New Methods for ferrous raw materials characterization in electric steelmaking

425 p.In the siderurgical sector, the steel scrap is the most important raw material in electric steelmaking,contributing between 70% of the total production costs. It is well-known how the degree of which thescrap mix can be optimized, and also the degree of which the melting operation can be controlled andautomated, is limited by the knowledge of the properties of the scrap and other raw-materials in thecharge mix.Therefore, it is of strategic importance having accurate information about the scrap composition of thedifferent steel scrap types. In other words, knowing scrap characteristics is a key point in order to managethe steel-shop resources, optimize the scrap charge mix/composition at the electric arc furnace (EAF),increase the plant productivity, minimize the environmental footprint of steelmaking activities and tohave the lowest total cost of ownership of the plant.As a main objective of present doctoral thesis, the doctorate will provide new tools and methods of scrapcharacterization to increase the current recycling ration, through better knowledge of the quality of thescrap, and thus go in the direction of a 100% recycling ratio. In order to achieve it, two main workinglines were developed in present research. Firstly, it was analysed not only the different existingmethodologies for scrap characterization and EAF process optimization, but also to develop new methodsor combination of existing, Secondly, it was defined a general recommendations guide for implementingthese methods based on the specifics of each plant

Biostratigraphic study with planktic foraminifera of the Santonian-Campanian in the Deba-Zumaia section (Gipuzkoa): New biozonation with heterohelicids

A biostratigraphic study with Santonian and Campanian planktic foraminifera was carried out in the turbiditic facies of the coastline between Deba and Zumaia (Gipuzkoa), which comprises the Itziar and Aguinaga formations. Due to the low abundance of planktic foraminifera, particularly in globotruncanids, the biostratigraphic study was based on species belonging to the group of heterohelicids. We have identified 7 biozones, one of which (Sigalia rugocostata Zone) has been defined in this work. The position of the Santonian/Campanian boundary has been recognized for the first time in the Basque Coast Geopark through the use of this new biozonation with heterohelicidsSe ha realizado un estudio bioestratigráfico con foraminíferos planctónicos del Santoniense y Campaniense en las facies turbidíticas del tramo litoral entre Deba y Zumaia (Guipúzcoa), el cual comprende las formaciones Itziar y Aguinaga. Debido a la escasez de foraminíferos planctónicos del grupo de globotruncánidos, el estudio bioestratigráfico se ha basado en especies pertenecientes al grupo de los heterohelícidos. Se han identificado 7 biozonas, una de las cuales (Zona de Sigalia rugocostata) ha sido definida en este trabajo. Esta nueva biozonación ha permitido reconocer por primera vez la posición del límite Santoniense/Campaniense en el Geoparque de la Costa Vasc

Evaluation of gym users’ diet with muscle dysmorphia (bigorexia)

Objetivo: se muestra un estudio novedoso en el cual se ha analizado la dieta entre usuarios de gimnasio de la provincia de Alicante que padecen dismorfia muscular (DM). Metodología: se analizaron 141 gimnastas varones de varias salas de musculación de Alicante (zona urbana del sureste español) de edad entre 18-45 años, que persiguen el aumento de su masa muscular. Se tuvieron en cuenta el IMC (kg/m2) y la dieta realizada durante 24 horas. Y se ha determinado si padecían o no DM, a través de la Escala de satisfacción muscular. Resultados: la muestra está constituida por 141 varones, de los cuales 45 padecen DM y 96 no, según la Escala de satisfacción muscular. Se calculó el consumo de proteínas, siendo superior a 1,5 g/kg/día en el grupo sin DM y superior a 2 g/kg/día en el grupo con DM. Al analizar los demás macronutrientes los resultados indican que la proporción de hidratos de carbono, grasas y sus porcentajes según grado de insaturación están dentro de las recomendaciones, excepto el colesterol, que las supera, y la cantidad de fibra, que es ligeramente inferior. En relación a los micronutrientes en todos los casos están dentro de las recomendaciones excepto en el caso del yodo, que en los DM es ligeramente inferior. Conclusión: los individuos con DM realizan una dieta normocalórica y adecuada en hidratos de carbono y lípidos; sin embargo, los valores de proteína ingerida exceden los límites propuestos según la evidencia científica para el desarrollo de masa muscular en los deportes de fuerza.Objective: it is an innovative study where has been analyzed the diet among gym users with Muscle Dysmorphia (MD) of gyms in the province of Alicante. Methodology: it have been analyzed 141 male gymnasts of several gyms of Alicante (urban area of southeastern Spanish) aged between 18-45 years old, who purpose increasing their muscle mass. Were considered BMI (kg/m2) and 24 hour diet. And it has been determined whether or not suffer MD trough Muscle Appearance Satisfaction Scale. Results: the sample consisted of 141 men, of whom 45 are MD and 96 are not according to Muscle Appearance Satisfaction. Protein intake was calculated and was greater than 1.5 g/kg/day in patients without MD and greater than 2 g/kg/day in the MD group. Analyzing the other nutrients, results show that the proportion of carbohydrates and fats and their percentages by degree of instauration are within the recommendations except cholesterol which exceeds and the amount of dietary fiber that is slightly lower. In relation to micronutrients are within the recommendations in all cases except iodine which is slightly lower in MD. Conclusion: individuals with MD do a balanced energy and adequate carbohydrate and fat diet, however protein intake values exceed the limits proposed according to the scientific evidence for muscle mass development in strength sports

A Probabilistic Model and Capturing Device for Remote Simultaneous Estimation of Spectral Emissivity and Temperature of Hot Emissive Materials

Estimating the temperature of hot emissive samples (e.g. liquid slag) in the context of harsh industrial environments such as steelmaking plants is a crucial yet challenging task, which is typically addressed by means of methods that require physical contact. Current remote methods require information on the emissivity of the sample. However, the spectral emissivity is dependent on the sample composition and temperature itself, and it is hardly measurable unless under controlled laboratory procedures. In this work, we present a portable device and associated probabilistic model that can simultaneously produce quasi real-time estimates for temperature and spectral emissivity of hot samples in the [0.2, 12.0μm ] range at distances of up to 20m . The model is robust against variable atmospheric conditions, and the device is presented together with a quick calibration procedure that allows for in field deployment in rough industrial environments, thus enabling in line measurements. We validate the temperature and emissivity estimates by our device against laboratory equipment under controlled conditions in the [550, 850∘C ] temperature range for two solid samples with well characterized spectral emissivity’s: alumina ( α−Al2O3 ) and hexagonal boron nitride ( h−BN ). The analysis of the results yields Root Mean Squared Errors of 32.3∘C and 5.7∘C respectively, and well correlated spectral emissivity’s.This work was supported in part by the Basque Government (Hazitek AURRERA B: Advanced and Useful REdesign of CSP process for new steel gRAdes) under Grant ZE-2017/00009

Análisis de competitividad de las exportaciones: un nuevo enfoque shift-share

[email protected] [email protected] [email protected] trabajo utiliza un método de shift-share como herramienta para analizar la evolución de la competitividad exterior de una economía. Frente a otros indicadores tradicionales de competitividad (cuota de mercado, índice de ventaja comparativa revelada), este método ofrece una perspectiva dinámica para la evaluación de la competitividad exterior y permite descender desde niveles agregados (sectores) hasta productos específicos, identificando de este modo el origen de las ventajas-desventajas competitivas de una economía. Se presenta una aplicación para el sector de manufacturas del metal de la Comunidad Valenciana en el período 1996-2006. De este modo se identifican, en el sector referido, los subsectores y productos en los que esta comunidad autónoma obtuvo una ganancia de competitividad

A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants

Background: Gain of function (GOF) mutations of PCSK9 cause autosomal dominant familial hypercholesterolemia as they reduce the abundance of LDL receptor (LDLR) more efficiently than wild-type PCSK9. In contrast, PCSK9 loss of function (LOF) variants are associated with a hypocholesterolemic phenotype. Dozens of PCSK9 variants have been reported, but most remain of unknown significance since their characterization has not been conducted. Objective: Our aim was to make the most comprehensive assessment of PCSK9 variants and to determine the simplest approach for the classification of these variants. Methods: The expression, maturation, secretion, and activity of nine well-established PCSK9 variants were assessed in transiently transfected HEK293 cells by Western blot and flow cytometry. Their extracellular activities were determined in HepG2 cells incubated with the purified recombinant PCSK9 variants. Their binding affinities toward the LDLR were determined by solid-phase immunoassay. Results: LDLR expression increased when cells were transfected with LOF variants and reduced when cells were transfected with GOF variants compared with wild-type PCSK9. Extracellular activities measurements yielded exactly similar results. GOF and LOF variants had increased, respectively reduced, affinities for the LDLR compared with wild-type PCSK9 with the exception of one GOF variant (R218S) that showed complete resistance to inactivation by furin. All variants were expressed at similar levels and underwent normal maturation and secretion patterns except for two LOF and two GOF mutants. Conclusions: We propose that transient transfections of HEK293 cells with a plasmid encoding a PCSK9 variant followed by LDLR expression assessment by flow cytometry is sufficient to reliably determine its GOF or LOF status. More refined experiments should only be used to determine the underlying mechanism(s) at hand.This work was supported by the Basque Government (Grupos Consolidados IT-1264-19). GL is supported by the Agence Nationale de la Recherche (Paris, France) Program Grant CHOPIN (CHolesterol Personalized Innovation) ANR-16-RHUS-0007 and Project Grant KRINGLE2 ANR-20-CE14-0009 as well as by La Fondation De France (FDF-00096274). U.G-G. was supported by Fundación Biofísica Bizkaia. A.B.-V. was supported by Programa de especialización de Personal Investigador Doctor en la UPV/EHU (2019) 2019-2020. A.L.-S. was supported by a grant PIF (2019–2020), Gobierno Vasco, and partially supported by Fundación Biofísica Bizkaia. KC and AKJ received a scholarship from the European Union (European Regional Development Fund INTERREG V) and the Région Réunion (Saint-Denis, Réunion, France)

Pathophysiology of Atherosclerosis

Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and, followed by a cascade of events (accumulation of lipids, fibrous elements, and calcification), triggers the vessel narrowing and activation of inflammatory pathways. The resultant atheroma plaque, along with these processes, results in cardiovascular complications. This review focuses on the different stages of atherosclerosis development, ranging from endothelial dysfunction to plaque rupture. In addition, the post-transcriptional regulation and modulation of atheroma plaque by microRNAs and lncRNAs, the role of microbiota, and the importance of sex as a crucial risk factor in atherosclerosis are covered here in order to provide a global view of the disease.This work was supported by the Basque Government (Grupos Consolidados IT-1264-19). A.B.-V. was supported by Programa de especialización de Personal Investigador Doctor en la UPV/EHU (2019) 2019/2020; U.G-G. was supported by Margarita Salas Grant; and S.J. and A.L-S were supported by a grant PIF (2017–2018) and PIF (2019–2020) Gobierno Vasco, respectively

Magnetic field-based arc stability sensor for electric arc furnaces

During the last decades the strategy to define the optimal Electric Arc Furnaces (EAF) electrical operational parameters has been constantly evolving. Foaming slag practice is currently used to allow high power factors that ensures higher energy efficiency. However, this performance depends on strict electric arc stability control. Control strategies for these are normally defined for alternating current furnaces (AC EAF) and are based on intrusive and highly expensive systems. In this work we analyze the variation of the magnetic field vector around the direct current EAF (DC EAF) and its relationship with arc stability. We propose a cheap stability control system with no installation or integration requirements and thus, easily implementable to both AC and DC EAFs. To this end we have built a non-intrusive and low-cost 3-axis Hall-effect sensor that can be mounted neighboring the furnace’s electrical bars. The sensor allows acquiring the magnetic field magnitude and orientation that provides a newly defined arc stability factor metric. This proposed Arc Stability Index has been compared with three different alternative well established and more expensive measurement methodologies obtaining with similar results. The proposed index serves as a closed loop signal to the electrical regulation for controlling the arc voltage, ensuring the most convenient arc length that guaranties non-instabilities. The new system was developed and industrially validated at two different DC EAF’s in ArcelorMittal demonstrating an improvement of 6.7 kWh per Liquid steel ton during the evaluated period and a time reduction of 1.1 min per heat over the current standard procedure. Additional validation tests were also carried out also in ArcelorMittal AC EAF proving the capability of this technology for both AC and DC of furnaces.Partial financial support of this work by the Basque Govern-ment (Hazitek AURRERAB ZE-2017/00009 and FASIN ZE-2016/0016 Projects) is gratefully acknowledged