474 research outputs found

    Dante and the “Dead White Dude” Dilemma: Exploring the Complexities of Diversity and Controversy in Medieval Literature

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    Recently, one of the goals on the English discipline has been diversification. Students and scholars alike call for program requirements that are inclusive instead of imperialistic. They want to read texts written by non-white, non-male authors and to hear voices that are less represented in literature. In short, they want to eliminate the focus on literature written by the “dead white dude.” While literature programs should be more diversified, it is still possible to hear from marginalized voices and discuss current controversial issues through older canonical texts. Dante Alighieri does this exceptionally well in his Divine Comedy as he tends to diverge from traditional medieval thinking. In Inferno specifically, Dante includes voices from women, same-sex sinners, and cultural Others in order to push back against the oppressive attitudes of his day. Although Dante’s poem does not provide a perfect subversion of medieval attitudes, it does complicate them, giving us space to question not only his characters but also our own society

    Genetics and genomic medicine in Argentina

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    A historical summary of genetics and genomic medicine in Argentina. We go through the achievements and difficulties in the implementation of genetic and genomic services both in academia and health care.Fil: Vishnopolska, Sebastián Alexis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Turjanski, Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Herrera Piñero, Mariana. Banco Nacional de Datos Genéticos; ArgentinaFil: Groisman, Boris. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; ArgentinaFil: Liascovich, Rosa. Red Nacional de Anomalías Congénitas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chiesa, Ana Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; ArgentinaFil: Marti, Marcelo Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentin

    A History and Definition of Green Roof Technology with Recommendations for Future Research

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    Green roof technology has a history that predates the modern era. Many functions of green roofs utilized during human history are analogous to contemporary functions. The justification of the use of green roof technology based on a review of literature shows the multiple and documented benefits that these systems can impart to the urban environment. A case study of the installation of the Southern Illinois University Carbondale green roof, showed the actual process of constructing the system. The maintenance and observation of this system gives firsthand experience. Interviews with green roof professionals allow greater understanding of current research needs. Finally, from these resources, recommendations for future research can be identified. This could ensure cogent direction in future research

    "Millennial Perspectives and Priorities"

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    Prioritizing student voice, this study investigated the perspectives of undergraduate students in relation to their preferences and priorities for how they desired to experience teaching and learning. While not experts, our assumption was that undergraduate students, because of their relatively long experience as students, would be closely in touch with how they preferred to learn. Employing a mixed method, randomly selected students (N=291 of 3,000) completed a brief online survey, and we followed with qualitative focus groups and individual interviews in order to confirm the quantitative data and deepen our understanding of the student perspective. Findings pointed toward particular student preferences and priorities for: teacher behaviors like caring, passion, and enthusiasm, the communication of clear expectations, course alignment between course content taught and tests, a desire for more real-world applications, and active learning opportunities, all of which, in turn, were generally linked by students to their improved attention, intensity of focus, and ability to engage both in the classroom and during homework

    Megadrought and Megadeath in 16th Century Mexico

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    The native population collapse in 16th century Mexico was a demographic catastrophe with one of the highest death rates in history. Recently developed tree-ring evidence has allowed the levels of precipitation to be reconstructed for north central Mexico, adding to the growing body of epidemiologic evidence and indicating that the 1545 and 1576 epidemics of cocoliztli (Nahuatl for "pest”) were indigenous hemorrhagic fevers transmitted by rodent hosts and aggravated by extreme drought conditions

    Dynamic/Jitter Assessment of Multiple Potential HabEx Structural Designs

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    One of the driving structural requirements of the Habitable Exo-Planet (HabEx) telescope is to maintain Line Of Sight (LOS) stability between the Primary Mirror (PM) and Secondary Mirror (SM) of 5 mas. Dynamic analyses of two configurations of a proposed (HabEx) 4 meter off-axis telescope structure were performed to predict effects of jitter on primary/secondary mirror alignment. The dynamic disturbance used as the forcing function was the James Webb Space Telescope reaction wheel assembly vibration emission specification level. The objective of these analyses was to predict "order-of-magnitude" performance for various structural configurations which will roll into efforts to define the HabEx structural design's global architecture. Two variations of the basic architectural design were analyzed. Relative motion between the PM and the SM for each design configuration are reported

    Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis

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    <p>Abstract</p> <p>Background</p> <p>The use of dried blood spots (DBS) samples in genomic workup has been limited by the relative low amounts of genomic DNA (gDNA) they contain. It remains to be proven that whole genome amplified DNA (wgaDNA) from stored DBS samples, constitutes a reliable alternative to gDNA.</p> <p>We wanted to compare melting curves and sequencing results from wgaDNA derived from DBS samples with gDNA derived from whole blood.</p> <p>Methods</p> <p>gDNA was extracted from whole blood obtained from 10 patients with lone atrial fibrillation (mean age 22.3 years). From their newborn DBS samples, stored at -24°C, genomic DNA was extracted and whole-genome amplified in triplicates. Using high resolution melting curve analysis and direct sequencing in both wgaDNA and gDNA samples, all coding regions and adjacent intron regions of the genes <it>SCN5A </it>and <it>KCNA5 </it>were investigated.</p> <p>Results</p> <p>Altered melting curves was present in 85 of wgaDNA samples and 81 of gDNA samples. Sequence analysis identified a total of 31 variants in the 10 wgaDNA samples. The same 31 variants were found in the exact same pattern of samples in the gDNA group. There was no false positive or negative sequence variation in the wgaDNA group.</p> <p>Conclusions</p> <p>The use of DNA amplified in triplicates from DBS samples is reliable and can be used both for high resolution curve melting analysis as well as direct sequence analysis. DBS samples therefore can serve as an alternative to whole blood in sequence analysis.</p
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