anticipation of shorter gestation as a compensatory response to increased obstetric risk. Elevated cortisone may be a more sensitive marker of risk for early delivery than cortisol or psychological stress, with salience for both the male and female fetus

    Current Research of the Leiden-Turin Archaeological Mission in Saqqara. A Preliminary Report on the 2018 Season

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    In 2015, the Museo Egizio in Turin joined the Leiden expedition to Saqqara, in the area south of the Unas causeway. This report presents the expedition’s new approach as well as some first results of this new cooperation. In the 2018 season, the Leiden-Turin expedition worked in the northern sector of its concession, covering an area of ca. 250 sqm just north of the tomb of Maya. Here Late Antique layers overlie a wind-blown deposit containing some simple burials and numerous “embalmers’ caches”, some of which yielded marl clay cups with hieratic labels. An overview of both the pottery and the human remains found during this season is provided in the present report. Below the wind-blown deposit is a level with Ramesside funerary chapels and shafts. One of them has a remarkable decoration including six small-format figures carved in high relief in the middle of its back wall. The shaft of another chapel was also excavated, revealing several plundered chambers which yielded only scanty finds. A large mud-brick wall exposed during the previous season turned out to belong to the outer wall and pylon entrance of a monumental tomb, whose owner’s name has not been found yet. A photogrammetric survey by a team of the Politecnico di Milano yielded a 3D model of the dig (included in the web version of this report), as well as several 3D models of the monumental tombs (completed or in the making). During the season, conservation work was carried out on several tombs and on the newly discovered Ramesside chapel

    Aneurysmal Subarachnoid Hemorrhage in Hospitalized Patients on Anticoagulants—A Two Center Matched Case-Control Study

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    Objective—Direct oral anticoagulants (DOAC) are replacing vitamin K antagonists (VKA) for the prevention of ischemic stroke and venous thromboembolism. We set out to assess the effect of prior treatment with DOAC and VKA in patients with aneurysmal subarachnoid hemorrhage (SAH). Methods—Consecutive SAH patients treated at two (Aachen, Germany and Helsinki, Finland) university hospitals were considered for inclusion. To assess the association between anticoagulant treatments on SAH severity measure by modified Fisher grading (mFisher) and outcome as measured by the Glasgow outcome scale (GOS, 6 months), DOAC- and VKA-treated patients were compared against age- and sex-matched SAH controls without anticoagulants. Results—During the inclusion timeframes, 964 SAH patients were treated in both centers. At the time point of aneurysm rupture, nine patients (0.93%) were on DOAC treatment, and 15 (1.6%) patients were on VKA. These were matched to 34 and 55 SAH age- and sex-matched controls, re-spectively. Overall, 55.6% of DOAC-treated patients suffered poor-grade (WFNS4–5) SAH compared to 38.2% among their respective controls (p = 0.35); 53.3% of patients on VKA suffered poor-grade SAH compared to 36.4% in their respective controls (p = 0.23). Neither treatment with DOAC (aOR 2.70, 95%CI 0.30 to 24.23; p = 0.38), nor VKA (aOR 2.78, 95%CI 0.63 to 12.23; p = 0.18) were inde-pendently associated with unfavorable outcome (GOS1–3) after 12 months. Conclusions—Iatrogenic coagulopathy caused by DOAC or VKA was not associated with more severe radiological or clinical subarachnoid hemorrhage or worse clinical outcome in hospitalized SAH patients

    A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition

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    The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodies. We immunized llamas with gp41-MPER proteoliposomes and selected a MPER-specific single chain antibody (VHH), 2H10, whose epitope overlaps with that of mAb 2F5. Bi-2H10, a bivalent form of 2H10, which displayed an approximately 20-fold increased affinity compared to the monovalent 2H10, neutralized various sensitive and resistant HIV-1 strains, as well as SHIV strains in TZM-bl cells. X-ray and NMR analyses combined with mutagenesis and modeling revealed that 2H10 recognizes its gp41 epitope in a helical conformation. Notably, tryptophan 100 at the tip of the long CDR3 is not required for gp41 interaction but essential for neutralization. Thus bi-2H10 is an anti-MPER antibody generated by immunization that requires hydrophobic CDR3 determinants in addition to epitope recognition for neutralization similar to the mode of neutralization employed by mAbs 2F5 and 4E10
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