1,202 research outputs found

    Hardening mechanism of commercially pure Mg processed by high pressure torsion at room temperature

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    Coarse-grained Mg in the as-cast condition and fine-grained Mg in the extruded condition were processed by high pressure torsion (HPT) at room temperature for up to 16 turns. Microstructure observation and texture analysis indicate that to fulfil the Von Mises criterion, the non-basal slip is activated in the as-cast Mg and tension twinning is activated in the as-extruded Mg. Although the deformation mechanism is different in the as-cast Mg and the as-extruded Mg during HPT, their hardening evolutions are similar, i.e. after 1/8 turn of HPT, microhardness of the as-cast Mg and the extruded Mg both show a significant increase and further HPT processing does not significantly further increase the microhardness. Texture strengthening can explain the rapid hardening. Hardness anisotropy and texture data results suggest that texture strengthening plays an important role for both types of samples. Texture strengthening weakens with decreasing grain size

    Glycolytic Reprogramming Through PCK2 Regulates Tumor Initiation of Prostate Cancer Cells

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    Tumor-initiating cells (TICs) play important roles in tumor progression and metastasis. Identifying the factors regulating TICs may open new avenues in cancer therapy. Here, we show that TIC-enriched prostate cancer cell clones use more glucose and secrete more lactate than TIC-low clones. We determined that elevated levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabolic switch and the maintenance of TICs in prostate cancer. Information from prostate cancer patient databases revealed that higher PCK2 levels correlated with more aggressive tumors and lower survival rates. PCK2 knockdown resulted in low TIC numbers, increased cytosolic acetyl-CoA and cellular protein acetylation. Our data suggest PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. Thus, PCK2 is a potential therapeutic target for aggressive prostate tumors

    Development of a multiplex event-specific PCR assay for detection of genetically modified rice

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    Global rice supplies have been found contaminated with unapproved varieties of genetically modified (GM) rice in recent years, which has led to product recalls in several of countries. Faster and more effective detection of GM contamination can prevent adulterated food, feed and seed from being consumed and grown, minimize the potential environmental, health or economic damage. In this study, a simple, reliable and cost-effective multiplex polymerase chain reaction (PCR) assay for identifying genetic modifications of TT51-1, Kemingdao1 (KMD1) and Kefeng6 (KF6) rice was developed by using the event-specific fragment. The limit of detection (LOD) for each event in the multiplex PCR is approximately 0.1%. Developed multiplex PCR assays can provide a rapid and simultaneous detection of GM rice

    Nonlinear optical interactions in silicon waveguides

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    The strong nonlinear response of silicon photonic nanowire waveguides allows for the integration of nonlinear optical functions on a chip. However, the detrimental nonlinear optical absorption in silicon at telecom wavelengths limits the efficiency of many such experiments. In this review, several approaches are proposed and demonstrated to overcome this fundamental issue. By using the proposed methods, we demonstrate amongst others supercontinuum generation, frequency comb generation, a parametric optical amplifier, and a parametric optical oscillator

    Interference between the halves of a double-well trap containing a Bose-Einstein condensate

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    Interference between the halves of a double-well trap containing a Bose-Einstein condensate is studied. It is found that when the atoms in the two wells are initially in the coherent state, the intensity exhibits collapses and revivals, but it does not for the initial Fock states. Whether the initial states are in the coherent states or in a Fock states, the fidelity time has nothing to do with collision. We point out that interference and its fidelity can be adjusted experimentally by properly preparing the number and initial states of the system.Comment: 10 pages, 3 figures, accepted by Phy. rev.

    Non-Markovian dynamics in a spin star system: The failure of thermalization

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    In most cases, a small system weakly interacting with a thermal bath will finally reach the thermal state with the temperature of the bath. We show that this intuitive picture is not always true by a spin star model where non-Markov effect predominates in the whole dynamical process. The spin star system consists a central spin homogeneously interacting with an ensemble of identical noninteracting spins. We find that the correlation time of the bath is infinite, which implies that the bath has a perfect memory, and that the dynamical evolution of the central spin must be non- Markovian. A direct consequence is that the final state of the central spin is not the thermal state equilibrium with the bath, but a steady state which depends on its initial state.Comment: 8 page

    Magnetic rogue wave in a perpendicular anisotropic ferromagnetic nanowire with spin-transfer torque

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    We present the current controlled motion of dynamic soliton embedded in spin wave background in ferromagnetic nanowire. With the stronger breather character we get the novel magnetic rogue wave and clarify its formation mechanism. The generation of magnetic rogue wave is mainly arose from the accumulation of energy and magnons toward to its central part. We also observe that the spin-polarized current can control the exchange rate of magnons between envelope soliton and background, and the critical current condition is obtained analytically. Even more interesting is that the spin-transfer torque plays the completely opposite role for the cases of below and above the critical value.Comment: 5 figure

    Influence of the detector's temperature on the quantum Zeno effect

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    In this paper we study the quantum Zeno effect using the irreversible model of the measurement. The detector is modeled as a harmonic oscillator interacting with the environment. The oscillator is subjected to the force, proportional to the energy of the measured system. We use the Lindblad-type master equation to model the interaction with the environment. The influence of the detector's temperature on the quantum Zeno effect is obtained. It is shown that the quantum Zeno effect becomes stronger (the jump probability decreases) when the detector's temperature increases

    Boosting Reversibility and Stability of Zn Anodes via Manipulation of Electrolyte Structure and Interface with Addition of Trace Organic Molecules

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    Published online: August 17, 2022The practical application of aqueous zinc-ion batteries (AZIBs) is significantly limited by poor reversibility and stability of the Zn anode. Here, the first time addition of trace organic gamma butyrolactone (GBL) is reported to a typical ZnSO₄ electrolyte to controllably manipulate the electrolyte structure and interface. Judiciously combined experimental characterization and theoretical computation confirm that the GBL additive weakens the bonding strength between Zn²⁺ ion and solvated H₂O and rearranges the “Zn²⁺−H₂O−SO₄²– GBL” bonding network to reduce water activity and suppress corrosion and side products. The GBL molecules preferentially absorb on the surface of the Zn anode to give a uniform and compact Zn deposition. As a result, the Zn anode is boosted to run over 3105 cycles (6210 h) with average Coulombic efficiency of 99.93% under 1 mA cm−² and 1 mAh cm−², and exhibit stable cycling for 1170 h under harsh testing conditions of 10 mA cm−² and 10 mAh cm−². Additionally, the Zn–MnO₂ full cells using the ZnSO₄–GBL electrolyte exhibit a high capacity of 287 mAh g−¹ at 0.5 A g−¹ and good capacity retention of 87% following 400 cycles. These findings will be of immediate benefit to design low cost AZIBs for clean energy storage.Haiji Huang, Dongmei Xie, Jiachang Zhao, Pinhua Rao, Won Mook Choi, Kenneth Davey, and Jianfeng Ma
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