13 research outputs found
Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry
- Author
- Abdelsayed A.A. (Abeer Abeer)
- Acosta A. (Adriana)
- Adams H. (Heath)
- Agostinho J. (João)
- Agostoni P. (Piergiuseppe)
- Airò E. (Edoardo)
- Al Dalaan A. (Abdullah)
- Alexandre M. (Myriam)
- Alexeeva D.E. (Dalyana Eduardovna)
- Alfetlawi M. (Monthir)
- Almagro R.M. (Raúl Menor)
- Alonso L.P. (Lecue Pilar)
- Altraja A. (Alan)
- Andreassen A.K. (Arne K.)
- Anton L. (Ly)
- Argiento P. (Paola)
- Arjona J.J. (Josefa Jiménez)
- Asencio I. (Isabel)
- Atas H. (Halil)
- Avdeev S.N. (Sergey Nikolaevich)
- Avilés F.F. (Francisco Fernandez)
- Badagliacca R. (Roberto)
- Baptista R. (Rui)
- Barberá J.A. (Joan A.)
- Barry L. (Lisa)
- Bartfay S.-E. (Sven-Erik)
- Batalina M.V. (Marina Vadimovna)
- Bauleo C. (Carolina)
- Blanco I. (Isabel)
- Bohacekova M. (Marcela)
- Boogaard H. (H.)
- Boomars K.A.T. (Karin)
- Boonstra A. (Anco)
- Bosio M. (Martin)
- Bruno N. (Noemi)
- Bukatova I.F. (Irina Fedorovna)
- Camacho R.C. (Rafael Conde)
- Campo F. (Felipe)
- Caneva J. (Jorge)
- Capinha M. (Marta)
- Cardoso T. (Tania)
- Castro G. (Graça)
- Cheng C.-C. (Chin-Chang)
- Chu C.Y. (Chun Yuan)
- Church C. (Colin)
- Cifrián Martínez J.M. (José Manuel)
- Conte L. (Luca)
- Correra A. (Anna)
- Corris P. (Paul)
- Costa S. (Serena)
- Cottin V. (Vincent)
- Coutinho D. (Daniel)
- Cresci C. (Chiara)
- Cuesta V.M. (Victor Mora)
- Cárdenas S.L. (Salvador López)
- D'Alto M. (Michele)
- D'Armini A.M. (Andrea Maria)
- De La Pava S. (Sebastian)
- De Luca A. (Anna)
- De Pauw M. (Michel)
- Delcroix M. (Marion)
- Deleo S. (Sabino)
- Di Marco G.M. (Giovanni Maria)
- Diez M. (Mirta)
- Dwyer N. (Nathan)
- Egenlauf B. (Benjamin)
- Elias T. (Teresa)
- Escribano Subías P. (Pilar)
- Espinha M. (Mafalda)
- Evrard P. (Patrick)
- Ewert R. (Ralf)
- Fanaridis M. (Michail)
- Farina S. (Stefania)
- Farkasova I. (Iveta)
- Farruggio S. (Silvia)
- Feenstra J. (John)
- Feistmantl L.-T. (Lisa-Theresa)
- Fernandez D.I. (David Iturbe)
- Filippov E.V. (Evgeny Vladimirovich)
- Fong M.-C. (Man-Cai)
- Gaine S. (Sean)
- Galgano G. (Giuseppe)
- Gall H. (Henning)
- Galyavich A.S. (Albert Sarvatovich)
- Garcea A. (Alessio)
- Garcia A. (Alberto)
- Garcia P. (Paula)
- García S.A. (Salvador Alcaraz)
- Gasche-Soccal P. (Paola)
- Georgopoulos D. (Dimitrios)
- Gerhardt F. (Felix)
- Ghofrani H.A.
- Giannakoulas G. (George)
- Gomez Sanchez M.-A. (Miguel-Angel)
- Gomez J.E. (Juan Esteban)
- Grazioli V. (Valentina)
- Grimminger J. (Jan)
- Gruenberger M. (Margarethe)
- Grünig E. (Ekkehard)
- Guiot J. (Julien)
- Halank M. (Michael)
- Hanta I. (Ismail)
- Harbaum L. (Lars)
- Hegya D.V. (Daria Viktorovna)
- Helmersen D.S. (Douglas S.)
- Ho W.-J. (Wan-Jing)
- Hoeper M.M. (Marius M.)
- Hsu C.-H. (Chih-Hsin)
- Hsu P.-C. (Po-Chao)
- Hsu T.-S. (Tsu-Shiu)
- Huang C.-L. (Chien-Lung)
- Huang W.-C. (Wei-Chun)
- Huang W.-P. (Wen-Pin)
- Huber C. (Charlotte)
- Humbert M.
- Hung C.-S. (Chi-Sheng)
- Ivanov K.I. (Kyundyul Ivanovich)
- Jansa P. (Pavel)
- Jara L. (Luis)
- Karvounis H.I.
- Keogh A. (Anne)
- Klose H. (Hans)
- Klotsche J. (Jens)
- Knoop-Busch S. (Susanne)
- Kolomeytseva T.M. (Tatyana Mikhaylovna)
- Konstantinides S. (Stavros)
- Kotlyar E. (Eugene)
- Kotsia A. (Anna)
- Kramer T. (Tilmann)
- Kulka C. (Christine)
- Kuo P.-H. (Ping-Hung)
- Kuo S.-H. (Shu-Hung)
- Lador F. (Frédéric)
- Lai W.-T. (Wen-Ter)
- Lang I. (Irene)
- Lange T.J. (Tobias J.)
- Langleben D. (David)
- Lavender M. (Melanie)
- Lema C. (Camila)
- Lin J.-L. (Jiunn-Lee)
- Lin T.-H. (Tsung-Hsien)
- Lin Y.-H. (Yen-Hung)
- Lombardi F. (Francesco)
- Londoño A. (Alejandro)
- Lopez M. (Manuel)
- Lopez R. (Raquel)
- Louis R. (Renaud)
- Loureiro M.J. (Maria José)
- Lunardi C. (Claudio)
- Löffler-Ragg J. (Judith)
- Mackenzie M. (Michele)
- Mager J. (J.)
- Maldonado L. (Lorena)
- Manzi G. (Giovanna)
- Marinho A. (António)
- Marrero F.L. (Fernando León)
- Martinez W. (William)
- Martinez-Meñaca A. (Amaya)
- Martins Jesus S.M. (Susana Maria)
- Martynyuk T.V. (Tamila Vitalievna)
- Massola G. (Giulia)
- Mehta S. (Sanjay)
- Meier C. (Christian)
- Melatini L. (Luciano)
- Mellemkjaer S. (Soren)
- Michalis L.K. (Lampros)
- Mielniczuk L.M. (Lisa M.)
- Minson R. (Robert)
- Mitrouska I. (Ioanna)
- Mouratoglou S. (Sofia)
- Mulè M. (Massimiliano)
- Mutlu B. (Bülent)
- Naldi M. (Marco)
- Ndreu R. (Rudina)
- Newnham M. (Michael)
- Ng B. (Benjamin)
- Nielsen-Kudsk J.E. (Jens Erik)
- Nikolaevich B.A. (Bykov Aleksander)
- Nolde A. (Anna)
- Noël-Savina E. (Elise)
- Okumus G. (Gulfer)
- Oliveira A. (Ana)
- Olzik I. (Ilona)
- Ongen G. (Gul)
- Oqueka T. (Tim)
- Orozco-Levi M. (Mauricio)
- Otero R. (Remedios)
- Paciocco G. (Giuseppe)
- Pane F. (Federico)
- Pappas A. (Athanasios)
- Pappas K. (Konstantinos)
- Pavlickova I. (Ivana)
- Pavlova O.B. (Olga Borisovna)
- Peacock A. (Andrew)
- Pepke-Zaba J. (Joanna)
- Pesci A. (Alberto)
- Petruzzi M. (Mario)
- Peñate G.P. (Gregorio Pérez)
- Picariello C. (Claudio)
- Piccari L. (Lucilla)
- Pin M. (Maurizio)
- Pitsiou G. (Georgia)
- Pittrow D. (David)
- Platonov D.Y. (Dmitry Yurievich)
- Poscia R. (Roberto)
- Prediletto R. (Renato)
- Proudman S. (Susanna)
- Quezada C.A. (Carlos Andres)
- Reesink H.J. (Herre)
- Reeves G. (Glenn)
- Regotta S. (Sabine)
- Repolho D. (Débora)
- Rocha A. (Andreia)
- Rochat T. (Thierry)
- Rodríguez P.V. (Patricia Villanueva)
- Roman A. (Antonio)
- Roncon L. (Loris)
- Rosenkranz S. (Stephan)
- Rozas S.F. (Sonia Fernandez)
- Rundqvist B. (Bengt)
- Sadushi-Kolici R. (Roela)
- Sakkijha H. (Hussam)
- Saleemi S. (Sarferaz)
- Sardella L. (Luca)
- Schulz C. (Christian)
- Schwarz E.I. (Esther Irene)
- Sciortino A. (Antonio)
- Sebastian L. (Laura)
- Shearman N. (Nicole)
- Shiang T. (Teresa)
- Simon M. (Marcel)
- Simonneau G. (Gérald)
- Sitbon O. (Olivier)
- Skripkina E.S. (Elena Sergeevna)
- Snijder R.
- Sourla E. (Evdokia)
- Sousa J. (Joana)
- Speich R. (Rudolf)
- Stanopoulos I. (Ioannis)
- Steele P. (Peter)
- Steringer-Mascherbauer R. (Regina)
- Stevens W. (Wendy)
- Su H.-M. (Ho-Ming)
- Sung S.-H. (Shih-Hsien)
- Söderberg S. (Stefan)
- Talavera M.L. (Maria Lujan)
- Tania G. (Gonçalves)
- Tayler S. (Susanne)
- Tilea I. (Ioana)
- Toorn L.M. (Leon) van den
- Torricelli E. (Elena)
- Toshner M. (Mark)
- Tovar P.P. (Patricia Parada)
- Tregubova A.V. (Anna Viktorovna)
- Tsangaris I. (Iraklis)
- Tsareva N.A. (Natalia Anatolievna)
- Tuhay G. (Graciela)
- Têtu L. (Laurent)
- Ulrich S. (Silvia)
- Un Z. (Zeynep)
- Vachiéry J.-L. (Jean-Luc)
- Valkovicova T. (Tatiana)
- Vannucchi V. (Vieri)
- Vasankari T. (Tuija)
- Vihinen T. (Tapani)
- Vizza C.D. (Carmine Dario)
- Vonk Noordegraaf A. (Anton)
- Voon W.-C. (Wen-Chol)
- Vulcano N. (Norberto)
- Wang W.-H. (Wen-Hwa)
- Weheba I. (Ihab)
- Williams E. (Evgenia)
- Wirtz G. (Gil)
- Wirtz H. (Hubert)
- Wodlin P. (Peter)
- Wu C.-K. (Cho-Kai)
- Wu S.-H. (Shu-Hao)
- Yakovleva O.E. (Olga Eduardovna)
- Yen H.-W. (Hsueh-Wei)
- Yih-Jer Wu J. (Jacob)
- Yotti R. (Raquel)
- Zvereva T.N. (Tatyana Nikolaevna)
- Šimková I. (Iveta)
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2021
- Field of study
Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase
Antioxidant activity of hydrolysates and peptide fractions of glutelin from cocoa (Theobroma cacao L.) seed
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2017
- Field of study
La fracción de glutelina de la almendra de cacao se hidrolizó con alcalasa para la producción de hidrolizados, los cuales se fraccionaron por ultrafiltración para obtener péptidos con un peso molecular (MW) menor a 3000 Da. La actividad antioxidante (AOX) de los hidrolizados y péptidos se evaluó mediante los ensayos de 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2´-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+) y capacidad de absorción del radical oxígeno (ORAC). La fracción peptídica obtenida por ultrafiltración con la mayor AOX se purificó por cromatografía de exclusión molecular, mediante la cual se identificaron cuatro principales picos con un MW entre 535 y 2959 Da. La fracción peptídica P1 (MW = 2959 Da) mostró la mayor actividad reductora de radicales DPPH• y ABTS•+ con valores EC50 de 237.48 y 19.29 µg/mL, respectivamente, los cuales fueron similares a los obtenidos con glutatión. Estos resultados muestran que el tratamiento enzimático de glutelina de cacao es un bioproceso atractivo para la producción de fracciones peptídicas con AOX, que podrían incluirse en el diseño de alimentos funcionales. Además, proporcionaría un uso alternativo del cacao.Glutelin fraction from cocoa almond was hydrolyzed with alcalase for the production of hydrolysates. These were then fractionated by ultrafiltration to obtain peptides with a molecular weight (MW) lower than 3000 Da. The antioxidant activity (AOX) of the hydrolysates and peptides was assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2´-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), and oxygen radical absorbance capacity (ORAC) assays. Ultrafiltered peptide fraction with the highest AOX was purified by size exclusion chromatography, by which four main peaks were identified with a MW between 535 and 2959 Da. The peptide fraction P1 (MW = 2959 Da) showed the highest capacity to scavenge DPPH• and ABTS•+ radicals with radical scavenging activity DPPH• and ABTS•+ with EC50 values of 237.48 and 19.29 µg/mL, respectively, which were similar to those obtained with glutathione. These results show that enzymatic treatment of cocoa glutelin comprises an attractive bioprocess for the production of peptide fractions with AOX, which could be included in the design of functional foods; moreover, they show an alternative use of cocoa
Antioxidant activity of hydrolysates and peptide fractions of glutelin from cocoa ( Theobroma cacao
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Quantum Reality in the Selective Reduction of a Benzofuran System
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 01/05/2019
- Field of study
Two 2,3-disubstituted benzofurans (1 and 2), analogs of gamma-aminobutyric acid (GABA), were synthesized to obtain their 2,3-dihydro derivatives from the Pd/C-driven catalytic reduction of the double bond in the furanoid ring. The synthesis produced surprising by-products. Therefore, theoretical calculations of global and local reactivity were performed based on Pearson’s hard and soft acids and bases (HSAB) principle to understand the regioselectivity that occurred in the reduction of the olefinic carbons of the compounds. Local electrophilicity (ωk) was the most useful parameter for explaining the selectivity of the polar reactions. This local parameter was defined with the condensed Fukui function and redefined with the electrophilic (Pk+) Parr function. The similar patterns of both resulting sets of values helped to demonstrate the electrophilic behavior (soft acid) of the olefinic carbons in these compounds. The theoretical calculations, nuclear magnetic resonance, and resonance hybrids showed the moieties in each compound that are most susceptible to reduction
Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study
- Author
- A A Essam
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled AbdRabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewer
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd El-Sameea
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Alkhatib
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Said Badr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat Pektaş
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
- Akinlabi Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de León
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
- Ali Khan Niazi
- Ali Mussad
- Aliaksandr Filatau
- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
- Aline Broch
- Alissa Gübeli
- Alistair Rocke
- Aliyu Ndajiwo
- Alphonse Zeta Mutabazi
- Alvaro Enrique Mendoza Beleño
- Alvin Ee Zhiun Cheah
- Aly Abd-Elrazek
- Aly Sanad
- Alyaa Halim Elgendy
- Amal Ibrahim
- Amany Eldosouky Mohammed
- Amar Kourdouli
- Amgad Al Meligy
- Amina Abdelhamid
- Aminah Hanum Haji Abdul Majid
- Aminu Mohammad
- Amir Ait Kaci
- Amira Elsawy
- Amira Hassan Bekhet
- Amira Reda
- Amjad Abu Qumbos
- Amjad Elmashala
- Ammar Gado
- Amna Mamdouh Mohamed
- Amna Mohamed
- Amr Ahmed Saleh
- Amr Hassaan
- Amr Hossameldin
- Amreen Faruq
- Amro Aglan
- Ana Lucia Contreras-Vergara
- Ana Maria Sandoval Barrantes
- Anahita Mansuri
- Anan Rady Abdelazeam
- Anass Majbar
- Anastasios Stefanopoulos
- Anders Thorell
- Andre L Mihaljevic
- Andre Navarro
- Andrea Armellini
- Andrea Belli
- Andrea Bondurri
- Andrea Craus-Miguel
- Andrea Natili
- Andrea Ruzzenente
- Andrea Simioni
- Andreass Haloho
- Andrejus Subocius
- Andrew Kirby
- Andrey Litvin
- Andrius Burmistrovas
- Angel David Pérez Rojas
- Angela Dell
- Angela Mazzella
- Angelica Genoveva Vergara Mejia
- Angeline Charles
- Angelo Antoniozzi
- Angelo Benevento
- Angelos Tselos
- Anil Kaul
- Anil Semiz
- Ankur Bhatnagar
- Anmar Homeida
- Anna Jeffery
- Anna Lasek
- Anna Maffioli
- Anna Rinaldi
- Anna Verbeek
- Annalisa Lo Conte
- Annamaria Bigaran
- Annisa Dewi Fitriana Mukin
- Antanas Gulbinas
- Antanas Zadoroznas
- Anthonius Santoso Rulie
- Anthony Ajiboye
- Anthony Avoka
- Anthony Chuk-Him Lai
- Anthony Davor
- Anthony Sander
- Antoinette Bediako-Bowan
- Antonella La Brocca
- Antonio Nocito
- Antonio Picardo
- Antonio Ramos-De la Medina
- Antonio Taddei
- Anwar Atiyeh
- Anyomih Theophilus Teddy Kojo
- April Camilla Roslani
- Aram Abdelhaq
- Arazzelly Del Pilar Paucar
- Arcangelo Picciariello
- Arestis Sokratous
- Arezo Kanani
- Ari Leppäniemi
- Ariadne L'Heveder
- Arianna Birindelli
- Arij Ibrahim
- Arjun Paramasivan
- Arlindawati Suyadi
- Armando José Román Velásquez
- Arnav Agarwal
- Aroub Alkaaki
- Arturas Vaicius
- Arvin Khamajeet
- Arvo Reinsoo
- Arwa Abouzaid
- Arwa Elfarargy
- Arwa Ibrahim
- Arwa Mohamed
- Asad Choudhry
- Asaf Kedar
- Asdaq Ahmed
- Aseel Alnusairat
- Aseel Hamarshi
- Aseel Musleh
- Ashish Gupta
- Ashish Minocha
- Ashraf Maghrabi
- Ashrafun Nessa
- Ashrarur Rahman Mitul
- Ashwath Bandi
- Asmaa Rezq
- Asmaa Salah
- Asnel Dorismé
- Aspasia Papailia
- Astrid Leusink
- Ataa Ahmed
- Athanasia Bamicha
- Athar Abbas
- Athirah Zulkifli
- Athula Tennakoon
- Attia Attia
- Audrey Clarissa
- Audrius Dulskas
- Audrius Parseliunas
- Augusto Zani
- Aurel Mironescu
- Aurel Sandu Mironescu
- Aurelien Scalabre
- Aurora Mariani
- Aurore Haffreingue
- Aurore Thollot
- Awais Raza
- Aya Abdelfatah Ibraheem
- Aya Adel Elsharkawy
- Aya El-Sawy
- Aya Firwana
- Aya Hammad
- Aya Mohamed Fathy
- Aya Reda
- Aya Yehia Ata
- Ayah Hamdan
- Ayat Hassaan
- Ayman And Taher
- Ayman Salman
- Ayman Shwky
- Azher Herebat
- Babajide Adenekan
- Babatunde Odeyemi
- Badr Eldin Adel
- Badreldin Adel Tawfik
- Bahadir Emre Baki
- Bahar Busra Ozkan
- Bakeer Mohamed
- Basant Kumar
- Bashir Bello
- Basma Mahmoud
- Basmah Alhassan
- Bassant Mowafy
- Beatrice Brunoni
- Behrad Barmayehvar
- Belen Sanchez
- Benogreît Parmentier
- Berk Baris Ozmen
- Berna Buse Kobal
- Bernard Limoges
- Bernhard Wolf
- Bertrand Dousset
- Besmir Grizhja
- Bettina Lieske
- Betty Maillot
- Bogdan Diaconescu
- Britta Dedekind
- Bruno Noukpozounkou
- Busra Murutoglu
- Bárbara Málaga
- Calogero Iacono
- Calvin Eng
- Cameron Fairfield
- Camila Sanchez Samaniego
- Camilla Cona
- Can Adiyaman
- Carla Soldevila-Verdeguer
- Carlo Corbellini
- Carlos Nsengiyumva
- Carlos Paz Galvez
- Carly Bisset
- Carmen Capito
- Carmen Fernández
- Carmen García Bernardo
- Carmina Diaz Zorrilla
- Carolina Guzmán Dueñas
- Caroluce K Musyoka
- Catherine A Shaw
- Catrin Jones
- Catrin Morgan
- Cecile Muller
- Cecilia Costa
- Cedar Andress
- Celeste Caliman
- Celeste Del Basso
- Cesar Miranda
- Cesar Razuri
- Cezar Ciubotaru
- Chali Chibuye
- Challine Alexandre
- Charlene Tan
- Charles Dally
- Chaymae Benyaiche
- Cheewei Gan
- Chelise Currow
- Chelsea Deane
- Chetan Khatri
- Chi Chung Foo
- Chi Ying Jacquelyn Fok
- Chia Kong
- Chimwemwe Kwatiwani
- Chingwan Yip
- Chloe Roy
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- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45 center dot 1%) children were from high HDI, 397 (34 center dot 2%) from middle HDI and 239 (20 center dot 6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12 center dot 8% (51/397) in middle HDI and 24 center dot 7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.Peer reviewe
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
- Aanei Carmen M
- Abid Muhammad Bilal
- Abramowitz Matthew K
- Abu-Zaid Ahmed
- Adamo Vincenzo
- Adeyemo Adebolajo A
- Afnan Masoud
- Agarabi Cyrus
- Aggelidou Maria
- Ahmad Haroon
- Ahmad Rafi
- Aizat Wan M
- Ajani Penelope A
- Akinwumi Sayo A
- Al-Farha Abd A
- Al-Lawama Manar
- Al-Owaifeer Adi M
- Al-Riyami Arwa Z
- Alanio Alexandre
- Alaux Cedric
- Albery Gregory F
- Albiol Joan
- Albrecht Dirk R
- Albuquerque Lucia G
- Alhowimel Ahmed
- Ali Junaid
- Alimba C G
- Allardyce Judith
- Almeida Gabriel M F
- Alonso-Caneiro David
- Alper Ozgul M
- Alshehri Mansour
- Alsuhaibani Mohammed
- Alzghari Saeed K
- Amer Said E D R
- Amiya Eisuke
- Ammerman Brooke A
- Amorim Rogerio M
- An Qianli
- Anazodo Udunna C
- Andersen Stig U
- Andersen Vibeke
- Angus Kathryn
- Anikin Andrey
- Aplin John D
- Argyropoulos Christos
- Armitage Charles
- Asaduzzaman Muhammad
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- Ascher David B
- Asefa N G
- Ashry Mohamed
- Asmann Yan W
- Assaeed Abdulaziz M
- Atack John M
- Atanasov Atanas G
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- Gumede Nicksy
- Gumulya Yosephine
- Guo Chengying
- Guo Xinyi
- Guo Yabin
- Gupta Himanshu
- Gurevich Vsevolod V
- Gurney-Champion Oliver J
- Gusev Oleg
- Gutiérrez-Sacristán Alba
- Habes Mohamad
- Hacker Elke
- Hackshaw Allan
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- Hammerschmidt Sven
- Han Hyemin
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- Handfield Martin
- Hanson Jack
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- Hapuarachchi Hapuarachchige C
- Harder Timm
- Hardingham Jennifer E
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- Harrison Pille
- Hartmann Marcus D
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- Hasler David
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- He Shuonan
- Heck Michelle
- Heers Marcel
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- Heijne Marloes
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- Huber Michael
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- Jesus Carlos
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- Jia Husen
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- Jurman Giuseppe
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- K?ra? Nükhet
- Kabra Dhiraj
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- Ohlsson Sophie
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- Ortiz Alberto
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- Oster Henrik
- Ostrikov Kostya
- Otto Siegmar
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- Outeiro Tiago F
- Ouyang Songying
- Owais Mohammed
- O’Mahony Margaret
- O’Toole Ronan
- Pace-Asciak Pia
- Paganoni Sabrina
- Page Andrew
- Pallebage-Gamarallage Menuka
- Palm Christoph
- Palma Jose-Alberto
- Pan Chih-Long
- Pan Zihang
- Panthee Suresh
- Panwar Ajay
- Paradies Yin
- Parchi Piero
- Park Caroline
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- Parsons Jerod R
- Parsons Michael H
- Parsons Nick
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- Patil Chandrashekhar D
- Patterson Chris
- Paul Elisabeth
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- Peckham Michelle
- Pedemonte Nicoletta
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- Peng Xiangda
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- Perco Paul
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- Peres Marco A
- Perry Samuel R
- Peter Jessica
- Peterson Brent M
- Petrelli M
- Pezzuolo Andrea
- Pheko Mpho
- Pianosi Paolo T
- Pichugin Alexander
- Pinto Carlos J C
- Pinto Inês Mendes
- Pinto Karina A
- Pinzi Valentina
- Piotrowski Marcin
- Piovesan Allison
- Plantinga Arnoud
- Plevris John N
- Pluess Michael
- Podolsky Illya M
- Pollesello Piero
- Polz Martin
- Ponti Giovanna
- Popoola Segun I
- Porcelli Piero
- Portilla Maribel
- Portillo M C
- Pourret Olivier
- Pozdnyakov Ilya
- Prajapati Anilkumar S
- Pranata Raymond
- Prescott Julie
- Pridans Clare
- Prieto Daniel
- Prince Martin
- Pritchard Antonia L
- Psaroulaki Anna
- Pujala Ravi Kumar
- Pulia Michael
- Pulido-Arjona Leonardo
- Pullan Wayne
- Pusch Stefan
- Qi Dongchen
- Qi Peng-Fei
- Qi Xingshun
- Qian Siyu
- Qin Lei
- Quinn Gwendolyn P
- Quinn Terence J
- Rafe Ali
- Rafiq Muhammad
- Raghava Gajendra P S
- Rahimi Farid
- Rahman Proton
- Rahman Shaifur
- Raikou Vaia D
- Raman Ayush
- Ramula Satu
- Ranft Andreas
- Raote Ishier
- Rappsilber Juri
- Rassaf Tienush
- Raucher-Chéné Delphine
- Rawski Rafa?
- Ray Asit
- Raza Ali
- Razak Lubna A
- Rebl Henrike
- Reddan Tristan
- Refai Osama
- Refardt Julie
- Regan Tim
- Rehfeldt Florian
- Reiling Jan H
- Remacle Claire
- Reschke Cristina R
- Rezaei Mohsen
- Rhodes Johanna
- Ricciardi Walter
- Richa Tambi
- Richardson Mark F
- Riddick Eric W
- Riess Olaf
- Ritter Uwe
- Riva Giuseppe
- Roach Neil W
- Roberts David D
- Roberts Nicola J
- Robinson K R
- Robles Guillermo
- Rodrigues Tiago
- Rodriguez Cesar
- Roislien Jo
- Roobol Monique J
- Ross Kehinde
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- Rossoni Luca
- Rotge Jean-Yves
- Rouet Romain
- Rovas Alexandros
- Rowe Anna D
- Rowe J Alexandra
- Rudolf Kevin
- Ruepp Andreas
- Rusch Peter
- Rust Petra
- Saad Sonia
- Sabnis Sandeep C
- Sack George H
- Sacks Frank M
- Sadoine Margaux L
- Safaei Soroush
- Saggar Manish
- Saito Yu
- Salama Mohamed F
- Saleh Sherif
- Sallmon Hannes
- Sampson Christopher
- Santos Manuela
- Saudemont Aurore
- Sava Gianni
- Schmidt Axel
- Schmutz Axel
- Schneeberger Pierre H H
- Schrading Simone
- Schramm Alexander
- Schreiber Martin
- Schuele Birgitt
- Schuler Sidney
- Schulte Leon N
- Schuon Robert A
- Schurr Roey
- Schwotzer Daniela
- Schymkowitz Joost
- Sczyrba Alexander
- Searles Stephen
- Sebastian Agata
- Seib Kate L
- Selinski Jennifer
- Seltmann Stefanie
- Senghore Thomas
- Seow Esmond
- Sepanski Robert
- Sergeant Kjell
- Sha Feng
- Shabalin Ivan G
- Shahid Shaouli
- Shalchyan Vahid
- Shalev Nir
- Shang Jin-Long
- Sharma Neeraj
- Sharma Saurab
- Sheehan Barry
- Shen Jun
- Shi Chunhu
- Shi Han-Ping
- Shimada Tomohiro
- Shin Jeon-Soo
- Shirvalkar Prasad
- Shiryayev Oleg
- Shohayeb Belal
- Shortt Colette
- Siebers Robert
- Sillanpää Elina
- Silveyra Patricia
- Singer Josef
- Singh Jugpreet
- Singh Mandeep
- Singh Manisha
- Skinner Debra
- Small Ian
- Smeets Paul A M
- Smith Simon S
- Smith Taylor
- Smout Michael J
- So Po-Wah
- Soares António
- Solano Francisco
- Solomon-Moore Emma
- Sommerlad Andrew
- Sonenshine Daniel E
- Song Chunjiao
- Song Haijun
- Song Jiangning
- Song Lijuan
- Soraggi Samuele
- Sorzano Carlos O
- Southall Tony
- Speakman John R
- Spearman Paul
- Srinivasan Mandyam V
- Srivastava Kshitij
- Srivastava Rupesh K
- St Hilaire Cynthia
- Stabile Laura P
- Staege Martin S
- Stanley Ryan
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- Steadman Kathryn J
- Steckhan Nico
- Stein Nils
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- Stewart Douglas I
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- Storlazzi Curt
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- Strehlow Jan
- Strobl Frederic
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- Subramaniapillai Mehala
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- Sumant Anirudha V
- Summers Mathew J
- Sun Gang
- Sun Jim
- Sun Xianbao
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- Swali Ritu
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- Syme Caitlin
- Szabo Attila
- Szymanski Wiktor
- Sörelius Karl
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- Takeuchi Hisashi
- Tamaian Radu
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- Tan Kok-Hian
- Tanadini-Lang S
- Tanaka Kozo
- Tang Fei
- Tang Haixu
- Tang Jun
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- Tanino Yoshinori
- Tantawy Marwa
- Tao Wanyin
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- Tayebi Mourad
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- Thijs Gert
- Thomas Lisa-Marie
- Thorne Sally
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- Tian Chang F
- Tian Yu-Shi
- Tian Zhiqi
- Tiffon Celine
- Tingting Qian
- Tinnefeld Philip
- Tjahjono Daryono H
- Toelzer Christine
- Tofani Marco
- Tolle Fabrice
- Tomov Nikola
- Tong Xin
- Torga Gonzalo
- Toth Ervin
- Tovar Miguel
- Tran Linh
- Tressoldi Patrizio
- Tripathi Sushil
- Tröder Simon E
- Tsapas Apostolos
- Tsirigotis Konstantinos
- Tuladhar Anil M
- Turak Ayse
- Tuttle Lisa M
- Tuttle Neil
- Tzotzos George
- Uchendu Florence
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- Ukubuiwe Azubuike C
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- Utsumi Toshiaki
- Uversky Vladimir N
- Vaidyanathan Subramanian
- Vaillant Michel
- Valenti Anna
- Valera-Cornejo Diego A
- Valgepea Kaspar
- Valsesia Armand
- van de Mortel Thea
- van den Bos Wouter
- van Dessel Pieter
- van Meerten Tom
- van Nieuwerburgh Filip
- van Raaij Mark J
- van Ruitenbeek Jan
- Vandenbroucke Roosmarijn E
- Vanneste Sven
- Vatanparast Hamid
- Vavvas Demetrios G
- Veiga Feliciano H
- Vendrell Marc
- Verheijen Geert P
- Verloh Niklas
- Verlot Pierre
- Vesk Peter A
- Veys Ralf
- Vickers Paul
- Vickstrom Casey
- Victor Victor M
- Vidal Arnau
- Villemur Richard
- Villet Martin H
- Vindin Howard
- Vitriol Veronica
- Viveiros Miguel
- Vohl Marie-Claude
- Voolstra Christian R
- Vorholt Julia A
- Voskarides Konstantinos
- Voutchkova Denitza D
- Vuillemin Anne
- Wakelin Steven
- Waldron Levi
- Walker Mirella
- Walsh Laurence J
- Wang Amanda Y
- Wang Fang
- Wang Fuan
- Wang Horng-Dar
- Wang Jinhui
- Wang Jiucun
- Wang Jun
- Wang Qing
- Wang Teng
- Wang Xiaomin
- Wang Yun
- Wang Zhenxing
- Watanabe Yoichi
- Watari Ricky
- Waugh Jason
- Webb S A
- Webster Rebecca
- Webster Ruth
- Wei Junnian
- Wei Pan
- Weigert Andreas
- Weinstock Christof
- Welter Danielle
- Wen Jet-Chau
- Werner Gijsbert D A
- Werten Sebastiaan
- Westermair Anna L
- Wham Carol
- White Ethan P
- Wibowo David
- Widera Darius
- Wiener Jan
- Wilharm Gottfried
- Wilkinson Simon
- Williams Brendan A
- Williams Richard
- Willmann Raffaella
- Wilson Alex
- Wilson Coralie
- Wingenbach Tanja S H
- Winslade Matthew
- Wirth Brunhilde
- Wojan Timothy R
- Woldesemayat Adugna A
- Wolff Mathieu
- Wong Alvin
- Wong Bryan M
- Workman Alan D
- Wu Dalei
- Wu Tzu-Wei
- Wu Yi-Rui
- Wuerbel Hanno
- Wyart
- Xavier Rose M
- Xia Wenfeng
- Xiang Tingxiu
- Xiao Han
- Xiao Shumin
- Xiao Xiangshu
- Xie Li-Xin
- Xiong Peng
- Xu Beisi
- Xu Dong
- Xu Haotian
- Xu J W
- Xu Jialin
- Xu Jianping
- Xu Juan
- Xu Jun
- Xu Shicai
- Xu Shilin
- Xu Taosheng
- Xu Ziyue
- Xue Bin
- Xue Yu
- Yadollahpour Ali
- Yalcin Suayib
- Yamato Masayuki
- Yan Hong
- Yang Chongjun
- Yang Dongdong
- Yang En-Cheng
- Yang Hui
- Yang Long
- Yang Mingjun
- Yang Shiqi
- Yang Sunny Y
- Yang Wei
- Yang Yongliang
- Yankilevich Patricio
- Yao Ruifeng
- Yao Wen
- Yassine Abdul-Amir
- Ye Yuzhen
- Ye Zhi-Qiang
- Yeung Andy W K
- Yin Cong-Cong
- Yin Qinan
- Yli-Kauhaluoma Jari
- Yoneyama Hiroshi
- Yoon Jihoon G
- You Yuyi
- Yousefzadeh Abbas
- Yu Chenglong
- Yu Ying
- Yu Yongbo
- Yuan Christina M
- Yuan Guo-Cheng
- Yuh Chiou-Hwa
- Zabetakis Ioannis
- Zaccolo Manuela
- Zaitsu Masayoshi
- Zare Asma
- Zaritsky Arno
- Zaucha Jan
- Zeineb Zian
- Zeng Chen
- Zeng Erliang
- Zeng Zhen
- Zevnik Branko
- Zhan Jian
- Zhan Xiao-Yong
- Zhang Chengrong
- Zhang Chi
- Zhang Chongxing
- Zhang Gong
- Zhang Haowen
- Zhang Jilei
- Zhang Junpeng
- Zhang Kai
- Zhang Li
- Zhang Linxing
- Zhang Rongqiang
- Zhang Tongchuan
- Zhang Tuo
- Zhang Wei
- Zhang Weijia
- Zhang Xianglilan
- Zhang Xiaolei
- Zhang Yao
- Zhang Yi
- Zhang Yingkai
- Zhang Yusen
- Zhang Zhe
- Zhang Zhiyong
- Zhang Zhong-Yin
- Zhang Zhongheng
- Zhao Guoyan
- Zhao Haochen
- Zhao Jing
- Zhao Xin
- Zhao Yuan
- Zheng Shan
- Zhou Bailing
- Zhou Jianyu
- Zhou Kai
- Zhou Min
- Zhou Xiaofan
- Zhou Xiaoyan
- Zhou Yaoqi
- Zhu Dongjie
- Zhu Shu
- Zhu Zhenxing
- Ziegler Andreas
- Zinke Katharina
- Zuberbier Torsten
- Zuckerman Hannah
- Publication venue
- Oxford University Press
- Publication date
- 11/06/2020
- Field of study
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science. © The Author(s) 2019. Published by Oxford University Press
Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries
- Author
- A.A. Essam
- A.B. Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman K.Z. Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B. Hassanein
- Adel Denewar
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adewale Adeniyi
- Adewale O. Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M. Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Saidbadr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W. Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M. Kandil
- Ahmedglal Elnagar
- Ahmet Murat Pektaş
- Aia Mehdi
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- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
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- Alaa El Jamassi
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- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de León
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
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- Alexia Farrugia
- Alexia Farrugia
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- Alfredo Gulielmi
- Ali Ababneh
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- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/09/2023
- Field of study
Background: This study assessed the potential cost-effectiveness of high (80–100%) vs low (21–35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. Methods: Decision-analytic models were constructed using best available evidence sourced from unbundled data of an ongoing pilot trial assessing the effectiveness of high FiO2, published literature, and a cost survey in Nigeria, India, and South Africa. Effectiveness was measured as percentage of SSIs at 30 days after surgery, a healthcare perspective was adopted, and costs were reported in US dollars ().Results:HighFiO2maybecost−effective(cheaperandeffective).InNigeria,theaveragecostforhighFiO2was216 compared with 222forlowFiO2leadingtoa −6 (95% confidence interval [CI]: −13to −1) difference in costs. In India, the average cost for high FiO2 was 184comparedwith195 for low FiO2 leading to a −11(9515 to −6)differenceincosts.InSouthAfrica,theaveragecostforhighFiO2was1164 compared with 1257forlowFiO2leadingtoa −93 (95% CI: −132to −65) difference in costs. The high FiO2 arm had few SSIs, 7.33% compared with 8.38% for low FiO2, leading to a −1.05 (95% CI: −1.14 to −0.90) percentage point reduction in SSIs. Conclusion: High FiO2 could be cost-effective at preventing SSIs in the three countries but further data from large clinical trials are required to confirm this
Use of Telemedicine for Post-discharge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review with Meta-analysis
- Author
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewar
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji Ademuyiwa
- Adesoji Ademuyiwa
- Adesoji O Ademuyiwa
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale Adisa
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Saidbadr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat Pektaş
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
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- Al Faifi Jubran
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- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de León
- Alberto Peón
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
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- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
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- Aliyu Ndajiwo
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- Vu Thanh Hien Le
- Vytautas Gaižauskas
- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong Kuhaendran Gunaseelan
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda Tasneem Idress
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yucel Cengiz Dmitri Raptis
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2022
- Field of study
Objective: This study aimed to determine whether remote wound reviews using telemedicine can be safely upscaled, and if standardised assessment tools are needed. Summary background data: Surgical site infection is the most common complication of surgery worldwide, and frequently occurs after hospital discharge. Evidence to support implementation of telemedicine during postoperative recovery will be an essential component of pandemic recovery. Methods: The primary outcome of this study was surgical site infection reported up to 30-days after surgery (SSI), comparing rates reported using telemedicine (telephone and/or video assessment) to those with in-person review. The first part of this study analysed primary data from an international cohort study of adult patients undergoing abdominal surgery who were discharged from hospital before 30-days after surgery. The second part combined this data with the results of a systematic review to perform a meta-analysis of all available data conducted in accordance with PRIMSA guidelines (PROSPERO:192596). Results: The cohort study included 15,358 patients from 66 countries (8069 high, 4448 middle, 1744 low income). Of these, 6907 (45.0%) were followed up using telemedicine. The SSI rate reported using telemedicine was slightly lower than with in-person follow-up (13.4% vs. 11.1%, P<0.001), which persisted after risk adjustment in a mixed-effects model (adjusted odds ratio: 0.73, 95% confidence interval 0.63-0.84, P<0.001). This association was consistent across sensitivity and subgroup analyses, including a propensity-score matched model. In nine eligible non-randomised studies identified, a pooled mean of 64% of patients underwent telemedicine follow-up. Upon meta-analysis, the SSI rate reported was lower with telemedicine (odds ratio: 0.67, 0.47-0.94) than in-person (reference) follow-up (I2=0.45, P=0.12), although there a high risk of bias in included studies. Conclusions: Use of telemedicine to assess the surgical wound post-discharge is feasible, but risks underreporting of SSI. Standardised tools for remote assessment of SSI must be evaluated and adopted as telemedicine is upscaled globally
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
- Author
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Aflori Laura
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Amri Khalid
- Al Hussaini Sabah
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alias Raja Liza Raja
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angel Miguel Paludi
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Anizi Mashel Al
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Araujo Daniela Marques
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Aribawa Mahaalit Alit
- Arkalaki Eleni
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam M
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azam Ummi Azmira Ahmad
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Baillie Shelley
- Baines Duncan
- Baio Thalissa Hermínia
- Bairaktari Aggeliki
- Baker Gerard
- Baker Katie-Anne
- Baker Paul
- Balain Birender
- Balajonda Naraida
- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
- Balfoussia Danai
- Bali Christina
- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
- Basanth Sujith
- Batchelor Nick
- Bateman Brian
- Bates Alexander
- Bates Sarah
- Batista Hugo Dias
- Bauchmuller Kris
- Bauer Marlene
- Baumgarten Georg
- Baxter Linden
- Beaton Ceri
- Beattie Scott
- Beattie Scott
- Beattie Scott
- Beavis Vanessa
- Beavis Vanessa
- Bechan Sudha
- Beer Johan
- Bejia Tarek
- Belciu Ioana
- Belda Margarita Tormo
- Bell Gillian
- Bell Rachel
- Bell Rachel
- Bell Stephanie
- Bellandi Mattia
- Bello Jibril
- Beloeil Helene
- Belskiy Vladislav
- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benevento Angelo
- Bengeri Sheshagiri
- Bennett Cambell
- Bennett Michael
- Bennett Rachael
- Bennett Victoria
- Bentley Conor
- Beretta Luigi
- Berg Andrew
- Berg Bianca
- Bergin Colin
- Bernard Andre
- Bernard Andre
- Bernard Andre
- Bernat Maria Jose
- Berntsen Emer
- Berntsen Emer
- Bertram Wendy
- Bester Delia
- Bester Marlet
- Bettega Fernanda
- Bettinelli Alessandra
- Bhardwaj Neeraj
- Bhatia Kailash
- Bhula Chettan
- Bi Yanbing
- Biais M.
- Biais Matthieu
- Biais Matthieu
- Biccard Bruce
- Biccard Bruce M
- Bidd Heena
- Bidd Heena
- Bidgoli Jawad
- Biffen Andrew
- Bignami Elena
- Bilolikar Anjali
- Birch Julie
- Bishop David Gray
- Biyase Thuli
- Bizios Christol
- Blackwell Clare
- Blackwood Douglas
- Blaj Mihaela
- Blakemore Stephen P
- Bland Martin
- Blunt Mark
- Blyth Katharine
- Bocchino Speranza
- Bodansky Daniella
- Bodger Phoebe
- Boer Christa
- Boer Hans Donald
- Boereboom Catherine
- Boggiano Victoria
- Bokkel-Andela Janneke
- Bolaji Benjamin
- Bolton David
- Boone Myles
- Boschi Luca
- Boshier Piers
- Botes Marisa
- Botis Ioannis
- Bottini Corrado
- Bottrill Fiona
- Bouchez Stefaan
- Boulton Kerenza
- Bouris Vasilios
- Bourner Lynsey
- Boutsikos Georgios
- Bouwman Arthur
- Bouwman Arthur
- Bowrey Sarah
- Boxall Leigh
- Boyd Christine
- Bradburn Mike
- Bradburn Mike
- Bradley Jacqueline
- Branagan Graham
- Branco Teresa
- Brand Bastiaan
- Brandsborg Birgitte
- Breitenstein Stefan
- Brennan Andrew
- Brennan Emma
- Brenner Laura
- Brincat Maximilian
- Briscoe Richard
- Bristogiannis Sotirios
- Brooke Jenny
- Brookes Jamie
- Brookes Morag
- Brooks Carolyn
- Broomby Rupert
- Brotto Ana Flavia
- Brown Andrew
- Brown Caroline Wrey
- Brown Gemma
- Brown Jamie
- Brown Janette
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- Brown Richard
- Brown Robyn
- Browning Julie
- Bruma Dana
- Brunete Tamara
- Brunswicker Annemarie
- Bryant Helen
- Bua Emmanuel
- Buccimazza Ines
- Buckley Sarah
- Buerkle Christian
- Buhre Wolfgang
- Buhre Wolfgang
- Builu Pierre Monji
- Buise Marc
- Bullock Clare
- Bunwarie Bimalshakth
- Burns Karen
- Burrows Lorna
- Burrows Tom
- Burston Ben
- Burtenshaw Andrew
- Burton Megan
- Busuioc Mihai
- Butryn Izabella
- Butt Georgina
- Byrne Kelly
- Bührer Thomas
- Cabezuelo Estefania
- Cabral Raquel
- Cabrini Luca
- Cacala Sharon
- Cai Fang
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- Camsooksai Julie
- Cancho David
- Candido Keulle
- Cang Jing
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- Cardellino Silvano
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- Carp Cristina Paula
- Carr Adrienne
- Carrera Ronald
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- Carroll Jo
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- Castaño Beatriz
- Castle Gail
- Castro Gabriel Isaac Pereira
- Cavanagh Sarah
- Cawthorn Louise
- Cernea Daniela Denisa
- Chaddock Mark
- Chaloulis Panagiotis
- Chan Alexander
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- Chan Mathew
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- Chan Matthew
- Chan Peter
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- Chan Weng Ken
- Chan Yik Lam
- Chande Shiv
- Chandler Ben
- Chandra Susilo
- Chandra Susilo
- Chandrasekharan Shardha
- Chang Yuan Hsuan
- Chaniotaki Fotini
- Charitos Efthimios
- Charlalampidoy Alexandra
- Charles Rob
- Chatterjee Devnandan
- Chatterjee Jayanta
- Chatzimichali Aikaterini
- Chau Simon
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- Cheah Clarissa
- Cheah Seleen
- Cheeseman Michelle
- Cheing Yushio
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- Chen James
- Chen Junping
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- Chen Lee-lynn
- Chen Linbi
- Chen Liyong
- Chen Pushan
- Chen Qiang
- Chen Rong
- Chen Shasha
- Chen Shiyu
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- Chen Yaqiu
- Chen Yijiao
- Chen Yijun
- Chen Yongjie
- Chen Zhang
- Cheng Baoli
- Cheng Ka Ho
- Cherian Ritchie
- Cherrett Veronica
- Chetty Rubendraj R
- Chew Michelle
- Chew Michelle
- Chhabra Ashok
- Chicken Dennis-Wayne
- Chilinciuc Ion
- Chin Im Im
- Chirkut Subash
- Chlorou Dimitra
- Choi Hyun-min David
- Choi Stephen
- Chow Lorraine
- Christian Rachel
- Christiansen Ida Cecilie
- Christmas Natasha
- Christodoulidis Gregory
- Christodoulopoulou Theodora
- Christofaki Maria
- Christoforidis Dimitri
- Chronis Christos
- Chu Hiu Man
- Chu Susanna
- Chua Pandora
- Chukkambotla Srikanth
- Chung Chun Kwong Eric
- Cifra Elna
- Ciobanu Cristina
- Ciobotaru Oana Roxana
- Cirstea Emanuel
- Clark Richard
- Clarkson Aisling
- Clavien Pierre-Alain
- Claxton Andrew
- Clemmons Karen
- Cloro Luigi Maria
- Clyde Antony
- Cobzaru Isabelle
- Codita Anisoara
- Colangelo Antonio
- Colangelo Chiara
- Colling Kerry
- Collins Michelle
- Collins Nwokoro
- Colvin Carolyn
- Commey Thelma
- Comptaer Nicolas
- Conceição Soares Maria
- Conde Carlos
- Conradie Alae
- Constantin Kathryn
- Cook Tim
- Cooper Lauren
- Cooper Lucy
- Cooper Mariese
- Cooper Richard
- Cooper Sarah
- Copaciu Elena
- Cope Jennifer
- Copley Edward
- Copotoiu Sanda Maria
- Coppens Marc
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- Currow Helen
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- D'Andrea Rocco
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- Dai Qingqing
- Dai Qinxue
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- Daikou Panagoula
- Dalamagka Maria
- Dalampini Eleftheria
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- Damant Rose
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- De Meyer Jenine N
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- Del Valle Santiago Garcia
- Delgado García David R
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- Duca Alejandro
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- Futier Emmanuel
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- Gama N Sibusiso
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- Ganter Michael T
- Gao Hong
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- Gercek Yuksel
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- Gray Catherine
- Gray Sophie
- Greaves K. E.
- Greaves Rosanna
- Green Garyth M
- Green-Thompson Randolph
- Greene Michael
- Gregory Peter
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- Griffiths Ewen
- Grigoras Ioana
- Grigoryev Evgeny
- Grintescu Ioana
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- Grubmueller Karl Gernot
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- Haddow James
- Hadebe Bernard
- Hadfield Daniel
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- Hamzah Zulkarnain
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- Handayani Dini
- Harden Catherine
- Hare Gregory
- Hariharan Vimal
- Harrichandparsad R
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- Harris Benjamin
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- Harsan Cristian Remus
- Hartmann Cristina
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- Hatton Jonathan
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- Hennings Charles
- Hering Jens Peter
- Hernandez Carlos B
- Hernandez Miguel
- Hert Stefan
- Hesketh Sue
- Hewson Russ
- Hewson Russell
- Heyse Bjorn
- Hicks Catherine
- Hidayatullah Rahmat
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- Xiong Xiapei
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- Xu Guan-Jie
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- Yagnik Anmol
- Yan Yixiu
- Yang Jian
- Yang Lu
- Yang Qiuhong
- Yang Shuangjia
- Yang Tianqin
- Yang Yang
- Yao Shanglong
- Yao Yurui
- Yap Huey Ling
- Yarwood Jamie
- Yassaee Arrash
- Ye Haiwang
- Ye Hui
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- Yeh Erlinda
- Yin Ning
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- Yong Johnny
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- Yuan Jing
- Yuan Yazhuo
- Yuliana Annika
- Yun Bai
- Zaane Bas
- Zaimi Donika
- Zakynthinos Spyros
- Zamudio Diana
- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
- Zeggeren Laura
- Zeidan Lisa
- Zeng Qiuting
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Huaigen
- Zhang Huan
- Zhang Jie
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- Zhang Min
- Zhang Mingxiao
- Zhang Qin
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- Zhang Shihai
- Zhang Weiwei
- Zhang Xiaoguang
- Zhang Xiaolin
- Zhang Xiaoyan
- Zhang Yan
- Zhang Yapping
- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zin Nor Hafizah Mohd
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Zundert Tom
- Zyl Rebekka
- åkring Irene
- Ögren Katrin
- Publication venue
- 'Wiley'
- Publication date
- 22/10/2018
- Field of study
Background
The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).
Methods
This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.
Results
A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).
Conclusion
Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
- Author
- Ab Majid Mohd Azuan
- Ab Rahman Ahmad Sufian
- Ab Rahman Rusnah
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abd Ghafar Fara Nur Idayu
- Abd Hadi Husni Zaeem
- Abdel Goad Ehab Helmy
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams David
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A.
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahamed khader null
- Ahmad Azam Ummi Azmira
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Anizi Mashel
- Al hussaini Sabah
- Al'Amri Khalid
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alberto Lisi Zaheer Moolla
- AlbertoVolta Carlo
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alit Mahaalit Aribawa
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Antonina Webombesa
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Arkalaki Eleni
- Arlo whitehouse null
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam F Noorbhai M.
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Bai Yun
- Baillie Shelley
- Baines Duncan
- Baio Thalissa Hermínia
- Bairaktari Aggeliki
- Baker Gerard
- Baker Katie-Anne
- Baker Paul
- Balain Birender
- Balaji Packianathaswamy
- Balajonda Naraida
- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
- Balfoussia Danai
- Bali Christina
- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Baroselli Antonio
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
- Basanth Sujith
- Batchelor Nick
- Bateman Brian
- Bates Alexander
- Bates Sarah
- Batista Hugo Dias
- Bauchmuller Kris
- Bauer Marlene
- Baumgarten Georg
- Baxter Linden
- Beaton Ceri
- Beattie Scott
- Beavis Vanessa
- Beavis Vanessa
- Bechan Sudha
- Bejia Tarek
- Belciu Ioana
- Belda Margarita Tormo
- Bell Gillian
- Bell Rachel
- Bell Stephanie
- Bellandi Mattia
- Bello Jibril
- Beloeil Helene
- Belskiy Vladislav
- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benedikt Preckel Osne Kirzner
- Benevento Angelo
- Bengeri Sheshagiri
- Bennett Cambell
- Bennett Michael
- Bennett Rachael
- Bennett Victoria
- Bentley Conor
- Beretta Luigi
- Berg Andrew
- Bergin Colin
- Bernard Andre
- Bernat Maria Jose
- Berntsen Emer
- Bertram Wendy
- Bester Delia
- Bester Marlet
- Bettega Fernanda
- Bettinelli Alessandra
- Bhardwaj Neeraj
- Bhatia Kailash
- Bhula Chettan
- Bi Yanbing
- Biais Matthieu
- Biccard B. M.
- Biccard Bruce
- Biccard Bruce M.
- Bidd Heena
- Bidgoli Jawad
- Biffen Andrew
- Bignami Elena
- Bilolikar Anjali
- Bin Mustapha Mohd Tarmimi
- Birch Julie
- Bishop David Gray
- Biyase Thuli
- Bizios Christol
- Blackwell Clare
- Blackwood Douglas
- Blaj Mihaela
- Blakemore Stephen P.
- Bland Martin
- Blunt Mark
- Blyth Katharine
- Bocchino Speranza
- Bodansky Daniella
- Bodger Phoebe
- Boer Christa
- Boereboom Catherine
- Boggiano Victoria
- Bogner Gerhard
- Bokkel-Andela Janneke ten
- Bolaji Benjamin
- Bolton David
- Boone Myles
- Boschi Luca
- Boshier Piers
- Botes Marisa
- Botis Ioannis
- Bottini Corrado
- Bottrill Fiona
- Bouchez Stefaan
- Boulton Kerenza
- Bouris Vasilios
- Bourner Lynsey
- Boutsikos Georgios
- Bouwman Arthur
- Bowrey Sarah
- Boxall Leigh
- Boyd Christine
- Bradburn Mike
- Bradley Jacqueline
- Branagan Graham
- Branco Teresa
- Brand Bastiaan
- Brandsborg Birgitte
- Breitenstein Stefan
- Brennan Andrew
- Brennan Emma
- Brenner Laura
- Brincat Maximilian
- Briscoe Richard
- Bristogiannis Sotirios
- Brooke Jenny
- Brookes Jamie
- Brookes Morag
- Brooks Carolyn
- Broomby Rupert
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- Brown Andrew
- Brown Caroline Wrey
- Brown Gemma
- Brown Jamie
- Brown Janette
- Brown Lynne
- Brown Richard
- Brown Robyn
- Browning Julie
- Bruma Dana
- Brunete Tamara
- Brunswicker Annemarie
- Bryant Helen
- Bua Emmanuel
- Buccimazza Ines
- Buckley Sarah
- Buerkle Christian
- Buhre Wolfgang
- Builu Pierre Monji
- Buise Marc
- Bullock Clare
- Bunwarie Bimalshakth
- Burns Karen
- Burrows Lorna
- Burrows Tom
- Burston Ben
- Burtenshaw Andrew
- Burton Megan
- Busuioc Mihai
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- Butt Georgina
- Byrne Kelly
- Bührer Thomas
- Cabezuelo Estefania
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- Cabrini Luca
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- Cai Fang
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- Camsooksai Julie
- Cancho David
- Candido Keulle
- Cang Jing
- Cannavo' Maurizio
- Cao Jianqiao
- Cao Ying
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- Wylie Katharine
- Xia Jiangyan
- Xia Yanfei
- Xia Zhong-yuan
- Xiao Wangpin
- Xiao Wei
- Xie Guohao
- Xie Jue
- Xie Junjie
- Xie Keliang
- Xifara Archontoula
- Xiong Xiapei
- Xiong Yingfen
- Xouplidis Kyriakos
- Xu Guan-Jie
- Xu Lin
- Xu Liyuan
- Xu Qiong
- Xu Shixia
- Xue Rui
- Yagnik Anmol
- Yan Yixiu
- Yang Jian
- Yang Lu
- Yang Qiuhong
- Yang Shuangjia
- Yang Tianqin
- Yang Yang
- Yao Shanglong
- Yao Yurui
- Yap Huey Ling
- Yarwood Jamie
- Yassaee Arrash
- Ye Haiwang
- Ye Hui
- Yegnaram Shashikant
- Yeh Erlinda
- Yin Ning
- Yip Chi Pang
- Yong Johnny
- Yu Hai Chuan
- Yu Shuchun
- Yu Tian
- Yu Yonghao
- Yuan Dajiang
- Yuan Fang
- Yuan Jiaqi
- Yuan Jing
- Yuan Yazhuo
- Yuliana Annika
- Zaimi Donika
- Zakynthinos Spyros
- Zamudio Diana
- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
- Zeidan Lisa
- Zeng Qiuting
- Zerman Luiza
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Hongyan
- Zhang Huaigen
- Zhang Huan
- Zhang Jie
- Zhang Kai
- Zhang Lina
- Zhang Min
- Zhang Mingxiao
- Zhang Qin
- Zhang Ruilin
- Zhang Shihai
- Zhang Weiwei
- Zhang Xiaoguang
- Zhang Xiaolin
- Zhang Xiaoyan
- Zhang Xuekang
- Zhang Yan
- Zhang Yapping
- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Lili
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Xiaoping
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Åkring Irene
- Ögren Katrin
- Publication venue
- Health Sciences Research Commons
- Publication date
- 30/10/2017
- Field of study
© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine