79 research outputs found

    The Quest to Solve Problems That Don’t Exist: Thought Artifacts in Contemporary Ontology

    Get PDF
    Questions about the nature of reality and consciousness remain unresolved in philosophy today, but not for lack of hypotheses. Ontologies as varied as physicalism, microexperientialism and cosmopsychism enrich the philosophical menu. Each of these ontologies faces a seemingly fundamental problem: under physicalism, for instance, we have the ‘hard problem of consciousness,’ whereas under microexperientialism we have the ‘subject combination problem.’ I argue that these problems are thought artifacts, having no grounding in empirical reality. In a manner akin to semantic paradoxes, they exist only in the internal logico-conceptual structure of their respective ontologies

    Use of Non-Invasive Brain Stimulation in Stroke

    Get PDF

    The Quantum Mitochondrion and Optimal Health

    Get PDF
    A sufficiently complex set of molecules, if subject to perturbation, will self-organise and show emergent behaviour. If such a system can take on information it will become subject to natural selection. This could explain how self-replicating molecules evolved into life and how intelligence arose. A pivotal step in this evolutionary process was of course the emergence of the eukaryote and the advent of the mitochondrion, which both enhanced energy production per cell and increased the ability to process, store and utilise information. Recent research suggest that from its inception life embraced quantum effects such as “tunnelling” and “coherence” while competition and stressful conditions provided a constant driver for natural selection. We believe that the biphasic adaptive response to stress described by hormesis – a process that captures information to enable adaptability, is central to this whole process. Critically, hormesis could improve mitochondrial quantum efficiency, improving the ATP/ROS ratio, while inflammation, which is tightly associated with the aging process, might do the opposite. This all suggests that to achieve optimal health and healthy ageing, one has to sufficiently stress the system to ensure peak mitochondrial function, which itself could reflect selection of optimum efficiency at the quantum level

    Italian guidelines for primary headaches: 2012 revised version

    Get PDF
    The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in adults was published in J Headache Pain 2(Suppl. 1):105–190 (2001). Ten years later, the guideline committee of the Italian Society for the Study of Headaches (SISC) decided it was time to update therapeutic guidelines. A literature search was carried out on Medline database, and all articles on primary headache treatments in English, German, French and Italian published from February 2001 to December 2011 were taken into account. Only randomized controlled trials (RCT) and meta-analyses were analysed for each drug. If RCT were lacking, open studies and case series were also examined. According to the previous edition, four levels of recommendation were defined on the basis of levels of evidence, scientific strength of evidence and clinical effectiveness. Recommendations for symptomatic and prophylactic treatment of migraine and cluster headache were therefore revised with respect to previous 2001 guidelines and a section was dedicated to non-pharmacological treatment. This article reports a summary of the revised version published in extenso in an Italian version

    The Sultan of Byzantium

    No full text

    Book of the Edge by Ece Temelkuran, Deniz Perin

    No full text

    Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders

    Full text link

    AMO Practices, Innovative business strategy and digitalization

    No full text
    Nowadays, many firms use digitalization to be innovative and have competitive advantage. In this master thesis, the influence of different AMO practices on the degree of digitalization and the influence of innovative business strategy is researched, where innovative business strategy is based on two approaches: strategy as objective and strategy as practice. This research has been conducted by Dutch manufacturing companies. The AMO model consists of three constructs: ability, motivation and opportunity. These constructs include a number of practices that can be used in manufacturing companies. Based on theoretical research, these AMO practices were expected to have a positive impact on the degree of digitalization. Also the presumption is made that innovative business strategy has a positive influence into this relationship. To test these hypotheses, a mixed methods study is conducted. The quantitative data derives from the European Manufactory Survey of 2018 and the qualitative data consist of six semi-structured interviews. The results show that there is an overall effect of AMO practices on the degree of digitalization. Quantitative results show that ability, motivation and opportunity enhancing practices have a positive influence on the degree of digitalization, where qualitative research show that ability and opportunity enhancing practices influence the degree of digitalization. Furthermore, the two approaches of innovative business strategy show different results. It seems like that AMO practices have no influence on companies with strategy as objective approach, while by companies with strategy as practice approach, AMO practices do have influence. These findings have not only theoretical implications, but are also useful for managers to implement digitalization. The results of this master thesis together with the recommendations for future research are explained and provided
    corecore