2,388 research outputs found

    Absorbing systematic effects to obtain a better background model in a search for new physics

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    This paper presents a novel approach to estimate the Standard Model backgrounds based on modifying Monte Carlo predictions within their systematic uncertainties. The improved background model is obtained by altering the original predictions with successively more complex correction functions in signal-free control selections. Statistical tests indicate when sufficient compatibility with data is reached. In this way, systematic effects are absorbed into the new background model. The same correction is then applied on the Monte Carlo prediction in the signal region. Comparing this method to other background estimation techniques shows improvements with respect to statistical and systematical uncertainties. The proposed method can also be applied in other fields beyond high energy physics

    Quantitative study of valence and configuration interaction parameters of the Kondo semiconductors CeM2Al10 (M = Ru, Os and Fe) by means of bulk-sensitive hard x-ray photoelectron spectroscopy

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    The occupancy of the 4f^n contributions in the Kondo semiconductors CeM2Al10(M = Ru, Os and Fe) has been quantitatively determined by means of bulk-sensitive hard x-ray photoelectron spectroscopy (HAXPES) on the Ce 3d core levels. Combining a configuration interaction scheme with full multiplet calculations allowed to accurately describe the HAXPES data despite the presence of strong plasmon excitations in the spectra. The configuration interaction parameters obtained from this analysis -- in particular the hybridization strength V_eff and the effective f binding energy Delta_f -- indicate a slightly stronger exchange interaction in CeOs2Al10 compared to CeRu2Al10, and a significant increase in CeFe2Al10. This verifies the coexistence of a substantial amount of Kondo screening with magnetic order and places the entire CeM2Al10 family in the region of strong exchange interactions.Comment: 9 pages, 4 figures, submitted to Physical Review

    CeRu4_4Sn6_6: a strongly correlated material with nontrivial topology

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    Topological insulators form a novel state of matter that provides new opportunities to create unique quantum phenomena. While the materials used so far are based on semiconductors, recent theoretical studies predict that also strongly correlated systems can show non-trivial topological properties, thereby allowing even the emergence of surface phenomena that are not possible with topological band insulators. From a practical point of view, it is also expected that strong correlations will reduce the disturbing impact of defects or impurities, and at the same increase the Fermi velocities of the topological surface states. The challenge is now to discover such correlated materials. Here, using advanced x-ray spectroscopies in combination with band structure calculations, we infer that CeRu4_4Sn6_6 is a strongly correlated material with non-trivial topology.Comment: 10 pages, 6 figures, submitted to Scientific Report

    Optimal control theory for unitary transformations

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    The dynamics of a quantum system driven by an external field is well described by a unitary transformation generated by a time dependent Hamiltonian. The inverse problem of finding the field that generates a specific unitary transformation is the subject of study. The unitary transformation which can represent an algorithm in a quantum computation is imposed on a subset of quantum states embedded in a larger Hilbert space. Optimal control theory (OCT) is used to solve the inversion problem irrespective of the initial input state. A unified formalism, based on the Krotov method is developed leading to a new scheme. The schemes are compared for the inversion of a two-qubit Fourier transform using as registers the vibrational levels of the X1Σg+X^1\Sigma^+_g electronic state of Na2_2. Raman-like transitions through the A1Σu+A^1\Sigma^+_u electronic state induce the transitions. Light fields are found that are able to implement the Fourier transform within a picosecond time scale. Such fields can be obtained by pulse-shaping techniques of a femtosecond pulse. Out of the schemes studied the square modulus scheme converges fastest. A study of the implementation of the QQ qubit Fourier transform in the Na2_2 molecule was carried out for up to 5 qubits. The classical computation effort required to obtain the algorithm with a given fidelity is estimated to scale exponentially with the number of levels. The observed moderate scaling of the pulse intensity with the number of qubits in the transformation is rationalized.Comment: 32 pages, 6 figure

    Singlet magnetism in intermetallic UGa2_2 unveiled by inelastic x-ray scattering

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    Using high resolution tender-x-ray resonant inelastic scattering and hard-x-ray non-resonant inelastic scattering beyond the dipole limit we were able to detect electronic excitations in intermetallic UGa2_2 that are highly atomic in nature. Analysis of the spectral lineshape reveals that the local 5f25f^2 configuration characterizes the correlated nature of this ferromagnet. The orientation and directional dependence of the spectra indicate that the ground state is made of the Γ1\Gamma_1 singlet and/or Γ6\Gamma_6 doublet symmetry. With the ordered moment in the abab plane, we infer that the magnetism originates from the higher lying Γ6\Gamma_6 doublet being mixed with the Γ1\Gamma_1 singlet due to inter-site exchange, qualifying UGa2_2 to be a true quantum magnet. The ability to observe atomic excitations is crucial to resolve the on-going debate about the degree of localization versus itineracy in U intermetallics.Comment: 9 pages, 7 figure

    Spectroscopic evidence of Kondo-induced quasi-quartet in CeRh2_2As2_2

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    CeRh2_2As2_2 is a new multiphase superconductor with strong suggestions for an additional itinerant multipolar ordered phase. The modeling of the low temperature properties of this heavy fermion compound requires a quartet Ce3+^{3+} crystal-field ground state. Here we provide the evidence for the formation of such a quartet state using x-ray spectroscopy. Core-level photoelectron and x-ray absorption spectroscopy confirm the presence of Kondo hybridization in CeRh2_2As2_2. The temperature dependence of the linear dichroism unambiguously reveils the impact of Kondo physics for coupling the Kramer's doublets into an effective quasi-quartet. Non-resonant inelastic x-ray scattering data find that the Γ7|\Gamma_7^- \rangle state with its lobes along the 110 direction of the tetragonal structure (xyxy orientation) contributes most to the multi-orbital ground state of CeRh2_2As2_2.Comment: 8 pages, 7 figure

    Novel hepatoselective insulin analog

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    Cel pracy. Zbadanie, czy tyroksylowy analog insuliny z ograniczonym dostępem do receptora w tkankach obwodowych wykazuje względnie wybiórcze powinowactwo do wątroby u ludzi. MATERIAŁ i metody. Pięć zdrowych osób otrzymywało podskórnie Na B1L-thyroksyl-insulinę (B1-T4-Ins) lub insulinę NPH w przypadkowej kolejności. Posługując się metodą klamry euglikemicznej i rozcieńczania znacznika izotopowego([D-6,6-2H2] glukozy), badano kinetykę insuliny oraz jej względny wpływ na wątrobową produkcję i obwodowy wychwyt glukozy. Pobierano próbki krwi w celu oznaczenia całkowitego stężenia insuliny immunoreaktywnej (bądź jej analogu) oraz w celu określenia stopnia wiązania analogu insuliny z białkami krwi, który badano metodą chromatografii cieczowej. Wyniki. Po podskórnym podaniu B1-T4-Ins była dobrze tolerowana i szybko wchłaniana. Analog cechował się długim czasem półtrwania w surowicy oraz wysokim stopniem wiązania (ok. 86%) z białkami. Jego czas działania, mierzony czasem wlewu glukozy niezbędnym do utrzymania euglikemii, był podobny do czasu działania insuliny NPH. Wpływ analogu na wątrobową produkcję glukozy był podobny do wpływu insuliny NPH, co wskazuje na podobny stopień oddziaływania. Analog w mniejszym stopniu działał na obwodowy wychwyt insuliny w porównaniu z insuliną NPH (p = 0,025), nie wpływał na szybkość przemian metabolicznych glukozy oraz wykazywał zmniejszoną zdolność do hamowania lipolizy (p < 0,05). Wnioski. U osób zdrowych B1-T4-Ins po podaniu podskórnym jest dobrze tolerowana, szybko się wchłania i ma wysoki stopień związania z białkami krwi, co odpowiada za długi czas połowicznego zaniku w surowicy. Analog ten wydaje się bardziej wybiórczy w oddziaływaniu na komórki wątroby, a zatem potencjalnie ma bardziej fizjologiczny profil działania w porównaniu z dotychczas stosowanymi preparatami insuliny.OBJECTIVE. To test whether a thyroxyl-insulin analog with restricted access to receptor sites in peripheral tissues displays relative hepatoselectivity in humans. RESEARCH DESIGN AND METHODS. Five normal human subjects received a subcutaneous bolus injection of either N B1 L-thyroxyl-insulin (B1-T4-Ins) or NPH insulin in random order. Insulin kinetics, relative effects on hepatic glucose production, and peripheral glucose uptake were studied using euglycemic clamp and stable isotope [D-6,6-2H2]glucose) dilution techniques. Blood samples were taken for the determination of total immunoreactive insulin/analog concentrations and for liquid chromatography to assess the protein binding of the analog in the circulation. RESULTS. After subcutaneous administration, B1-T4-Ins was well tolerated and rapidly absorbed. The analog had a long serum half-life and was highly protein bound (~86%). Its duration of action, as judged by the duration of infusion of exogenous glucose to maintain euglycemia, was similar to that of NPH insulin. The effect of the analogs on hepatic glucose production was similar to that of NPH insulin, indicating equivalent hepatic potency. The analog demonstrated less effect on peripheral glucose uptake than NPH insulin (P = 0,025), had no effect on metabolic clearance rate of glucose, and exhibited a reduced capacity to inhibit lipolysis (P < 0,05). CONCLUSIONS. When injected subcutaneously into normal human subjects, B1-T4-Ins is well tolerated, quickly absorbed, and highly protein bound, resulting in a long plasma half-life. This analog appears to have a hepatoselective action, and, therefore, has the potential to provide more physiological insulin action than the insulin preparations currently used

    Measurement of the quasi-elastic axial vector mass in neutrino-oxygen interactions

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    The weak nucleon axial-vector form factor for quasi-elastic interactions is determined using neutrino interaction data from the K2K Scintillating Fiber detector in the neutrino beam at KEK. More than 12,000 events are analyzed, of which half are charged-current quasi-elastic interactions nu-mu n to mu- p occurring primarily in oxygen nuclei. We use a relativistic Fermi gas model for oxygen and assume the form factor is approximately a dipole with one parameter, the axial vector mass M_A, and fit to the shape of the distribution of the square of the momentum transfer from the nucleon to the nucleus. Our best fit result for M_A = 1.20 \pm 0.12 GeV. Furthermore, this analysis includes updated vector form factors from recent electron scattering experiments and a discussion of the effects of the nucleon momentum on the shape of the fitted distributions.Comment: 14 pages, 10 figures, 6 table

    Measurement of Branching Fraction and Dalitz Distribution for B0->D(*)+/- K0 pi-/+ Decays

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    We present measurements of the branching fractions for the three-body decays B0 -> D(*)-/+ K0 pi^+/-andtheirresonantsubmodes and their resonant submodes B0 -> D(*)-/+ K*+/- using a sample of approximately 88 million BBbar pairs collected by the BABAR detector at the PEP-II asymmetric energy storage ring. We measure: B(B0->D-/+ K0 pi+/-)=(4.9 +/- 0.7(stat) +/- 0.5 (syst)) 10^{-4} B(B0->D*-/+ K0 pi+/-)=(3.0 +/- 0.7(stat) +/- 0.3 (syst)) 10^{-4} B(B0->D-/+ K*+/-)=(4.6 +/- 0.6(stat) +/- 0.5 (syst)) 10^{-4} B(B0->D*-/+ K*+/-)=(3.2 +/- 0.6(stat) +/- 0.3 (syst)) 10^{-4} From these measurements we determine the fractions of resonant events to be : f(B0-> D-/+ K*+/-) = 0.63 +/- 0.08(stat) +/- 0.04(syst) f(B0-> D*-/+ K*+/-) = 0.72 +/- 0.14(stat) +/- 0.05(syst)Comment: 7 pages, 3 figures submitted to Phys. Rev. Let
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