Planificación y evaluación del Trabajo de Fin de Grado:el caso del Grado en Información y Documentación de la universidad Carlos III de Madrid

In the framework of the European Higher Education Area, the Undergraduate Dissertation is a subject on the official curriculum for the bachelor's degrees that can be earned in Spanish universities, Carlos III University of Madrid among them. It consists of an individual dissertation in which students apply the knowledge, skills and competencies acquired throughout their 4-year courses to a problem specific to the discipline associated with the degree to which they aspire. Planning, conducting and evaluating the work involved in the dissertation call for ad hoc tools that must be designed to accurately appraise the command of specific competencies associated with the degree sought by the student. The present paper introduces three such tools developed for the Bachelor's Degree in Information and Documentation offered at Carlos III University since 2008-09: a guidance manual, a preview system and an evaluation rubric. The guidance manual provides students with clear and precise instructions on how to undertake their study. The preview system affords a consistent, clear procedure for all students and for suitable monitoring of their progress at specified intervals. The evaluation rubric is a consistent and objective marking tool for juries. The three enable students and staff to suitably monitor progress and for professors to consistently and objectively evaluate all students in accordance with the duly weighted categories into which the competencies associated with the bachelor's degree in Information and Documentation are grouped.El Trabajo Fin de Grado (TFG) es, en el marco del Espacio Europeo de Educación Superior (EEES), y en particular en los estudios de Grado que oferta la Universidad Carlos III de Madrid, una asignatura más dentro del plan de estudios. Consiste en la realización de un trabajo de carácter individual, en el que el alumno demuestra los conocimientos, habilidades y competencias adquiridos durante sus estudios a un problema específico del ámbito de la titulación. La planificación, desarrollo y evaluación de esta asignatura supone diseñar instrumentos ad hoc que permitan valorar adecuadamente la adquisición de las competencias específicas ligadas al título de Grado al que opta el alumno. A tal efecto, en este trabajo, se presentan tres herramientas concretas que se han elaborado para el título de Grado en Información y Documentación que se imparte en la Universidad Carlos III de Madrid desde el curso 2008-09: un manual de orientación, un plan de avances y una rúbrica o matriz de evaluación. El primero de ellos, el manual de orientación, ofrece al estudiante una guía clara y precisa de cómo elaborar el trabajo. El segundo, el plan de avances, ha permitido desarrollar un procedimiento claro y unitario para todos los estudiantes y realizar un seguimiento adecuado de los avances de los alumnos con plazos temporales determinados. El tercero, la rúbrica o matriz de evaluación, ha facilitado una herramienta coherente y objetiva de calificación para los tribunales que los evalúan. Todas ellas permiten, tanto a los profesores como a los alumnos, realizar un seguimiento adecuado de los trabajos y una evaluación coherente y objetiva para todos ellos de las 16 competencias asociadas al TFG en el Grado en Información y Documentación con la correspondiente ponderación de sus indicadores

Areas homogéneas de producción agrícola en la provincia de Buenos Aires, Argentina

Al considerarse los registros históricos de rendimientos de granos de girasol, maíz, trigo y soja, durante el período 1970-1993, se delimitaron 22 áreas homogéneas de producción agrícola en la provincia de Buenos Aires. Los rendimientos de los cultivos de maíz y de trigo fueron los principales contribuyentes en la definición de estas regiones. La distribución de áreas se vinculó con los grandes grupos de suelos y geoformas predominantes. Las regiones con menor producción de los cultivos se ubicaron hacia el sudoeste y centro-este de la provincia de Buenos Aires. En cambio, las regiones de mayor producción se detectaron hacia el nor-noreste y sudeste, dependiendo de los cultivos considerados.Twenty two homogeneous agricultural areas were delimited in the Buenos Aires province (Argentine). They were grouped considering sunflower, corn, soybean and wheat annual production in each district during 1970-1 993. The areas were mainly defined according to wheat and corn productivity. Regions were grouped in relation to the principal groups of soils and geoforms. Low agricultural production regions were located on the South-West and Central east, and, on the other hand, high agricultural production areas were located on the North-North east and South east, according to the crops that were considered.EEA General VillegasFil: Diaz Zorita, Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina.Fil: Fernández Canigia, María Virginia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina

Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice

The CC chemokine 1 (CCL1, also called I-309 or TCA3) is a potent chemoattractant for leukocytes that plays an important role in inflammatory processes and diseases through binding to its receptor CCR8. Here, we investigated the role of the CCL1-CCR8 axis in atherosclerosis. We found increased expression of CCL1 in the aortas of atherosclerosis-prone fat-fed apolipoprotein E (Apoe)-null mice; moreover, in vitro flow chamber assays and in vivo intravital microscopy demonstrated an essential role for CCL1 in leukocyte recruitment. Mice doubly deficient for CCL1 and Apoe exhibited enhanced atherosclerosis in aorta, which was associated with reduced plasma levels of the anti-inflammatory interleukin 10, an increased splenocyte Th1/Th2 ratio, and a reduced regulatory T cell (Treg) content in aorta and spleen. Reduced Treg recruitment and aggravated atherosclerosis were also detected in the aortas of fat-fed low-density lipoprotein receptor-null mice treated with CCR8 blocking antibodies. These findings demonstrate that disruption of the CCL1-CCR8 axis promotes atherosclerosis by inhibiting interleukin 10 production and Treg recruitment and function.This study was supported by the Spanish Ministerio de Ciencia, Innovación y Universidades (MCIU, grants SAF2016-79490-R and SAF2014-57845-R) and the Instituto de Salud Carlos III (ISCIII, grants PI14/00526, PI17/01395, CP11/00145, and CPII16/00022) with co-funding from the European Regional Development Fund (ERDF, “Una manera de hacer Europa”), the Fundación Ramón Areces, European Union (EuroCellNet COST Action CA15214) and the INSERM. VZG is supported by the ISCIII, JMG-G by the ISCIII Miguel Servet Program and the Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), AdMM by the MCIU (predoctoral contract BES-2014-06779), and ZM by a British Heart Foundation Professorship. The CNIC is supported by the MCIU and the Pro CNIC Foundation and is a Severo Ochoa Center of Excellence (SEV-2015-0505).S

Predictive Power of the "Trigger Tool" for the detection of adverse events in general surgery: a multicenter observational validation study

Background In spite of the global implementation of standardized surgical safety checklists and evidence-based practices, general surgery remains associated with a high residual risk of preventable perioperative complications and adverse events. This study was designed to validate the hypothesis that a new “Trigger Tool” represents a sensitive predictor of adverse events in general surgery. Methods An observational multicenter validation study was performed among 31 hospitals in Spain. The previously described “Trigger Tool” based on 40 specific triggers was applied to validate the predictive power of predicting adverse events in the perioperative care of surgical patients. A prediction model was used by means of a binary logistic regression analysis. Results The prevalence of adverse events among a total of 1,132 surgical cases included in this study was 31.53%. The “Trigger Tool” had a sensitivity and specificity of 86.27% and 79.55% respectively for predicting these adverse events. A total of 12 selected triggers of overall 40 triggers were identified for optimizing the predictive power of the “Trigger Tool”. Conclusions The “Trigger Tool” has a high predictive capacity for predicting adverse events in surgical procedures. We recommend a revision of the original 40 triggers to 12 selected triggers to optimize the predictive power of this tool, which will have to be validated in future studies

Simulación del comportamiento mecánico de una prótesis de cadera por el método de los elementos finitos

Se presenta una simulación de un prototipo de implante de cadera en el que varía el biomaterial que lo define. De igual modo, se muestra el patrón creado en formato 3D para su importación al software de simulación. El objetivo principal de este trabajo radica en el desarrollo de un modelo, empleando el programa Ansys Workbench, de análisis por el método de los elementos finitos, que sea capaz de emular la respuesta de un tipo de prótesis de cadera bajo condiciones de carga estática.Ingeniería Técnica en Mecánic

Áreas homogéneas de producción agrícola en el este de la provincia de La Pampa

El objetivo de este trabajo fue delimitar áreas con comportamientos homogéneos en la producción agrícola del este de la provincia de La Pampa (Argentina). Para ello se aplicaron técnicas de análisis multivariado (análisis de agrupamiento y componentes principales) a los rendimientos medios anuales por departamento (1980 a 1997) de maíz, girasol, sorgo y trigo. Se delimitaron seis áreas homogéneas de producción agrícola formadas por los siguientes departamentos: 1) Chapaleufú, Maracó y Quemú Quemú, 2) Conhelo, Rancul, Realico, y Trenel, 3) Atreucó, Capital y Catriló, 4) Guatraché, Toay y Utracán, 5) Loventué y 6) Hucal. Esta distribución estarla en relación con los suelos, geoformas predominantes y características climáticas. Las regiones de mayor producción se ubicaron hacia el norte y el este del área estudiada, para todos los cultivos considerados.The objective of this study was to delimitate areas with homogeneous agricultural production behavior in the eastem of La Pampa province (Argentina). Multivariate analysis (cluster and principal component analysis) was done using sunflower, com, sorghum ane wheat departmental annual yieids during the period 1980-1997. Six areas were delimited which were composed by the following departments: 1) Chapaleufú, Marac6 and Quemú Quemú, 2) Conhelo, Rancul, Realic6, and Trenel, 3) Atreuc6, Capital and Catriló, 4) Guatraché, Toay and Utrac4n, 5) Loventué and 6) Hucal. This distribution would be related to solls, geoforms and weather conditions. The areas with high productivity, for the considered crops, were located at the North and the East of the studied region.EEA General VillegasFil: Fernández Canigia, María Virginia. Universidad Nacional de La Pampa. Facultad de Agronomía. Microbiología Agrícola; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina.Fil: Diaz Zorita, Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina

Field performance of a liquid formulation of Azospirillum brasilense on dryland wheat productivity

The beneficial effects of inoculating with Azospirillum brasilense on crop productivity have been widely described, but extensive use in typical agricultural field environments is scarcely documented. The objective of this study was to quantify the productivity of wheat (Triticum aestivum L.) whose seed was inoculated with a liquid formulation containing Azospirillum brasilense INTA Az-39 strain under typical dryland farming conditions. The study was performed in the 2002-2006 growing seasons, evaluating inoculated and non-inoculated seed at 297 experimental locations in the Pampas region of Argentina. The inoculated crops exhibited more vigorous vegetative growth, with both greater shoot and root dry matter accumulation (12.9 and 22.0%, respectively). The inoculation increased the number of harvested grains by 6.1%, and grain yield by 260 kg ha-1 (8.0%). Positive responses were determined in about 70% of the sites, depending mostly on the attainable yield and independently of fertilization and other crop and soil management practices. In general, more response to inoculation was observed in the absence of major crop growth limitations, suggesting the complementary contribution of the Azospirillum brasilense treatment to more efficiently developing higher yielding wheat. © 2008 Elsevier Masson SAS. All rights reserved.Fil: Diaz Zorita, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones en Biociencias Agrícolas y Ambientales. Universidad de Buenos Aires. Facultad de Agronomía. Instituto de Investigaciones en Biociencias Agrícolas y Ambientales; ArgentinaFil: Fernández Canigia, María Virginia. DZD Agro SRL.; Argentin

Soybean nodulation patterns in relation with soil properties under three tillage systems

Se evaluaron los efectos inducidos por tres sistemas de labranza (LC = convencional con arado de rejas, LV = vertical con arado de cinceles, SD = siembra directa) sobre la nodulación de soja (Glycine max (L.) Merrill cv. Prata) y su relación con propiedades edáficas en el momento de la siembra. El estudio se realizó en un Hapludol típico de la región subhúmeda pampeana que presentaba alto número de Bradyrhizobium japonicum naturalizado. Las principales diferencias en nodulación se detectaron en los primeros 5 cm de la raíz principal (P0-5). Cultivos en SD presentaron mayor número, peso seco total (PST) y peso seco individual de los nódulos que en LC y LV (p<0,01). En las dos fechas evaluadas (70 y 119 días después de la siembra) el número y PST de los nódulos en P0-5, se relacionaron positiva y significativamente con el contenido relativo de agua del suelo (0-20 cm) en el momento de la siembra [Número: R2 (70 dds) = 0,77 y R2 (119 dds) = 0,70 p<0,01 y PST: R2 (70 dds) = 0,70 y R2 (119 dds) = 0,73 p<0,01]. Entre los tratamientos de labranzas, no se observaron diferencias en los contenidos N-NO3 del suelo (0-20cm) evaluados en el momento de la siembra, ni en los rendimientos de grano de soja. Ninguna de estas variables se correlacionó significativamente con los patrones de nodulación observados. Se concluye que las mejores condiciones de humedad en el ambiente edáfico provistas por el sistema de SD favorecieron la mayor infección inicial de B. japonicum.Soybean (Glycine max (L.) Merrill cv. Prata) nodulation patterns were evaluated under three tillage systems (LC = conventional tillage or moldboard plowing, LV = vertical tillage or chisel plowing and SD = no-till or direct drilling). The study was done in a Typic Hapludoll from the pampean subhumid region. The soil presented a high number of naturalized Bradyrhizobium japonicum. The mean differences in nodulation were detected in the upper 5 cm of the main root (P0-5). The number, the total dry weight (PST) and the individual dry weight of the nodules were higher under SD than under LV and LC (p<0.01). In the two evaluation dates (70 and 119 days after planting), the differences in P0-5 nodulation were positively related with the relative soil water content (0-20 cm) at sowing [Number: R2 (70 dds) = 0.77 and R2 (119 dds) = 0.70 p<0.01 and PST: R2 (70 dds) = 0.70 and R2 (119 dds) = 0.73 p<0.01]. Neither difference due to the tillage systems in the soil NNO3 levels and in the soybean grain yields, nor correlation with the nodulation pattern were observed. We conclude that the better moisture conditions in the soil during the seeding under SD favored the initial infection with Bradyrhizobium japonicum.Facultad de Ciencias Agrarias y Forestale

Soybean nodulation patterns in relation with soil properties under three tillage systems

Se evaluaron los efectos inducidos por tres sistemas de labranza (LC = convencional con arado de rejas, LV = vertical con arado de cinceles, SD = siembra directa) sobre la nodulación de soja (Glycine max (L.) Merrill cv. Prata) y su relación con propiedades edáficas en el momento de la siembra. El estudio se realizó en un Hapludol típico de la región subhúmeda pampeana que presentaba alto número de Bradyrhizobium japonicum naturalizado. Las principales diferencias en nodulación se detectaron en los primeros 5 cm de la raíz principal (P0-5). Cultivos en SD presentaron mayor número, peso seco total (PST) y peso seco individual de los nódulos que en LC y LV (p<0,01). En las dos fechas evaluadas (70 y 119 días después de la siembra) el número y PST de los nódulos en P0-5, se relacionaron positiva y significativamente con el contenido relativo de agua del suelo (0-20 cm) en el momento de la siembra [Número: R2 (70 dds) = 0,77 y R2 (119 dds) = 0,70 p<0,01 y PST: R2 (70 dds) = 0,70 y R2 (119 dds) = 0,73 p<0,01]. Entre los tratamientos de labranzas, no se observaron diferencias en los contenidos N-NO3 del suelo (0-20cm) evaluados en el momento de la siembra, ni en los rendimientos de grano de soja. Ninguna de estas variables se correlacionó significativamente con los patrones de nodulación observados. Se concluye que las mejores condiciones de humedad en el ambiente edáfico provistas por el sistema de SD favorecieron la mayor infección inicial de B. japonicum.Soybean (Glycine max (L.) Merrill cv. Prata) nodulation patterns were evaluated under three tillage systems (LC = conventional tillage or moldboard plowing, LV = vertical tillage or chisel plowing and SD = no-till or direct drilling). The study was done in a Typic Hapludoll from the pampean subhumid region. The soil presented a high number of naturalized Bradyrhizobium japonicum. The mean differences in nodulation were detected in the upper 5 cm of the main root (P0-5). The number, the total dry weight (PST) and the individual dry weight of the nodules were higher under SD than under LV and LC (p<0.01). In the two evaluation dates (70 and 119 days after planting), the differences in P0-5 nodulation were positively related with the relative soil water content (0-20 cm) at sowing [Number: R2 (70 dds) = 0.77 and R2 (119 dds) = 0.70 p<0.01 and PST: R2 (70 dds) = 0.70 and R2 (119 dds) = 0.73 p<0.01]. Neither difference due to the tillage systems in the soil NNO3 levels and in the soybean grain yields, nor correlation with the nodulation pattern were observed. We conclude that the better moisture conditions in the soil during the seeding under SD favored the initial infection with Bradyrhizobium japonicum.Facultad de Ciencias Agrarias y Forestale

Lamin A/C deficiency in CD4+ T-cells enhances regulatory T-cells and prevents inflammatory bowel disease

The mechanisms by which lamin A/C in CD4+ T-cells control intestinal homeostasis and can cause inflammatory bowel disease (IBD) are unknown. Here, we explore lamin A/C in a mouse model of IBD. Adoptive transfer to Rag1-/- mice of Lmna-/- CD4+ T-cells, which have enhanced regulatory T-cells (Treg) differentiation and function, induced less severe IBD than wild-type T-cells. Lamin A/C deficiency in CD4+ T-cells enhanced transcription of the Treg master regulator FOXP3, thus promoting Treg differentiation, and reduced Th1 polarization, due to epigenetic changes in the Th1 master regulator T-bet. In mesenteric lymph nodes, retinoic acid (RA) released by CD103+ dendritic cells downregulated lamin A/C in CD4+ T-cells, enhancing Treg differentiation. However, non-RA-producing CD103- dendritic cells predominated in peripheral lymph nodes, facilitating lamin A/C expression in CD4+ T-cells and therefore Th1 differentiation. Our findings establish lamin A/C as a key regulator of Th differentiation in physiological conditions and show it as a potential immune-regulatory target in IBD. © 2019 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.This study was supported by grants to PC from the Research Council of Norway, to JMG-G from ISCIII (PI14/00526; PI17/01395; CP11/00145; CPII16/00022; EuroCellNet COST Action CA15214), the Miguel Servet Program and Fundación Ramón Aréces; to VA (RD12/0042/0028 SAF2013-46663-R, SAF2016-79490-R); to FS-M (SAF2017-82886-R; ERC-2011-AdG 294340-GENTRIS, CIBER CARDIOVASCULAR, PIE 13.0004-BIOIMID and CAM-B2017/BMD-3671-INFLAMUNE), to GC and JLP (PI16/00032 and RETICs RD16/0012 RIER), and to JV (BIO2015-67580-P; PRB3, IPT17/0019 - ISCIII-SGEFI/ERDF, ProteoRed) with co-funding from the European Regional Development Fund (ERDF) “Una manera de hacer Europa”. The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia, Innovación y Universidades (MCNU) and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505). RTF is supported by the Fundación Ramón Aréces, VZG by ISCIII, BHF by the Instituto de Investigación Hospital 12 de Octubre (i+12), and JMG-G by the ISCIII Miguel Servet Program, i+12 and Universidad Autónoma de Madrid (UAM).S