2,696 research outputs found
Use of Residential Care in Europe for Children Aged Under Three: Some Lessons from Neurobiology
This critical commentary reviews the research into the use of residential care for children aged under three years and looks at some of the explanations that can be found for this in neurobiology. There continue to be high numbers and rates of these vulnerable children in institutions not only in the former Soviet states, but also in Western Europe. The new research provides strong evidence on the negative consequences for these children, particularly for those who remain in institutional care beyond the age of six months. Explanations from neurobiology sit well beside understandings drawn from attachment theory and start to show the mechanisms for this and also the ability of the brain to compensate
Time to move on from the 'love in' with outsourcing and PFI - here's how
Although public bodies invevitably have to make supply decisions that involve third parties, the law must allow them to impose public interest conditions, write John Tizard and David Walker. They explain why outsourcing has so far failed, and what should be done about it
Genome variation and molecular epidemiology of Salmonella enterica serovar Typhimurium pathovariants
Salmonella enterica serovar Typhimurium is one of approximately 2,500 distinct serovars of the genus Salmonella but is exceptional in its wide distribution in the environment, livestock, and wild animals. S. Typhimurium causes a large proportion of nontyphoidal Salmonella (NTS) infections, accounting for a quarter of infections, second only to S. enterica serovar Enteritidis in incidence. S. Typhimurium was once considered the archetypal broad-host-range Salmonella serovar due to its wide distribution in livestock and wild animals, and much of what we know of the interaction of Salmonella with the host comes from research using a small number of laboratory strains of the serovar (LT2, SL1344, and ATCC 14028). But it has become clear that these strains do not reflect the genotypic or phenotypic diversity of S. Typhimurium. Here, we review the epidemiological record of S. Typhimurium and studies of the host-pathogen interactions of diverse strains of S. Typhimurium. We present the concept of distinct pathovariants of S. Typhimurium that exhibit diversity of host range, distribution in the environment, pathogenicity, and risk to food safety. We review recent evidence from whole-genome sequencing that has revealed the extent of genomic diversity of S. Typhimurium pathovariants, the genomic basis of differences in the level of risk to human and animal health, and the molecular epidemiology of prominent strains. An improved understanding of the impact of genome variation of bacterial pathogens on pathogen-host and pathogen-environment interactions has the potential to improve quantitative risk assessment and reveal how new pathogens evolve
Exploring the impact of group work and mentoring for multiple heritage children's self-esteem, well-being and behaviour
Findings are reported from a study of an innovative Multiple Heritage Service in Sheffield (UK) which provides, inter alia, individual mentoring for young people and school-based group sessions on cultural heritage, dealing with racism and enhancing well-being. Groupwork, undertaken between November 2005 and December 2006, was evaluated by a before/after design with 43 children aged from eight to fifteen attending five different groups (response rate 77 per cent), using three well-established and validated measures. There were improvements on the Rosenberg Self-esteem Scale from 31.415 to 33.024 (p =0.005) with more improvement among younger children and boys (p=0.004 and p=0.001); and well-being as measured by the GHQ12 improved from 1.460 to 0.8378 (p=0.111) with more improvement among older children (p=0.026). On the third measure, of problem behaviour (the Strengths and Difficulties Questionnaire) there was an improvement from 12.4 to 12.1 (p=0.716) but there was no improvement at all for girls. Mentoring was evaluated by telephone interviews between June and October 2006 with 14 mothers whose children had just completed, or were nearing completion of, mentoring (response rate 70 per cent). Overall the mothers’ evaluations were highly positive: two-thirds commended the service on the positive impact on their children’s well-being and happiness (including all the mothers of daughters); a half reported positive impacts on identity; mothers commended the positive role model effect same-sex mentors had on their children’s behaviour; but only a third said mentoring had boosted their children’s self-esteem
Citizenship and Learning Disabled People: The Mental Health Charity MIND’s 1970s Campaign in Historical Context
Current policy and practice directed towards people with learning disabilities originates in the deinstitutionalisation processes, civil rights concerns and integrationist philosophies of the 1970s and 1980s. However, historians know little about the specific contexts within which these were mobilised. Although it is rarely acknowledged in the secondary literature, MIND was prominent in campaigning for rights-based services for learning disabled people during this time. This article sets MIND’s campaign within the wider historical context of the organisation’s origins as a main institution of the inter-war mental hygiene movement. The article begins by outlining the mental hygiene movement’s original conceptualisation of ‘mental deficiency’ as the antithesis of the self-sustaining and responsible individuals that it considered the basis of citizenship and mental health. It then traces how this equation became unravelled, in part by the altered conditions under the post-war Welfare State, in part by the mental hygiene movement’s own theorising. The final section describes the reconceptualisation of citizenship that eventually emerged with the collapse of the mental hygiene movement and the emergence of MIND. It shows that representations of MIND’s rights-based campaigning (which have, in any case, focused on mental illness) as individualist, and fundamentally opposed to medicine and psychiatry, are inaccurate. In fact, MIND sought a comprehensive community-based service, integrated with the general health and welfare services and oriented around a reconstruction of learning disabled people’s citizenship rights
What Constitutes Intermarriage for Multiracial People in Britain?
Intermarriage is of great interest to analysts because a group’s tendency to partner across ethnic boundaries is usually seen as a key indicator of the social distance between groups in a multiethnic society. Theories of intermarriage as a key indicator of integration are, however, typically premised upon the union of white and nonwhite individuals, and we know very little about what happens in the unions of multiracial people, who are the children of intermarried couples. What constitutes intermarriage for multiracial people? Do multiracial individuals think that ethnic or racial ancestries are a defining aspect of their relationships with their partners? In this article, I argue that there are no conventions for how we characterize endogamous or exogamous relationships for multiracial people. I then draw on examples of how multiracial people and their partners in Britain regard their relationships with their partners and the significance of their and their partners’ ethnic and racial backgrounds. I argue that partners’ specific ancestries do not necessarily predict the ways in which multiracial individuals regard their partners’ ethnic and racial backgrounds as constituting difference or commonality within their relationships
Use of avian bornavirus isolates to induce proventricular dilatation disease in conures
Avian bornavirus (ABV) is a newly discovered member of the family Bornaviridae that has been associated with the development of a lethal neurologic syndrome in birds, termed proventricular dilatation disease (PDD). We successfully isolated and characterized ABV from the brains of 8 birds with confirmed PDD. One isolate was passed 6 times in duck embryo fibroblasts, and the infected cells were then injected intramuscularly into 2 healthy Patagonian conures (Cyanoliseus patagonis). Clinical PDD developed in both birds by 66 days postinfection. PDD was confirmed by necropsy and histopathologic examination. Reverse transcription–PCR showed that the inoculated ABV was in the brains of the 2 infected birds. A control bird that received uninfected tissue culture cells remained healthy until it was euthanized at 77 days. Necropsy and histopathologic examinations showed no abnormalities; PCR did not indicate ABV in its brain tissues
Shirking and Remaining Years on Players’ Contracts in Major League Baseball
This undergraduate economics thesis is meant to find statistically significant evidence for shirking behavior in Major League Baseball (MLB). Theory suggests that players shirk on effort when they have recently signed a long-term lucrative contract, since there is little incentive to compete when money is guaranteed to the player regardless of current performance. It is particularly important to understand the MLB labor market, since the firms giving out contracts not only have a copious amount of production information regarding their employees, but this data is widely available to the general public. This study will make use of modern sabermetric statistics in order to further open up the conversation regarding shirking with advanced statistics. It will also seek to control for other motivational forces at play, such as intrinsic motivation of the player based on their own self-confidence, as well as extrinsic motivation regarding the performance of the time in terms of win-loss record. Such motivational factors had not yet been discussed within the shirking conversation
An Opposition Commentary
The author, being the MP for Panmure and Labour Associate Spokesperson for Justice, provides a commentary on Rt Hon Justice Hardie Boys' paper, "Judicial Attitudes to Family Property". The author adopts the view of her predecessor Lianne Dalziel and the Labour Women's Council: that the law should recognise the changes in family patterns in New Zealand and should acknowledge the intent of the Human Rights Act 1993 to outlaw discrimination on the basis of marital status and sexual orientation. 
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