Intervención con personas afectadas por una demencia y sus familiares en el ámbito rural gallego

[Resumen] Introducción: La demencia es uno de los problemas de salud pública más importantes a los que se enfrenta nuestra sociedad. La dispersión geográfica, propia del rural gallego, unida al envejecimiento poblacional de nuestra comunidad, conlleva a que una gran parte de la población que está viviendo esta problemática, no tenga acceso a recursos de apoyo tanto dirigidos a los familiares como a las personas afectadas. Objetivo: Diseñar un programa de intervención desde terapia ocupacional con personas afectadas por una demencia y sus familiares en el ámbito rural gallego. Metodología: Se basa en una metodología de tipo mixto, en el que se va a emplear metodología cualitativa y cuantitativa. La selección de la población de estudio se va a realizar mediante un muestreo por conveniencia. Para la recogida de datos se va a hacer uso de una entrevista semiestructurada para las familias y diferentes escalas en el caso de las personas afectadas. Este proyecto se llevará a cabo en los diferentes centros municipales del ayuntamiento de Oleiros y con la colaboración de la asociación de familiares y enfermos de alzheimer y otras demencias de A Coruña (AFACO).[Abstract] Introduction: Dementia is one of the most important health issues facing our society. Geographical dispersion and population aging are typical features within Galician rural population, hindering the access to support resources for both the affected people and their relatives. Objective: Designing an intervention program on people with dementia and their relatives within Galician rural population for occupational therapy. Methodology: It is based on a mixed methodology, merging both qualitative and quantitative methodologies. Selection of the study population is performed by convenience sampling. Data collection is carried out by using semi-structured interviews for families and different scales for those people affected. This Project will be conducted in several municipal centers within the municipality of Oleiros and in collaboration with the Alzheimer´s Disease and Dementia Patients and Relatives Association of A Coruña (Asociación de Familiares y enfermos de Alzheimer y otras demencias de A Coruña aka AFACO).Traballo fin de grao (UDC.FCS). Terapia ocupacional. Curso 2013/2014

Bioactive compounds of Verbascum sinuatum L.: health benefits and potential as new ingredients for industrial applications

Verbascum sinuatum (V. sinuatum) is a plant belonging to the Scrophulariaceae family that has been used as an ingredient in traditional medicine infusions for the treatment of many diseases. The aerial part of this plant is a source of bioactive compounds, especially polyphenols and iridoids. Moreover, antioxidant activity studies have shown that V. sinuatum phenolic and flavonoid composition is higher than those in other plants of the same genus. V. sinuatum bioactive compound composition could vary according to the harvesting location, growing conditions of the plants, sample preparation methods, type and concentration of the extraction solvent, and the extraction methods. The obtention of these compounds can be achieved by different extraction techniques, most commonly, maceration, heat assisted extraction, and infusion. Nevertheless, since conventional extraction techniques have several drawbacks such as long times of extraction or use of large amounts of solvents, the use of green extraction techniques is suggested, without affecting the efficiency of the extraction. Moreover, V. sinuatum bioactive compounds have several biological activities, such as antioxidant, anticancer, cardiovascular, antimicrobial, antidiabetic, and neuroprotective activities, that may be increased by encapsulation. Since the bioactive compounds extracted from V. sinuatum present good potential as functional food ingredients and in the development of drugs or cosmetics, this review gives an approach of the possible incorporation of these compounds in the food and pharmacological industries.MICINN | Ref. RYC-2017-22891Xunta de Galicia | Ref. ED481B-2021/152Argentinean Agency for the Scientific and Technological Promotion | Ref. PICT (2020)/1602Xunta de Galicia | Ref. ED431F 2020/1

Las investigaciones psicoeducativas sobre estudios de caso/s: relevamiento y análisis de aspectos : Ético-procedimentales

Esta comunicación forma parte del plan de trabajo de una Beca de Estímulo a las Vocaciones Científicas (EVC, CIN-UNLP), desarrollada en el contexto del proyecto de investigación “Diseños de Investigación en Psicología (Parte II): análisis exploratorio-descriptivo sobre Estudios de Caso/s”, radicado en la Facultad de Psicología. El proyecto se propone realizar una sistematización sobre el uso de los diseños de estudio de caso/s (DEC), en diferentes áreas de aplicación de la psicología, sus modos actuales de presentación y tipificación. La comprensión del significado de la experiencia singular que permiten los DEC, genera que sean frecuentemente incorporados a las investigaciones en nuestra disciplina y especialmente en las investigaciones de tipo psicoeducativas. Sin embargo, los aspectos metodológicos y éticos, necesarios para un adecuado análisis de su función en el proceso de una indagación científica, no siempre son explicitados. Es por ello que, en este trabajo, se indagan los aspectos ético-procedimentales que son tomados en cuenta para el manejo de los participantes y comunicados en diferentes publicaciones. Este estudio conforma un diseño bibliográfico de tipo exploratorio, centrado en el análisis ético-metodológico de las investigaciones publicadas en el área. Se han relevado un total de 91 artículos relacionados a investigaciones psicoeducativas de los últimos cinco años correspondientes a las siguientes revistas: Revista de Psicología. Segunda Época (UNLP), Revista Orientación y Sociedad (UNLP), Anuario de Investigaciones (UBA), Investigaciones en Psicología (UBA), Revista IRICE (CONICET-UNR) y Revista Anuario de Investigaciones en Psicología (UNC). Mientras que 24 de estos artículos corresponden a DEC, en sólo seis se comunican las consideraciones éticas que se han tenido en cuenta en el desarrollo de la investigación. Sostenemos que la necesaria explicitación de los aspectos éticos integrados al proceso investigativo en este tipo de estudios, resulta de suma relevancia en pos de un manejo prudencial y respetuoso de los sujetos investigados.Facultad de Psicologí

Development of a novel magnetic reactor based on nanostructured Fe3O4@PAA as heterogenous Fenton catalyst

With the recent development of nanotechnology, magnetic nanoparticles (mNPs) have received increasing attention as potential heterogeneous Fenton catalysts in wastewater treatment applications, as an alternative to the conventional Fenton process using dissolved iron salts. Due to their superparamagnetic properties, Fe3O4 mNPs can be easily recovered and reused by applying a magnetic field. However, Fe3O4 mNPs have a marked tendency to form aggregates in water, leading to a decrease in their catalytic yield. To overcome these limitations, this work explores the catalytic activity of Fe3O4 coated with poly(acrylic acid) (Fe3O4@PAA) as stabilized Fenton heterogeneous nanocatalyst, in the degradation of C.I. Reactive Blue 19 (RB19). To maximize the catalytic potential of Fe3O4@PAA, an experimental design based on the Response Surface Methodology (RSM) has been developed to optimize the conditions of the Fenton process in terms of Fe3O4@PAA concentration (100–300 mg L−1) and H2O2 dose (100–400 mg L−1). Based on the results obtained, a novel sequential batch reactor (SBR) coupled to an external magnetic separation system has been developed, guaranteeing the complete retention of the mNPs in the system. This system allows the reuse of Fe3O4@PAA for at least 10 consecutive cycles, with a successful decolorization of RB19 after 4 h of treatmentThis research was supported by two projects granted by Spanish Ministry of Science and Innovation: MODENA Project CTQ2016-79461-R and CLUSTERCAT Project MAT2015-67458-P, and Fundación Ramon Areces, Spain (Project CIVP18A3940). The authors belong to the Galician Competitive Research Groups ED431C-2017/22 and ED431C-2017/29, programme co-funded by FEDER, CRETUS Strategic Partnership (AGRUP2015/02) and AEMAT (ED431E 2018/08)S

Pressurized liquid extraction for the recovery of bioactive compounds from seaweeds for food industry application: a review

Seaweeds are an underutilized food in the Western world, but they are widely consumed in Asia, with China being the world’s larger producer. Seaweeds have gained attention in the food industry in recent years because of their composition, which includes polysaccharides, lipids, proteins, dietary fiber, and various bioactive compounds such as vitamins, essential minerals, phenolic compounds, and pigments. Extraction techniques, ranging from more traditional techniques such as maceration to novel technologies, are required to obtain these components. Pressurized liquid extraction (PLE) is a green technique that uses high temperatures and pressure applied in conjunction with a solvent to extract components from a solid matrix. To improve the efficiency of this technique, different parameters such as the solvent, temperature, pressure, extraction time and number of cycles should be carefully optimized. It is important to note that PLE conditions allow for the extraction of target analytes in a short-time period while using less solvent and maintaining a high yield. Moreover, the combination of PLE with other techniques has been already applied to extract compounds from different matrices, including seaweeds. In this way, the combination of PLE-SFE-CO2 seems to be the best option considering both the higher yields obtained and the economic feasibility of a scaling-up approximation. In addition, the food industry is interested in incorporating the compounds extracted from edible seaweeds into food packaging (including edible coating, bioplastics and bio-nanocomposites incorporated into bioplastics), food products and animal feed to improve their nutritional profile and technological properties. This review attempts to compile and analyze the current data available regarding the application of PLE in seaweeds to determine the use of this extraction technique as a method to obtain active compounds of interest for food industry application.Ibero–American Program on Science and Technology | Ref. P317RT0003SYSTEMIC Knowledge Hub on Nutrition and Food Security | Ref. 696295Ministerio de Ciencia e Innovación | Ref. RYC-2017-22891Xunta de Galicia | Ref. ED431F 2020/12Xunta de Galicia | Ref. ED481B-2021/152Xunta de Galicia | Ref. ED481A 2021/31

Selective C-H Bond Functionalization of Unprotected Indoles by Donor-Acceptor Carbene Insertion

Copper catalysts containing alkoxydiaminophosphine (ADAP) ligand catalyze the selective C3- H functionalization of unprotected indoles upon carbene transfer from donor-acceptor diazo compounds, the N-H bond remaining unaltered during the transformation. Mechanistic studies, including DFT calculations, allows proposing the existence of two competitive pathways, none of them occurring through the formation of cyclopropane intermediates, at variance with previously reported systems.We thank to Ministerio de Ciencia e Innovación for Grants PID2020-113797RB-C21, PID2020-112825RB-I00 and CEX2019-000925-S. We also thank Junta de Andalucía (P18-1536) and Universidad de Huelva (P. O.Feder UHU-202024). I.-G. F thanks the Investigo Program for a contract. L. M.-G. thanks Generalitat de Catalunya for an FI-Agaur predoctoral contract, 2022FI−B2000621

Marginal changes at bone-level implants supporting fixed screw-retained partial implant prostheses with or without intermediate standardised abutments: 1-year results of a randomised controlled clinical trial

Objective: To compare marginal changes at bone- level implants restored with screw- retained implant prosthesis with or without intermediate standardised abutments, after 1 year of follow-up.Materials and Methods: Thirty- six partially edentulous patients received 72 implants. Each patient received 2 implants and a 2- to 4- unit screw- retained implant- prosthesis. The test group received implants consisting of a screw- retained prosthesis connected directly to the implant shoulder, while the prostheses in the control group were con-nected through a 3- mm standardised intermediate abutment. Clinical and radiological data were recorded at baseline and at 3, 6 and 12 months in follow-up visits.Results: At 12 months, the marginal bone loss was 0.17 ± 0.24 mm for the test group (19 patients) and 0.09 ± 0.15 mm for the control group (17 patients), with no statistically significant differences (p> .05). The mean probing pocket depth was 2.96 mm ± 0.46 for the test group and 2.86 ± 0.62 mm for the control group. The test and control groups showed bleeding on probing levels of 18.86 ± 14.12% and 13.73 ± 17.66%, re-spectively. All patients scored below 25% on the plaque index levels.Conclusions: Restoration of bone- level implants with fixed screw- retained partial prostheses with or without intermediate abutments presented similar radiographic and clinical outcomes after 1 yearS

Direct Magnetic Evidence, Functionalization, and Low-Temperature Magneto-Electron Transport in Liquid-Phase Exfoliated FePS3

Magnetism and the existence of magnetic order in a material is determined by its dimensionality. In this regard, the recent emergence of magnetic layered van der Waals (vdW) materials provides a wide playground to explore the exotic magnetism arising in the two-dimensional (2D) limit. The magnetism of 2D flakes, especially antiferromagnetic ones, however, cannot be easily probed by conventional magnetometry techniques, being often replaced by indirect methods like Raman spectroscopy. Here, we make use of an alternative approach to provide direct magnetic evidence of few-layer vdW materials, including antiferromagnets. We take advantage of a surfactant-free, liquid-phase exfoliation (LPE) method to obtain thousands of few-layer FePS3 flakes that can be quenched in a solvent and measured in a conventional SQUID magnetometer. We show a direct magnetic evidence of the antiferromagnetic transition in FePS3 few-layer flakes, concomitant with a clear reduction of the Néel temperature with the flake thickness, in contrast with previous Raman reports. The quality of the LPE FePS3 flakes allows the study of electron transport down to cryogenic temperatures. The significant through-flake conductance is sensitive to the antiferromagnetic order transition. Besides, an additional rich spectra of electron transport excitations, including secondary magnetic transitions and potentially magnon-phonon hybrid states, appear at low temperatures. Finally, we show that the LPE is additionally a good starting point for the mass covalent functionalization of 2D magnetic materials with functional molecules. This technique is extensible to any vdW magnetic familyE.B. acknowledges funds from Ministerio de Ciencia e Innovación in Spain (RTI2018-096075-A-C22, RYC2019- 028429-I). E.M.P. thanks the Spanish Ministerio de Ciencia e Innovación (PID2020-116661RB-I00) and Comunidad de Madrid (P2018/NMT-4367). M.G.H. and A.C.-G. acknowledge funds from European Union Horizon 2020 research and innovation program (Graphene Core3-Grant agreement no. 881603 Graphene-based disruptive technologies), EU FLAGERA through the project To2Dox (JTC-2019-009), and Comunidad de Madrid through the project CAIRO-CM project (Y2020/NMT-6661). A.C.-G. also acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 755655, ERC-StG 2017 project 2D-TOPSENSE) and the Ministry of Science and Innovation (Spain) through the project PID2020-115566RB-I00. M.L.R.G. acknowledges support by the Spanish Ministry of Science and Innovation through Research Project PID 2020- 113753RB-100. The National Centre for Electron Microscopy (ELECMI National Singular Scientific Facility) is also acknowledge for provision of access to corrected aberration microscopy facilities. CzechNanoLab Research Infrastructure supported by MEYS CR (LM2018110) is acknowledge

Naturaleza de la posverdad. Alcance del fenómeno en el Estado de Derecho y claves para un periodismo de calidad

Aclarar la naturaleza de la posverdad es el punto de partida de este trabajo que pretende abordar sus efectos en la verdad y la justicia. En la primera parte se aborda el análisis de la naturaleza de la posverdad e incide en el contexto y circunstancia, tanto comunicativa como de época, que constituyen el hábitat presente del fenómeno. Como término ha nacido a finales de siglo pasado, en la era de los medios de comunicación de masas, y su problemática está siendo investigada particularmente en los medios digitales contemporáneos de distribución masiva de información. Medios que juegan un papel fundamental en la formación de la opinión pública. Una vez aclarada la vinculación entre posverdad, verdad y opinión, en este trabajo se presenta un análisis de cómo la información periodística puede llegar a ser una fuente de posverdad en asuntos delicados como es el caso de las informaciones de procesos judiciales donde la presencia del fenómeno puede dañar pilares del Estado de Derecho como la presunción de inocencia o la protección de ciudadanos o colectivos en una circunstancia de especial vulnerabilidad. En este sentido, este trabajo aporta claves para frenar la posverdad a partir de una información periodística de calidad

Lidocaína endovenosa domiciliaria en cuidados paliativos

Introduction: Neuropathic pain is a often difficult to control pain and is suitable of different therapeutic approaches. Method: Lidocaine is a local anesthesic and its endovenous use is sometimes necessary to control neuropathic pain. There is no reported use of this drug at home. Results: We performed the lidocaine endovenous infusion in two patients with neuropathic pain achieving significant clinical improvement. Conclusions: Endovenous lidocaine infusion at home, is a safe and effective proceeding for patients with neuropathic pain.Introducción: El dolor neuropático es, en numerosas ocasiones, un dolor de difícil manejo que precisa la combinación de diferentes grupos terapéuticos para su control óptimo. Método: La lidocaína es un anestésico local y su uso endovenoso es necesario ocasionalmente para el tratamiento del dolor neuropático; no hay experiencia en su uso domiciliario. Resultados: Realizamos la infusión endovenosa domiciliaria con lidocaína en 2 pacientes con dolor neuropático refractario con mejoría clínica. Conclusiones: La infusión de lidocaína endovenosa en domicilio es una técnica segura y eficaz en pacientes con dolor neuropático