2,407 research outputs found

    Q-switched neodymium-doped phosphate glass fibre lasers

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    The operation of a short-pulse, Q-switched, neodymium-doped fiber laser operating at 1.054µm is described experimentally and theoretically. The laser is efficiently pumped with a single-stripe AlGaAs laser diode and emits &gt;1kW pulses. It is seen that due to high gain, short pulses with high energy extraction efficiency can be obtained. The feature of broad emission lines associated with rare-earth-doped glasses is exploited to demonstrate tunable, Q-switched operation over a 40 nm tuning range. <br/

    Vacuum polarization in the spacetime of charged nonlinear black hole

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    Building on general formulas obtained from the approximate renormalized effective action, the approximate stress-energy tensor of the quantized massive scalar field with arbitrary curvature coupling in the spacetime of charged black hole being a solution of coupled equations of nonlinear electrodynamics and general relativity is constructed and analysed. It is shown that in a few limiting cases, the analytical expressions relating obtained tensor to the general renormalized stress-energy tensor evaluated in the geometry of the Reissner-Nordstr\"{o}m black hole could be derived. A detailed numerical analysis with special emphasis put on the minimal coupling is presented and the results are compared with those obtained earlier for the conformally coupled field. Some novel features of the renormalized stress-energy tensor are discussed

    Magnetically Stabilized Luminescent Excitations in Hexagonal Boron Nitride

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    Magnetically stabilized luminescence is observed in hexagonal boron nitride. The luminescence is induced by absorption of cold neutrons and is in the visible region. In the absence of a magnetic field, the photon emission level is observed to decay over several hundred seconds. A fraction of this luminescence can be suppressed if the temperature is T <~ 0.6 K and the magnetic field is B >~ 1.0 T. Subsequent to irradiation and suppression, luminescence can be induced by an increase in T or lowering of B. Possible explanations include stabilization of triplet states or the localization and stabilization of excitons.Comment: 11 pages, 7 figures, to appear in the Journal of Luminescenc

    Vacuum polarization of a scalar field in wormhole spacetimes

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    An analitical approximation of for a scalar field in a static spherically symmetric wormhole spacetime is obtained. The scalar field is assumed to be both massive and massless, with an arbitrary coupling ξ\xi to the scalar curvature, and in a zero temperature vacuum state.Comment: 10 pages, RevTeX, two eps figure

    Reliability and validity of opiate use self-report in a population at high risk for esophageal cancer in Golestan, Iran

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    Objective: To assess the reliability and validity of self-reported opium use in a rural Iranian population at high risk for esophageal cancer in preparation for a large cohort study. Method: 1,057 subjects ages 33 to 84 years were recruited from Gonbad city and three surrounding villages in Golestan province of Iran and completed a questionnaire and provided biological samples. The history and duration of using opium, smoking tobacco, chewing nass, and drinking alcohol were measured by questionnaire in the entire cohort. A subgroup of 130 people was reinterviewed after 2 months to assess reliability. Validity of the opium question was assessed by comparing the questionnaire responses with the presence of codeine and morphine in the urine of 150 selected subjects. Results: Self-reported opiate use is reliable and valid in this population. The reliability of ever opium use and duration of opium use had κ′s of 0.96 and 0.74, respectively. The validity of self-reported opium use was also high. Using urine codeine or morphine as the gold standard for use of opium, self-report had a sensitivity of 0.93 and a specificity of 0.89. Conclusions: The self-reported use of opium can provide a reliable and valid measurement in this population and will be useful for studying associations between opium use and occurrence of esophageal cancer and other diseases

    Non-Equilibrium Electron Transport in Two-Dimensional Nano-Structures Modeled by Green's Functions and the Finite-Element Method

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    We use the effective-mass approximation and the density-functional theory with the local-density approximation for modeling two-dimensional nano-structures connected phase-coherently to two infinite leads. Using the non-equilibrium Green's function method the electron density and the current are calculated under a bias voltage. The problem of solving for the Green's functions numerically is formulated using the finite-element method (FEM). The Green's functions have non-reflecting open boundary conditions to take care of the infinite size of the system. We show how these boundary conditions are formulated in the FEM. The scheme is tested by calculating transmission probabilities for simple model potentials. The potential of the scheme is demonstrated by determining non-linear current-voltage behaviors of resonant tunneling structures.Comment: 13 pages,15 figure

    Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts

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    BACKGROUND: The magnitude of the association between Helicobacter pylori and incidence of gastric cancer is unclear. H pylori infection and the circulating antibody response can be lost with development of cancer; thus retrospective studies are subject to bias resulting from classifi- cation of cases as H pylori negative when they were infected in the past. AIMS: To combine data from all case control studies nested within prospective cohorts to assess more reliably the relative risk of gastric cancer associated with H pylori infection.To investigate variation in relative risk by age, sex, cancer type and subsite, and interval between blood sampling and cancer diagnosis. METHODS: Studies were eligible if blood samples for H pylori serology were collected before diagnosis of gastric cancer in cases. Identified published studies and two unpublished studies were included. Individual subject data were obtained for each. Matched odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated for the association between H pylori and gastric cancer. RESULTS: Twelve studies with 1228 gastric cancer cases were considered. The association with H pylori was restricted to noncardia cancers (OR 3.0; 95% CI 2.3–3.8) and was stronger when blood samples for H pylori serology were collected 10+ years before cancer diagnosis (5.9; 3.4–10.3). H pylori infection was not associated with an altered overall risk of cardia cancer (1.0; 0.7–1.4). CONCLUSIONS: These results suggest that 5.9 is the best estimate of the relative risk of non-cardia cancer associated with H pylori infection and that H pylori does not increase the risk of cardia cancer. They also support the idea that when H pylori status is assessed close to cancer diagnosis, the magnitude of the non-cardia association may be underestimated

    Detector Description and Performance for the First Coincidence Observations between LIGO and GEO

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    For 17 days in August and September 2002, the LIGO and GEO interferometer gravitational wave detectors were operated in coincidence to produce their first data for scientific analysis. Although the detectors were still far from their design sensitivity levels, the data can be used to place better upper limits on the flux of gravitational waves incident on the earth than previous direct measurements. This paper describes the instruments and the data in some detail, as a companion to analysis papers based on the first data.Comment: 41 pages, 9 figures 17 Sept 03: author list amended, minor editorial change

    Variation in PAH-related DNA adduct levels among non-smokers: The role of multiple genetic polymorphisms and nucleotide excision repair phenotype

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    Polycyclic aromatic hydrocarbons (PAHs) likely play a role in many cancers even in never-smokers. We tried to find a model to explain the relationship between variation in PAH-related DNA adduct levels among people with similar exposures, multiple genetic polymorphisms in genes related to metabolic and repair pathways, and nucleotide excision repair (NER) capacity. In 111 randomly selected female never-smokers from the Golestan Cohort Study in Iran, we evaluated 21 SNPs in 14 genes related to xenobiotic metabolism and 12 SNPs in eight DNA repair genes. NER capacity was evaluated by a modified comet assay, and aromatic DNA adduct levels were measured in blood by32P-postlabeling. Multivariable regression models were compared by Akaike's information criterion (AIC). Aromatic DNA adduct levels ranged between 1.7 and 18.6 per 108 nucleotides (mean: 5.8 ± 3.1). DNA adduct level was significantly lower in homozygotes for NAT2 slow alleles and ERCC5 non-risk-allele genotype, and was higher in the MPO homozygote risk-allele genotype. The sum of risk alleles in these genes significantly correlated with the log-adduct level (r = 0.4, p < 0.001). Compared with the environmental model, adding Phase I SNPs and NER capacity provided the best fit, and could explain 17% more of the variation in adduct levels. NER capacity was affected by polymorphisms in the MTHFR and ERCC1 genes. Female non-smokers in this population had PAH-related DNA adduct levels three to four times higher than smokers and occupationally-exposed groups in previous studies, with large inter-individual variation which could best be explained by a combination of Phase I genes and NER capacity. Copyright © 2012 UICC

    A measurement of the tau mass and the first CPT test with tau leptons

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    We measure the mass of the tau lepton to be 1775.1+-1.6(stat)+-1.0(syst.) MeV using tau pairs from Z0 decays. To test CPT invariance we compare the masses of the positively and negatively charged tau leptons. The relative mass difference is found to be smaller than 3.0 10^-3 at the 90% confidence level.Comment: 10 pages, 4 figures, Submitted to Phys. Letts.
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