Willingness to pay to protect cold water corals

There is increasing pressure to use currently untapped resources in the deep sea, raising questions regarding ecosystem service trade‐offs in these often unknown areas. We assessed the trade‐offs between protection of cold‐water coral reefs and economic activities, such as fisheries and petroleum extraction, through a survey of a representative sample of the populations of Norway and Ireland. Choice‐experiment surveys were conducted in workshop settings and through the internet. Both survey approaches provided some similar results, such as preferences for protection. Our cross‐country comparison showed the general public in Norway and Ireland was willing, despite possible conflict with extractive and consumptive economic activities in the deep sea, to protect cold‐water corals as habitat for fish. On average, people were willing to pay NKr 341 and NKr 424 for a small and large increase in protected areas respectively, and NKr 880 if the area is important habitat for fish, all else held equal. However, there was large variation across individuals and countries. Norwegian respondents valued pure existence of cold‐water corals more than the Irish respondents, and the latter were less willing to trade off industrial activities than the former. Nonetheless, the findings support conservation of cold‐water corals and more generally of ocean environments that provide habitat for fish, which the current deep sea governance systems are not adequately designed or sufficiently well‐structured to secure

Gaming motivation and well-being among Norwegian adult gamers: the role of gender and disability

IntroductionDigital gaming is a popular and often social activity, also among adults. However, we need more knowledge of the social dynamics of gaming and its potential benefits for one's well-being. The current study aimed to examine gaming motivation, time spent gaming, and gaming performed together with friends, family, or romantic partner and how these aspects relate to expanded social network and well-being among men and women with and without disability.MethodsRegular players of the popular game Fortnite Battle Royale (FBR; N = 278, 48.5% women, Mage = 32.38) completed an online questionnaire assessing their motivations for playing FBR (social motivation, achievement motivation, novelty motivation), time spent gaming, whom they usually play with, their psychological well-being, and FBR's impact on their life and social network. Differentiated statistical analyses on gender and disability were performed.Results and discussionThe results showed that time spent gaming and social motivation to play were associated with larger social networks for all participants (strongest for women). More time spent gaming FBR was also associated with a positive impact on life for those with a disability. Social motivation to play was positively associated with a positive impact on life for men and those without a disability and increased well-being for women. Novelty motivation, which concerns experiencing new features in the game, was associated with a positive impact on life for women and with a decrease in well-being for those with a disability. This study demonstrated that gaming can be an essential social arena associated with positive outcomes for men, women and disabled people, who—when socially motivated—may expand their social networks through gaming

Land cover type modulates the distribution of litter in a Nordic cultural landscape

Litter pollution is a global environmental problem that occurs in virtually all ecosystems. Scientific research on anthropogenic litter and its environmental impacts focusses predominantly on plastics and the marine environment. Little empirical knowledge exists about the distribution and ecological impacts of litter in terrestrial environments, where most litter is produced. To start closing that knowledge gap, we investigated the distribution of litter in a cultural landscape in central Norway and in relation to land cover types. We registered and collected litter in 110 survey plots that were randomly stratified across various land cover types. Our results show that land cover type modulates the occurrence, abundance, fragments size, and that litter is most present and abundant in or near land cover types associated with high human activities. Plastic was by far the most common litter material type, although the litter community (in terms of materials type) was not independent from land cover type. This knowledge can help to inform and optimize litter management and clean-up activities in terrestrial landscapes. How and to what extent the spatial structure of the litter community mediates ecological effects across various land cover types remains unknown to a large extent and warrants further study.publishedVersio

Uniform algebras and approximation on manifolds

Let $\Omega \subset \mathbb{C}^n$ be a bounded domain and let $\mathcal{A} \subset \mathcal{C}(\bar{\Omega})$ be a uniform algebra generated by a set $F$ of holomorphic and pluriharmonic functions. Under natural assumptions on $\Omega$ and $F$ we show that the only obstruction to $\mathcal{A} = \mathcal{C}(\bar{\Omega})$ is that there is a holomorphic disk $D \subset \bar{\Omega}$ such that all functions in $F$ are holomorphic on $D$, i.e., the only obstruction is the obvious one. This generalizes work by A. Izzo. We also have a generalization of Wermer's maximality theorem to the (distinguished boundary of the) bidisk

Arctic Summer Sea Ice Melt and Related Atmospheric Conditions in Coupled Regional Climate Model Simulations and Observations

Observations from 1979 to 2014 show a positive trend in the summer sea ice melt rate with an acceleration particularly in June and August. This is associated with atmospheric circulation changes such as a tendency toward a dipole pattern in the mean sea level pressure (SLP) trend with an increase over the Arctic Ocean and a decrease over Siberia. Consistent with previous studies, we here show the statistical relationship between the summer sea ice melt rate and SLP and that more than one SLP pattern is associated with anomalously high melt rates. Most high melt rates occur during high pressure over the Arctic Ocean accompanied by low pressure over Siberia, but a strong Beaufort High and advection of warm air associated with a cyclone located over the Taymyr Peninsula can also trigger anomalous high ice melt. We evaluate 10-member ensemble simulations with the coupled atmosphere-ice-ocean Arctic regional climate model HIRHAM-NAOSIM. The simulations have systematically low acceleration of sea ice melt rate in August, related to shortcomings in representing the strengthening pressure gradient from the Barents/Kara Sea toward Northern Greenland in recent decades. In general, the model shows the same classification of SLP patterns related to anomalous melt rates as the observations. However, the evolution of sea ice melt-related cloud-radiation feedback over the summer reveals contrary effects from low-level clouds in the reanalysis and in the simulations

The DLBCL90 gene-expression assay identifies double-hit lymphomas with high sensitivity in patients from two phase II clinical trials with high-risk diffuse large B-cell lymphoma

Peer reviewe

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell–like diffuse large B cell lymphoma

To elucidate the mechanisms underlying chromosomal translocations in diffuse large B cell lymphoma (DLBCL), we investigated the nature and extent of immunoglobulin class switch recombination (CSR) in these tumors. We used Southern blotting to detect legitimate and illegitimate CSR events in tumor samples of the activated B cell–like (ABC), germinal center B cell–like (GCB), and primary mediastinal B cell lymphoma (PMBL) subgroups of DLBCL. The frequency of legitimate CSR was lower in ABC DLBCL than in GCB DLBCL and PMBL. In contrast, ABC DLBCL had a higher frequency of internal deletions within the switch μ (Sμ) region compared with GCB DLBCL and PMBL. ABC DLBCLs also had frequent deletions within Sγ and other illegitimate switch recombinations. Sequence analysis revealed ongoing Sμ deletions within ABC DLBCL tumor clones, which were accompanied by ongoing duplications and activation-induced cytidine deaminase–dependent somatic mutations. Unexpectedly, short fragments derived from multiple chromosomes were interspersed within Sμ in one case. These findings suggest that ABC DLBCLs have abnormalities in the regulation of CSR that could predispose to chromosomal translocations. Accordingly, aberrant switch recombination was responsible for translocations in ABC DLBCLs involving BCL6, MYC, and a novel translocation partner, SPIB

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P < 1 × 10-4 in an additional 9,412 cases and 137,760 controls. Eight of the 19 variants that were genome-wide significant (P < 5 × 10-8) in the discovery GWAS were not genome-wide significant in the combined analysis, consistent with small effect sizes and limited power but also with genetic heterogeneity. In the combined analysis, 30 loci were genome-wide significant, including 20 newly identified loci. The significant loci contain genes encoding ion channels, neurotransmitter transporters and synaptic components. Pathway analysis revealed nine significantly enriched gene sets, including regulation of insulin secretion and endocannabinoid signaling. Bipolar I disorder is strongly genetically correlated with schizophrenia, driven by psychosis, whereas bipolar II disorder is more strongly correlated with major depressive disorder. These findings address key clinical questions and provide potential biological mechanisms for bipolar disorder

Preliminary results of 3D-DDTC pixel detectors for the ATLAS upgrade

Presented at: 9th International Conference on Large Scale Applications and Radiation Hardness of Semiconductor Detectors - RD09. Florence, Italy, 30 September - 2 October 20093D Silicon sensors fabricated at FBK-irst with the Double-side Double Type Column (DDTC) approach and columnar electrodes only partially etched through p-type substrates were tested in laboratory and in a 1.35 Tesla magnetic field with a 180GeV pion beam at CERN SPS. The substrate thickness of the sensors is about 200μm, and different column depths are available, with overlaps between junction columns (etched from the front side) and ohmic columns (etched from the back side) in the range from 110μm to 150μm. The devices under test were bump bonded to the ATLAS Pixel readout chip (FEI3) at SELEX SI (Rome, Italy). We report leakage current and noise measurements, results of functional tests with Am241 γ-ray sources, charge collection tests with Sr90 β-source and an overview of preliminary results from the CERN beam test.publishedVersio