Hydrodynamics and Rheology: Key Factors in Mechanisms of Large Landslides

When checking the behaviour of large landslides, deterministic stability analysis has little sense. Stability coefficients can only be seen as the relationship between acting and reacting forces. In fact, large landslides simply move in any case, more or less quickly. When stable, the displacements are actually so small that they aren\u27t detectable. Thus the so called security factor could always be set to unity, and the computations performed as back analysis. The transition from a very slow viscous displacement to a catastrophic failure is better described in a change of rheological behaviour than in an overtaking of a stability coefficient. Actors of such changes are in most cases the hydrodynamic and hydrogeological conditions, related to external factors such as climatic changes, weathering, natural or artificial deforestation, etc. Two cases located in the south Alps, one in Switzerland and the second in Italy, involving weathered metamorphic rocks are taken as illustrating examples

Exploring the impact of mulberry fruits on metabolic syndrome: a systematic review of current evidence

This is the final version. Available on open access from Elsevier via the DOI in this recordData availability: No data was used for the research described in the article.Background Mulberries are rich in nutrients including a wide range of polyphenols that possess different bioactive properties. This systematic review illustrates mulberry's potential as a promising plant food for mitigating the perturbations associated with metabolic syndrome. Methods A systematic search was conducted on 1st March 2023 in Scopus and PubMed. A total of 15 eligible studies (in vitro and in vivo) studies evaluating the effect of mulberries on metabolic syndrome-related factors such as obesity, diabetes, high cholesterol and high blood pressure were included. Results Predominantly, the studies have centred around its anti-visceral-obesity and lipid-reducing effects. The interventions in these studies spanned 8–12 weeks, employing modest oral doses—ranging from 10 to 800 of mg/kg of body weight per day—of mulberry extracts, powders, or freeze-dried fruits. The favorable effects of mulberry are predominantly ascribed to its rich polyphenolic content, which interacts with diverse metabolic pathways. In terms of its anti-visceral-obesity effect, these polyphenolic compounds, particularly anthocyanins, exhibit the capacity to modulate fatty acid and triglyceride synthesis, enhance mitochondrial function, and attenuate reactive oxygen species accumulation. In vivo, constituents such as resveratrol, rutin, and anthocyanins demonstrate efficacy in inhibiting lipid synthesis, accumulation, and oxidation, leveraging their free radical scavenging ability, while concurrently orchestrating metabolic modulation in tandem with prebiotic agents. Conclusions Based on these data, it can be inferred that the utilization of white mulberry holds greater promise in the management of ailments like hypertension and dyslipidemia. Conversely, black mulberry displays efficacy in addressing diabetes and obesity

The preparation period in basketball: Training load and neuromuscular adaptations

© 2018 Human Kinetics, Inc. Purpose: To investigate the effect of the preparation period on neuromuscular characteristics of 12 professional (PRO) and 16 semiprofessional (SEMIPRO) basketball players and relationships between training-load indices and changes in neuromuscular physical performance. Methods: Before and after the preparation period, players underwent a countermovement jump (CMJ) test followed by a repeated change-of-direction (COD) test consisting of 4 levels with increasing intensities. The peripheral neuromuscular functions of the knee extensors (peak torque [PT]) were measured using electrical stimulations after each level (PT1, PT2, PT3, and PT4). Furthermore, PT Max (the highest value of PT) and PT Dec (PT decrement from PT Max to PT4) were calculated. Results: Trivial to small (effect size [ES] = -0.17 to 0.46) improvements were found in CMJ variables, regardless of competitive level. After the preparation period, peripheral fatigue induced by a COD test was similarly reduced in both PRO (PT Dec: from 27.8% [21.3%] to 11.4% [13.7%]; ES = -0.71; 90% confidence interval [CI], ±0.30) and SEMIPRO (PT Dec: from 26.1% [21.9%] to 10.2% [8.2%]; ES = -0.69; 90% CI, ±0.32). Moderate to large relationships were found between session rating of perceived exertion training load and changes in peak power output (PPO) measured during the CMJs (rs [90% confidence interval]: PPOabs, -.46 [±.26]; PPOrel, -.53 [±.23]) and in some PTs measured during the COD test (PT1, -.45 [±.26]; PT2, -.44 [±.26]; PT3, -.40 [±.27]; and PT Max, -.38 [±.28]). Conclusions: The preparation period induced minimal changes in the CMJ, while the ability to sustain repeated COD efforts was improved. Reaching high session rating of perceived exertion training loads might partially and negatively affect the ability to produce strength and power

Urban food waste for soil amendment? Analysis and characterisation of waste-based compost for soil fertility management in agroecological horticultural production systems in the city of Rosario, Argentina

Urban and peri-urban lands can be an important source of food production for localised and sustainable food systems, however, their soils can be of poor quality, degraded or damaged by anthropic activities, and little is known about their suitability or safety. This paper aims to contribute to this knowledge gap by assessing the soil remediation capacity and qualities of different types of compost made from urban and peri-urban organic wastes for agroecological food production. Prepared over the course of 2021, and used in 2022 for food growing, five different composts were observed and analysed, in two different farms in the city of Rosario, Argentina. Four raw materials generated largely by local industries were used to make the composts: chicken manure, rumen (cow’s stomachs), brewer’s bagasse (byproducts of the beer industry) and urban leaves collected from the municipality waste collection. These were mixed in different proportions (all reaching the 20–30 C/N ratio, typical of quality compost) to produce viable growing substrates where radishes and lettuces were grown. The aim of the study was to assess the possibility, quality and limitations to use locally available organic inputs for soil fertility management in agroecological farming, in the context of urbanisation and to assess pathways to develop closed-cycle agroecological agriculture at metropolitan level. Natural manure substrates (raw and composted) were analysed, as well as crops grown and fertilised with each of the substrates. The attributes and limiting factors of each substrate and their response to local soil conditions were compared and physicochemical, biochemical, and microbiological analyses were performed, including among others, the study of microbial biomass, biological activity, biophytotoxicity, pH, aerobic heterotrophs, nitrogen fixation, and the presence of antibiotics, agrochemicals and heavy metals. The results of the analyses show that all the composted materials improved the physical, chemical and biological properties. However, in some cases, pollutants were present even after composting. Analysis carried out on the vegetables generally indicate undetectable levels or levels below the admissible limits, demonstrating the filtering capacity of the different composts and the soil

Ethnographic understandings of ethnically diverse neighbourhoods to inform urban design practice

The aim of this paper is to inform urban design practice through deeper understanding and analysis of the social dynamics of public outdoor space in ethnically diverse neighbourhoods. We hypothesise that findings from ethnographic research can provide a resource that improves cultural literacy and supports social justice in professional practice. The primary method is a meta-synthesis literature review of 24 ethnographic research papers, all of which explore some dimensions of public open space use and values in UK urban contexts characterised by ethnic and racial diversity. We summarise thematic understandings and significance of neighbourhood places of shared activity, parks, spaces of passing-by and of retreat. We evaluate the implications for intercultural social dynamics, exploring the spatial and temporal dimensions of conviviality and racism in public open space. We then argue that it is possible to develop principles for urban design practice informed by this work, and propose four for discussion: maximising straightforward participation, legitimising diversity of activity, designing in micro-retreats of nearby quietness and addressing structural inequalities of open space provision. We conclude that ethnographic research can provide detailed insights into the use of the public realm and also inform a more nuanced understanding of outdoor sociality relevant for an increasingly diverse society. The challenge is two-fold: for ethnographers to become less cautious in engaging with decisions and priorities regarding how cities change, and for urban designers to explicitly embed informed understandings of difference into their broad desire for inclusive public space

Establishing urban gardens on vacant land while considering international good practices: a legal case study from Portugal

There is a gap in most countries’ legal frameworks regarding their ability to connect vacant land and urban gardens. Hence, research is needed to understand how regulation on vacant land might be designed to promote a more sustainable purpose to it. Urban gardens are a type of urban agriculture that could be potentiated by such regulation. The aim of this paper is to show how that can be done through the Municipal Master Plans (MMP) legal and regulatory framework for the Portuguese case, by reviewing worldwide good practices on vacant land restorations for urban sustainable development. The paper comprises a literature review on good practices adopted in different countries regarding vacant lot restoration. The evaluation of good practices is built on the achievement of the three pillars of sustainability. Five Portuguese MMP were used, as empirical data, to support the design of a new legal and regulatory framework. The goal is to enhance the sustainable destination of vacant land by converting it into urban gardens. The analysis of these MMPs demonstrated that they disregard urban gardens as a tool to promote urban sustainability in spite of global trends to make urban territorial planning and management instruments greener. An additional outcome of this paper is to categorise different types of vacant land in the five municipalities under analysis according to their suitability for urban garden conversion. The design of the legal framework enhancing the conversion of vacant land into urban garden will contribute to the 2030 international agenda goals’ achievement. The proposal would create an innovative legal framework in the case of Portugal that could be replicated by other countries.info:eu-repo/semantics/acceptedVersio

Double blind randomized placebo-controlled trial on the effects of testosterone supplementation in elderly men with moderate to low testosterone levels: design and baseline characteristics [ISRCTN23688581]

In ageing men testosterone levels decline, while cognitive function, muscle and bone mass, sexual hair growth, libido and sexual activity decline and the risk of cardiovascular diseases increase. We set up a double-blind, randomized placebo-controlled trial to investigate the effects of testosterone supplementation on functional mobility, quality of life, body composition, cognitive function, vascular function and risk factors, and bone mineral density in older hypogonadal men. We recruited 237 men with serum testosterone levels below 13.7 nmol/L and ages 60–80 years. They were randomized to either four capsules of 40 mg testosterone undecanoate (TU) or placebo daily for 26 weeks. Primary endpoints are functional mobility and quality of life. Secondary endpoints are body composition, cognitive function, aortic stiffness and cardiovascular risk factors and bone mineral density. Effects on prostate, liver and hematological parameters will be studied with respect to safety. Measure of effect will be the difference in change from baseline visit to final visit between TU and placebo. We will study whether the effect of TU differs across subgroups of baseline waist girth (< 100 cm vs. ≥ 100 cm; testosterone level (<12 versus ≥ 12 nmol/L), age (< median versus ≥ median), and level of outcome under study (< median versus ≥ median). At baseline, mean age, BMI and testosterone levels were 67 years, 27 kg/m(2 )and 10.72 nmol/L, respectively

Sliding channel cladding connections for precast structures subjected to earthquake action

The traditional seismic design of precast frame buildings concerns the calculation of the frame, considering the cladding panels as non-structural added masses without stiffness, assuming they are connected so to not interact with the frame. Under seismic excitation, the cladding connections are subjected to complex multi-directional actions, depending on the panel static scheme, all of which involve relative motion between cladding and structure. The correct kinematics of these connections in decoupling the panels from the structure has rarely been demonstrated, and accidental coupling may result in dangerous sudden increase of forces and subsequent failure of the connections. This is also confirmed by post-earthquake field observations on precast structures, which are characterised by pronounced deformation under seismic loading due to their flexibility. An innovative panel-to-structure sliding connection conceived to allow for an effective cladding-structure decoupling has been tested to check its correct kinematics within a uniaxial test apparatus, imposing displacement histories with application of constant normal force. The experimental results of cyclic tests with a tailored test protocol are presented, and static and dynamic friction coefficients are experimentally evaluated. A cyclic test on a full-scale precast prototype equipped with sliding panel connections has been carried out, checking the global behaviour of such systems and their installation peculiarities. Design rules for the evaluation of seismic actions arising within the proposed panel arrangements are finally provided, accounting for the experimentally evaluated friction coefficients