Power scaling rules for charmonia production and HQEFT

We discuss the power scaling rules along the lines of a complete Heavy Quark Effective Field Theory (HQEFT) for the description of heavy quarkonium production through a color-octet mechanism. To this end, we firstly derive a tree-level heavy quark effective Lagrangian keeping both particle-antiparticle mixed sectors allowing for heavy quark-antiquark pair annihilation and creation, but describing only low-energy modes around the heavy quark mass. Then we show the consistency of using HQEFT fields in constructing four-fermion local operators a la NRQCD, to be identified with standard color-octet matrix elements. We analyze some numerical values extracted from charmonia production by different authors and their hierarchy in the light of HQEFT.Comment: LaTeX, 19 pages, 3 EPS figure

Literature review

Recognising that every PhD is different, the authors discuss three ways to find one’s voice when constructing a literature review. Ryan adopted an interdisciplinary stance, where he compared and contrasted the meanings of key concepts across a range of academic disciplines before arriving at his own definitions. By contrast, Wang began by reading deeply within the specific topic of her thesis, and attempting to find her own critical voice. Lin suggests a reflexive approach in which the candidate and their supervisors share and enrich each other’s cultural capital; this should lead to the candidate finding their own voice and eventually becoming a legitimate participant in the academic community of practice

Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis.

Epidermal growth factor receptor (EGFR)-mutation-positive non-smallcell lung cancer (NSCLC) is incurable, despite high rates of response to EGFR tyrosine kinase inhibitors (TKIs). We investigated receptor tyrosine kinases (RTKs), Src family kinases and focal adhesion kinase (FAK) as genetic modifiers of innate resistance in EGFR-mutation-positive NSCLC. We performed gene expression analysis in two cohorts (Cohort 1 and Cohort 2) of EGFR-mutation-positive NSCLC patients treated with EGFR TKI. We evaluated the efficacy of gefitinib or osimertinib with the Src/FAK/Janus kinase 2 (JAK2) inhibitor, TPX0005 in vitro and in vivo. In Cohort 1, CUB domain-containing protein-1 (CDCP1) was an independent negative prognostic factor for progression-free survival (hazard ratio of 1.79, p=0.0407) and overall survival (hazard ratio of 2.23, p=0.0192). A two-gene model based on AXL and CDCP1 expression was strongly associated with the clinical outcome to EGFR TKIs, in both cohorts of patients. Our preclinical experiments revealed that several RTKs and non-RTKs, were up-regulated at baseline or after treatment with gefitinib or osimertinib. TPX-0005 plus EGFR TKI suppressed expression and activation of RTKs and downstream signaling intermediates. Co-expression of CDCP1 and AXL is often observed in EGFR-mutation-positive tumors, limiting the efficacy of EGFR TKIs. Co-treatment with EGFR TKI and TPX-0005 warrants testing

A Tale of Three Signatures: practical attack of ECDSA with wNAF

One way of attacking ECDSA with wNAF implementation for the scalar multiplication is to perform a side-channel analysis to collect information, then use a lattice based method to recover the secret key. In this paper, we reinvestigate the construction of the lattice used in one of these methods, the Extended Hidden Number Problem (EHNP). We find the secret key with only 3 signatures, thus reaching the theoretical bound given by Fan, Wang and Cheng, whereas best previous methods required at least 4 signatures in practice. Our attack is more efficient than previous attacks, in particular compared to times reported by Fan et al. at CCS 2016 and for most cases, has better probability of success. To obtain such results, we perform a detailed analysis of the parameters used in the attack and introduce a preprocessing method which reduces by a factor up to 7 the overall time to recover the secret key for some parameters. We perform an error resilience analysis which has never been done before in the setup of EHNP. Our construction is still able to find the secret key with a small amount of erroneous traces, up to 2% of false digits, and 4% with a specific type of error. We also investigate Coppersmith's methods as a potential alternative to EHNP and explain why, to the best of our knowledge, EHNP goes beyond the limitations of Coppersmith's methods

A non-uniform predictor-observer for a networked control system

The final publication is available at Springer via http://dx.doi.org/10.1007/s12555-011-0621-5This paper presents a Non-Uniform Predictor-Observer (NUPO) based control approach in order to deal with two of the main problems related to Networked Control Systems (NCS) or Sensor Networks (SN): time-varying delays and packet loss. In addition, if these delays are longer than the sampling period, the packet disordering phenomenon can appear. Due to these issues, a (scarce) nonuniform, delayed measurement signal could be received by the controller. But including the NUPO proposal in the control system, the delay will be compensated by the prediction stage, and the nonavailable data will be reconstructed by the observer stage. So, a delay-free, uniformly sampled controller design can be adopted. To ensure stability, the predictor must satisfy a feasibility problem based on a time-varying delay-dependent condition expressed in terms of Linear Matrix Inequalities (LMI). Some aspects like the relation between network delay and robustness/performance trade-off are empirically studied. A simulation example shows the benefits (robustness and control performance improvement) of the NUPO approach by comparison to another similar proposal. © ICROS, KIEE and Springer 2011.This work was supported by the Spanish Ministerio de Ciencia y Tecnologia Projects DPI2008-06737-C02-01 and DPI2009-14744-C03-03, by Generalitat Valenciana Project GV/2010/018, by Universidad Politecnica de Valencia Project PAID06-08.Cuenca Lacruz, ÁM.; García Gil, PJ.; Albertos Pérez, P.; Salt Llobregat, JJ. (2011). A non-uniform predictor-observer for a networked control system. International Journal of Control, Automation and Systems. 9(6):1194-1202. doi:10.1007/s12555-011-0621-5S1194120296K. Ogata, Discrete-time Control Systems, Prentice-Hall, Inc., Upper Saddle River, NJ, USA, 1987.Y. Tipsuwan and M. Chow, “Control methodologies in networked control systems,” Control Eng. Practice, vol. 11, no. 10, pp. 1099–1111, 2003.T. Jia, Y. Niu, and X. Wang, “H ∞ control for networked systems with data packet dropout,” Int. J. Control, Autom., and Syst., vol. 8, no. 2, pp. 198–203, 2010.Y. Wang and G. Yang, “Robust H ∞ model reference tracking control for networked control systems with communication constraints,” Int. J. Control, Autom., and Syst., vol. 7, no. 6, pp. 992–1000, 2009.H. Gao and T. Chen, “Network-based H ∞ output tracking control,” IEEE Trans. Autom. Control, vol. 53, no. 3, pp. 655–667, 2008.H. Karimi, “Robust H ∞ filter design for uncertain linear systems over network with network-induced delays and output quantization,” Modeling, Identification and Control, vol. 30, no. 1, pp. 27–37, 2009.H. R. Karimi, “Delay-range-dependent linear matrix inequality approach to quantized H ∞ control of linear systems with network-induced delays and norm-bounded uncertainties,” Proc. of the Inst. of Mech. Eng., Part I: J. of Syst. and Control Eng., vol. 224, no. 6, pp. 689–700, 2010.K. Lee, S. Lee, and M. Lee, “Remote fuzzy logic control of networked control system via Profibus-DP,” IEEE Trans. Ind. Electron., vol. 50, no. 4, pp. 784–792, 2003.Y. Tipsuwan and M.-Y. Chow, “Gain scheduler middleware: a methodology to enable existing controllers for networked control and teleoperationpart I: networked Control,” IEEE Trans. on Industrial Electronics, vol. 51, no. 6, pp. 1218–1227, December 2004.A. Sala, A. Cuenca, and J. Salt, “A retunable PID multi-rate controller for a networked control system,” Inform. Sci., vol. 179, no. 14, pp. 2390–2402, June 2009.A. Cuenca, J. Salt, V. Casanova, and R. Piza, “An approach based on an adaptive multi-rate Smith predictor and gain scheduling for a networked control system: implementation over Profibus-DP,” Int. J. Control, Autom., and Syst., vol. 8, no. 2, pp. 473–481, April 2010.A. Cuenca, J. Salt, A. Sala, and R. Piza, “A delay-dependent dual-rate PID controller over an Ethernet network,” IEEE Trans. Ind. Informat., vol. 7, no. 1, pp. 18–29, Feb. 2011.Y. Tian and D. Levy, “Compensation for control packet dropout in networked control systems,” Inform. Sci., vol. 178, no. 5, pp. 1263–1278, 2008.Y. Zhao, G. Liu, and D. Rees, “Modeling and stabilization of continuous-time packet-based networked control systems.” IEEE Trans. Syst., Man, Cybern. B, vol. 39, no. 6, pp. 1646–1652, Dec. 2009.X. Zhao, S. Fei, and C. Sun, “Impulsive controller design for singular networked control systems with packet dropouts,” Int. J. Control, Autom., and Syst., vol. 7, no. 6, pp. 1020–1025, 2009.H. Gao and T. Chen, “H ∞ estimation for uncertain systems with limited communication capacity,” IEEE Trans. Autom. Control, vol. 52, no. 11, pp. 2070–2084, 2007.S. Oh, L. Schenato, P. Chen, and S. Sastry, “Tracking and coordination of multiple agents using sensor networks: System design, algorithms and experiments,” Proc. of the IEEE, vol. 95, no. 1, pp. 234–254, 2007.M. Moayedi, Y. Foo, and Y. Soh, “Optimal and suboptimal minimum-variance filtering in networked systems with mixed uncertainties of random sensor delays, packet dropouts and missing measurements,” Int. J. Control, Autom., and Syst., vol. 8, no. 6, pp. 1179–1188, 2010.W. Zhang, M. Branicky, and S. Phillips, “Stability of networked control systems,” IEEE Control Syst. Mag., vol. 21, no. 1, pp. 84–99, 2001.J. Hespanha, P. Naghshtabrizi, and Y. Xu, “A survey of recent results in networked control systems,” Proc. of the IEEE, vol. 95, no. 1, pp. 138–162, 2007.J. Baillieul and P. Antsaklis, “Control and communication challenges in networked real-time systems,” Proc. of the IEEE, vol. 95, no. 1, pp. 9–28, 2007.P. Garcia, P. Castillo, R. Lozano, and P. Albertos, “Robustness with respect to delay uncertainties of a predictor-observer based discrete-time controller,” Proc. of the 45th IEEE Conf. on Decision and Control, pp. 199–204, 2006.C. Lien, “Robust observer-based control of systems with state perturbations via LMI approach,” IEEE Trans. Autom. Control, vol. 49, no. 8, pp. 1365–1370, 2004.A. Sala, “Computer control under time-varying sampling period: an LMI gridding approach,” Automatica, vol. 41, no. 12, pp. 2077–2082, Dec. 2005.J. Li, Q. Zhang, Y. Wang, and M. Cai, “H ∞ control of networked control systems with packet disordering,” IET Control Theory Appl., vol. 3, no. 11, pp. 1463–1475, March 2009.Y. Zhao, G. Liu, and D. Rees, “Improved predictive control approach to networked control systems,” IET Control Theory Appl., vol. 2, no. 8, pp. 675–681, Aug. 2008.K. Astrom, “Event based control,” Analysis and Design of Nonlinear Control Systems, pp. 127–147, 2007.A. Cuenca, P. García, K. Arzén, and P. 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Symp. on Mathematical Theory of Networks and Systems, pp. 2163–2170, 2006.D. Davison and E. Hwang, “Automating radiotherapy cancer treatment: use of multirate observer-based control,” Proc. of American Control Conf., vol. 2, pp. 1194–1199, 2003

Understanding Crowd-Powered Search Groups: A Social Network Perspective

Background: Crowd-powered search is a new form of search and problem solving scheme that involves collaboration among a potentially large number of voluntary Web users. Human flesh search (HFS), a particular form of crowd-powered search originated in China, has seen tremendous growth since its inception in 2001. HFS presents a valuable test-bed for scientists to validate existing and new theories in social computing, sociology, behavioral sciences, and so forth. Methodology: In this research, we construct an aggregated HFS group, consisting of the participants and their relationships in a comprehensive set of identified HFS episodes. We study the topological properties and the evolution of the aggregated network and different sub-groups in the network. We also identify the key HFS participants according to a variety of measures. Conclusions: We found that, as compared with other online social networks, HFS participant network shares the power-law degree distribution and small-world property, but with a looser and more distributed organizational structure, leading to the diversity, decentralization, and independence of HFS participants. In addition, the HFS group has been becoming increasingly decentralized. The comparisons of different HFS sub-groups reveal that HFS participants collaborated more often when they conducted the searches in local platforms or the searches requiring a certain level of professional knowledge background. On the contrary, HFS participants did not collaborate much when they performed the search tas

Galaxy and Mass Assembly (GAMA): A WISE study of the activity of emission-line systems in G23

We present a detailed study of emission-line systems in the Galaxy And Mass Assembly (GAMA) G23 region, making use of Wide-field Infrared Survey Explorer (WISE) photometry that includes carefully measured resolved sources. After applying several cuts to the initial catalog of. 41,000 galaxies, we extract a sample of 9809 galaxies. We then compare the spectral diagnostic Baldwin, Philips & Terlevich (BPT) classification of 1154 emission-line galaxies (38% resolved in W1) to their location in the WISE color-color diagram, leading to the creation of a new zone for mid-infrared warm galaxies located 2μm above the star-forming sequence, below the standard WISE active galactic nucleus (AGN) region. We find that the BPT and WISE diagrams agree on the classification for 85% and 8% of the galaxies as non-AGN (star-forming = SF) and AGN, respectively, and disagree on. 7% of the entire classified sample. Thirty-nine percent of the AGNs (all types) are broad-line systems for which the [N II] and [Hα] fluxes can barely be disentangled, giving in most cases spurious [N II]/[Hα] flux ratios. However, several optical AGNs appear to be completely consistent with SF in WISE. We argue that these could be low-power AGNs, or systems whose hosts dominate the IR emission. Alternatively, given the sometimes high [O III] luminosity in these galaxies, the emission lines may be generated by shocks coming from super-winds associated with SF rather than AGN activity. Based on our findings, we have created a new diagnostic: [W1 - W2] versus [N II]/[Hα], which has the virtue of separating SF from AGNs and high-excitation sources. It classifies 3 to ∼5 times more galaxies than the classic BPT

Resonant Andreev reflections in superconductor-carbon-nanotube devices

Resonant Andreev reflection through superconductor-carbon-nanotube devices was investigated theoretically with a focus on the superconducting proximity effect. Consistent with a recent experiment, we find that for high transparency devices on-resonance, the Andreev current is characterized by a large value and a resistance dip; low-transparency off-resonance devices give the opposite result. We also give evidence that the observed low-temperature transport anomaly may be a natural result of Andreev reflection process

The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation

Background: The regulatory subunit (R) of cAMP-dependent protein kinase (PKA) is a modular flexible protein that responds with large conformational changes to the binding of the effector cAMP. Considering its highly dynamic nature, the protein is rather stable. We studied the thermal denaturation of full-length RIα and a truncated RIα(92-381) that contains the tandem cyclic nucleotide binding (CNB) domains A and B. Methodology/Principal Findings: As revealed by circular dichroism (CD) and differential scanning calorimetry, both RIα proteins contain significant residual structure in the heat-denatured state. As evidenced by CD, the predominantly α-helical spectrum at 25°C with double negative peaks at 209 and 222 nm changes to a spectrum with a single negative peak at 212-216 nm, characteristic of β-structure. A similar α→β transition occurs at higher temperature in the presence of cAMP. Thioflavin T fluorescence and atomic force microscopy studies support the notion that the structural transition is associated with cross-β-intermolecular aggregation and formation of non-fibrillar oligomers. Conclusions/Significance: Thermal denaturation of RIα leads to partial loss of native packing with exposure of aggregation-prone motifs, such as the B' helices in the phosphate-binding cassettes of both CNB domains. The topology of the β-sandwiches in these domains favors inter-molecular β-aggregation, which is suppressed in the ligand-bound states of RIα under physiological conditions. Moreover, our results reveal that the CNB domains persist as structural cores through heat-denaturation. © 2011 Dao et al

Galaxy and Mass Assembly (GAMA): A WISE Study of the Activity of Emission-line Systems in G23

We present a detailed study of emission-line systems in the GAMA G23 region, making use of WISE photometry that includes carefully measured resolved sources. After applying several cuts to the initial catalogue of ∼41,000 galaxies, we extract a sample of 9,809 galaxies. We then compare the spectral diagnostic (BPT) classification of 1154 emission-line galaxies (38% resolved in W1) to their location in the WISE colour-colour diagram, leading to the creation of a new zone for mid-infrared “warm” galaxies located 2σ above the star-forming sequence, below the standard WISE AGN region. We find that the BPT and WISE diagrams agree on the classification for 85% and 8% of the galaxies as non-AGN (star forming = SF) and AGN, respectively, and disagree on ∼7% of the entire classified sample. 39% of the AGN (all types) are broad-line systems for which the [N ii] and [Hα] fluxes can barely be disentangled, giving in most cases spurious [N ii]/[Hα] flux ratios. However, several optical AGN appear to be completely consistent with SF in WISE. We argue that these could be low power AGN, or systems whose hosts dominate the IR emission. Alternatively, given the sometimes high [O iii] luminosity in these galaxies, the emission lines may be generated by shocks coming from super-winds associated with SF rather than the AGN activity. Based on our findings, we have created a new diagnostic: [W1-W2] vs [N ii]/[Hα], which has the virtue of separating SF from AGN and high-excitation sources. It classifies 3∼5 times more galaxies than the classic BPT