A retrospective epidemiological study of parasitic otitis in cattle in South-East Lowveld of Zimbabwe

(Zimbabwe Veterinary Journal, 1999, 30(1): 19-24

The Role of Production Planning in Enhancing an Efficient Manufacturing System – An Overview

Every manufacturing system can only survive with a high level of system planning and budgeting. Production planning is a sequential ladder in the manufacturing setting to ensure that materials input (raw materials, men, money, and machine) is made available within a stipulated time frame, in the appropriate amount to produce the demanded output of goods and services based on the schedule specified. Production planning also helps in making available high quality of goods and services in the right quantities to the customer at the demanded delivery timing to attain higher degree of customer satisfaction. Through production planning, different departmental activities i.e., engineering, production, purchasing, sales, and marketing, as well as stock control department, and other units that may relate to production are coordinated to attain a regular, steady, and balanced flow of production thus, enhancing reduction in production cycle time. Production planning serves as an instrument which estimates to gear up the performance of different departments and individuals of an organization in such a manner that will enhance better service to customers, fewer rush orders, more efficient use of equipment, reduced idle time of both machine and personnel, improved plant morale, good public image, and lower capital requirement, it may also create alternative plans to meet any form of emergency or contingency during the cause of production. From the foregoing, a manufacturing system that incorporates production planning in its operations will be more efficient, effective, and economical as compared with those that did not

Antibody response to a Babesia bigemina rhoptry-associated protein 1 surface-exposed and neutralization-sensitive epitope in immune cattle

Protective immunity against Babesia bigemina is hypothesized to involve antibodies directed against merozoite surface-exposed epitopes. Levels of antibody against a rhoptry-associated protein 1 (RAP-1) B-lymphocyte epitope, defined by surface-reactive and inhibitory monoclonal antibodies, in immune cattle sera were determined. All cattle produced antibodies to the epitope; however, there was limited correlation between immune protection induced by infection or RAP-1 immunization and the level of antibody to the neutralization-sensitive B-lymphocyte epitope examined

Cerebral blood flow responses to dorsal and ventral STN DBS correlate with gait and balance responses in Parkinson's disease

Objectives - The effects of subthalamic nucleus (STN) deep brain stimulation (DBS) on gait and balance vary and the underlying mechanisms remain unclear. DBS location may alter motor benefit due to anatomical heterogeneity in STN. The purposes of this study were to (1) compare the effects of DBS of dorsal (D-STN) versus ventral (V-STN) regions on gait, balance and regional cerebral blood flow (rCBF) and (2) examine the relationships between changes in rCBF and changes in gait and balance induced by D-STN or V-STN DBS. Methods - We used a validated atlas registration to locate and stimulate through electrode contacts in D-STN and V-STN regions of 37 people with Parkinson's disease. In a within-subjects, double-blind and counterbalanced design controlled for DBS settings, we measured PET rCBF responses in a priori regions of interest and quantified gait and balance during DBS Off, unilateral D-STN DBS and unilateral V-STN DBS. Results - DBS of either site increased stride length without producing significant group-level changes in gait velocity, cadence or balance. Both sites increased rCBF in subcortical regions and produced variable changes in cortical and cerebellar regions. DBS-induced changes in gait velocity are related to premotor cortex rCBF changes during V-STN DBS (r = − 0.40, p = 0.03) and to rCBF changes in the cerebellum anterior lobe during D-STN DBS (r = − 0.43, p = 0.02). Conclusions - DBS-induced changes in gait corresponded to rCBF responses in selected cortical and cerebellar regions. These relationships differed during D-STN versus V-STN DBS, suggesting DBS acts through distinct neuronal pathways dependent on DBS location

Images and text files for the above publication

This is a 7-zip (https://www.7-zip.org/) containing the files described in the README file. These files include the atlas-space location of all active contacts, the changes in UPDRS, cognitive and visual analog scale measures with stimulation at each contact, and the statistical images described in the manuscript, in NIFTI format

Table S2 from Mapping movement, mood, motivation and mentation in the subthalamic nucleus

Statistical summary of 3D analyses excluding participants who received < 2.5V STN DBS

Table S3 from Mapping movement, mood, motivation and mentation in the subthalamic nucleus

Instructions and anchor points for visual analogue scale ratings