119 research outputs found
Dynamic Analysis of MRE Embedded Sandwich Plate Using FEM
AbstractMagnetorheological elastomers (MRE) are class of smart materials, whose stiffness and damping characteristics can be changed by applying external magnetic field. In this work three layered rectangular plate is considered where top and bottom layers are made up of aluminium layers and middle layer is MRE material to study free vibration characteristics of the system. With help of Lagrange principle and finite element method (FEM), the governing equation of motion is derived. Natural frequencies and modal loss factors of MRE cored sandwich plate is obtained for different core and constraining layer thickness by using modal strain energy method (MSE) for different magnetic fields. This work will find applications in active reduction of vibrations by applying magnetic field
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MBE Growth and Instrumentation
This thesis mainly aims at application of principles of engineering technology in the field of molecular beam epitaxy (MBE). MBE is a versatile technique for growing epitaxial thin films of semiconductors and metals by impinging molecular beams of atoms onto a heated substrate under ultra-high vacuum (UHV) conditions. Here, a LabVIEW® (laboratory virtual instrument engineering workbench) software (National Instruments Corp., http://www.ni.com/legal/termsofuse/unitedstates/usH) program is developed that would form the basis of a real-time control system that would transform MBE into a true-production technology. Growth conditions can be monitored in real-time with the help of reflection high energy electron diffraction (RHEED) technique. The period of one RHEED oscillation corresponds exactly to the growth of one monolayer of atoms of the semiconductor material. The PCI-1409 frame grabber card supplied by National Instruments is used in conjunction with the LabVIEW software to capture the RHEED images and capture the intensity of RHEED oscillations. The intensity values are written to a text file and plotted in the form of a graph. A fast Fourier transform of these oscillations gives the growth rate of the epi-wafer being grown. All the data being captured by the LabVIEW program can be saved to file forming a growth pedigree for future use. Unattended automation can be achieved by designing a control system that monitors the growth in real-time and compares it with the data recorded from the LabVIEW program from the previous growth and adjusts the growth parameters automatically thereby growing accurate device structures
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A CAM-Based, High-Performance Classifier-Scheduler for a Video Network Processor.
Classification and scheduling are key functionalities of a network processor. Network processors are equipped with application specific integrated circuits (ASIC), so that as IP (Internet Protocol) packets arrive, they can be processed directly without using the central processing unit. A new network processor is proposed called the video network processor (VNP) for real time broadcasting of video streams for IP television (IPTV). This thesis explores the challenge in designing a combined classification and scheduling module for a VNP. I propose and design the classifier-scheduler module which will classify and schedule data for VNP. The proposed module discriminates between IP packets and video packets. The video packets are further processed for digital rights management (DRM). IP packets which carry regular traffic will traverse without any modification. Basic architecture of VNP and architecture of classifier-scheduler module based on content addressable memory (CAM) and random access memory (RAM) has been proposed. The module has been designed and simulated in Xilinx 9.1i; is built in ISE simulator with a throughput of 1.79 Mbps and a maximum working frequency of 111.89 MHz at a power dissipation of 33.6mW. The code has been translated and mapped for Spartan and Virtex family of devices
ANALYSIS OF COMPLEX CHROMOSOMAL ABNORMALITIES IN A CASE OF MULTIPLE MYELOMA USING SPECTRAL KARYOTYPING
Objective: It was proposed to determine the chromosomal abnormalities in a 49-year-old male patient with multiple myeloma (MM) employing both conventional and advanced molecular cytogenetic techniques.Methods: GTG-banding and spectral karyotyping (SKY) on fixed metaphases obtained from LPS-stimulated bone marrow cells and interphase fluorescence in situ hybridization (iFISH) on unsorted marrow cells were carried out to identify genetic markers of prognostic significance.Results: The abnormal chromosomes observed through conventional cytogenetics could be resolved with SKY technique. The translocation t(4;14) (p16;q32) indicating FGFR3/IGH fusion and deletion of 13q14.3 was noticed using iFISH. The genetic abnormalities confirmed a poor prognostic outcome in the patient who died within 6 months of diagnosis.Conclusion: This report emphasizes the need for multicolor FISH techniques besides iFISH to resolve complex abnormalities and to identify cryptic aberrations of importance in risk stratification of MM patients
Shaping Demand and Practices to Improve Family Health Outcomes: Findings from a Quantitative Survey, Volume 3: Bihar
This report provides findings of a study undertaken to generate comprehensive information on eight target behaviors that have direct bearing on family health in rural Bihar. Behaviors include: 1) Increasing the proportion of deliveries that occur in a facility and mothers who have access to basic emergency obstetric care; 2) Increasing the proportion of safe deliveries at home; 3) Increasing the uptake of preventive postnatal-care services for newborns and mothers; 4) Increasing the practice of skin-to-skin care/Kangaroo Mother Care for newborns; 5) Increasing the practice of early and exclusive breastfeeding of infants during the first six months of life; 6) Increasing the proportion of children (6–23 months) who receive appropriate complementary feeding; 7) Increasing the uptake of postpartum family planning methods to adequately space births; 8) Increasing the rate of compliance for recommended schedules of child immunization. Objectives were to: assess the present status of each of the behavior targets, identify the key barriers and facilitating factors to the adoption of these health behaviors, suggest how findings could be utilized for developing a BCC comprehensive strategy. This study generated information that could be used to develop a comprehensive communication strategy
A study of localisation in dual-phase high-strength steels under dynamic loading using digital image correlation and FE analysis
Tensile tests were conducted on dual-phase high-strength steel in a
Split-Hopkinson Tension Bar at a strain-rate in the range of 150-600/s and in a
servo-hydraulic testing machine at a strain-rate between 10-3 and 100/s. A
novel specimen design was utilized for the Hopkinson bar tests of this sheet
material. Digital image correlation was used together with high-speed
photography to study strain localisation in the tensile specimens at high rates
of strain. By using digital image correlation, it is possible to obtain
in-plane displacement and strain fields during non-uniform deformation of the
gauge section, and accordingly the strains associated with diffuse and
localised necking may be determined. The full-field measurements in high
strain-rate tests reveal that strain localisation started even before the
maximum load was attained in the specimen. An elasto-viscoplastic constitutive
model is used to predict the observed stress-strain behaviour and strain
localisation for the dual-phase steel. Numerical simulations of dynamic tensile
tests were performed using the non-linear explicit FE code LS-DYNA. Simulations
were done with shell (plane stress) and brick elements. Good correlation
between experiments and numerical predictions was achieved, in terms of
engineering stress-strain behaviour, deformed geometry and strain fields.
However, mesh density plays a role in the localisation of deformation in
numerical simulations, particularly for the shell element analysis
The Role of β-Arrestin Proteins in Organization of Signaling and Regulation of the AT1 Angiotensin Receptor
AT1 angiotensin receptor plays important physiological and pathophysiological roles in the cardiovascular system. Renin-angiotensin system represents a target system for drugs acting at different levels. The main effects of ATR1 stimulation involve activation of Gq proteins and subsequent IP3, DAG, and calcium signaling. It has become evident in recent years that besides the well-known G protein pathways, AT1R also activates a parallel signaling pathway through β-arrestins. β-arrestins were originally described as proteins that desensitize G protein-coupled receptors, but they can also mediate receptor internalization and G protein-independent signaling. AT1R is one of the most studied receptors, which was used to unravel the newly recognized β-arrestin-mediated pathways. β-arrestin-mediated signaling has become one of the most studied topics in recent years in molecular pharmacology and the modulation of these pathways of the AT1R might offer new therapeutic opportunities in the near future. In this paper, we review the recent advances in the field of β-arrestin signaling of the AT1R, emphasizing its role in cardiovascular regulation and heart failure
Design of an Innovative System for Wave Generation in Direct Tension–Compression Split Hopkinson Bar
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