82 research outputs found
Properties of Concrete Containing Rubber Aggregate Derived From Discarded Tires
This study carried out the experiment to evaluate the effects of different contents and sizes of rubber particles derived from discarded tires used for replacing fine and coarse natural aggregates, on the workability of fresh rubberized concrete and the compressive and flexural strengths of hardened rubberized concrete. The study results showed that the workability of fresh rubberized concrete was improved when replacing natural fine aggregate (sand) with fine rubber particles (2.5-5 mm) at the replacing proportions of 30-50% by volume, and when replacing natural coarse aggregate (crushed stone) with coarse rubber particles (5-20 mm) at the replacing proportions of 10-30% by volume. With respect to the mechanical properties of hardened rubberized concrete, a larger reduction in the compressive and flexural strengths was generally found when the replacing proportions increased and when coarse aggregate rather than fine aggregate was replaced by rubber particles at all replacing proportions (10-50%). However, the study results also indicated that using fine rubber particles for replacing fine natural aggregate at the low replacing proportion (up to 10%) might not cause the significant effect on the compressive and flexural strength of rubberized concrete
Hopf algebras and alternating multiple zeta values in positive characteristic
In \cite{IKLNDP23} we presented a systematic study of algebra structures of
multiple zeta values in positive characteristic introduced by Thakur as
analogues of classical multiple zeta values of Euler. In this paper we
construct algebra and Hopf algebra structures of alternating multiple zeta
values introduced by Harada, extending our previous work. Our results could be
considered as an analogue of those of Hoffman \cite{Hof00} and Racinet
\cite{Rac02} in the classical setting. The proof is based on two new
ingredients: the first one is a direct and explicit construction of the shuffle
Hopf algebra structure, and the second one is the notion of horizontal maps.Comment: 37 pages. arXiv admin note: text overlap with arXiv:2301.0590
An investigation of online teaching and lecturers' online teaching competence in Vietnam: A case study at universities of technology and education
The rapid digital transformation and the widespread influence of the COVID-19 pandemic have impacted higher education in Vietnam. This social setting fosters online teaching and lecturers’ online teaching competencies. The aim of this study is to investigate online teaching competence at two universities of technology and education in Vietnam through a survey. Based on a review of the literature, an online teaching competence scale for lecturers was developed and its validity and reliability were evaluated using exploratory component analysis and Cronbach's alpha coefficients with data from 311 lecturers at two public universities of technology and education. The online teaching competency scale for lecturers consists of 25 items organized into five component competencies: “Understanding student learning”, “online session administration”, “digital content development and learning facilitation”, “technology” and “online learning outcomes assessment”. With the exception of “technology”, the remaining component competencies were identified as good. Not only online teaching modes but also online teaching activities and productions were also deployed to maintain learning activities especially during the COVID-19 pandemic at two universities. Recommendations for developing lecturers' online teaching competence were also considered
Research to support and inform the development, implementation and/or evaluation of tobacco control policies in relation to the framework convention on tobacco control in low and middle-income countries
In order to enforce policies on tobacco control in Vietnam, reliable information on health and socio-economic hazards associated with tobacco farming is needed. The study investigates the harmful impact of tobacco cultivation and processing on health of tobacco farmers in a rural community in northern Vietnam. Objectives included estimation of health care costs as well as health beliefs related to tobacco cultivation and processing. The health of those who cultivate the crop is constantly put in peril. The study confirms that tobacco farming does not bring prosperity to the farmers while causing them a lot of health problems, especially among women
Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection.
BACKGROUND: Most insights into the cascade of immune events after acute respiratory syncytial virus (RSV) infection have been obtained from animal experiments or in vitro models. METHODS: In this study, we investigated host gene expression profiles in nasopharyngeal (NP) swabs and whole blood samples during natural RSV and rhinovirus (hRV) infection (acute versus early recovery phase) in 83 hospitalized patients <2 years old with lower respiratory tract infections. RESULTS: Respiratory syncytial virus infection induced strong and persistent innate immune responses including interferon signaling and pathways related to chemokine/cytokine signaling in both compartments. Interferon-α/β, NOTCH1 signaling pathways and potential biomarkers HIST1H4E, IL7R, ISG15 in NP samples, or BCL6, HIST2H2AC, CCNA1 in blood are leading pathways and hub genes that were associated with both RSV load and severity. The observed RSV-induced gene expression patterns did not differ significantly in NP swab and blood specimens. In contrast, hRV infection did not as strongly induce expression of innate immunity pathways, and significant differences were observed between NP swab and blood specimens. CONCLUSIONS: We conclude that RSV induced strong and persistent innate immune responses and that RSV severity may be related to development of T follicular helper cells and antiviral inflammatory sequelae derived from high activation of BCL6
An Outbreak of Severe Infections with Community-Acquired MRSA Carrying the Panton-Valentine Leukocidin Following Vaccination
Background: Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging
worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination.
Methods and Findings: We carried out a field investigation after adverse events following immunization (AEFI) were reported. We reviewed the clinical data from all cases. S. aureus recovered from skin infections and from nasal and throat swabs were analyzed by pulse-field gel electrophoresis, multi locus sequence typing, PCR and microarray. In May 2006, nine children presented with AEFI, ranging from fatal toxic shock syndrome, necrotizing soft tissue infection, purulent abscesses, to fever
with rash. All had received a vaccination injection in different health centres in one District of Ho Chi Minh City. Eight children had been vaccinated by the same health care worker (HCW). Deficiencies in vaccine quality, storage practices, or preparation and delivery were not found. Infection control practices were insufficient. CA-MRSA was cultured in four children and from nasal and throat swabs from the HCW. Strains from children and HCW were indistinguishable. All carried the Panton-Valentine leukocidine (PVL), the staphylococcal enterotoxin B gene, the gene complex for staphylococcal-cassette-chromosome mec type V, and were sequence type 59. Strain HCM3A is epidemiologically unrelated to a strain of ST59 prevalent in the USA, althoughthey belong to the same lineage.
Conclusions. We describe an outbreak of infections with CA-MRSA in children, transmitted by an asymptomatic colonized HCW during immunization injection. Consistent adherence to injection practice guidelines is needed to prevent CA-MRSA transmission in both in- and outpatient settings
Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial
Background
Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population.
Methods
AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921.
Findings
Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months.
Interpretation
Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke
Secure beamforming for max-min SINR in multi-cell SWIPT systems
© 2016 IEEE. We consider the downlink of a dense multicell network where each cell region is divided into two zones. The users nearby their serving base station (BS) in the inner zone implement simultaneous wireless information and power transfer (SWIPT), thus harvest energy and decode information using the power splitting approach. Further, they try to eavesdrop the information intended for other users within the same cell. The users in the outer zone of each cell only implement information decoding. Our objective is to maximize the minimum user equipment (UE) signal-To-interference-And-noise ratio (SINR) under constraints on the BS transmit power, minimum energy harvesting levels of near-by users, and maximum SINR of eavesdroppers in the presence of multi-cell interference. For such a highly non-convex problem, semidefinite relaxation (SDR) may even fail to locate a feasible solution. We propose two methods to address such a difficult problem. In the spectral optimization, we express the rank-one constraints as a single reverse convex nonsmooth constraint and incorporate it into the optimization objective. In the difference-of-convex-functions iteration method, we directly solve for the beamforming vectors via quadratic programming (QP), avoiding the matrix rank constraints. In each iteration of the proposed algorithms, we only solve one simple convex semidefinite program (SDP) or QP. Our simulation results confirm that the proposed algorithms converge quickly after a few iterations. More importantly, our algorithms yield the performance that is very close to the theoretical bound given by SDP relaxation with comparable computational complexity
Path-Following Algorithms for Beamforming and Signal Splitting in RF Energy Harvesting Networks
© 2016 IEEE. We consider the joint design of transmit beamforming and receive signal-splitting ratios in the downlink of a wireless network with simultaneous radio frequency information and energy transfer. Under constraints on the signal-to-interference-plus-noise ratio at each user and the total transmit power at the base station, the design objective is to maximize either the sum harvested energy or the minimum harvested energy. We develop a computationally efficient path-following method to solve these challenging nonconvex optimization problems. We mathematically show that the proposed algorithms iteratively progress and converge to locally optimal solutions. Simulation results further show that these locally optimal solutions are the same as the globally optimal solutions for the considered practical network settings
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