1,544 research outputs found
Analysis of Phenomenon at Quantum Capacitance Limit of SNWFET using FETToy
In The proposed paper several interesting phenomenon that happens at Quantum Conductance Limit (QCL) like transconductance of One Dimensional-Silicon Nano Wire Field Effect Transistor (1D-SNWFET), mobile electron density and injection velocity is studied and simulated using Fettoy simulation tool. The selected gate material in silicon nanowire field effect transistor is SiO2 with K=3.9 and HFO2 with K=20. A coaxial SNWFET is simulated and the results illustrate the essential physics and peculiarities of 1D nanowire FETs, such as the saturation of channel conductance at full degenerate limit and the saturation of transconductance at the quantum capacitance limit and the full degenerate limit
Biocompatibility and Physiological Thiolytic Degradability of Radically Made Thioester-Functional Copolymers: Opportunities for Drug Release
Being nondegradable, vinyl polymers have limited biomedical applicability. Unfortunately, backbone esters incorporated through conventional radical ring-opening methods do not undergo appreciable abiotic hydrolysis under physiologically relevant conditions. Here, PEG acrylate and di(ethylene glycol) acrylamide-based copolymers containing backbone thioesters were prepared through the radical ring-opening copolymerization of the thionolactone dibenzo[c,e]oxepin-5(7H)-thione. The thioesters degraded fully in the presence of 10 mM cysteine at pH 7.4, with the mechanism presumed to involve an irreversible SâN switch. Degradations with N-acetylcysteine and glutathione were reversible through the thiolâthioester exchange polycondensation of RâSC(âO)âpolymerâSH fragments with full degradation relying on an increased thiolate/thioester ratio. Treatment with 10 mM glutathione at pH 7.2 (mimicking intracellular conditions) triggered an insolubleâsoluble switch of a temperature-responsive copolymer at 37 °C and the release of encapsulated Nile Red (as a drug model) from core-degradable diblock copolymer micelles. Copolymers and their cysteinolytic degradation products were found to be noncytotoxic, making thioester backbone-functional polymers promising for drug delivery applications
The Methods to Improve Quality of Service by Accounting Secure Parameters
A solution to the problem of ensuring quality of service, providing a greater
number of services with higher efficiency taking into account network security
is proposed. In this paper, experiments were conducted to analyze the effect of
self-similarity and attacks on the quality of service parameters. Method of
buffering and control of channel capacity and calculating of routing cost
method in the network, which take into account the parameters of traffic
multifractality and the probability of detecting attacks in telecommunications
networks were proposed. The both proposed methods accounting the given
restrictions on the delay time and the number of lost packets for every type
quality of service traffic. During simulation the parameters of transmitted
traffic (self-similarity, intensity) and the parameters of network (current
channel load, node buffer size) were changed and the maximum allowable load of
network was determined. The results of analysis show that occurrence of
overload when transmitting traffic over a switched channel associated with
multifractal traffic characteristics and presence of attack. It was shown that
proposed methods can reduce the lost data and improve the efficiency of network
resources.Comment: 10 pages, 1 figure, 1 equation, 1 table. arXiv admin note: text
overlap with arXiv:1904.0520
The complexities of electronic services implementation and institutionalisation in the public sector
This is the post-print version of the final paper published in Information & Management. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 Elsevier B.V.Electronic service implementation (ESI) in the public sector attempts to improve efficiency, effectiveness, and transparency of governmental departments. Despite having provided the necessary infrastructure and investment, many governments have struggled to realise such aims due to the various forces that challenge implementation and institutionalisation. Using institutional theory as a lens, we explored the forces influencing the implementation and institutionalisation of ESI in the public sector. While our results reinforced previous research in IT implementation and organisational transformation, they showed that the dynamic nature of technology poses unanticipated pressures, and that these can impede the implementation and institutionalisation process
Reducing Inequality â The Missing MDG: A Content Review of PRSPs and Bilateral Donor Policy Statements
Although important gains have been made in reducing global poverty, the pace of progress across the world is not on track to achieve the 2015 MDG targets. Is this due to lack of ownership on the part of national governments and the international community? This article examines whether the Poverty Reduction Strategy Papers (PRSPs) and donor policy statements are aligned with MDG priorities and targets. The analysis found a high degree of commitment to MDGs as a whole but both PRSPs and donor statements are selective, consistently emphasising income poverty and social investments for education, health and water but not other targets concerned with empowerment and inclusion of the most vulnerable such as gender violence or women's political representation. The article concludes that a new, ninth Goal needs to be added â to reduce inequality â to make the MDGs aligned to the original purpose of the Millennium Declaration
REDD+ policy design and policy learning:The emergence of an integrated landscape approach in Vietnam
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The construction of mental health as a technological problem in India
This paper points to an underexplored relationship of reinforcement between processes of quantification and digitization in the construction of mental health as amenable to technological intervention, in India. Increasingly, technology is used to collect mental health data, to diagnose mental health problems, and as a route of mental health intervention and clinical management. At the same time, mental health has become recognized as a new public health priority in India, and within national and global public health agendas. We explore two sites of the technological problematisation of mental health in India: a large-scale survey calculating prevalence, and a smartphone app to manage stress. We show how digital technology is deployed both to frame a âneedâ for, and to implement, mental health interventions. We then trace the epistemologies and colonial histories of âpsyâ technologies, which question assumptions of digital empowerment and of top-down âwesternâ imposition. Our findings show that in India such technologies work both to discipline and liberate users. The paper aims to encourage global debate inclusive of those positioned inside and outside of the âblack boxâ of mental health technology and data production, and to contribute to shaping a future research agenda that analyzes quantification and digitization as key drivers in global advocacy to make mental health count
Warm Sitz Bath: Are There Benefits after Transurethral Resection of the Prostate?
PURPOSE: We aimed to evaluate the efficacy of warm water sitz baths in patients who have undergone transurethral resection of the prostate (TURP) owing to lower urinary tract symptoms secondary to benign prostatic hyperplasia. MATERIALS AND METHODS: We reviewed the records of 1,783 patients who had undergone TURP between 2001 and 2009. In the warm water sitz bath group, patients were instructed to sit in a tub containing lukewarm water at 40-45degrees C for 10 minutes each time. Patients were advised to perform the procedure for at least 5 days immediately after the removal of a Foley urethral catheter. The differences in post-TURP complications between the warm water sitz bath group and the no sitz bath group were compared. RESULTS: After TURP, 359 of the 1,561 patients performed a warm water sitz bath. Complications after TURP, such as hemorrhage, urinary tract infection, urethral stricture, and acute urinary retention were found in 19 (5.3%) and 75 (6.2%) patients in the sitz bath and no sitz bath groups, respectively (p=0.09). There was a significant difference in postoperative complications such as urethral stricture between the warm sitz bath group and the no sitz bath group (p=0.04). The group that did not undergo warm water sitz bath treatment showed a 1.13-fold increased risk of rehospitalization within 1 month after TURP due to postoperative complications compared with the warm water sitz bath group (odds ratio [OR]=1.134; 95% confidence interval [CI], 1.022 to 1.193; p=0.06). CONCLUSIONS: Warm water sitz bath treatment reduced postoperative complications such as urethral stricture. These results suggest that large-scale prospective studies are needed to establish an ideal method and optimal duration of sitz baths.ope
How Should MDG Implementation Be Measured: Faster Progress or Meeting Targets?
This paper questions the methodology that is widely used to assess progress in implementing the Millennium Development Goals (MDGs), a methodology that asks whether the targets are likely to be met. This approach is inappropriate, since the MDGs were neither designed as nor intended to be planning targets. They were political commitments, made by world leaders, that define priorities in a normative framework and that can be used as benchmarks in evaluating progress. In this framework the appropriate question is whether more is being done to live up to that commitment, resulting in faster progress. We present a methodology and analysis using this new framework, and find that our assessment of progress differs considerably from that arising from the conventional methodology. For example, while access to safe water is touted as an MDG success, only a third of the countries improved at a faster rate. Overall, in most indicators and in most countries, progress has not accelerated
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