11 research outputs found
Effect of SGLT2 inhibitors on stroke and atrial fibrillation in diabetic kidney disease: Results from the CREDENCE trial and meta-analysis
- Author
- Abdallah J.
- Abdullah R.
- Abejuela Z.
- Abouglila K.
- Abramowitz M.
- Abusnana S.
- Acosta I.
- Agafyina A.
- Aggarwal N.
- Agra J.
- Ahmad N. N. F. N.
- Ahmed F.
- Aiello J.
- Ainsworth P.
- Aizenberg D.
- Akiyama H.
- Akright L.
- Akyea-Djamson A.
- Al-Karadsheh A.
- Alamartine E.
- Alappan R.
- Albisu J. P.
- Ali N.
- Ali Z.
- Alicic R.
- Allison D. C.
- Alonso R. D. V.
- Alva H.
- Alvarisqueta A.
- Amodeo C.
- Andreeva V.
- Angelescu L. M.
- Angelova A.
- Anghel V.
- Antic S.
- Aoki H.
- Aquitania G.
- Arauz-Pacheco C.
- Arcos E.
- Arenales J. A. S.
- Arfeen S.
- Arif A.
- Aronson R.
- Arutchelvam V.
- Arvind M.
- Asano A.
- Atray N.
- Avendano J.
- Avram R. -I.
- Awad A.
- Babikova J.
- Badat A.
- Bajaj H.
- Baker J.
- Bakris G.
- Ballesteros C. G.
- Barbarash O.
- Barna O.
- Barnard M.
- Barnhill P.
- Baron P. F.
- Barranco E.
- Barrera C.
- Barrios C.
- Bartaskova D.
- Bartolacci I.
- Barton P.
- Barysheva O.
- Beacom M.
- Behara V.
- Bellary S.
- Belo D.
- Belobradkova J.
- Bentley-Lewis R.
- Benusova O.
- Berenguer R.
- Berli M. A.
- Bermudez L.
- Bernardo M.
- Bijata-Bronisz R.
- Bilyk S. D.
- Biscoveanu M.
- Bonadonna R.
- Bordonava A.
- Borges J. L. C.
- Borot S.
- Botsyurko V.
- Bowman-Stroud C.
- Brandon D.
- Breedt J.
- Bregman R.
- Brusco O.
- Buganova I.
- Burst V.
- Busch R.
- Busegeanu M. -M.
- Calcaneo J. P.
- Calella P.
- Canaan Y.
- Canani L. H.
- Cannon C. P.
- Canonge R. S.
- Cantero M. C.
- Caringal C.
- Cariou B.
- Carlo A. D.
- Carrillo L. V.
- Cartasegna L. R.
- Casabella T. S.
- Castellanos R. O.
- Castellino P.
- Castro F. C.
- Ceballos R. I. L.
- Cepeda A. V.
- Cercos E.
- Ceriello A.
- Cervera L. F. F.
- Chacra A. R.
- Chae D. -W.
- Chang C. -T.
- Chavez E. T.
- Chen N.
- Chen Q.
- Cherney D.
- Cheung N. W.
- Chilito A.
- Chiovato L.
- Chizhov D.
- Cho Y. M.
- Chouinard G.
- Christensen T.
- Christiano C.
- Christofides E.
- Chuang L. -M.
- Chuateco C.
- Cianni G. D.
- Cif A.
- Cohen K.
- Cohen R.
- Cohen-Stein D.
- Coloma G. C.
- Colombo H.
- Cometa L. V.
- Comia R. S.
- Commendatore V.
- Conway J.
- Cook C.
- Cosma D.
- Cournoyer S.
- Coyne D.
- Crisan C.
- Cruz J. B.
- Csecsei G.
- Csiky B.
- Cuadrado J.
- Culak J.
- Cuneo C. A.
- Cusumano A. M.
- D'Avila D.
- Da Costa F. A. A.
- Da Silva Franco R. J.
- Daboul N.
- Danos P.
- DaRoza G.
- Darwish R.
- Daswani A.
- Davies E.
- Davies M.
- Davies S.
- Dawson A.
- De Almeida R. S.
- De Brito C. M.
- De Carvalho Contieri F. L.
- De Cosmo S.
- De La Fuente R. A. L.
- De Los Rios J. E.
- De Nicola L.
- De Salazar D. I. M.
- De Serres S.
- De Souza P.
- De Souza Portes E.
- De Zeeuw D.
- Deak L.
- Deboni L. M.
- Deck K.
- Del Campo Blanco B. M.
- Del Carmen Gonzalez Colaso P.
- Demian L. D.
- Derosa G.
- Desouza C.
- Dev D.
- Dewan D.
- Dhillon M.
- Diaz J. P. M.
- Dimitrov S.
- Distiller L.
- Djordjevic M.
- Dobronravov V.
- Dohnalova L.
- Douthat W. G.
- Dran R. D.
- Drasnar T.
- Dreval A.
- Droste C.
- Dua S.
- Dube F.
- Dudar I.
- Dudas M.
- Dussol B.
- Dzupina A.
- Dzuponova J.
- Eder F.
- Edwards R.
- El-Shahawy M.
- Elosegui A. M.
- English P.
- Ervin J.
- Escalante T. D.
- Escobedo R. Z.
- Esquenazi A.
- Evans J.
- Faghih M.
- Farias E.
- Farina M. M.
- Faulmann G.
- Fauvel J. -P.
- Felicio J. S.
- Ferariu I. E.
- Ferkl R.
- Fernandez M. F.
- Fernando M. E.
- Filho F. F.
- Filho R. P.
- Finkelstein H.
- Fishbane S.
- Flores F. J.
- Fragale G.
- Franco G. M.
- Frasca G.
- Fraser D.
- Fraser I.
- Fresnedo G. F.
- Fretes J. O.
- Frias J.
- Fuiano G.
- Fulop P.
- Fushtey I.
- Gajardo V. S.
- Galindo-Ramos E.
- Galphin C.
- Gambaro G.
- Gan C. L.
- Gan S.
- Garcia I.
- Garcia N. H.
- Garcia P. A.
- Garibotto G.
- Gastaldi A.
- Gaupsiene E.
- Gelersztein E.
- Genadieva V.
- Genova-Hristova G.
- Ghani R. A.
- Ghazi A.
- Gimeno J. E. J.
- Giorda C.
- Glenny J. A.
- Glinkina I.
- Gnudi L.
- Godlevska O.
- Goldenberg R.
- Golovchenko O.
- Gomes M.
- Gomez O.
- Gonzalez A.
- Gonzalez A. S.
- Gonzalez E.
- Gonzalez J. P.
- Gopalakrishnan N.
- Gorson D.
- Gourdy P.
- Govender R.
- Govender V.
- Gowda A.
- Goycoa C.
- Gracious N.
- Greco B.
- Greloni G. C.
- Grineva E.
- Grubb S.
- Guerrero R. A. A.
- Guinsburg A.
- Gulati R.
- Guldris S. C.
- Gunstone A.
- Gupta A.
- Gupta M.
- Guzman J. R.
- Gyrina O.
- Haase F. P.
- Hachmann J. C. T.
- Halciakova K.
- Hall T.
- Haller H.
- Halmagyi I.
- Hammoud J.
- Hancu N.
- Handelsman S.
- Hanif W.
- Harcsa E.
- Hartman I.
- Hayashida C. Y.
- Henein S.
- Hermida S.
- Hershon K.
- Higuera J. D.
- Hiser D.
- Hissa M. N.
- Hon G.
- Hotlos L.
- Hristozov K.
- Hsia T. -L.
- Hsieh C. -H.
- Hwang S. -J.
- Iglesias J. N.
- Iitsuka T.
- Ilavska A.
- Ismail M.
- Jackson A.
- Jacob R.
- Jaime M.
- Jain D.
- Jamal A.
- Januszewicz A.
- Jardine M. J.
- Jeong I. -K.
- Jerwan-Keim R.
- Jimenez L. E. H.
- Jimeno C.
- Joerg I. E. R.
- Johnson A.
- Johnson D.
- Jorquera J. G. G.
- Joseph F.
- Joshi M.
- Juarez E. T.
- Juncos L. I.
- Junior R. M.
- Jurgens J.
- Kaczmarek B.
- Kadir K. A.
- Kajiyama S.
- Kamenov Z.
- Kaminska A.
- Kashine S.
- Kaupke C.
- Kawada T.
- Kazmirchuk A.
- Keightley G.
- Keitel E.
- Keltai K.
- Kendereski A.
- Keresztesi S.
- Kern E.
- Keshavamurthy C. B.
- Khandwala H.
- Khanna R.
- Khirmanov V.
- Khitan Z.
- Khullar D.
- Kim S.
- Kim S. G.
- Kim Y. H.
- Kiss K.
- Klein A.
- Klokocnikova V.
- Klyver M. I.
- Kodera T.
- Kohara S. K.
- Kolesnyk M.
- Kolmakova E.
- Komisarenko I.
- Kong W. Y.
- Kong Y.
- Kono H.
- Konyves L.
- Kopyt N.
- Koroleva T.
- Korzh O.
- Kossi M. E.
- Koundurdjiev A.
- Kovar R.
- Kovesdy C.
- Koyama K.
- Kozloviene D.
- Kraft F.
- Kravchun N.
- Krishna G.
- Krishnan S.
- Kropp J.
- Krynski F.
- Kumar A.
- Kumar J.
- Kumar N.
- Kumeda Y.
- Kumwenda M.
- Kusnir J.
- Kvitkova L.
- Kwon H. -S.
- Kwon M. J.
- Lalic K.
- Lalic N.
- Lam S. W.
- Lanchiotti P. V.
- Lane W.
- Lastuvka J.
- Latiff G.
- Lawrence M.
- Lazuka L.
- Le Meur Y.
- Lee B. -W.
- Lee J.
- Lee L. Y.
- Lee M. -K.
- Legun O.
- Lehrner L.
- Leiter L.
- Lentz J.
- Levin A.
- Levin A.
- Levinson D.
- Lewis D.
- Li D.
- Li Q.
- Li W.
- Li X.
- Lim S. K.
- Lin C. -C.
- Lin H.
- Lindley R. I.
- Lisboa H. R. K.
- Liss K.
- Liu J.
- Loh C. L.
- Lombard L.
- Lopez M. D.
- Loza O. T. M.
- Lozano F. F.
- Lozano M. A. T.
- Lozanov L.
- Lu W.
- Lu Y. -C.
- Lukac M.
- MacDougall I.
- Maddux A.
- Madej A.
- Madore F.
- Madueno F. J. T.
- Mah P. M.
- Mahaffey K. W.
- Maheshwari H.
- Major L.
- Malaver N.
- Malberti F.
- Mandayam S.
- Mandreoli M.
- Mankovskyy B.
- Mannucci E.
- Manocha A. B.
- Mao H.
- Marar I.
- Marasaev V.
- Marchetta N.
- Margaritov V.
- Marin T. M.
- Martinez F. J. G.
- Martinka E.
- Martynyuk L.
- Maxeiner S.
- Mazur S.
- Mc-Mahon A.
- Mehta B.
- Mele P.
- Melemadathil S.
- Mendoza J. L. A.
- Mendoza M. L.
- Mercadal L. A.
- Mesa J. V.
- Middleton J.
- Mijangos J. H. S.
- Milagres R.
- Mileder M.
- Miyauchi S.
- Mizuyama K.
- Mkrtumyan A.
- Mlodawska-Choluj D.
- Molina H. L.
- Molnar M.
- Montenegro M. A. F.
- Mookadam M.
- Mordujovich J.
- Moreda R.
- Morugova T.
- Mostovoy Y.
- Moustafa M.
- Mucsi J.
- Muirhead N.
- Munoz L. D. A.
- Munteanu M.
- Nagibovich G.
- Nagibovich O.
- Nam M. -S.
- Narayanan M.
- Narvarte J.
- Nassar T.
- Navickas A.
- Neal B.
- Nedogoda S.
- Negru D.
- Neto B. G.
- Neuen B. L.
- Newman G.
- Ng K. S.
- Ngcakani N.
- Nichol B.
- Nicholls K.
- Nicol P.
- Nicolai S.
- Niiya T.
- Nisnisan J.
- Nixon P.
- Nonchev B.
- Noonan P.
- Noronha I.
- Nortje H.
- Nossuli A. K.
- Novoa P. A.
- Nowicki M.
- O'Hare J.
- O'Shaughnessy A.
- Obialo C.
- Ochodnicka Z.
- Oh K. -H.
- Oishi H.
- Olelewe S.
- Oliver M.
- Onaca A. G.
- Oomman A.
- Oosthuizen H.
- Orellana R. A. G.
- Orio S. I.
- Orlowska-Kowalik G.
- Oroszlan T.
- Orsi E.
- Ortiz L. H. G.
- Ory I.
- Osipova I.
- Ota S.
- Otreras F.
- Oviedo A.
- Packham D.
- Padron J.
- Panarotto D.
- Pankhaniya R.
- Papini N. R.
- Paragh G.
- Park C. -Y.
- Park S. -H.
- Parker R.
- Paschen B.
- Pashkovska N.
- Patel D.
- Patel G.
- Patel N.
- Pattzi H. R.
- Pavon H.
- Pella D.
- Penfornis A.
- Pereira M. A.
- Pererva L.
- Perez A.
- Perez C.
- Perez J. M. P.
- Perez J. P.
- Peringat J.
- Perkovic V.
- Perlman A.
- Pertseva T.
- Pesickova S.
- Peterfai E.
- Peterka K.
- Petrica L.
- Petro G.
- Petry T. B. Z.
- Pettis K.
- Pharr W.
- Philip S.
- Phillips A.
- Piatti P.
- Pichette V.
- Pillay-Ramaya L.
- Plassmann G.
- Plaza M. V.
- Polo J. V. S.
- Popa A. R.
- Popenda G.
- Popovic-Radinovic V.
- Portillo C. M.
- Prasad N.
- Proietto J.
- Prozesky H.
- Pumprla J.
- Purighalla R.
- Quesada-Suarez L.
- Rabasa-Lhoret R.
- Raduan R. A.
- Raffaele P.
- Railey M.
- Raju S. B.
- Ramos C. S.
- Ramos J. C.
- Ramtoola S.
- Ranetti A. -E.
- Rangel J. D. G.
- Rangelov R.
- Ranjan R.
- Rao K. S.
- Raskina T.
- Rastogi S.
- Ratnasingam V.
- Reddy J.
- Reddy J.
- Reddy S.
- Ren Y.
- Rendell M.
- Resk J. H.
- Revesz K.
- Rewerska B.
- Rheeder P.
- Rich L.
- Riera M. T.
- Rista L.
- Roberts A.
- Robinson M.
- Roca L. A. R.
- Rocha C. M.
- Rodriguez H.
- Roger S.
- Rosano M. A. R.
- Rosas S.
- Rose L.
- Rosero R.
- Rotter J. R. C.
- Roussel R.
- Ruiz J. E. A. D.
- Rychlik I.
- Saba F.
- Sabbag A. R. N.
- Sahay M.
- Sakakibara T.
- Sala J.
- Salazar M. A.
- Samoylov O.
- Samoylova Y.
- Sanches F. C. C.
- Sanchez S. B. S.
- Sankaram R.
- Sanson P. S.
- Santana S. S. I.
- Santoro D.
- Santos F.
- Santos J. C.
- Santos L. D.
- Saporito W.
- Saraiva J. F. K.
- Sarin R.
- Sasso F. C.
- Saudek F.
- Saulnier P. -J.
- Saxena M.
- Sazonova O.
- Schiavi L. B.
- Schreiman R.
- Schuch T.
- Scott D.
- Scott R.
- Scotton A. S.
- Seeber M.
- Sekkarie M.
- Sennik D.
- Sensenbrenner J.
- Serafinceanu C.
- Serrano A. G.
- Serviddio G.
- Sessa H.
- Shakeel M.
- Shamkhalova M.
- Shanik M.
- Shaw S.
- Sheu W. H. -H.
- Shinkov A.
- Shudim S. S. B.
- Shutemova E.
- Shwartz Y.
- Simon G.
- Simon M. A. Q.
- Singh B.
- Smatanova I.
- Smirnov I.
- Smith S.
- Solomon R.
- Song W.
- Sosa F. E. E.
- Soto M. B.
- Sowinski D.
- Sprague A.
- Spry L.
- Steele A.
- Stella A.
- Stephens J.
- Strzelecka A.
- Suchinda P.
- Sudhakar B.
- Sultan S.
- Sun J.
- Sun L.
- Surampudi P.
- Sussman S.
- Svyshchenko Y.
- Symonds R.
- Takacs R.
- Takai M.
- Tamayo Y Orozco J. A.
- Tan A.
- Tan G.
- Tangri N.
- Temelkova M.
- Terrelonge A.
- Tesar V.
- Thervet E.
- Thome F.
- Thompson M.
- Toarba C.
- Tolentino M.
- Tomashkevych H.
- Tomonaga O.
- Topchii I.
- Torres M. M.
- Torshizi A.
- Trenche S. M.
- Trespalacios F.
- Trevisan R.
- Triana E. H.
- Trippe B.
- Trueba P.
- Tryshchuk N.
- Tsang V.
- Tseluyko V.
- Tsujimoto M.
- Tu P.
- Turatti L. A. A.
- Turner W.
- Twahirwa M.
- Ulla M. R.
- Updegrove J.
- Urbanaviciene E.
- Uriasyev O.
- Valdez M.
- Valenzuela A.
- Valis M.
- Vallejos A.
- Van Buren P.
- Vangel S.
- Vannorsdall M.
- Varghese F.
- Vasas S.
- Vejar M.
- Velasquez-Mieyer P.
- Velichkova E.
- Vencio S. A. C.
- Vengadasalam P.
- Ventrapragada S.
- Vera G. O.
- Vera M. P.
- Veronelli A. M.
- Vila M. A. M.
- Villarino A.
- Villegas I.
- Visco V. E.
- Vizir V.
- Vlasenko M.
- Vorobyev S.
- Vukotic G.
- Vyasam R. C.
- Wada T.
- Wadud K.
- Wahba M.
- Wakasugi M.
- Wakeling J.
- Wakida Y.
- Walker R.
- Wang G.
- Warren M.
- Wassermann A.
- Watanabe T.
- Watson E.
- Watson H.
- Watts R.
- Weiner D.
- Weiner P.
- Welker J.
- Welsh J.
- Wheeler D.
- Williams M.
- Williams S.
- Winocour P.
- Wong A. C.
- Woo V.
- Yakov A.
- Yamada M.
- Yamada S.
- Yanagida K.
- Yanase T.
- Yang J.
- Yao C.
- Yap Y. E.
- Ygpuara M. D. L.
- Yin A.
- Yoon K. H.
- Young S.
- Yu X.
- Yumita W.
- Yupanqui H.
- Yusof M. D. C.
- Zaidman C. J.
- Zalunardo N.
- Zanella M. T.
- Zaniewski-Singh M.
- Zanoli L.
- Zaoui P.
- Zateyshchikova A.
- Zateyshshikov D.
- Zemek S.
- Zhao M.
- Zheng H.
- Zhou Z.
- Zlova T.
- Zsom M.
- Zub L.
- Zykova T.
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND AND PURPOSE: Chronic kidney disease with reduced estimated glomerular filtration rate or elevated albuminuria increases risk for ischemic and hemorrhagic stroke. This study assessed the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on stroke and atrial fibrillation/flutter (AF/AFL) from CREDENCE (Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation) and a meta-Analysis of large cardiovascular outcome trials (CVOTs) of SGLT2i in type 2 diabetes mellitus. METHODS: CREDENCE randomized 4401 participants with type 2 diabetes mellitus and chronic kidney disease to canagliflozin or placebo. Post hoc, we estimated effects on fatal or nonfatal stroke, stroke subtypes, and intermediate markers of stroke risk including AF/AFL. Stroke and AF/AFL data from 3 other completed large CVOTs and CREDENCE were pooled using random-effects meta-Analysis. RESULTS: In CREDENCE, 142 participants experienced a stroke during follow-up (10.9/1000 patient-years with canagliflozin, 14.2/1000 patient-years with placebo; hazard ratio [HR], 0.77 [95% CI, 0.55-1.08]). Effects by stroke subtypes were: ischemic (HR, 0.88 [95% CI, 0.61-1.28]; n=111), hemorrhagic (HR, 0.50 [95% CI, 0.19-1.32]; n=18), and undetermined (HR, 0.54 [95% CI, 0.20-1.46]; n=17). There was no clear effect on AF/AFL (HR, 0.76 [95% CI, 0.53-1.10]; n=115). The overall effects in the 4 CVOTs combined were: Total stroke (HRpooled, 0.96 [95% CI, 0.82-1.12]), ischemic stroke (HRpooled, 1.01 [95% CI, 0.89-1.14]), hemorrhagic stroke (HRpooled, 0.50 [95% CI, 0.30-0.83]), undetermined stroke (HRpooled, 0.86 [95% CI, 0.49-1.51]), and AF/AFL (HRpooled, 0.81 [95% CI, 0.71-0.93]). There was evidence that SGLT2i effects on total stroke varied by baseline estimated glomerular filtration rate (P=0.01), with protection in the lowest estimated glomerular filtration rate (45 mL/min/1.73 m2]) subgroup (HRpooled, 0.50 [95% CI, 0.31-0.79]). CONCLUSIONS: Although we found no clear effect of SGLT2i on total stroke in CREDENCE or across trials combined, there was some evidence of benefit in preventing hemorrhagic stroke and AF/AFL, as well as total stroke for those with lowest estimated glomerular filtration rate. Future research should focus on confirming these data and exploring potential mechanisms
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
- Author
- Abdallah J
- Abdul Ghani R
- Abdul Kadir K
- Abdullah R
- Abejuela Z
- Abouglila K
- Abraham O
- Abrahamsen I
- Abraira Munoz Ld
- Abramowitz M
- Abusnana S
- Accini Mendoza Jl
- Acosta I
- Agafyina A
- Agarwal R
- Agarwal Rajiv
- Aggarwal N
- Agra J
- Ahmed F
- Ahuad Guerrero Ra
- Aiello J
- Ainsworth P
- Aizenberg D
- Akiyama H
- Akright L
- Akyea-Djamson A
- Al-Karadsheh A
- Alamartine E
- Alappan R
- Albisu Jp
- Ali N
- Ali Z
- Alicic R
- Allison Dc
- Alvarez Garcia P
- Alvarisqueta A
- Alves da Costa Fa
- Amerena J
- Amigo A
- Amodeo C
- Andreeva V
- Andreotti Turatti La
- Angelescu Lm
- Angelova A
- Anghel V
- Antic S
- Aoki H
- Aquitania G
- Arauz-Pacheco C
- Arcos E
- Arfeen S
- Arif A
- Aronson R
- Arutchelvam V
- Arvind M
- Asano A
- Asmarats Mercadal L
- Atray N
- August P
- Avendano J
- Avram Ri
- Awad A
- Babikova J
- Badat A
- Bajaj H
- Baker J
- Bakris G
- Bakris George
- Barbarash O
- Barna O
- Barnard M
- Barnhill P
- Barranco E
- Barrera C
- Barrios C
- Bartaskova D
- Bartolacci I
- Barton P
- Barysheva O
- Beacom M
- Behara V
- Bellary S
- Belo D
- Belobradkova J
- Bentley-Lewis R
- Benusova O
- Berenguer R
- Berli Ma
- Bermudez L
- Bernardo M
- Bhushan Rs
- Bijata-Bronisz R
- Bilyk Sd
- Bin Shudim Ss
- Biscoveanu M
- Bompoint Severine
- Bonadonna R
- Bordonava A
- Borot S
- Botsyurko V
- Bowman-Stroud C
- Brandon D
- Breedt J
- Bregman R
- Brenner Barry M
- Brenner Bm
- Brusco O
- Buganova I
- Bull Scott
- Burst V
- Busch R
- Busegeanu Mm
- Calella P
- Camelo Sanches Fc
- Canaan Y
- Canani Lh
- Cannon Christopher P
- Cannon Cp
- Cantero Mc
- Capuano George
- Caringal C
- Cariou B
- Cartasegna Lr
- Castellino P
- Cercos E
- Cereto Castro F
- Ceriello A
- Chacra Ar
- Chae Dw
- Chang Ct
- Chang T
- Chapin L
- Charytan David M
- Charytan Dm
- Che Yusof Md
- Cheifetz A
- Chen E
- Chen N
- Chen Q
- Cherney D 3rd
- Chertow G
- Cheung Nw
- Chilito A
- Chiovato L
- Chizhov D
- Cho Ym
- Chouinard G
- Christensen T
- Christiano C
- Christofides E
- Chu Pei-Ling
- Chuang Lm
- Chuateco C
- Cif A
- Cigarran Guldris S
- Coffee L
- Cohen K
- Cohen R
- Cohen S
- Cohen-Stein D
- Coloma Gc
- Colombo H
- Comia Rs
- Commendatore V
- Conway J
- Cook C
- Correa Rotter Jr
- Cosma D
- Cournoyer S
- Coyne D
- Crisan C
- Cruz Jb
- Csecsei G
- Csiky B
- Cuadrado J
- Culak J
- Cuneo Ca
- Cunha Borges Jl
- Cunha V\ueancio Sa
- Cusumano Am
- D'Avila D
- da Silva Franco Rj
- Daboul N
- Danos P
- Daroza G
- Darwish R
- Daswani A
- David C
- Davies E
- Davies M
- Davies S
- Dawson A
- De Brouwer K
- de Carvalho Contieri Fl
- De Cosmo S
- De Nicola L
- De Serres S
- de Souza Portes E
- de Souza P
- de Zeeuw D
- de Zeeuw Dick
- Deak L
- Deboni Lm
- Deck K
- Deepak D
- Delos Santos L
- Demian Ld
- Derosa G
- Desouza C
- Destree M
- Dev D
- Dhillon M
- Di Carlo A
- Di Cianni G
- Diaz Escalante T
- Diaz Ruiz Jea
- Dimitrov S
- Distiller L
- Distiller L
- Djordjevic M
- Dobronravov V
- Dohnalova L
- Dominquez Lopez M
- Douthat Wg
- Dran Rd
- Drasnar T
- Dreval A
- Droste C
- Dua S
- Dub\ue9 F
- Dudar I
- Dudas M
- Dussol B
- Dzupina A
- Dzuponova J
- Eder F
- Edwards Robert
- Edwin Fm
- Egido de Los Rios J
- El Kossi M
- El-Shahawy M
- Elosegui Am
- English P
- Enriquez Sosa Fe
- Ervin J
- Esquenazi A
- Evans J
- Faghih M
- Farias E
- Faulmann G
- Fauvel Jp
- Ferariu Ie
- Ferkl R
- Fern\ue1ndez Montenegro Ma
- Fernandez Fresnedo G
- Fernandez Mf
- Feuerstein J
- Filho Ff
- Finkelstein H
- Fishbane S
- Flores Lozano F
- Flota Cervera Lf
- Fragale G
- Frasc\ue0 G
- Fraser D
- Fraser I
- Frenk Baron P
- Fretes Jo
- Frias J
- Fuiano G
- Fulcher G
- Fulop P
- Fushtey I
- G\uf3rriz Jl
- Gaglia J
- Galan Serrano A
- Galindo-Ramos E
- Galphin C
- Gambaro G
- Gan Cl
- Gan S
- Garcia Ballesteros C
- Garcia Ortiz Lh
- Garcia I
- Garcia Nh
- Garibotto G
- Gastaldi A
- Gaupsiene E
- Gelersztein E
- Geloneze Neto B
- Genadieva V
- Genova-Hristova G
- George S
- Ghazi A
- Giorda C
- Glenny Ja
- Glinkina I
- Gnudi L
- Godlevska O
- Godoy Jorquera Jg
- Goldenberg R
- Golovchenko O
- Gomes M
- Gomez Rangel Jd
- Gomez O
- Gonzalez Colaso Pdc
- Gonzalez Martinez Fj
- Gonzalez Orellana Ra
- Gonzalez A
- Gonzalez E
- Gonzalez Jp
- Gopalakrishnan N
- Gorelick P
- Gorson D
- Gourdy P
- Govender R
- Govender V
- Gowda A
- Goycoa C
- Goykhman S
- Gracious N
- Greco B
- Greene T
- Greene Tom
- Greloni Gc
- Grineva E
- Grubb S
- Guinsburg A
- Gulati R
- Gunstone A
- Gupta A
- Gupta M
- Gyrina O
- Haase Fp
- Hadjadj S
- Halciakova K
- Hall T
- Haller H
- Halmagyi I
- Hammoud J
- Hancu N
- Handelsman S
- Hanif W
- Hansraj A
- Harcsa E
- Harris R
- Hartman I
- Hawley C
- Heerspink Hiddo J L
- Heerspink Hjl
- Henein S
- Hermida S
- Hernandez Triana E
- Herrera Jimenez Le
- Hershon K
- Hettiarachchi M
- Higuera Jd
- Hillis G
- Hiser D
- Holman R
- Home P
- Hon G
- Hotlos L
- Hristozov K
- Hsia Tl
- Hsieh Ch
- Hudson M
- Hufert K
- Hwang Sj
- Ignjatovic J
- Iitsuka T
- Ilavska A
- Irizar Santana Ss
- Ismail M
- Jackson A
- Jacob R
- Jaffer S
- Jaime M
- Jain D
- Jamal A
- Januszewicz A
- Januzzi J
- Jardine M
- Jardine Meg J
- Jardine Mj
- Jeong Ik
- Jerwan-Keim R
- Jha V
- Ji L
- Jimenez Florez F
- Jimeno C
- Jodar Gimeno Je
- Johnson A
- Johnson D
- Joseph F
- Joshi M
- Juncos Li
- Jurgens J
- Kaczmarek B
- Kajiyama S
- Kamenov Z
- Kaminska A
- Kashine S
- Kasner S
- Kaupke C
- Kawada T
- Kazmirchuk A
- Keightley G
- Keitel E
- Keltai K
- Kendereski A
- Keresztesi S
- Kern E
- Kerr Saraiva Jf
- Keshavamurthy Cb
- Khandwala H
- Khanna R
- Khirmanov V
- Khitan Z
- Khullar D
- Kim S
- Kim Sg
- Kim Yh
- Kiss K
- Kissela B
- Klein A
- Klokocnikova V
- Klyver Mi
- Kodera T
- Kohara Sk
- Koizumi M
- Kolansky D
- Kolesnyk I
- Kolesnyk M
- Kolmakova E
- Komisarenko I
- Kong Wy
- Kong Y
- Kono H
- Konyves L
- Koppolu D
- Kopyt N
- Koroleva T
- Korzh O
- Koundurdjiev A
- Kovar R
- Kovesdy C
- Koyama K
- Kozloviene D
- Kraft F
- Krane V
- Kravchun N
- Krishna G
- Krishnan S
- Kropp J
- Krynski F
- Kumar A
- Kumar J
- Kumar N
- Kumeda Y
- Kumwenda M
- Kurtz Lisboa Hr
- Kusnir J
- Kvitkova L
- Kwon Hs
- Kwon Mj
- Lalic K
- Lalic N
- Lam Sw
- Lanchiotti Pv
- Lane W
- Lastuvka J
- Latiff G
- Laviada Molina H
- Lawrence M
- Lazuka L
- Le Meur Y
- Lee Bw
- Lee J
- Lee Ly
- Lee Mk
- Legun O
- Lehrner L
- Leia C
- Leiter L
- Lentz J
- Leon de la Fuente Ra
- Levin A
- Levin Adeera
- Levinson D
- Lewis D
- Li D
- Li N
- Li W
- Li X
- Lim Sk
- Lim-Abrahan Ma
- Limos A
- Lin Cc
- Lin G
- Lin H
- Lin P
- Lindley R
- Liss K
- Liu J
- Loh Cl
- Lombard L
- Lozanov L
- Lu W
- Lu Yc
- Lukac M
- Luna Ceballos Ri
- Macdougall I
- Maddux A
- Madej A
- Madore F
- Mah Pm
- Mahaffey Kenneth W.
- Mahaffey Kw
- Maheshwari H
- Major L
- Malaver N
- Malberti F
- Malek Marin T
- Mandayam S
- Mandreoli M
- Manisha S
- Mankovskyy B
- Mannucci E
- Manocha Ab
- Mao H
- Marar I
- Marasaev V
- Marchetta N
- Margaritov V
- Martin Del Camp Blanco B
- Martinka E
- Martynyuk L
- Mascaro D
- Maxeiner S
- Mazur S
- Mcguire Dk
- Mcmahon A
- Medina Fari\uf1a M
- Mehta B
- Meininger G
- Meininger Gary
- Mele P
- Middleton J
- Milagres R
- Mileder M
- Miyauchi S
- Mizuyama K
- Mkrtumyan A
- Mlodawska-Choluj D
- Molina de Salazar Di
- Molnar M
- Montenegro Junior R
- Mookadam M
- Morales Franco G
- Morales Portillo C
- Mordujovich J
- Moreda R
- Moreira de Brito C
- Moreira Diaz Jp
- Moreno Loza Ot
- Morren F
- Morugova T
- Mostovoy Y
- Moustafa M
- Mu\uf1oz Lopez Mendoza M
- Mu\uf1oz Torres M
- Mucsi J
- Muirhead N
- Mujica Trenche S
- Munar Vila Ma
- Munteanu M
- Mustieles Rocha C
- Nagibovich G
- Nagibovich O
- Nam Ms
- Narayanan M
- Narvarte J
- Nassar T
- Navickas A
- Nazario Sabbag \uc2r
- Nazzer Hissa M
- Neal B
- Neal Bruce
- Nedogoda S
- Negru D
- Newman G
- Ng Ks
- Ngcakani N
- Nichol B
- Nicholls K
- Nicol P
- Nicolai S
- Nieto Iglesias J
- Niiya T
- Nik Ahmad Nnf
- Nisnisan J
- Nixon P
- Nonchev B
- Noonan P
- Noronha I
- Nortje H
- Nossuli Ak
- Novoa Pa
- Nowicki M
- Nowicki M
- O'Hare J
- O'Shaughnessy A
- Obialo C
- Obrador Vera G
- Obrador G
- Ochodnicka Z
- Oh Kh
- Oishi H
- Olelewe S
- Oliver M
- Onaca Ag
- Oosthuizen H
- Orio Si
- Orlowska-Kowalik G
- Oroszlan T
- Orozco Castellanos R
- Orsi E
- Ory I
- Osipova I
- Ota S
- Otreras F
- Ounadjela S
- Oviedo A
- Packham D
- Padron J
- Panarotto D
- Pankhaniya R
- Pantoja Perez J
- Paragh G
- Parfrey P
- Park Cy
- Park Sh
- Parker R
- Paschen B
- Pashkovska N
- Patel D
- Patel G
- Patel N
- Pavon H
- Pecoits Filho R
- Pecoits-Filho R
- Pella D
- Penfornis A
- Peralta Calcaneo J
- Pereira Ma
- Pererva L
- Perez Vera M
- Perez A
- Perez C
- Peringat J
- Perkovic V
- Perkovic Vlado
- Perlman A
- Pertseva T
- Pesickova S
- Peterfai E
- Peterka K
- Petrica L
- Petro G
- Pettis K
- Pharr W
- Philip S
- Phillips A
- Piatti P
- Pichette V
- Pillay-Ramaya L
- Plassmann G
- Plaza Mv
- Pollock C
- Pollock Carol
- Popa Ar
- Popenda G
- Popovic-Radinovic V
- Portoles Perez Jm
- Prasad N
- Proietto J
- Prozesky H
- Pumprla J
- Purighalla R
- Quesada Sim\uf3n Ma
- Quesada-Suarez L
- Rabasa-Lhoret R
- Raduan Ra
- Raffaele P
- Railey M
- Ramirez Roca La
- Ramos Jc
- Ramtoola S
- Ranetti Ae
- Rangelov R
- Ranjan R
- Raskina T
- Rastogi S
- Ratnasingam V
- Reddy J
- Reddy J
- Ren Y
- Rendell M
- Resk Jh
- Revesz K
- Rewerska B
- Reyes Rosano Ma
- Rheeder P
- Rich L
- Rista L
- Roberts A
- Robinson M
- Rodriguez Papini N
- Rodriguez Pattzi H
- Rodriguez H
- Roger S
- Rosas Guzman J
- Rosas S
- Rose L
- Rosero R
- Rosivall L
- Roussel R
- Rucker Joerg Ie
- Rychl\uedk I
- Rychlik I
- S\ue1nchez Arenales Ja
- Saaveddra Sanchez Sb
- Saavedra Gajardo V
- Saba F
- Sakakibara T
- Sala J
- Salazar Ma
- Samoylov O
- Samoylova Y
- Sanchez Mijangos Jh
- Sanchez Polo Jv
- Sankaram R
- Santoro D
- Santos F
- Santos Jc
- Saporito W
- Sarin R
- Sasso Fc
- Satyanarayana Rk
- Saudek F
- Saulnier Pj
- Saxena M
- Sazonova O
- Scharfstein D
- Schiavi Lb
- Schiller A
- Schmidt M
- Schreiman R
- Schuch T
- Scott D
- Scott R
- Scotton As
- Seeber M
- Sekkarie M
- Sennik D
- Sensenbrenner J
- Serafinceanu C
- Serrano Sanson P
- Serviddio G
- Sessa H
- Shahinfar S
- Shakeel M
- Shamkhalova M
- Shanik M
- Shaw S
- Sheth S
- Sheu Wh
- Shinkov A
- Shutemova E
- Shwartz Y
- Sim\uf5es de Almeida R
- Simo Canonge R
- Simon G
- Singh B
- Sinha Ad
- Slompo Ramos C
- Smatanova I
- Smirnov I
- Smith Casabella T
- Smith S
- Soares Fel\uedcio J
- Solomon R
- Song W
- Sood V
- Soto Gonzalez A
- Soto Mb
- Sowinski D
- Sprague A
- Spry L
- Sreedhar R
- Sreelatha M
- Starzec A
- Steele A
- Stella A
- Stephens J
- Strzelecka A
- Suchinda P
- Sudhakar B
- Sultan S
- Sun J
- Sun L
- Surampudi P
- Sussman S
- Svyshchenko Y
- Symonds R
- Takacs R
- Takai M
- Tamayo Y Orozco JA
- Tan A
- Tan G
- Tangri N
- Tellez Chavez E
- Temelkova M
- Terns Riera M
- Terrelonge A
- Terront Lozano Ma
- Tesar V
- Thervet E
- Thimmaiah R
- Thom\ue9 F
- Thompson M
- Tibes Hachmann Jc
- Tinahones Madueno Fj
- Toarba C
- Tolentino M
- Tomashkevych H
- Tomonaga O
- Topchii I
- Torshizi A
- Travis K
- Trespalacios F
- Trevisan R
- Trippe B
- Trueba P
- Tryshchuk N
- Tsang V
- Tseluyko V
- Tsujimoto M
- Tu P
- Turchin A
- Turcios Juarez E
- Turner W
- Twahirwa M
- Ulla Mr
- Updegrove J
- Urbanaviciene E
- Uriasyev O
- Valderrama Cometa L
- Valdes Depeda A
- Valdez M
- Valenzuela A
- Valis M
- Vallejos A
- Van Buren P
- Vangel S
- Vannorsdall M
- Vargas Alonso Rd
- Varghese F
- Vasas S
- Vazelov E
- Vejar M
- Velasquez-Mieyer P
- Velichkova E
- Venegas Carrillo L
- Vengadasalam P
- Ventrapragada S
- Veronelli Am
- Villagordoa Mesa J
- Villarino A
- Villegas I
- Visco Ve
- Vizir V
- Vlasenko M
- von Ingersleben G
- Vorobyev S
- Vukotic G
- Vyasam Rc
- Wada T
- Wadud K
- Wahba M
- Wakasugi M
- Wakeling J
- Wakida Y
- Walker R
- Wang G
- Wang H
- Warren M
- Wassermann A
- Watanabe T
- Watson E
- Watson H
- Watts R
- Weiner D
- Weiner P
- Welker J
- Welsh J
- Wheeler D
- Wheeler David C
- Wheeler Dc
- Williams M
- Williams S
- Winocour P
- Wong Ac
- Woo V
- Yakov A
- Yamada M
- Yamada S
- Yanagida K
- Yanase T
- Yang J
- Yao C
- Yap Ye
- Yavin Yshai
- Ygpuara Mdl
- Yin A
- Yoiti Hayashida C
- Yoon Kh
- Yost L
- Young S
- Yu X
- Yumita W
- Yupanqui H
- Zaidman Cj
- Zalunardo N
- Zamarripa Escobedo R
- Zanata Petry Tb
- Zanella Mt
- Zaniewski-Singh M.
- Zanoli L
- Zaoui P
- Zateyshchikova A
- Zateyshshikov D
- Zaviriukha V
- Zemek S
- Zhang H
- Zhang Hong
- Zhao M
- Zheng H
- Zinman B
- Zinman Bernard
- Zlova T
- Zsom M
- Zub L
- Zykova T
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to 300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m 2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
- Author
- A Kaldun Nossuli
- Aamir Jamal
- Adalbert Schiller
- Adam Cheifetz
- Adarsh Daswani
- Adeera Levin
- Adline Ghazi
- Adrian Guinsburg
- Adriana Cif
- Adriana Gabriela Onaca
- Adriana Ilavska
- Adriana Villarino
- Agarwal R.
- Agnieszka Starzec
- Ahmed Arif
- Ahmed Awad
- Aiping Yin
- Akimichi Asano
- Alan Jackson
- Alan McMahon
- Alan Perlman
- Alberto Di Carlo
- Alberto Esquenazi
- Alejandra Oviedo
- Alejandro Valdes Depeda
- Aleksandra Kendereski
- Alex Valenzuela
- Alexander Dreval
- Alexander Gonzalez
- Alexander Shinkov
- Alexander Turchin
- Alexandre Klein
- Alfonso Soto Gonzalez
- Alfred Penfornis
- Alfredo Chew Wong
- Alfredo Wassermann
- Ali Torshizi
- Alicia Chilito
- Alina Agafyina
- Alison Dawson
- Alva Hansraj
- Amer Al-Karadsheh
- Amorin Remus Popa
- Amrendra Kumar
- Amy Sprague
- Ana Limos
- Ana Maria Cusumano
- Ana Maria Elosegui
- Anabella Amigo
- Anatoliy Kazmirchuk
- Andrea Phillips
- Andrea Stella
- Andreas Maddux
- Andrej Dzupina
- Andres Alvarisqueta
- Andrew Johnson
- Andrew O'Shaughnessy
- Andrew Steele
- Andrian Yakov
- Andrzej Januszewicz
- Andrzej Madej
- Angelina Angelova
- Anibal Gastaldi
- Anil Gupta
- Anita Bhajan Manocha
- Anjanette Tan
- Anna Kaminska
- Anna Maria Veronelli
- Anna Strzelecka
- Anna Zateyshchikova
- Anselmo Bordonava
- Antanas Navickas
- Anthony Gunstone
- Anthony Roberts
- Antonio Ceriello
- Antonio Galan Serrano
- Antonio Scafuto Scotton
- Antonio Terrelonge
- Antônio Roberto Chacra
- Anupama Gowda
- Arjun D Sinha
- Armando Perez
- Ashot Mkrtumyan
- Atanas Koundurdjiev
- Augusto Vallejos
- Aurelian-Emil Ranetti
- Ayim Akyea-Djamson
- Aysha Badat
- Bakris G.
- Baldev Singh
- Barbara Greco
- Barbara Kaczmarek
- Barbara Rewerska
- Barry M Brenner
- Belia Martin Del Camp Blanco
- Bernard Zinman
- Bertrand Cariou
- Bertrand Dussol
- Bhasker Mehta
- Bhimavarapu Sudhakar
- Björn Paschen
- Bompoint S.
- Borys Mankovskyy
- Botond Csiky
- Boyan Nonchev
- Brenner B. M.
- Brett Kissela
- Brian Nichol
- Bruce Neal
- Bruce Trippe
- Bruno Geloneze Neto
- Bull S.
- Byung-Wan Lee
- C B Keshavamurthy
- Cannon C. P.
- Capuano G.
- Carlo Giorda
- Carlos Alberto Cuneo
- Carlos Arauz-Pacheco
- Carlos Barrera
- Carlos Perez
- Carmel Hawley
- Carmen Crisan
- Carol Pollock
- Carolyn Droste
- Caroucel Chuateco
- Caryl David
- Cecilia Garcia Ballesteros
- Cecilia Jimeno
- Celso Amodeo
- Cesar Javier Zaidman
- Cesar Yoiti Hayashida
- Chamberlain Obialo
- Chang-Hsun Hsieh
- Charles Cook
- Charles Kaupke
- Charytan D. M.
- Chek Loong Loh
- Chen Leia
- Cheol-Young Park
- Chih-Ching Lin
- Christopher P Cannon
- Christy Yao
- Chu P. -L.
- Chwen-Tzuei Chang
- Chye Lee Gan
- Clara Barrios
- Claude Galphin
- Claudia Goycoa
- Claudia Moreira de Brito
- Clodoaido Caringal
- Cristian Serafinceanu
- Cristina Toarba
- Cristobal Morales Portillo
- Csaba Kovesdy
- Cynthia Bowman-Stroud
- Cynthia Christiano
- Cynthia Mustieles Rocha
- Cyrus Desouza
- Cássio Slompo Ramos
- Dagmar Bartaskova
- Dale Crawford Allison
- Dalia Kozloviene
- Dan Scharfstein
- Dana Cosma
- Daniel Coyne
- Daniel Hiser
- Daniel Kolansky
- Daniel Panarotto
- Daniel Pella
- Daniel Weiner
- Daniil Chizhov
- Dariusz Sowinski
- Darren K McGuire
- Davesh Sennik
- David C Wheeler
- David Cherney 3rd
- David Gorson
- David Johnson
- David M Charytan
- David Packham
- David Scott
- David Wheeler
- De Zeeuw D.
- Debbie Cohen-Stein
- Debbie Mascaro
- Deepak Koppolu
- Dennis Levinson
- Derek Lewis
- Detian Li
- Devasmita Dev
- Devesh Patel
- Dewan Deepak
- Dick de Zeeuw
- Diego Aizenberg
- Dinesh Jain
- Dinesh Khullar
- Diogo Belo
- Dmitry Zateyshshikov
- Domenico Santoro
- Domingos d'Avila
- Donald Brandon
- Donald Fraser
- Dong-Wan Chae
- Dora Inés Molina de Salazar
- Dorota Mlodawska-Choluj
- Doru Negru
- Edgar Arcos
- Edoardo Mannucci
- Eduardo Farias
- Edward Watson
- Edwards R.
- Egle Gaupsiene
- Egle Urbanaviciene
- Ekaterina Velichkova
- Elena Christofides
- Elena Grineva
- Elena Kolmakova
- Elena Shutemova
- Eleonora Harcsa
- Elizabeth Barranco
- Elizabeth Gelersztein
- Elizabeth Kern
- Elizete Keitel
- Eloisa Tellez Chavez
- Emanuela Orsi
- Emil Martinka
- Emyr Davies
- Enrique Gonzalez
- Eric Alamartine
- Eric Hernandez Triana
- Eric Thervet
- Erick Turcios Juarez
- Esteban Cercos
- Eugenia Galindo-Ramos
- Eva Peterfai
- Evaly Chen
- Evandro de Souza Portes
- Evgueniy Vazelov
- Fabian Otreras
- Fabiana Loss de Carvalho Contieri
- Fabio Malberti
- Fadi Saba
- Fadlo Fraige Filho
- Favio Edmundo Enriquez Sosa
- Fayzal Ahmed
- Ferdinando Carlo Sasso
- Fernanco Augusto Alves da Costa
- Fernanda Cristina Camelo Sanches
- Fernando Cereto Castro
- Fernando Flores Lozano
- Fernando Jimenez Florez
- Fernando Krynski
- Fernando M Edwin
- Fernando Thomé
- Fernando Trespalacios
- Florence Santos
- Florencia Kraft
- Fracisco Javier Gonzalez Martinez
- Fran Morren
- Franciso Jose Tinahones Madueno
- Frank Eder
- Franklin Joseph
- Franklin Paul Haase
- Frantisek Saudek
- François Dubé
- François Madore
- Freemu Varghese
- Gabriela Cecilia Coloma
- Gabriela Genova-Hristova
- Gabriele von Ingersleben
- Gaetano Serviddio
- Galina Nagibovich
- Gary Meininger
- Gema Fernandez Fresnedo
- Georg Plassmann
- George Bakris
- George Hon
- George Newman
- Gerald DaRoza
- Gerald Keightley
- Gerry Tan
- Giacomo Garibotto
- Giorgio Fuiano
- Giovanni Frascà
- Giovanni Gambaro
- Giuseppe Derosa
- Gizella Petro
- Glenn Chertow
- Gnyandev Patel
- Godwin Simon
- Goga Vukotic
- Gopal Krishna
- Grace Aquitania
- Grace Lin
- Graham Hillis
- Graziano Di Cianni
- Grazyna Orlowska-Kowalik
- Grazyna Popenda
- Greene T.
- Greg Fulcher
- Gregorio Obrador
- Gregorio Obrador Vera
- Grit Faulmann
- Guadalupe Morales Franco
- Guillermo Fragale
- Guixia Wang
- Gulam Latiff
- Gustavo Cristian Greloni
- Guy Chouinard
- Gyongyi Csecsei
- Gyorgy Paragh
- Halyna Tomashkevych
- Hans Prozesky
- Harpreet Bajaj
- Hasnain Khandwala
- Hector Rodriguez
- Heerspink H. J. L.
- Helena Oosthuizen
- Hendrik Nortje
- Henry Watson
- Hermann Haller
- Hernan Finkelstein
- Hernan Yupanqui
- Hiddo J L Heerspink
- Hiralal Maheshwari
- Hiroko Oishi
- Hiromi Aoki
- Hiromi Rodriguez Pattzi
- Hiroshi Kono
- Hitoshi Akiyama
- Holly Wang
- Hong Mao
- Hong Zhang
- Hongguang Zheng
- Hongli Lin
- Horacio Sessa
- Hugo Colombo
- Hugo Laviada Molina
- Hugo Roberto Kurtz Lisboa
- Humberto Pavon
- Hyuk-Sang Kwon
- Iain MacDougall
- Ian Fraser
- Idalia Acosta
- Ildiko Halmagyi
- In-Kyung Jeong
- Ines Bartolacci
- Ingrid Abrahamsen
- Ingrid Buganova
- Inna Kolesnyk
- Ioana Emilia Ferariu
- Irene Noronha
- Irina Glinkina
- Irina Osipova
- Iryna Dudar
- Isabel Erika Rucker Joerg
- Isabel Garcia
- Isam Marar
- Israel Hartman
- Iuliia Komisarenko
- Ivan Fushtey
- Ivan Ory
- Ivan Rychlik
- Ivan Rychlík
- Ivan Smirnov
- Ivan Topchii
- Ivan Villegas
- Iveta Smatanova
- Jaco Jurgens
- Jakkidi Reddy
- Jamal Hammoud
- James Conway
- James Januzzi
- James Welker
- Jan Culak
- Jana Babikova
- Jana Belobradkova
- Jana Dzuponova
- Janos Mucsi
- Jardine M. J.
- Jason Gaglia
- Javier Narvarte
- Javier Nieto Iglesias
- Jayameena Peringat
- Jayant Kumar
- Jean Carlo Tibes Hachmann
- Jean Welsh
- Jean-Pierre Fauvel
- Jeevren Reddy
- Jeffrey Kropp
- Jeffrey Stephens
- Jeimeen Agra
- Jelena Ignjatovic
- Jesus Cuadrado
- Jesus Egido de Los Rios
- Jian Liu
- Jiao Sun
- Jinkui Yang
- Jiri Lastuvka
- Jiri Pumprla
- Joaquin Pablo Gonzalez
- Johannes Breedt
- John Amerena
- John Baker
- John Ervin
- John Evans
- John Lentz
- John Middleton
- John Padron
- John Sensenbrenner
- John Updegrove
- John Wakeling
- Jonay Pantoja Perez
- Jorge Archibaldo Glenny
- Jorge Avendano
- Jorge Ernesto Andres Diaz Ruiz
- Jorge Hector Resk
- Jorge Kusnir
- Jorge Mordujovich
- Jorgelina Sala
- Jose Antonio Sánchez Arenales
- Jose Chevaile Ramos
- Jose David Gomez Rangel
- Jose Esteban Jodar Gimeno
- Jose Francisco Kerr Saraiva
- Jose Hector Sanchez Mijangos
- Jose L Górriz
- Jose Luis Accini Mendoza
- Jose Ma Portoles Perez
- Jose Osvaldo Fretes
- Jose Ricardo Correa Rotter
- Joseph Abdallah
- Joseph Aiello
- Joseph Feuerstein
- Joseph O'Hare
- Joseph Proietto
- Josier Nisnisan
- José Vicente Sanchez Polo
- João Lindolfo Cunha Borges
- João Soares Felício
- Juan Alfredo Tamayo Y Orozco
- Juan Baas Cruz
- Juan Carlos Santos
- Juan Diego Higuera
- Juan Frias
- Juan Gonzalo Godoy Jorquera
- Juan Pablo Albisu
- Juan Pablo Moreira Diaz
- Juan Peralta Calcaneo
- Juan Rosas Guzman
- Juan Villagordoa Mesa
- JungEun Lee
- Kamal Abouglila
- Karel Peterka
- Karina Hufert
- Karlton Pettis
- Katalin Keltai
- Katalin Revesz
- Katarina Halciakova
- Katarina Lalic
- Kathy Nicholls
- Kati De Brouwer
- Kazuhiro Yanagida
- Kazunori Koyama
- Kazuyuki Mizuyama
- Kee Sing Ng
- Kenneth Cohen
- Kenneth Deck
- Kenneth Hershon
- Kenneth Liss
- Kenneth W Mahaffey
- Khalid Abdul Kadir
- Khurram Wadud
- Kim Travis
- Kiril Hristozov
- Kook-Hwan Oh
- Krisztian Kiss
- Kun Ho Yoon
- Lachezar Lozanov
- Lajos Major
- Lalaine Delos Santos
- Landman Lombard
- Larisha Pillay-Ramaya
- Larry Distiller
- Larysa Pererva
- Laszlo Deak
- Laszlo Konyves
- Laura Akright
- Laura Coffee
- Lawrence Distiller
- Lawrence Lehrner
- Lawrence Leiter
- Lech Lazuka
- Lee-Ming Chuang
- Lenka Dohnalova
- Leslie Spry
- Levin A.
- Li Yuan Lee
- Lidia Bermudez
- Ligia Petrica
- Lilia Beatriz Schiavi
- Liliana Monica Angelescu
- Liliia Zub
- Liliya Martynyuk
- Lin Sun
- Lincoln Chapin
- Linong Ji
- Lisa Rich
- Liudmila Kvitkova
- Lori Yost
- Luca Chiovato
- Luca De Nicola
- Luca Zanoli
- Lucas Rista
- Luciane Mônica Deboni
- Lucyna Hotlos
- Ludger Rose
- Luigi Gnudi
- Luis Alberto Ramirez Roca
- Luis Asmarats Mercadal
- Luis David Abraira Munoz
- Luis Enrique Herrera Jimenez
- Luis Fernando Flota Cervera
- Luis Henrique Canani
- Luis Hernando Garcia Ortiz
- Luis Isaias Juncos
- Luis Quesada-Suarez
- Luis Rodolfo Cartasegna
- Luis Valderrama Cometa
- Luis Venegas Carrillo
- Luiz Alberto Andreotti Turatti
- Luiza Despina Demian
- László Rosivall
- Ma Dovie Lallaine Ygpuara
- Mahaffey K. W.
- Manel Terns Riera
- Manish Saxena
- Manthi Hettiarachchi
- Manuel Muñoz Lopez Mendoza
- Manuel Muñoz Torres
- Manuela Schmidt
- Marc Rendell
- Marcel Twahirwa
- Marcelo Medina Fariña
- Marcora Mandreoli
- Marcus Gomes
- Margarita Temelkova
- Margarita Vejar
- Margit Mileder
- Margo Hudson
- Maria Antonia Munar Vila
- Maria Barnard
- Maria Cecilia Cantero
- Maria Florencia Fernandez
- Maria Isabel Klyver
- Maria Jaime
- Maria Rosa Ulla
- Maria Teresa Zanella
- Maria Valdez
- Marializa Bernardo
- Marianna Zsom
- Mario Alberto Berli
- Mario Burgos Soto
- Mark Davies
- Mark Vannorsdall
- Mark Warren
- Markus Faghih
- Marsha Tolentino
- Marta Dominquez Lopez
- Marta Molnar
- Martin Lukac
- Martin Valis
- Martine Destree
- Mary Anne Lim-Abrahan
- Mary Lawrence
- Mary Seeber
- Maryna Vlasenko
- María Alicia Fernández Montenegro
- María Angustias Quesada Simón
- Masahiko Takai
- Masahiro Koizumi
- Masakiyo Wakasugi
- Masayo Yamada
- Mastura Ismail
- Matthew Abramowitz
- Matthew Beacom
- Meg J Jardine
- Meg Jardine
- Meininger G.
- Melchor Alpizar Salazar
- Melemadathil Sreelatha
- Merce Perez Vera
- Mercedes Velo Plaza
- Michael Oliver
- Michael Robinson
- Michael Shanik
- Michael Thompson
- Michael Williams
- Michal Nowicki
- Michał Nowicki
- Michelle Zaniewski-Singh
- Mick Kumwenda
- Miguel Nazzer Hissa
- Migues Angel Reyes Rosano
- Mihaela Biscoveanu
- Mihaela-Magdalena Busegeanu
- Mihaly Dudas
- Milan Gupta
- Min Jeong Kwon
- Minara Shamkhalova
- Minghui Zhao
- Miodrag Djordjevic
- Mircea Munteanu
- Mitsuru Tsujimoto
- Mohamed El-Shahawy
- Mohamed Mookadam
- Mohamed Railey
- Mohamed Sekkarie
- Mohanram Narayanan
- Mohd Daud Che Yusof
- Mohsen El Kossi
- Mona Wahba
- Monica Alexandra Terront Lozano
- Monika Dhillon
- Moogali Arvind
- Moon-Kyu Lee
- Moon-Suk Nam
- Moustafa Moustafa
- Muhammad Shakeel
- Mukesh Joshi
- Mykola Kolesnyk
- Márcio Antônio Pereira
- Nadia Zalunardo
- Nadiya Tryshchuk
- Nan Chen
- Narayan Prasad
- Naresh Aggarwal
- Natalia Malaver
- Nataliia Pashkovska
- Natarajan Gopalakrishnan
- Navdeep Tangri
- Naveen Atray
- Neal B.
- Nebojsa Lalic
- Neil Kumar
- Nelson Kopyt
- Nelson Rodriguez Papini
- Nestor Horacio Garcia
- Ngai Wah Cheung
- Nicolae Hancu
- Nicole Li
- Nik Nur Fatnoon Nik Ahmad
- Nina Patel
- Nizar Daboul
- Noble Gracious
- Nomangesi Ngcakani
- Nonna Kravchun
- Nora Marchetta
- Norman Muirhead
- Norsiah Ali
- Oleg Legun
- Oleg Nagibovich
- Oleg Uriasyev
- Oleksandr Golovchenko
- Oleksandr Samoylov
- Oleksii Korzh
- Olga Barbarash
- Olga Barna
- Olga Barysheva
- Olga Benusova
- Olga Godlevska
- Olga Gyrina
- Olga Sazonova
- Olivert Gomez
- Oomman Abraham
- Osamu Tomonaga
- Oscar Tarsicio Moreno Loza
- Osvaldo Brusco
- Pablo Antonio Novoa
- Pablo Mele
- Pablo Raffaele
- Pablo Serrano Sanson
- Paranthaman Vengadasalam
- Patricia Del Carmen Gonzalez Colaso
- Patrick English
- Patrick Parfrey
- Paul Ainsworth
- Paul Frenk Baron
- Paul Nixon
- Paul Noonan
- Paul Rheeder
- Paulina Virginia Lanchiotti
- Pavel Weiner
- Peak Mann Mah
- Pedro Calella
- Pedro de Souza
- Pedro Velasquez-Mieyer
- Peggy Barnhill
- Peggy Lin
- Pere Alvarez Garcia
- Perkovic V.
- Peter Danos
- Peter Fulop
- Peter Van Buren
- Peter Winocour
- Petr Barton
- Philip Gorelick
- Philip Home
- Philip Nicol
- Philippe Zaoui
- Phyllis August
- Piermarco Piatti
- Pierre Gourdy
- Pierre-Jean Saulnier
- Pietro Castellino
- Pilar Trueba
- Ping Tu
- Pollock C.
- Prasanth Surampudi
- Pusadee Suchinda
- Qinkai Chen
- Rachel Bregman
- Radica Alicic
- Radu Jacob
- Rafael Simo Canonge
- Raied Abdullah
- Rajendran Alappan
- Rajiv Agarwal
- Rajiv Ranjan
- Raju Sree Bhushan
- Rakesh Gulati
- Rakhi Khanna
- Rallabhandi Sankaram
- Raman Purighalla
- Ramesh Chandra Vyasam
- Ramesh Thimmaiah
- Ramon Berenguer
- Ramon Moreda
- Rangel Rangelov
- Rao K Satyanarayana
- Ravendran Govender
- Ravi Sarin
- Reddy Sreedhar
- Reginald Parker
- Rehan Symonds
- Reinhold Jerwan-Keim
- Remi Rabasa-Lhoret
- Renan Montenegro Junior
- Renata Bijata-Bronisz
- Rhea Severina Comia
- Rhonda Bentley-Lewis
- Riad Darwish
- Ricardo Alfonso Leon de la Fuente
- Ricardo Dario Dran
- Ricardo Rosero
- Riccardo Bonadonna
- Richard Ferkl
- Richard Kovar
- Richard Lindley
- Richard Orozco Castellanos
- Richard Solomon
- Robert Busch
- Robert Cohen
- Robert Schreiman
- Robert Takacs
- Robert Walker
- Roberto Abrão Raduan
- Roberto Jorge da Silva Franco
- Roberto Pecoits Filho
- Roberto Pecoits-Filho
- Roberto Simões de Almeida
- Roberto Trevisan
- Rodica-Ioana Avram
- Rodolfo Andres Ahuad Guerrero
- Rohana Abdul Ghani
- Rohit Pankhaniya
- Rolando Zamarripa Escobedo
- Ronald Goldenberg
- Ronald Harris
- Ronald Watts
- Ronaldo Arturo Gonzalez Orellana
- Ronan Roussel
- Ronnie Aronson
- Rosa Isela Luna Ceballos
- Rosângela Milagres
- Ruben Dario Vargas Alonso
- Rury Holman
- Russell Scott
- Sacha De Serres
- Sahay Manisha
- Saiful Shahrizal Bin Shudim
- Sailaja Ventrapragada
- Salah Abusnana
- Salvatore De Cosmo
- Sam Henein
- Sam Philip
- Samuel Cohen
- Samuel Mujica Trenche
- Samy Hadjadj
- Sandor Keresztesi
- Sandor Vangel
- Sandra Berenice Saaveddra Sanchez
- Sanjeev Rastogi
- Sara Jaffer
- Sarah Olelewe
- Satoshi Ota
- Satu Pesickova
- Scott Kasner
- Secundino Cigarran Guldris
- Senan Sultan
- Serge Cournoyer
- Sergei Nedogoda
- Sergey Vorobyev
- Sergio Saul Irizar Santana
- Shahabul Arfeen
- Shahnaz Shahinfar
- Shang-Jyh Hwang
- Shelley Williams
- Shenaz Ramtoola
- Shenglian Gan
- Sherry Sussman
- Shizuo Kajiyama
- Shozo Miyauchi
- Silvia Ines Orio
- Silvia Nicolai
- Simon Davies
- Simon Roger
- Simon Young
- Sin Gon Kim
- Singhan Krishnan
- Sini George
- Slobodan Antic
- Sohan Dua
- Sonia Hermida
- Soo Kun Lim
- Sophie Borot
- Souhila Ounadjela
- Sreedhar Mandayam
- Srikanth Bellary
- Stanislav Zemek
- Stanislaw Mazur
- Stefan Dimitrov
- Stephan Maxeiner
- Stephen Grubb
- Stephen Smith
- Steven Fishbane
- Stuart Handelsman
- Suely Keiko Kohara
- Sun Kim
- Sun-Hee Park
- Sunil Sheth
- Susumu Kashine
- Svetlana Goykhman
- Svitlana D Bilyk
- Swee Win Lam
- Sylvia Rosas
- Sylvia Shaw
- Szilard Vasas
- Sérgio Alberto Cunha Vêncio
- Sérgio Yamada
- Tadashi Iitsuka
- Takamoto Kodera
- Takashi Wada
- Takayuki Watanabe
- Tamara Malek Marin
- Tamas Oroszlan
- Tara Chang
- Tareq Nassar
- Tarissa Beatrice Zanata Petry
- Tatiana Koroleva
- Tatiana Morugova
- Tatiana Raskina
- Tatyana Zykova
- Te-Lin Hsia
- Terue Sakakibara
- Tetiana Zlova
- Tetsuji Niiya
- Tetyana Pertseva
- Tiago Schuch
- Timothy Hall
- Tom Christensen
- Tom Greene
- Tomas Drasnar
- Tomas Smith Casabella
- Tonatiu Diaz Escalante
- Toshihiko Yanase
- Toshio Kawada
- Vadym Vizir
- Vanassa Ratnasingam
- Venessa Tsang
- Venkata Behara
- Vera Klokocnikova
- Vera Krane
- Veronica Anghel
- Veselka Genadieva
- Vesna Popovic-Radinovic
- Viacheslav Marasaev
- Victor Commendatore
- Victor Saavedra Gajardo
- Vijayaraman Arutchelvam
- Viktor Margaritov
- Viktor Zaviriukha
- Viktoria Andreeva
- Vimladhevi Govender
- Vincent Pichette
- Vincent Woo
- Vira Tseluyko
- Virginia Esther Visco
- Vivek Sood
- Vivekan Jha
- Vladimir Dobronravov
- Vladimir Khirmanov
- Vladimir Tesar
- Vlado Perkovic
- Volker Burst
- Volodymyr Botsyurko
- Walter Guillermo Douthat
- Walter Pharr
- Wasim Hanif
- Wataru Yumita
- Wayne H-H Sheu
- Wayne Turner
- Wei Yen Kong
- Weihong Song
- Weiping Lu
- Wendy Lane
- Wenge Li
- Wheeler D. C.
- Wladmir Saporito
- Xuemei Li
- Xueqing Yu
- Yamil Canaan
- Yan Ren
- Yannick Le Meur
- Yaozhong Kong
- Yasuro Kumeda
- Yasushi Wakida
- Yavin Y.
- Yeong Hoon Kim
- Yevgeniya Svyshchenko
- Young Min Cho
- Yulia Samoylova
- Yung-Chuan Lu
- Yuriy Mostovoy
- Yuriy Shwartz
- Yvette Ethel Yap
- Zaynab Abejuela
- Zdravko Kamenov
- Zeid Khitan
- Zhang H.
- Zinman B.
- Zishan Ali
- Zuzana Ochodnicka
- Ângela Regina Nazario Sabbag
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Quadrupole interaction of Co59 in cobaltic complexes
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Nitrogen quadrupole resonance spectroscopy
- Author
- A. Colligiani
- A. Narath
- A. Tzalmona
- A. Zussman
- A. Zussman
- A. Zussman
- A. Zussman
- C. H. Townes
- C. H. Townes
- C. P. Smyth
- C.T. O'Konski
- D. H. Smith
- E. A. C. Lucken
- E. Schempp
- E. Schempp
- E. Schempp
- E. Schempp
- E. Schempp
- E. Schempp
- E.A.C. Lucken
- E.A.C. Lucken
- F. A. Cotton
- F. N. H. Robinson
- G. A. Matzkanin
- G. A. Matzkanin
- G. Brieglieb
- G. W. Leppelmeier
- G. W. Smith
- H. Bayer
- H. Betsuyaku
- H. Negita
- H. Negita
- H. S. Gutowsky
- J. L. Colot
- J. P. Lucas
- J. Sheridan
- L. Guibé
- L. Guibé
- L. Guibé
- L. Guibé
- L. Guibé
- L. Guibé
- L. O. Andersson
- M. Gourdji
- M. Minematsu
- M. Read
- P. A. Casabella
- P. J. Haigh
- P. J. Haigh
- P.A. Casabella
- R. A. Marino
- R. A. Marino
- R. A. Marino
- R. A. Marino
- R. Clément
- R. H. Widman
- R. Ikeda
- R. Ikeda
- R. Ikeda
- R. Ikeda
- R. Ikeda
- R. J. Kurland
- S. Alexander
- S. Eletr
- S. Eletr
- S. Lehrer
- S. Onda
- T. Kushida
- T. Kushida
- T. Oja
- T. Oja
- T.P. Das
- W. T. P. Choy
- W. Werner
- Y. Abe
- Y. Abe
- Y. Kato
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1972
- Field of study
Cardiovascular and renal outcomes with empagliflozin in heart failure
- Author
- A Adlakha
- A Akhtar
- A Alvarisqueta
- A Bakhai
- A Banerjee
- A Bazzoni Ruiz
- A Begemann
- A Begg
- A Bhagwat
- A Birkenfeld
- A Caccavo
- A Cohen
- A Costa-Vitali
- A Djamson
- A Facta
- A Fernandez
- A Friart
- A Fucili
- A Ghanem
- A Gupta
- A Hamilton
- A Janik
- A Jobbe Duval
- A Kalinka
- A Karim
- A Leone
- A Linhart
- A Madej
- A Malik
- A Matoltsy
- A Mehta
- A Mullasari
- A Nagy
- A Nakata
- A Ogimoto
- A Onwuanyi
- A Oomman
- A P van Alem
- A Pandey
- A Paraschos
- A Potler
- A Salacata
- A Salvioni
- A Sauer
- A Shen
- A Sverdlov
- A Takaishi
- A Ujeyl
- A Vest
- A Vorobcsuk
- A Wada
- A Wilke
- A Yilmaz
- A Z Maria Middelares
- A Zhai
- A Zurakowski
- Anker S. D.
- B Ellis
- B Firek
- B Harris
- B Iteld
- B J W M Rensing
- B Kietselaer
- B Krakowiak
- B Lemke
- B Lubelsky
- B McLaurin
- B Merkely
- B Rama
- B Shah
- B Trichon
- B Tyrrell
- B Winkelmann
- B Wozakowska-Kaplon
- B Yoo
- Bocchi E.
- Bohm M.
- Brueckmann M.
- Brunner-La Rocca H. -P.
- Butler J.
- C A de Freitas Zerbini
- C Alvarez Lorio
- C Arden
- C Broome-Webster
- C Calvo Vargas
- C Clifford
- C Constance
- C East
- C Hernandez Herrera
- C Majul
- C Mazzone
- C P Schulze
- C Poy
- C R Sampaio
- C Sai-Sudhakar
- C Stellbrink
- C Travill
- C Vieira Nascimento
- C Zaidman
- Carson P.
- Choi D. -J.
- Chopra V.
- Chuquiure E.
- Cotton D.
- D Anauch
- D Babuty
- D Cheung
- D Choi
- D Colquhoun
- D Dion
- D Foldyna
- D Kahali
- D Kim
- D Lombardo
- D Mikhalkova
- D Pascual Figal
- D Peng
- D Perez de Arenaza
- D Piskorz
- D Precoma
- D Price
- D Prior
- D Savard
- D Tomasevic
- D Yung
- E A Bocchi
- E Bonnefoy Cudraz
- E Bush
- E Chuquiure Valenzuela
- E De Vuyst
- E Hasbani
- E Kemala
- E Lonn
- E McMillan
- E Mirek-Bryniarska
- E Noori
- E Perna
- E R Manenti
- E Swiggum
- E Szolnoki
- E Vasconcellos
- EMPEROR-Reduced Trial Investigators: D Aizenberg
- F A Alves da Costa
- F C Neuenschwander
- F Cereto Castro
- F Chenot
- F Colombo Berra
- F Cosmi
- F Fedele
- F G Padilla Padilla
- F J Neves Mancuso
- F L Gomes
- F Lakatos
- F McGrew
- F Picard
- F R den Hartog
- F Roubille
- F Santos
- F Villaça Guimarães Filho
- Filippatos G.
- G C M Linssen
- G Carnero
- G Curnew
- G Drelich
- G Esposito
- G Gonçalves
- G Habib
- G Hiasa
- G Jenkins
- G Kania
- G Kim
- G Kline
- G Llamas Esperon
- G Miller
- G Raczak
- G Reis
- G Simon
- G Skoczylas
- G Skonieczny
- G Stevens
- G Vaddadi
- G Vervoort
- G Yang
- Giannetti N.
- Gonzalez Juanatey J. R.
- H Bourhaial
- H Brunner-La Rocca
- H Bui
- H Burianova
- H C Finimundi
- H Cho
- H Colombo
- H Darius
- H Düngen
- H Ebert
- H Fujinaga
- H Hori
- H Ince
- H Luquez
- H Olbrich
- H Saint-Jacques
- H Sarnighausen
- H Sekino
- H Serota
- H Sessa
- H Skopicki
- H Sugiyama
- H Takaishi
- H Tsuboi
- H Uehara
- H Urata
- H Vandekerckhove
- H Yamamoto
- I C D Westendorp
- I Dauber
- I Labin
- I Lopez Alcocer
- I Rodriguez Briones
- I Squire
- I Szakal
- J A Kragten
- J A Ribas Fortes
- J Alexandre
- J Almeida Alvarado
- J Amerena
- J Ascenção de Souza
- J Bauersachs
- J Berlingieri
- J Berneau
- J Bono
- J Carrillo Calvillo
- J Cervantes Escárcega
- J Choi
- J Coller
- J Contreras
- J Cox
- J Da Silveira
- J De Sutter
- J Delgado Jiménez
- J Dubois-Rande
- J Dy
- J F Kerr Saraiva
- J Fialkow
- J Forys
- J Glenny
- J González Juanatey
- J Grzybowski
- J Gómez
- J Hubac
- J Illescas Díaz
- J Jeong
- J Jurowiecki
- J Kim
- J Kobayashi
- J Krupicka
- J Lavoie
- J Lin
- J López-Sendón
- J Ma
- J Needell
- J Neutel
- J Oh Na
- J Peruga
- J Post
- J Resk
- J Ricci
- J Sauter
- J Schmedtje
- J Shankar
- J Shin
- J Spiegelman
- J Spyra
- J Szachniewicz
- J Tallaj
- J Vaclavik
- J Vesely
- J Welker
- J Wong
- J Yan
- J Ye
- J Yu
- J Zhang
- Jamal W.
- Janssens S.
- Januzzi J.
- K Adams
- K Anderson
- K Anderson
- K Barringhaus
- K Carr
- K Challappa
- K Cymerman
- K Ferdinand
- K Friedman
- K Fukui
- K Hirabayashi
- K Kawamitsu
- K Kobayashi
- K Kostner
- K Maeno
- K Munuswamy
- K Nakayama
- K Oku
- K Okuhara
- K Otomo
- K Radwan
- K Stania
- K Vora
- K Yonezawa
- K Yousuf
- K Zeman
- Kaul S.
- Kimura K.
- L A Saliba
- L Beck da Silva Neto
- L Bellersen
- L Busak
- L Cartasegna
- L Danilowicz-Szymanowicz
- L de la Fuente Galán
- L Guzman
- L H Canani
- L Handoko
- L Hill
- L Koenyves
- L Lobo Márquez
- L M Backes
- L Maia
- L Maier
- L Noronha
- L Paladino
- L Pliamm
- L Straatman
- L Valle Molina
- L van Heerebeek
- L Yao
- M Aguilera Real
- M Alpizar Salaza
- M Amuchástegui
- M Arikawa
- M Babapulle
- M Barettella
- M Berli
- M Budoff
- M Böhm
- M Cho
- M da Consolação Vieira Moreira
- M Debinski
- M Doi
- M Dupont
- M Faghih
- M Fernandez Moutin
- M Galinier
- M Ginel
- M Grover-McKay
- M Hartleib
- M Heffernan
- M Hernandes
- M Hominal
- M Hong
- M Hyun Kim
- M Ichikawa
- M Imamaki
- M Inoko
- M Kasprzak
- M Kinoshita
- M Koda
- M Koren
- M Krol
- M Kujawiak
- M Leblanc
- M Leithe
- M Licka
- M M Noya Rabelo
- M Manita
- M Mansilla
- M Mori
- M Mumma
- M Najenson
- M Nallasivan
- M Nanasato
- M Nanna
- M Napoli
- M Oguri
- M Prull
- M Pérez de Juan Romero
- M Radvan
- M Rodrigues Bacci
- M Sanmartín Fernández
- M Saxena
- M Scherillo
- M Senni
- M Seronde
- M Shimizu
- M Sicer
- M Suwa
- M Toma
- M V Simões
- M van de Wetering
- M Vidotti
- M Volpe
- M Yagi
- Merkely B.
- N Al-Windy
- N Budassi
- N Delarche
- N Frey
- N Giannetti
- N Girerd
- N Jaffrani
- N Jarmukli
- N Kamalakar Ghaisas
- N Kazemi
- N Laszlo
- N Lewis
- N Manito Lorite
- N Marx
- N Menck
- N Miyagi
- N Proskynitopoulos
- N Tahirkheli
- N Takahashi
- N Uriel
- N Watanabe
- N Watanabe
- N Weintraub
- Nicholls S. J.
- O Jerabek
- O Ludka
- O Pereira Dutra
- O Salomone
- P Andrassy
- P Balfour
- P Balsam
- P Bradley
- P Cervinka
- P Debonnaire
- P Dijkmans
- P Duncan
- P E Leães
- P F M M van Bergen
- P Fajardo
- P Hauptman
- P Hoogslag
- P Khanoyan
- P Kotha
- P McCullough
- P Michalski
- P Miekus
- P Podolec
- P Shah
- P Smits
- P Timmermans
- P Van De Borne
- P Van der Meer
- P Vodnansky
- P Wojewoda
- Packer M.
- Perrone S.
- Pina I.
- Pocock S. J.
- Ponikowski P.
- Q Tang
- R A Leon de la Fuente
- R Abadier
- R Ahuad Guerrero
- R Arora
- R Bhargava
- R Bourgeois
- R Bover Freire
- R Campos
- R Chehayeb
- R Cifkova
- R Dab
- R Ebrahimi
- R Gabor Kiss
- R Gazmuri
- R Goldberg
- R Groutars
- R Isnard
- R Khouzam
- R Koc
- R Littlefield
- R MacNevin
- R Miklik
- R Peters
- R Potu
- R Preto
- R Prosecky
- R Sangrigoli
- R Troquay
- R Tsunoda
- R Van de Wal
- R van Stralen
- R Velasco Sanchez
- R Villarreal
- S Baum
- S Donahoe
- S Dunlap
- S Falkowski
- S Genovese
- S Genth-Zotz
- S Hwan Han
- S Inoue
- S Jani
- S Janssens
- S Kancz
- S Khouri
- S Kindsvater
- S Komarlu
- S Koneru
- S Kouz
- S Li
- S Lu
- S Lupovitch
- S Mahal
- S Matsuoka
- S Matsuoka
- S Mazur
- S Min Kang
- S Nani
- S Oishi
- S Pinney
- S Sakagami
- S Schellong
- S Taddei
- S Taguchi
- S Tsujiyama
- S Verma
- S Virani
- S von Haehling
- S West
- S Woodhouse
- S Yuda
- S Zieroth
- Sattar N.
- Schnee J.
- Senni M.
- Seronde M. -F.
- Spinar J.
- Squire I.
- T Barany
- T Brabec
- T Dorsel
- T Fiala
- T Franco Hirakawa
- T Greene
- T Hashizume
- T Himi
- T Huynh
- T Ide
- T Kadokami
- T Kataoka
- T Koga
- T Koizumi
- T Kubota
- T Matsumoto
- T Matsumura
- T Matsunaga
- T Nadu
- T Nakamura
- T O'Brien
- T Saito
- T Sarens
- T Shinozaki
- T Smith Casabella
- T Sydo
- T Yoshitama
- Taddei S.
- Tsutsui H.
- U Kaul
- V Chopra
- V Durdil
- V Malhotra
- V Marques
- V Mehta
- V Mehta
- V Nguyen
- V Rao
- V Rastogi
- V Vijan
- V Zacà
- V Zaha
- Verma S.
- W de Souza
- W E M Kok
- W Fil
- W Herzog
- W Kus
- W König
- W Musial
- W Nelson
- W Piesiewicz
- W Rieker
- W Zmuda
- Wanner C.
- X Garcia-Moll Marimon
- X Guo
- X Han
- X Jiang
- X Kong
- X Wang
- X Xu
- Y Dong
- Y Fujino
- Y Fukumoto
- Y Furutani
- Y Gonçalves Mello
- Y Kawai
- Y Kazatani
- Y Khaykin
- Y Kijima
- Y Kothari
- Y Li
- Y Maruyama
- Y Momiyama
- Y Ono
- Y Pan
- Y Sato
- Y Shibata
- Y Sun
- Y Watanabe
- Y Yao
- Y Yasaka
- Y Yoshida
- Y Zhang
- Y Zhang
- Y Zheng
- Z Bhatti
- Z Fan
- Z Mirza
- Z Sun
- Z Vomacka
- Z Yao
- Z Yousef
- Z Yuan
- Z Zheng
- Zannad F.
- Zeller C.
- Zhang J.
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2020
- Field of study
BACKGROUND Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes. More evidence is needed regarding the effects of these drugs in patients across the broad spectrum of heart failure, including those with a markedly reduced ejection fraction. METHODS In this double-blind trial, we randomly assigned 3730 patients with class II, III, or IV heart failure and an ejection fraction of 40% or less to receive empagliflozin (10 mg once daily) or placebo, in addition to recommended therapy. The primary outcome was a composite of cardiovascular death or hospitalization for worsening heart failure. RESULTS During a median of 16 months, a primary outcome event occurred in 361 of 1863 patients (19.4%) in the empagliflozin group and in 462 of 1867 patients (24.7%) in the placebo group (hazard ratio for cardiovascular death or hospitalization for heart failure, 0.75; 95% confidence interval [CI], 0.65 to 0.86; P<0.001). The effect of empagliflozin on the primary outcome was consistent in patients regardless of the presence or absence of diabetes. The total number of hospitalizations for heart failure was lower in the empagliflozin group than in the placebo group (hazard ratio, 0.70; 95% CI, 0.58 to 0.85; P<0.001). The annual rate of decline in the estimated glomerular filtration rate was slower in the empagliflozin group than in the placebo group (-0.55 vs. -2.28 ml per minute per 1.73 m2 of body-surface area per year, P<0.001), and empagliflozin-treated patients had a lower risk of serious renal outcomes. Uncomplicated genital tract infection was reported more frequently with empagliflozin. CONCLUSIONS Among patients receiving recommended therapy for heart failure, those in the empagliflozin group had a lower risk of cardiovascular death or hospitalization for heart failure than those in the placebo group, regardless of the presence or absence of diabetes
Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients
- Author
- Abbott J. Dawn
- Abdullah S.
- Abib E.
- Ables L. R.
- Abrantes J. A. M.
- Acosta R.
- Adams A.
- Adams F.
- Adroer Martori R.
- Agafina A. S.
- Agaiby J. M.
- Aggarwala G.
- Agraou B.
- AguilarSalinas C. A.
- Ahmad A.
- Ajala B.
- Akdeniz B.
- Akhtar N.
- Akright L.
- Aksentiev S.
- Al-Zoebi A.
- Alappat P.
- Albert M.
- Alfieri A. D.
- Alhakim M.
- Allaw M. A.
- Alpizar-Salazar M.
- Altafullah I. M.
- Alvarado O. P.
- Alvarez C. A.
- Alvarez J. G.
- Alvarez M. S.
- Alvarez-Sala Walther L. A.
- Alves A. R.
- Alwine L. K.
- Alzand B.
- Amarenco P.
- Ambrovicova V.
- Amerena J.
- Andersen J. L.
- Andersen L. T.
- Anderson Patricia
- Anderson T. J.
- Andrassy P.
- Andrei L. D.
- Andreka P.
- Angoulvant D.
- Angun M.
- Annamalai N.
- Ansari S. H.
- Anselmi M.
- Antonicelli R.
- Appel K. F.
- Aracil Villar J.
- Arain S.
- Arambula R. M. S.
- Araz M.
- Arca M.
- Arcanese M. L.
- Arden C.
- Areas C. A. F.
- Ari H.
- Ariani M. K.
- Arif I.
- Aroney C.
- Aronson R.
- Arstall M.
- Arstila L.
- Arya K. W.
- Asamoah-Owusu N.
- Askonen K.
- Aslam A. A.
- Assadourian A.
- Atar S.
- Auriel E.
- Avaca H.
- Averna M.
- Avornyo A. A.
- Avram R. I.
- Axthelm C.
- Ayesu K.
- Aylward P. E.
- Ayoub J. C. A.
- Baar M.
- Babapulle M.
- Badat A. E.
- Bailey S. R.
- Bajaj H.
- Bajcsi D.
- Baker J.
- Bakhai A.
- Baldari D.
- Ball E. M.
- Ballantyne C. M.
- Ballyuzek M.
- Balo T.
- Banaszkiewicz K.
- Banerjee M.
- Banik M.
- Banyai M.
- Baranova E.
- Barbarash O. L.
- Barbieri D. S. G.
- Barettella M. B.
- Barker B. A.
- Barnum O.
- Barreda Gonzalez M. J.
- Barrera C. M.
- Barrington P.
- Baultrukonis Dan
- Bax W. A.
- Bayat J.
- Bayron C. J.
- Bays H. E.
- Beaudry P.
- Beckett P. L.
- Begg A.
- Behmanesh B.
- Behnke T.
- Belenkiy D. I.
- Belicova M.
- Bellido Guerrero D.
- Bellingar B.
- Beltran L. G. M.
- Benacka J.
- Benatar J. R.
- Benczur B.
- Benitez O.
- Benjamin S. A.
- Berenguer R. A.
- Bergeron J.
- Bergerot C.
- Berk M. R.
- Berli M.
- Berlingieri J. C.
- Bernard J. V.
- Berrouschot J.
- Bertolet B. D.
- Bhindi R.
- Bianco H. T.
- Bijata-Bronisz R.
- Bilz S.
- Bittar G. D.
- Bitzur R.
- Bjasker K. R.
- Blach E.
- Black Henry
- Blagden M. D.
- Blaha V.
- Blake Gavin
- Blanco Coronado J. L.
- Blaze K.
- Blignault S. C.
- Blokhin A.
- Bloom S. A.
- Bocek P.
- Bod E.
- Bogaard K.
- Bogdanov E.
- Bokern M. J.
- Boman K.
- Bonansea T. C. P.
- Bonfanti J. A. C.
- Bonner J. H.
- Bonora E.
- Boonyavarakul A.
- Borer Jeffrey S.
- Botas Rodrigues J.
- Botelho R. V.
- Botella Serrano M.
- Botero-Lopez R.
- Botta C. E.
- Bourgeois R.
- Bourhaial H.
- Boye A.
- Boyett B. E.
- Brandon D. M.
- Brar H. S.
- Brauer C.
- Bravo P.
- Bredlau C. E.
- Breedveld R. W.
- Brenner H.
- Breton C. F.
- Bretton E. M.
- Brian Brian
- Brito Sanfiel M. A.
- Broncel M.
- Brotons Cuixart C.
- Broughton R.
- Bruguera Cortada Jordi
- Brunell R.
- Bruno R. L.
- Budassi N.
- Budoff M. J.
- Bueno Diez M.
- Bufka V.
- Buganova I.
- Bulanova N.
- Buonanno Marjorie
- Burgess L. J.
- Burnier M.
- Burova N.
- Busch R. S.
- Busegeanu M.
- Butuk D. J.
- Buynak R. J.
- Buysschaert I.
- Bybee K. A.
- Cabella P. R. F.
- Cabezas M. C.
- Caccavo A.
- Calin A.
- Calvo Gomez C.
- Camp A. D.
- Capiau L.
- Caputo R. P.
- Caramori P. R.
- Carlier M.
- Carlier S. G.
- Carmena Rafael
- Carnero G. S.
- Carroll P. A.
- Casabella T. E. S.
- Casaubon L.
- Castro Montes B. E.
- Castro M. A.
- Castro N. M. S.
- Catano J. S. V.
- Caudmont S.
- Cayla G.
- Cech V.
- Cecil J. T.
- Cequier Fillat A. R.
- Cerci R.
- Ceska R.
- Ceyhan C.
- Cha J. Y.
- Chahin M.
- Chakrabarti Anjan
- Chambers J. D.
- Chandna H.
- Chang A. R.
- Chang K-C
- Changlani M.
- Chati Z.
- Chaudhuri Sandip
- Cheek H. B.
- Chen J.
- Chen J. C.
- Cherlin R. S.
- Chernyatina M. A.
- Cheung S. S.
- Chiang C-E
- Chilka S.
- Chiong R.
- Cho B. R.
- Cho Y-S
- Chochinov R. H.
- Chorin E.
- Chouinard G.
- Chueca Fernandez J. E.
- Chun Hyung
- Cifkova R.
- Ciomag R. M.
- Civeira Murillo F.
- Civeira F.
- Clark G. B.
- Clark R.
- Claudio J.
- Clemens P. C.
- Codutti O. R.
- Coetzer T. F.
- Cohen A. J.
- Cohen S. S.
- Coisne D.
- Collier D. J.
- Colombo H. R.
- Colquhoun D.
- Colquhoun David
- Comlekci A.
- Conde D. G.
- Conde Diego
- Cone C. L.
- Connelly T.
- Connery L.
- Contzen C.
- Conway J. R.
- Cools F.
- Copaci I.
- Corder C. N.
- Corin A.
- Cornett G. M.
- Couffinhal T.
- Cramer E.
- Crater T. A.
- Crean P.
- Crimmins D. S.
- Crisby M.
- Cropp Anne
- Cruz Fernandez J. M.
- Csanadi M. A.
- Cuadrado J. A.
- Cucher F. H.
- Cui G.
- Curiac D.
- Curto M.
- Cusimano S.
- Czarnecka D.
- d'Emden M.
- da Costa F. A.
- Dada F. A. T.
- Dahl C. F.
- Dan G. A.
- Dan Gheorghe-Andrei
- Dart A. M.
- Dave K. N.
- Davidovits Z.
- Davidsen F.
- Davidson E.
- Davis M. G.
- Davis S. M.
- Davis T.
- de Barros e Silva P. G. M.
- De Belder M.
- De Bruyne L.
- De Castro R.
- De La Cuesta Mayor C.
- De La Fuente R. A. L.
- de Lima e Silva F. A.
- De Looze F.
- De los Rios Ibarra M. O.
- de Mora Martin M.
- de Moraes J. B. X. Junior
- De Nooijer C.
- de Oliveira Paiva M. S. M.
- de Santos M. O. N.
- de Souza W. K. S. B.
- De Sutter J.
- De Wolf L.
- Deak L.
- Dearborn-Tomazos Jennifer
- Debroye C.
- DeCaigney S. C.
- Deck K.
- Decoulx E.
- Degertekin M.
- Dela Llana A.
- Delarche N.
- Delforge M. D.
- Delgado J. P.
- Delgado M. I.
- Demin A.
- Demirci D.
- den Hartog F. R.
- Denker P. S.
- Derwahl K-M
- Desai V.
- Descamps O. S.
- Desfontaines P.
- Desrosiers D.
- DeStefano P.
- Detweiler R. O.
- Di Gennaro J. P. A.
- Diaz J. L.
- DiGiovanna M. J.
- Diller P. M.
- Dimas A. L.
- Dion D.
- Distiller L. A.
- Dixon L.
- Dominguez Escribano J. R. R.
- Dominguez Lopez M.
- Donders S. H.
- Dor I.
- Dorsel T.
- dos Santos F. R.
- Doshi A.
- Douglas F.
- Dracoulakis M. D. A.
- Drapkina O. M.
- Drozdz J.
- Du Y.
- Dubrava J.
- Dufreny A.
- Dulkova K.
- Duplyakov D.
- Duprez D.
- Durakoglugil E.
- Duran Garcia S.
- Duris T.
- Dutra O. P.
- Dy J.
- Dyke C. K.
- Dzupina A.
- Eaves W. B.
- Ebrahim I. O.
- Edes Istvan
- Edris M. A.
- Egstrup K.
- Eitan A.
- El Hafi S. E.
- El-Shahawy M.
- Elbaz M.
- Elbl L.
- Elegeert I.
- Eliaschewitz F. G.
- Elis A.
- Elizondo Moreno E. R.
- Ellison H. S.
- Elosegui A. M.
- Emanuel S.
- Engelbrecht I. V.
- Engelbrecht J. M.
- Epsley Charlotte
- Eraso A. M.
- Erkan A. F.
- Eryshev S.
- Escudier Villa J. M.
- Esperon G. A. L.
- Essandoh L. K.
- Estevez R.
- Estol C. C. C. J.
- Evans Barbara
- Fabryova L.
- Faes D.
- Fagan T. C.
- Faghih M.
- Fahdi I. E.
- Farago K.
- Farhat N. Z.
- Farias E. F.
- Farias F. A. Bandeira e
- Farris N. R.
- Farsad R.
- Fazekas F.
- Fedacko J.
- Fedele F.
- Feldman J.
- Felicio J. S.
- Felix S.
- Felten W. R.
- Ferkl R.
- Fernandez A. A.
- Ferrari E.
- Fialkow J. A.
- Field A.
- Field J. C.
- Figueiredo E. L.
- Figueras Camos R.
- Figueroa-Cruz W. L.
- Filardi P. P.
- Filho F. V. Guimaraes
- Filippov A.
- Fiore G.
- First B. P.
- Fiserova N.
- Fishbein G. J.
- Fitz-Patrick D.
- Flather M.
- Flores E.
- Fonseca F. A. H.
- Foody Joanne
- Fordan S.
- Forgosh L. B.
- Fortes J. A. R.
- Fouche L.
- Fox K. E.
- Fragoso V. G.
- Franceschini E.
- Francyk D. M.
- Franczek S.
- Fraser N. J.
- Frederich Robert
- French W. J.
- Frias J. J.
- Frisoli A.
- Frolova Martina
- Frost L.
- Fruntelata A-G
- Fuchs S.
- Fujita Kayo
- Fulmer J. J.
- Funk G. S.
- Furie Karen L.
- Gabra N. W.
- Gabriel J. D.
- Galatius S.
- Gallo H. J. H.
- Gammon R. S.
- Ganesh S.
- Gao Runlin
- Garcia Castillo A.
- Garcia Diaz J. De Dios
- Garcia Hernandez P. A.
- Garcia Puig J.
- Garcia B.
- Garcia D. K.
- Garcia H. L.
- Garcia-Moll Marimon X.
- Garden P. I.
- Garzone Pamela
- Gaspar L.
- Gaudet D.
- Gavish D.
- Gaztambide Saenz M. S.
- Gelersztein E.
- Gelfand Eli
- Gelormini J.
- Geohas J. G.
- George A. R.
- Gerke S.
- Geskin G.
- Gibson J. M.
- Gilbert J. M.
- Gilfillan C. P.
- Gilford T.
- Gillespie E.
- Gilmore R. M.
- Gimness M. P.
- Ginzburg M.
- Glaser L. A.
- Gleason G. P.
- Glenny J. A.
- Glover R.
- Glynn R. J.
- Goetsch Martina
- Gogia H. S.
- Goisse M.
- Goktekin O.
- Goldenberg R. M.
- Goldhaber A.
- Goloshchekin B. M.
- Gomez J. E. F.
- Gomez N. I. J.
- Gonzalbez Morgaez J. D.
- Gonzalez Juanatey C.
- Gonzalez Juanatey J. R.
- Gonzalez E. J.
- Gonzalez-Gonzalez J. G.
- Gonzalez-Ortiz M.
- Gordeev I. G.
- Gordon M. B.
- Gorman T. A.
- Gorog D. A.
- Gorosito V. M.
- Gosselink M. A.
- Gottlieb D. W.
- Gottsater A.
- Goube P.
- Goyes A. R. B.
- Graff A.
- Grant D. C.
- Green C. B.
- Gregoire J.
- Gregoire J. C.
- Gregoire Jean
- Greiff J.
- Grillo R. S.
- Grobbee Diederick
- Grodman R.
- Groenemeijer B. E.
- Grosman I.
- Groutars R. G. E. J.
- Guarnieri T. T.
- Guenzel A.
- Guerrero R. A. A.
- Guice M. J.
- Gullu H.
- Gumbiner Barry
- Gunstone A. E.
- Gupta A. K.
- Gupta D. K.
- Gupta N.
- Gutmann J. E.
- Haddad T. M.
- Hagemann D.
- Hagstrom E.
- Hajdu C.
- Hala T.
- Halcox J.
- Halperin F. A.
- Hamilton M. E.
- Hamroff G. S.
- Harding Sc A.
- Hart H. H.
- Hartleib M. C.
- Hartley P. A.
- Hartman A. N.
- Hassink R. J.
- Hastings W. L.
- He Y.
- Heijmans S.
- Heijmeriks J. A.
- Heisters J.
- Hellig F. S.
- Helm R. J.
- Henderson D. A.
- Hendrix E. L.
- Hengstenberg C.
- Her S-H
- Herdy A. H.
- Hermans K.
- Hermans W. R.
- Hermany P. R.
- Hernandes M. E.
- Hernandez Garcia J. M.
- Herrera-Marmolejo M.
- Herrington D. M.
- Herrman J-P R.
- Herrmann H-J
- Herrod J. N.
- Hershson A. R.
- Hessinger Diane
- Hiotis L.
- Hissa M.
- Hoag G. N.
- Hoedemaker G.
- Hof-Wiersma J. J. Van Het
- Hoffman A. S.
- Hoffman D. A.
- Hollanders G.
- Hoogslag P. A.
- Hook M.
- Horacek T.
- Horodecki M.
- Horowitz B. S.
- Hou C.
- Hovingh G. K.
- Hranai M.
- Humaloja K.
- Hurling R. T.
- Hussein O.
- Hutyra M.
- Hwang Juey-Jen
- Iglesias C.
- Ikehara Edson
- Illies G.
- Imai Keiji
- Imholz B. P.
- Incer C. S.
- Inzerello A. T.
- Isserman S. M.
- Isunza J. M. R.
- Ivan P.
- Ivanac Karen
- Jacks R. K.
- Jackson B.
- Jacoby Daniel
- Jacovides A.
- Jadbabaie Farid
- Jaffrani N.
- Jagielo T. J.
- Jamidar H. A.
- Janik M. J.
- Janion M.
- Janssens S.
- Jantzi C. M.
- Jattin F. G. M.
- Jayasinghe R.
- Jensen Henrik Kjaerulf
- Jeon H. K.
- Jeppensen J.
- Jepsen J. M.
- Jeserich M.
- Jhund P. S.
- Jiang J.
- Jimenez Hernandez M. D.
- Jimenez-Sanchez M.
- Jintapakorn W.
- Jodar Gimeno E.
- Joensen A.
- Johnson Margot
- Jones A. F.
- Joshi P. H.
- Jukema J. W.
- Jure H. O.
- Kadr H. H.
- Kahan Thomas
- Kaluski E.
- Kamensky G.
- Kamphuisen P. W.
- Kandath D. D.
- Kanderkova D.
- Kang W-C
- Kantola I.
- Karim S. N.
- Karlsbergg R. P.
- Karpov Y.
- Kastelein J. J. P.
- Kaster Sr
- Katelnitskiy I.
- Katz A.
- Kay J. S.
- Kayikcioglu M.
- Kekki S.
- Kelberman M.
- Kellnerova I.
- Kemeny V.
- Kennett J. D.
- Kentgens S.
- Kereiakes D. J.
- Kerr J.
- Kesani M. K.
- Keuleers S.
- Khaisheva L.
- Khalili P.
- Khari J.
- Khariouzov A.
- Khasanov N.
- Khokhlov A. L.
- Khurana S.
- Kiatchoosakun S.
- Kim C.
- Kim C. Y.
- Kim D-K
- Kim D. H.
- Kim K-S
- Kim K.
- Kim M. H.
- Kim S. H.
- Kimmel M. A.
- Kinnaman S. J.
- Kinzfogl G.
- Kipgen W.
- Kirby W. E.
- Kirschner R.
- Kizko Jan
- Klausen C.
- Klecha A.
- Klein C.
- Klein G.
- Klein J. J.
- Kleinecke-Pohl U.
- Knickelbine T.
- Knobler H.
- Knutson T. J.
- Kobielusz-Gembala I.
- Koenig W.
- Kohler A.
- Koilpillai R. N.
- Kokles M.
- Kolodziejczyk J.
- Kondagunta V.
- Konieczynska M.
- Konstantinov V.
- Korecki J.
- Kormann A. P. M.
- Kornmann M. O.
- Kosinski E. J.
- Koskinen P.
- Koskinen P. T.
- Kosmacheva E.
- Kosmider M.
- Kostenko V. A.
- Kostis J. B.
- Koszegi Z.
- Kotek L. W.
- Kotze H. J.
- Kouz S. M.
- Kracoff O. H.
- Krahulec B.
- Krawczyk J.
- Krichmar P.
- Krittayaphong R.
- Krolikowski Z.
- Kroon A. A.
- Kubalski P.
- Kuchar L.
- Kucharska D.
- Kuijper A. F.
- Kuzin A.
- Kuznetsov V. A.
- Kycina P.
- Labissiere J-C
- Labroo A.
- Lai W-T
- Lain E. L.
- Lakatos F.
- Landa K.
- Landron-Garcia L.
- Landzberg J. S.
- Larnefeldt H.
- Larsen D. C.
- Lassus J.
- Laszlo Z.
- Lauer B.
- Laufs U.
- Le Kim
- Leaes P. E.
- Lechuga Martin del Campo A.
- Ledesma G.
- Lee C. W.
- Lee Cheol Whan
- Lee M. W.
- Lee S. Y.
- Lefebvre G. C.
- Lehman R.
- Leichter S. B.
- Leiva Pons Jose Luis
- Lemke B.
- Lemmens R. C.
- Lenderink T.
- Lenhard M. J. J.
- Lentz J. D.
- Lepage S.
- Lepor N. E.
- Lerman S.
- Levinson D. J.
- Levisetti Matteo
- Levola J.
- Lewis B. S.
- Li D.
- Li J.
- Li S.
- Li W.
- Li Y.
- Lian Y.
- Libov I. A.
- Licka M.
- Liem S-S
- Lihn A. S.
- Lillestol M. J.
- Lim E. H.
- Linderfalk C.
- Lindgren L. M.
- Lindholm C-J
- Lip G.
- Lipetz R. S.
- Liu F.
- Llerena S. N.
- Lomakin N.
- Lomholdt Js
- Lopez Cano C.
- Lopez Rosas E.
- Lorenzatti A.
- Lotan Chaim
- Louwerenburg J. W.
- Lovell J. P.
- Loy J.
- Lozno H. Y.
- Luedemann J.
- Lukac M.
- Lukaszewicz M.
- Luna Ceballos R. I.
- Lupkovics G.
- Lupovitch S.
- Luquez H. A.
- Luts A.
- Ma Y.
- Maaieh M.
- MacDolnald L.
- Macek V.
- Mach F.
- Machkova M.
- Mackinnon I. J.
- MacNeill B.
- Madu I-J
- Maffei L. E.
- Maggiolini S.
- Maggioni Aldo
- Magro M.
- Mahal S. S.
- Mahomed A. A.
- Mahon N. G.
- Maia L. N.
- Mairuhu A. T.
- Maisterra Santos O.
- Makam S. K.
- Maldonado N.
- Malik A.
- Malygin A.
- Mandviwala M.
- Manenti E. R.
- Manga P.
- Mangili O. C.
- Manning M. B.
- Manoj A.
- Marar I. E.
- Margoczy R.
- Markovic T. P.
- Marshall A.
- Marten I.
- Martens F. M. A. C.
- Martin S.
- Martinez Deben F.
- Martinez Via L.
- Martinez L. M.
- Martinez R. F.
- Martinka E.
- Martorell Mateu E.
- Martyin T.
- Masana L.
- Masiukiewicz U.
- Maskova P.
- Masri B. E.
- Maus O.
- Maw K.
- Maximov D. M.
- Maxwell T. G.
- May O.
- Mayfield R. K.
- Maynard K. M.
- McAdam B.
- McCartney M. J.
- McCormack T.
- McCullough Louise
- McCullough P. A. A.
- McGarvey J. F.
- McGrew F.
- McKaig G.
- McKenzie M. E.
- McLean B.
- McMurray John
- McNally-Dufort Christine
- McNamara Robert
- McNeil D. L.
- McPherson Craig
- McPherson T. P.
- Mediavilla Garcia J. D.
- Medrano Martinez V.
- Mego D. M.
- Mehta P. M.
- Mellbin Linda
- Mello Y. G.
- Melucci M. B.
- Mendez Bucio A.
- Mendoza J. A.
- Michalaros Y. L.
- Micik J.
- Miekus P.
- Mierzejewski L.
- Mikusova T.
- Millar-Corte G. D.
- Miller A. B.
- Miller A. P.
- Miller M.
- Minescu B.
- Miranda A. A.
- Mirek-Bryniarska E.
- Miserez A. R.
- Missault L. H.
- Missault Luc
- Mistodie C. V.
- Moccetti T.
- Mociran M.
- Molin C. J.
- Molina C. A. A.
- Mollerus M. E.
- Molto-Jorda J. M.
- Monhart Z.
- Montalescot Gilles
- Montana O.
- Montenegro E. E.
- Montero M.
- Montgomery B.
- Mooe T.
- Moon E.
- Mootoo K. I.
- Mora A.
- Morales Portillo C.
- Morales-Villegas E.
- Moran G.
- Morcos N. C.
- Moriarty A.
- Moriarty P. M.
- Morocco Tamara
- Morocutti G.
- Morosanu M.
- Morris F. H.
- Morytko J. A.
- Mosenzon O.
- Mosseri M.
- Mosterd A.
- Motylev I.
- Mridha Khurshid
- Mudra H.
- Mukherjee A.
- Mulder H.
- Mulleners T.
- Muller C.
- Multani P.
- Muniz Grijalvo O.
- Munoz C. F. J.
- Munoz F.
- Munteanu M.
- Murcia A.
- Murin J.
- Musungaie D. B.
- Myhill T.
- Nadkarni Sharayu
- Nadra I. J.
- Nagy A.
- Nagy K.
- Nagy L.
- Nair D. R.
- Nakandakare E. R.
- Nanchen D.
- Nanji A.
- Napoli M. C.
- Narayan P.
- Narejos S.
- Nascimento C. V.
- Nash M. L.
- Nashed A. N.
- Naudts I.
- Neaton James
- Necki M.
- Nedoshivin A.
- Negrisanu G. D.
- Nerg O.
- Neuenschwander F. C.
- Nguyen T.
- Nicol P. R.
- Nicolau J. C.
- Nielesen T.
- Nielsen W. B.
- Nierop P. R.
- Nijmeijer R.
- Nikolaev K. Y.
- Nisnisan J. M.
- Nissen S.
- Nissen Thor
- Nixon W. A.
- Noble Stephane
- Nociar J.
- Northroff J.
- Norwood P. C.
- Nseir W. B.
- Nuriulu Escobar P. L.
- Nye Regina
- O'Dea D. J.
- O'Mahoney M.
- O'Neill Blair
- O'Steen M. B.
- Ochala A.
- Odekirk L. L.
- Okopien B.
- Oleynikov V.
- Ong S. T.
- Onrat E.
- Opalinska E.
- Orkwiszewska-Nalewajko A.
- Oroszlan T.
- Ostrowski J.
- Ovalle F.
- Owen J. G.
- Ozcan T.
- Pacheco T. R.
- Paillard F.
- Pak Raphael
- Palchick B. A.
- Palomaki A.
- Panchenko E.
- Pandey S.
- Pantaleoni M.
- Papp A.
- Paraboschi C. F.
- Paragh G.
- Pasechnik E.
- Pasqualini L.
- Pasquini J. A.
- Pasternak D. A.
- Pastrnakova E.
- Patel A. M.
- Patle R.
- Peart B. C.
- Pegge N.
- Pei D.
- Pelaez S. V.
- Pella D.
- Pence Debbie
- Peniston J. H.
- Pereira E. S.
- Perez Martinez P.
- Perez Paredes M.
- Perez J. A.
- Perings C.
- Perlman R. L.
- Perloff D. E.
- Persson B. E.
- Pesant Y.
- Peterfai E.
- Peters S. S.
- Peterson S. R.
- Petit C.
- Petrella J.
- Pfuetzner A.
- Pham D. N.
- Piazza Gregory
- Piepiorka M.
- Pierpoint B. E.
- Pijanowski Z.
- Pinto Sala X.
- Pinto Duane
- Piovaccari G.
- Pirro M.
- Piskorz-Wapinska J.
- Plaza Perez I.
- Plazas J. A. R.
- Pliamm L.
- Plowchalk David
- Pluto T. M.
- Pock J.
- Pohlmeier L.
- Polanczyk C. A.
- Ponikowski P.
- Pons Amate J. M.
- Pop C. F.
- Popa A. R.
- Popescu A.
- Popescu M.
- Popescu M. L.
- Popov D.
- Popova V. B.
- Popoviciu M. S.
- Porcu M.
- Post J. C.
- Pouzar J. E.
- Powell Coralie
- Prasada S.
- Precoma D. B.
- Pretorius C. E.
- Pretorius M. M.
- Price D.
- Pride Yuri
- Probst V.
- Proepper F.
- Proietto J.
- Promisloff S. D.
- Pryke J. R.
- Przekwas-Jaruchowska M.
- Pudi K. K.
- Puhakka M.
- Purdy D. A.
- Purnell P. W.
- Quraishi A. M.
- Quyyumi A. A.
- Rabahi F.
- Radin D. M.
- Radoi M.
- Rai A.
- Ramos H. R.
- Ramos M. J.
- Ramos S. A. J.
- Ramos-Lopez G. A.
- Ramstad D. S.
- Randall W. J.
- Randhawa P. M.
- Range G.
- Ranjith N.
- Raoof T. J.
- Raslova K.
- Rasmanis G.
- Rasmussen T. K.
- Rech R. L.
- Reddy R. D.
- Redifer Patricia
- Reed R.
- Reedy M. A.
- Reiber I.
- Reis G.
- Remmen J. J.
- Rendell M. S.
- Rensing B. J.
- Resende E. S.
- Reshetko O.
- Resk J. H.
- Revkin J.
- Revkin Jim
- Reyes R. G.
- Reyna L. S.
- Reynolds R. D.
- Rhee M. Y.
- Rhudy J. M.
- Rice S.
- Rickers H.
- Rico-Carrillo A. E.
- Rictor K. W.
- Ridker P. M.
- Riesenberg R. A.
- Rigolosi R.
- Rihani R.
- Riksen N. P.
- Rim S. J.
- Rinke A.
- Riojas Charles C. M.
- Ripoll Vera T. V.
- Risser J. A.
- Ritt L. E. F.
- Robertson D. G.
- Robinson J. G.
- Robinson M. F.
- Robles Iniesta A.
- Rocco M. B.
- Rodriguez I. J.
- Rodriguez W. R. B.
- Rodriguez-Briones I.
- Roman G.
- Romer T. J.
- Romero Hinojosa J. A.
- Roncon L.
- Ronner E.
- Roos J. S.
- Roosen J.
- Roquer Gonzalez J.
- Rosenfeld J. C.
- Rosenstock J.
- Roskova E.
- Rossi P. R. F.
- Roubille F.
- Roux S. M.
- Rozpondek P.
- Rubenfire M.
- Ruiz L. A. N.
- Ruiz-R L.
- Ruoff G. E.
- Rusculleda M. M.
- Rusicka T.
- Russo L. A.
- Saad J. A.
- Sachson R. A.
- Sack G.
- Saeed S.
- Sahin T.
- Sahul Z. H.
- Saini S.
- Sala J.
- Salacata A.
- Salbach P.
- Saldeen-Nilehn K.
- Salter T. J.
- Salvioni A.
- Samoylova Y. G.
- Sanchez Alvarez J.
- Sanchez Mijangos J. H.
- Sanchez M. L. J.
- Sandberg J. H.
- Sansing Lauren H.
- Santos R. D.
- Saporito W. F.
- Saraiva J. F. K.
- Sarens T.
- Sari R.
- SaryuszWolska M.
- Sasson Stephen
- Sathyapalan T.
- Sattler Catherine
- Saunders K. K.
- Savin V.
- Savolainen M.
- Savolainen Markku
- Savonitto Stefano
- Saxena S.
- Schaap J.
- Schade Robin
- Schaefer A.
- Schaufele T.
- Scheen A.
- Schiele F.
- Schiele Francois
- Schifferdecker B.
- Schindler Joseph
- Schlager D.
- Schmedtje J. F.
- Schmidberg J.
- Schmidt E.
- Schmidt U.
- Schoell I.
- Scholz G.
- Schoofs M. W.
- Schoors D. F.
- Schou J. Bronnum
- Schou M.
- Schreuder T.
- Schroe H. H.
- Schuchard T. N.
- Schumacher D. R.
- Schwartz P. F.
- Schwartz Whitney
- Schwimmbeck P.
- Scott B. P.
- Scott D. L.
- Scott R. S.
- Searles G.
- Seaton B. L.
- Seep M. K.
- Segall N.
- Segura T.
- Seidman B.
- Sensebrenner J. W.
- Serje J.
- Sesti G.
- Sganzerla P.
- Shah S. A.
- Shalaev S. V.
- Shammas N.
- Shangina O. A.
- Shapovalova J.
- Sharir T.
- Sharma R.
- Sharma S.
- Shayani S. S.
- Sheahan D.
- Shear C. L.
- Shechter M.
- Shilkina N. P.
- Shimon I.
- Shivaswamy V.
- Shogenov Z. S.
- Shoukfeh M.
- Shultz J. H.
- Shutemova E.
- Shvarts Y.
- Sia S. M.
- Sibon I.
- Sidor M.
- Sigal H.
- Sillesen H.
- Silva R. P.
- Silverman Isaac E.
- Simanenkov V. I.
- Simon J.
- Singal D. K.
- Singh B.
- Singh S.
- Sitterli-Natea C. N.
- Skaggs Judy
- Skripova D.
- Smith P.
- Smith S. K.
- Smith W. B.
- Sobolewska J.
- Sobrino-Martinez J.
- Sogorb Garri F.
- Solar Miroslav
- Soler J. M. P.
- Solodky A.
- Solonev O.
- Somogyi A.
- Soosova I.
- Soran H.
- Soroka E.
- Sosa-Padilla M. A.
- Soto Gonzalez A.
- Soto J. R. L.
- Sotolongo R.
- Sotolongo R. P.
- Soufflet V.
- Sparks J.
- Spence J. D.
- Srimahachota S.
- Sritara Piyamitr
- Srivastava S.
- Staab P. K.
- StAmour E.
- Stamps H. B.
- Stawowy P.
- Steffensen R.
- Steinberg A. A.
- Steinhoff J. P.
- Stellbrink C.
- Stephan U. Da
- Sternieri M. V. B. B.
- Stevlik J.
- Stich M. A.
- Stobschinski C. A.
- Stoessel J.
- Stoller S. R.
- Strader J. R.
- Strain J. E.
- Strand J.
- Strandberg A.
- Stranks S. N.
- Stratmann M.
- Strbova J.
- Stringam S. O.
- Strobl D. J.
- Strzinek R. A.
- Stuckey T.
- Styczkiewicz M.
- Suarez Garcia S.
- Suarez-Fernandez C.
- Suarez-Sarmiento A.
- Sullivan Beth
- Sullivan D.
- Sultan S.
- Sumbal J.
- Suomi J.
- Supronik J.
- Suryanarayana P. G.
- Sutton J. C.
- Swart H. P.
- Sweeney Kevin
- Sydo T.
- Sykulski R.
- Szilagyi I.
- Taeschner H.
- Tahirkheli N. K.
- Tahk S-J
- Takhar A.
- Talano J. V.
- Tami L. F.
- Tan A. E.
- Tanne D.
- Tarasenko Lisa
- Tarasov N.
- Tardif J. -C.
- Tase A.
- Tatlisumak T.
- Taurio J.
- Taverna Llaurado E.
- Tayoum H.
- Teitelbaum I.
- Tellier G.
- Teltser M.
- Tengmark B-O
- Ternouth I. F.
- Terns Riera M.
- Terrelonge A. E.
- The S. H.
- Thoeng J.
- Thom S.
- Thompson P.
- Thomsen K. K.
- Thouvenot E.
- Ti Z.
- Tichelaar P.
- Timonen M.
- Tinahones Madueno F. J.
- Tivadar S.
- Tofe Povedano S.
- Tokgozoglu Lale
- Toldy-Schedel E.
- Tolkacheva V.
- Torre Amione G.
- Tortensson I.
- Toth K.
- Toth L.
- Townsend J. C.
- Traboulssi M. A.
- Treasure C. B.
- Trebacz J.
- Trenk D.
- Triana E. H.
- Trimarco B.
- Trippett J. M.
- Troquay R. P.
- Truban J.
- Tsai W-C
- Tsalihin D.
- Tumelero R.
- Tunon J.
- Turner T. A.
- Turner W.
- Twum-Barima D. Y.
- Ueng K-C
- Uhliar R.
- Ulla M. R.
- Underberg J. A.
- Updegrove J. D.
- Uresin Ali Yagız
- Urhammer S.
- Urina Miguel
- Urina-Triana M. A.
- Uusinarkaus K. T.
- Vaca C. E.
- Vahed Y. A. K.
- Valdez Lopez H. G.
- Valtonen M.
- Van Alem A. P.
- van Beek E.
- van Daele M. E.
- van de Borne P.
- van de Wal R. M. A.
- van de Wetering M. L.
- van de Wiel A.
- van der Meer P.
- van der Walt E.
- van der Zwaan C. T.
- Van Gaal W.
- van Hal J. M. C.
- van Kempen W. W.
- Van Koningsbruggen P.
- van Landegem P.
- van Leendert R. J.
- van Nieuwenhuizen E.
- van Resburg D. Jansen
- van Rossum P.
- van Royen N.
- van Zyl L. J.
- VanNatta B.
- Vanttinen E.
- Vazan A.
- Vazquez-Tanus J. B.
- Veenendaal A.
- Venereo J. M.
- Venter D. J.
- Verdeza C.
- Vertes A.
- Vervoort G.
- Verwerft J.
- Vesely J.
- Vico M. L.
- Viergever E. P.
- Viklund J.
- Vila Belmonte A.
- Villaman-Bencosme Y.
- Vinanska D.
- Vincent John
- Vincent S.
- Vinyoles Bargallo E.
- Violante Ortiz R.
- Vishlitzky V.
- Vishneva E.
- Visser Rieuwk P.
- Visseren F. L.
- Vivekananthan K.
- Vizel S.
- Vlach J. J.
- Vodnansky P.
- Voehringer H-F
- Vogel D. R.
- Vohnout B.
- Vojacek J.
- Volkova A.
- Voller H.
- von Engelhardt C. B.
- von Hodenberg E. F.
- Vora K. N.
- Vora S. K.
- Voros P.
- Vrablik M.
- Vrkoc J.
- Vukotic G.
- Wadud K.
- Wainstein J.
- Wakefield P. H.
- Wakeling J.
- Walczak M.
- Walczewska J.
- Walukiewica P.
- Wang D.
- Wang Ellen
- Wang G.
- Wang Y.
- Wasserburger B.
- Waxler A. R.
- Wayne J. D.
- Weber D.
- Weber K.
- Wegner John
- Wei Caimiao
- Weigmann I.
- Weinstein D. L.
- Weiss R.
- Welker J. A.
- Welty Francine
- Wenetz L. M. M.
- Wermuth S.
- Wesson T.
- West S. H.
- Westerndorp I.
- Wetzel T.
- White H.
- Whitlock L.
- Whitney R. T.
- Wiggers H.
- William M.
- Williams D. G.
- Williams M.
- Willis J. G.
- Willits V. L.
- Winkelmann B.
- Witt N.
- Wittmann I.
- Woehrle J.
- Worner Diz F.
- Wozniak I.
- Wright R. S.
- Wronska D.
- Wuerzner G.
- Wychota K.
- Xu P.
- Xue L.
- Yakusevich V. V.
- Yang P.
- Yang X.
- Yao L. C.
- Yared Z.
- Yarows S. A.
- Yigit Z.
- Yoon J.
- Yunis C.
- Zadra R.
- Zaidman C. J.
- Zamorano Gomez J. L.
- Zannad Faiez
- Zarandon R. B. S.
- Zarich S. W.
- Zateyshchikov D.
- Zavaro S. H.
- Zebrack J. S.
- Zeig S.
- Zemek S.
- Zemour G.
- Zeng X.
- Zeno M. L.
- Zhang L.
- Zhang X.
- Zhang Y.
- Zhao Y.
- Zhou C.
- Zhou Y.
- Zhu Y.
- Zidkova E.
- Zieba B.
- Zilahi Z.
- Zoet-Nugteren S. K.
- Zrazhevskiy K.
- Zubek V.
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
BACKGROUN
Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients
- Author
- A A
- Abbott Jd
- Abdullah S
- Abib E Jr
- Ables Lr
- Abrantes Ja
- Acosta R
- Adams A
- Adams F
- Adroer Martori R
- Agafina As
- Agaiby Jm
- Aggarwala G
- Agraou B
- Aguilarsalinas Ca
- Ahmad A
- Ajala B
- Akdeniz B
- Akhtar N
- Akright L
- Aksentiev S
- Al-Zoebi A
- Alappat P
- Albert M
- Alfieri Ad
- Alhakim M
- Allaw Ma
- Alpizar-Salazar M
- Altafullah Im
- Alvarado Op
- Alvarez Ca
- Alvarez Jg
- Alvarez Ms
- Alvarez-Sala Walther La
- Alves AR Jr
- Alwine Lk
- Alzand B
- Amarenco P.
- Ambrovicova V
- Amerena J
- Andersen Jl
- Andersen Lt
- Anderson P
- Anderson Tj
- Andrassy P
- Andrei Ld
- Andreka P
- Angoulvant D
- Angun M
- Annamalai N
- Ansari Sh
- Anselmi M
- Antonicelli R
- Appel Kf
- Aracil Villar J
- Arain S
- Arambula Rm
- Araz M
- Arca M
- Arcanese Ml
- Arden C
- Areas Ca
- Ari H
- Ariani Mk
- Arif I
- Aroney C
- Aronson R
- Arstall M
- Arstila L
- Arya Kw
- Asamoah-Owusu N
- Askonen K
- Aslam Aa
- Assadourian A
- Assef V
- Atar S
- Auriel E
- Avaca H
- Averna M
- Avornyo Aa
- Avram Ri
- Axthelm C
- Ayesu K
- Aylward Pe
- Ayoub Jc
- Baar M
- Babapulle M
- Badat Ae
- Bailey Sr
- Bajaj H
- Bajcsi D
- Baker J
- Bakhai A
- Baldari D
- Ball Em
- Ballantyne Cm
- Ballyuzek M
- Balo T
- Banaszkiewicz K
- Bandeira e Farias FA
- Banerjee M
- Banik M
- Banyai M
- Baranova E
- Barbarash Ol
- Barbieri Ds
- Barettella Mb
- Barker Ba
- Barnum O
- Barreda Gonzalez Mj
- Barrera Cm
- Barrington P
- Baultrukonis D
- Bax Wa
- Bayat J
- Bayron Cj
- Bays He
- Beaudry P
- Beckett Pl
- Begg A
- Behmanesh B
- Behnke T
- Belenkiy Di
- Belicova M
- Bellido Guerrero D
- Bellingar B
- Beltran Lg
- Benacka J
- Benatar Jr
- Benczur B
- Benitez O
- Benjamin Sa
- Berenguer Ra
- Bergeron J
- Bergerot C
- Berk Mr
- Berli M
- Berlingieri Jc
- Bernard Jv
- Berrouschot J
- Bertolet Bd
- Bhindi R
- Bianco Ht
- Bijata-Bronisz R
- Bilz S
- Bittar Gd
- Bitzur R
- Bjasker Kr
- Blach E
- Black H
- Blagden Md
- Blaha V
- Blake G
- Blanco Coronado Jl
- Blaze K
- Blignault Sc
- Blokhin A
- Bloom Sa
- Bocek P
- Bod E
- Bogaard K
- Bogdanov E
- Bokern Mj
- Boman K
- Bonansea Tc
- Bonfanti Ja
- Bonner Jh
- Bonora E
- Boonyavarakul A
- Borer Js
- Botas Rodrigues J
- Botelho Rv
- Botella Serrano M
- Botero-Lopez R
- Botta Ce
- Bourgeois R
- Bourhaial H
- Boye A
- Boyett Be
- Brandon Dm
- Brar Hs
- Brauer C
- Bravo P
- Bredlau Ce
- Breedveld Rw
- Brenner H
- Breton Cf
- Bretton Em
- Brito Sanfiel Ma
- Broncel M
- Bronnum Schou J
- Brotons Cuixart C
- Broughton R
- Bruguera Cortada J
- Brunell R.
- Bruno Rl
- Budassi N
- Budoff Mj
- Bueno Diez M
- Bufka V
- Buganova I
- Bulanova N
- Buonanno M
- Burgess Lj
- Burnier M
- Burova N
- Busch Rs
- Busegeanu M
- Butuk Dj
- Buynak Rj
- Buysschaert I
- Bybee Ka
- Cabella Pr
- Cabezas Mc
- Caccavo A
- Calin A
- Calvo Gomez C
- Camp Ad
- Capiau L
- Caputo Rp
- Caramori Pr
- Carlier M
- Carlier Sg
- Carmena R
- Carnero Gs
- Carroll Pa
- Casabella Te
- Casaubon L
- Castro Montes Be
- Castro Ma
- Castro Nm
- Catano Js
- Caudmont S
- Cayla G
- Cech V
- Cecil Jt
- Cequier Fillat Ar
- Cerci R
- Ceska R
- Ceyhan C
- Cha Jy
- Chahin M
- Chakrabarti A
- Chambers Jd
- Chandna H
- Chang Ar
- Chang Kc
- Changlani M
- Chati Z
- Chaudhuri S
- Cheek Hb
- Chen J
- Chen Jc
- Cherlin Rs
- Chernyatina Ma
- Cheung Ss
- Chiang Ce
- Chilka S
- Chiong R
- Cho Br
- Cho Ys
- Chochinov Rh
- Chorin E
- Chouinard G
- Chueca Fernandez Je
- Chun H
- Cifkova R
- Ciomag Rm
- Civeira Murillo F
- Civeira F.
- Clark Gb
- Clark R
- Claudio J
- Clemens Pc
- Codutti Or
- Coetzer Tf
- Cohen Aj
- Cohen Ss
- Coisne D
- Collier Dj
- Colombo Hr
- Colquhoun D
- Colquhoun D
- Comlekci A
- Conde Dg
- Cone Cl
- Connelly T
- Connery L
- Contzen C
- Conway Jr
- Cools F
- Copaci I
- Corder Cn
- Corin A
- Cornett Gm
- Cortada Jb
- Couffinhal T
- Cramer E
- Crater Ta
- Crean P
- Crimmins Ds
- Crisby M
- Cropp A
- Cruz Fernandez Jm
- Csanadi Ma
- Cuadrado Ja
- Cucher Fh
- Cui G
- Curiac D
- Curto M
- Cusimano S
- Czarnecka D
- D'Emden M
- da Costa Fa
- Da Stephan U
- Dada Fa
- Dahl Cf
- Dan Ga
- Dan Ga
- Dart Am
- Dave Kn
- Davidovits Z
- Davidsen F
- Davidson E
- Davis Sm
- Davis T
- de Barros e Silva PG
- De Belder M
- De Bruyne L
- De Castro R
- De Dios Garcia Diaz J
- De La Cuesta Mayor C
- De La Fuente Ra
- de Lima e Silva FA
- De Looze F
- De los Rios Ibarra Mo
- de Mora Martin M
- de Moraes Junior Jb
- De Nooijer C
- de Oliveira Paiva Ms
- de Santos Mo
- de Souza Wk
- De Sutter J
- De Wolf L
- Deak L
- Dearborn-Tomazos J
- Debroye C
- Decaigney Sc
- Deck K
- Decoulx E
- Degertekin M
- Dela Llana A
- Delarche N
- Delforge Md
- Delgado Jp
- Delgado Mi
- Demin A
- Demirci D
- den Hartog Fr
- Denker Ps
- Derwahl Km
- Desai V
- Descamps Os
- Desfontaines P
- Desrosiers D
- Destefano P
- Detweiler Ro
- Di Gennaro Jp
- Diaz Jl
- Digiovanna Mj
- Diller Pm
- Dimas Al
- Dion D
- Distiller La
- Dixon L
- Dominguez Escribano Jr
- Dominguez Lopez M
- Donders Sh
- Dor I
- Dorsel T
- dos Santos Fr
- Doshi A
- Douglas F
- Dracoulakis Md
- Drapkina Om
- Drozdz J
- Du Y
- Dubrava J
- Dufreny A
- Dulkova K
- Duplyakov D
- Duprez D
- Durakoglugil E
- Duran Garcia S
- Duris T
- Dutra Op
- Dy J
- Dyke Ck
- Dzupina A
- Eaves Wb
- Ebrahim Io
- Edes I
- Edes I
- Edris Ma
- Egstrup K
- Eitan A
- El Hafi Se
- El Shahawy M
- El-Shahawy M
- Elbaz M
- Elbl L
- Elegeert I
- Eliaschewitz Fg
- Elis A
- Elizondo Moreno Er
- Ellison Hs
- Elosegui Am
- Emanuel S
- Engelbrecht Iv
- Engelbrecht Jm
- Epsley C
- Eraso Am
- Erkan Af
- Eryshev S
- Escudier Villa Jm
- Esperon Ga
- Essandoh Lk
- Estevez R
- Estol Cc
- Evans B
- Fabryova L
- Faes D
- Fagan Tc
- Faghih M
- Fahdi Ie
- Farago K
- Farhat Nz
- Farias Ef
- Farris Nr
- Farsad R
- Fazekas F
- Fedacko J
- Fedele Francesco
- Feldman J
- Felicio Js
- Felix S
- Felten Wr
- Ferkl R
- Fernandez Aa
- Ferrari E
- Fialkow Ja
- Field A
- Field Jc
- Figueiredo El
- Figueras Camos R
- Figueroa-Cruz Wl
- Filardi Pp
- Filippov A
- Fiore G
- First Bp
- Fiserova N
- Fishbein Gj
- fitz-Patrick D
- Flather M.
- Flores E
- Fonseca Fa
- Foody J
- Fordan S
- Forgosh Lb
- Fortes Ja
- Fouche L
- Fox Ke
- Fragoso Vg
- Franceschini E
- Francyk Dm
- Franczek S
- Fraser Nj
- Frederich R
- French Wj
- Frias Jj
- Frisoli A
- Frolova M
- Frost L
- Fruntelata Ag
- Fuchs S
- Fujita K
- Fulmer Jj
- Funk Gs
- Furie Kl
- Gabra Nw
- Gabriel Jd
- Galatius S
- Gallo Hj
- Gammon Rs
- Ganesh S
- Gao R
- Garcia Castillo A
- Garcia Hernandez Pa
- Garcia Puig J
- Garcia B
- Garcia Dk
- Garcia Hl
- Garcia-Moll Marimon X
- Garden Pi
- Garzone P
- Gaspar L
- Gaudet D
- Gavish D
- Gaztambide Saenz Ms
- Gelersztein E
- Gelfand E
- Gelormini J
- Geohas Jg
- George Ar
- Gerke S
- Geskin G
- Gibson Jm
- Gilbert Jm
- Gilfillan Cp
- Gilford T
- Gillespie E
- Gilmore Rm
- Gimness Mp
- Ginzburg M
- Glaser La
- Gleason Gp
- Glenny Ja
- Glover R
- Glynn R. J.
- Godoy Jg
- Goetsch M
- Gogia Hs
- Goisse M
- Goktekin O
- Goldenberg Rm
- Goldhaber A
- Goloshchekin Bm
- Gomez Je
- Gomez Ni
- Gonzalbez Morgaez Jd
- Gonzalez Juanatey C
- Gonzalez Juanatey Jr
- Gonzalez Ej
- Gonzalez-Gonzalez Jg
- Gonzalez-Ortiz M
- Gordeev Ig
- Gordon Mb
- Gorman Ta
- Gorog Da
- Gorosito Vm
- Gosselink Ma
- Gottlieb Dw
- Gottsater A
- Goube P
- Goyes Ar
- Graff A
- Grant Dc
- Green Cb
- Gregoire J.
- Gregóire Jc
- Greiff J
- Grillo Rs
- Grobbee D
- Grodman R
- Groenemeijer Be
- Grosman I
- Groutars Rg
- Grégoire J
- Guarnieri Tt
- Guenzel A
- Guerrero Ra
- Guice Mj
- Guimarães Filho Fv
- Gullu H
- Gumbiner B
- Gunstone Ae
- Gupta Ak
- Gupta Dk
- Gupta N
- Gutmann Je
- Haddad Tm
- Hagemann D
- Hagstrom E
- Hajdu C
- Hala T
- Halcox J
- Halperin Fa
- Hamilton Me
- Hamroff Gs
- Harding Sa
- Hart Hh
- Hartleib Mc
- Hartley Pa
- Hartman An
- Hassink Rj
- Hastings Wl
- He Y
- Heijmans S
- Heijmeriks Ja
- Heisters J
- Hellig Fs
- Helm Rj
- Henderson Da
- Hendrix El
- Hengstenberg C
- Her Sh
- Herdy Ah
- Hermans K
- Hermans Wr
- Hermany Pr
- Hernandes Me
- Hernandez Garcia Jm
- Herrera-Marmolejo M
- Herrington Dm
- Herrman Jp
- Herrmann Hj
- Herrod Jn
- Hershson Ar
- Hessinger D
- Hiotis L
- Hissa M
- Hoag Gn
- Hoedemaker G
- Hoffman As
- Hoffman Da
- Hollanders G
- Hoogslag Pa
- Hook M
- Horacek T
- Horodecki M
- Horowitz Bs
- Hou C
- Hovingh Gk
- Hranai M
- Humaloja K
- Hurling Rt
- Hussein O
- Hutyra M
- Hwang Jj
- Hwang Jj
- Iglesias C
- Ikehara E
- Illies G
- Imai K
- Imholz Bp
- Ince CS Jr
- Inzerello At
- Isserman Sm
- Isunza Jm
- Ivan P
- Ivanac K
- J. -C. Conde D
- Jacks Rk
- Jackson B
- Jacoby D
- Jacovides A
- Jadbabaie F
- Jaffrani N
- Jagielo Tj
- Jamidar Ha
- Janik Mj
- Janion M
- Jansen van Resburg D
- Janssens S
- Jantzi Cm
- Jattin Fg
- Jayasinghe R
- Jensen Hk
- Jeon Hk
- Jeppensen J
- Jepsen Jm
- Jeserich M
- Jhund Ps
- Jiang J
- Jimenez Hernandez Md
- Jimenez-Sanchez M
- Jintapakorn W
- Jodar Gimeno E
- Joensen A
- Johnson M
- Jones Af
- Joshi Ph
- Jrdavis Mg
- Jrquraishi Am
- Jukema J. W.
- Jure Ho
- Kadr Hh
- Kahan T
- Kahan T
- Kaluski E
- Kamensky G
- Kamphuisen Pw
- Kandath Dd
- Kanderkova D
- Kang Wc
- Kantola I
- Karalis I
- Karim Sn
- Karlsbergg Rp
- Karpov Y.
- Kastelein J. J. P.
- Kaster S
- Katelnitskiy I
- Katz A
- Kay Js
- Kayikcioglu M
- Kekki S
- Kelberman M
- Kellnerova I
- Kemeny V
- Kennett Jd
- Kentgens S
- Kereiakes Dj
- Kerr J
- Kesani Mk
- Keuleers S
- Khaisheva L
- Khalili P
- Khari J
- Khariouzov A
- Khasanov N
- Khokhlov Al
- Khurana S
- Kiatchoosakun S
- Kim C
- Kim Cy
- Kim Dh
- Kim Dk
- Kim K
- Kim Ks
- Kim Mh
- Kim Sh
- Kimmel Ma
- Kinnaman Sj
- Kinzfogl G
- Kipgen W
- Kirby We
- Kirschner R
- Kizko J
- Klausen L
- Klecha A
- Klein C
- Klein G
- Klein Jj
- Kleinecke-Pohl U
- Knickelbine T
- Knobler H
- Knutson Tj
- Kobielusz-Gembala I
- Koenig W.
- Kohler A
- Koilpillai Rn
- Kokles M
- Kolodziejczyk J
- Kondagunta V
- Konieczynska M
- Konstantinov V
- Korecki J
- Kormann Ap
- Kornmann Mo
- Kosinski Ej
- Koskinen P
- Koskinen Pt
- Kosmacheva E
- Kosmider M
- Kostenko Va
- Kostis Jb
- Koszegi Z
- Kotek Lw
- Kotze Hj
- Kouz Sm
- Kracoff Oh
- Krahulec B
- Krawczyk J
- Krichmar P
- Krittayaphong R
- Krolikowski Z
- Kroon Aa
- Kubalski P
- Kuchar L
- Kucharska D
- Kuijper Af
- Kuzin A
- Kuznetsov Va
- Kycina P
- Labissiere Jc
- Lai Wt
- Lain El
- Lakatos F
- Landa K
- Landron-Garcia L
- Landzberg Js
- Larnefeldt H
- Larsen Dc
- Lassus J
- Laszlo Z
- Lauer B
- Laufs U
- Le K
- Leaes Pe
- Lechuga Martin del Campo A
- Ledesma G
- Lee Cw
- Lee Cw
- Lee Mw
- Lee Sy
- Lefebvre Gc
- Lehman R
- Leichter Sb
- Leiva Pons Jl
- Leiva Pons Jl
- Lemke B
- Lemmens Rc
- Lenderink T
- Lenhard Mj
- Lentz Jd
- Lepage S
- Lepor Ne
- Lerman S
- Levinson Dj
- Levisetti M
- Levola J
- Lewis Bs
- Li D
- Li J
- Li S
- Li W
- Li Y
- Lian Y
- Libov Ia
- Licka M
- Liem Ss
- Lihn As
- Lillestol Mj
- Lim Eh
- Linderfalk C
- Lindgren Lm
- Lindholm Cj
- Lip G
- Lipetz Rs
- Liu F
- Llerena Sn
- Lomakin N
- Lomholdt J
- Lopez Cano C
- Lopez Rosas E
- Lorenzatti A.
- Lotan C
- Lotan C
- Louwerenburg Jw
- Lovell Jp
- Loy J
- Lozno Hy
- Luedemann J
- Lukac M
- Lukaszewicz M
- Luna Ceballos Ri
- Lupkovics G
- Lupovitch S
- Luquez Ha
- Luts A
- Ma Y
- Maaieh M
- Macdolnald L
- Macek V
- Mach F
- Machkova M
- Mackinnon Ij
- Macneill B
- Madu Ij
- Maffei Le
- Maggiolini S
- Maggioni A
- Magro M
- Mahal Ss
- Mahomed Aa
- Mahon Ng
- Maia Ln
- Mairuhu At
- Maisterra Santos O
- Makam Sk
- Maldonado N
- Malik A
- Malygin A
- Mandviwala M
- Manenti Er
- Manga P.
- Mangili Oc
- Manning Mb
- Manoj A
- Marar Ie
- Margoczy R
- Markovic Tp
- Marshall A
- Marten I
- Martens Fm
- Martin S
- Martinez Deben F
- Martinez Via L
- Martinez Lm
- Martinez Rf
- Martinka E
- Martorell Mateu E
- Martyin T
- Masana L
- Masiukiewicz U.
- Maskova P
- Masri Be
- Maus O
- Maw K
- Maximov Dm
- Maxwell Tg
- May O
- Mayfield Rk
- Maynard Km
- Mcadam B
- Mccartney Mj
- Mccormack T
- Mccullough L
- Mccullough Pa
- Mcgarvey Jf
- Mcgrew F
- Mckaig G
- Mckenzie Me
- Mclean B
- Mcmurray J
- McNally-Dufort C
- Mcnamara R
- Mcneil Dl
- Mcpherson C
- Mcpherson Tp
- Mediavilla Garcia Jd
- Medrano Martinez V
- Mego Dm
- Mehta Pm
- Mellbin L
- Mellbin L
- Mello Yg
- Melucci Mb
- Mendez Bucio A
- Mendoza Ja
- Michalaros Yl
- Micik J
- Miekus P
- Mierzejewski L
- Mikusova T
- Millar-Corte Gd
- Miller Ab
- Miller Ap
- Miller M.
- Minescu B
- Miranda Aa
- Mirek-Bryniarska E
- Miserez Ar
- Missault L
- Missault Lh
- Mistodie Cv
- Moccetti T
- Mociran M
- Molin Cj
- Molina Ca
- Mollerus Me
- Molto-Jorda Jm
- Monhart Z
- Montalescot G
- Montana O
- Montecinos H
- Montenegro Ee
- Montero M
- Montgomery B
- Mooe T
- Moon E
- Mootoo Ki
- Mora A
- Morales Portillo C
- Morales-Villegas E
- Moran G
- Morcos Nc
- Moriarty A
- Moriarty Pm
- Morocco T
- Morocutti G
- Morosanu M
- Morris Fh
- Morytko Ja
- Mosenzon O
- Mosseri M
- Mosterd A.
- Motylev I
- Mridha K
- Mudra H
- Mukherjee A
- Mulder H
- Mulleners T
- Muller C
- Multani P
- Muniz Grijalvo O
- Munoz Cf
- Munoz F
- Munteanu M
- Murcia A
- Murin J.
- Musungaie Db
- Myhill T
- Nadkarni S
- Nadra Ij
- Nagy A
- Nagy K
- Nagy L
- Nair Dr
- Nakandakare Er
- Nanchen D
- Nanji A
- Napoli Mc
- Narayan P
- Narejos S
- Nascimento Cv
- Nash Ml
- Nashed An
- Naudts I
- Neaton J
- Necki M
- Nedoshivin A
- Negrisanu Gd
- Nerg O
- Neuenschwander Fc
- Nguyen T
- Nicol Pr
- Nicolau J. C.
- Nielesen T
- Nielsen Wb
- Nierop Pr
- Nijmeijer R
- Nikolaev Ky
- Nisnisan Jm
- Nissen S.
- Nissen T
- Nixon Wa
- Noble S
- Nociar J
- Northroff J
- Norwood Pc
- Nseir Wb
- Nuriulu Escobar Pl
- Nye R
- Ochala A
- Odekirk Ll
- Okopien B
- Oleynikov V
- Olivares C
- Ong St
- Onrat E
- Opalinska E
- Orkwiszewska-Nalewajko A
- Oroszlan T
- Ostrowski J
- Ovalle F
- Owen Jg
- Ozcan T
- O’Dea Dj
- O’Mahoney M
- O’Neill B
- O’Steen Mb
- Pacheco Tr
- Paillard F
- Pak R
- Palchick Ba
- Palomaki A
- Panchenko E
- Pandey S
- Pantaleoni M
- Papp A
- Paraboschi Cf
- Paragh G
- Pasechnik E
- Pasqualini L
- Pasquini Ja
- Pasternak Da
- Pastrnakova E
- Patel Am
- Patle R
- Peart Bc
- Pegge N
- Pei D
- Pelaez Sv
- Pella D
- Pence D
- Peniston Jh
- Pereira Es
- Perez Martinez P
- Perez Paredes M
- Perez Ja
- Perings C
- Perlman Rl
- Perloff De
- Persson Be
- Pesant Y
- Peterfai E
- Peters Ss
- Peterson Sr
- Petit C
- Petrella J
- Pfuetzner A
- Pham Dn
- Piazza G
- Piepiorka M
- Pierpoint Be
- Pijanowski Z
- Pincetti C
- Pinto Sala X
- Pinto D
- Piovaccari G
- Pirro M
- Piskorz-Wapinska J
- Plaza Perez I
- Plazas Ja
- Pliamm L
- Plowchalk D
- Pluto Tm
- Pock J
- Pohlmeier L
- Polanczyk Ca
- Ponikowski P.
- Pons Amate Jm
- Pop Cf
- Popa Ar
- Popescu A
- Popescu M
- Popescu Ml
- Popov D
- Popova Vb
- Popoviciu Ms
- Porcu M
- Post Jc
- Potthoff S
- Pouzar Je
- Powell C
- Prasada S
- Precoma Db
- Pretorius Ce
- Pretorius Mm
- Price D
- Pride Y
- Probst V
- Proepper F
- Proietto J
- Promisloff Sd
- Pryke Jr
- Przekwas-Jaruchowska M
- Pudi Kk
- Puhakka M
- Purdy Da
- Purnell Pw
- Quyyumi Aa
- Rabahi F
- Radin Dm
- Radoi M
- Rai A
- Ramos Hr
- Ramos Mj
- Ramos Sa
- Ramos-Lopez Ga
- Ramstad Ds
- Randall Wj
- Randhawa Pm
- Range G
- Ranjith N
- Raoof Tj
- Raslova K
- Rasmanis G
- Rasmussen Tk
- Rech Rl
- Reddy Rd
- Redifer P
- Reed R
- Reedy Ma
- Reiber I
- Reis G
- Remmen Jj
- Rendell Ms
- Rensing Bj
- Resende Es
- Reshetko O
- Resk Jh
- Revkin J.
- Reyes Rg
- Reyna Ls
- Reynolds Rd
- Rhee My
- Rhudy Jm
- Rice S
- Rickers H
- Rico-Carrillo Ae
- Rictor Kw
- Ridker P. M.
- Riesenberg Ra
- Rigolosi R
- Rihani R
- Riksen Np
- Rim Sj
- Rinke A
- Riojas Charles Cm
- Ripoll Vera Tv
- Risser Ja
- Ritt Le
- Robertson Dg
- Robinson Jg
- Robinson Mf
- Robles Iniesta A
- Rocco Mb
- Rodriguez Ij
- Rodriguez Wr
- Rodriguez-Briones I
- Roman G
- Roman O
- Romer Tj
- Romero Hinojosa Ja
- Roncon L
- Ronner E
- Roos Js
- Roosen J
- Roquer Gonzalez J
- Rosenfeld Jc
- Rosenstock J
- Roskova E
- Ross S
- Rossi Pr
- Roubille F
- Roux Sm
- Rozpondek P
- Rubenfire M
- Ruiz La
- Ruiz-R L
- Ruoff Ge
- Rusculleda Mm
- Rusicka T
- Russo La
- Saad Ja
- Sachson Ra
- Sack G
- Saeed S
- Sahin T
- Sahul Zh
- Saini S
- Sala J
- Salacata A
- Salbach P
- Saldeen-Nilehn K
- Salter Tj
- Salvioni A
- Samoylova Yg
- Sanchez Alvarez J
- Sanchez Mijangos Jh
- Sanchez Ml
- Sandberg Jh
- Sansing Lh
- Santos R. D.
- Saporito Wf
- Saraiva Jf
- Sarens T
- Sari R
- Saryusz-Wolska M
- Sasson S
- Sathyapalan T
- Sattler C
- Saunders Kk
- Savin V
- Savolainen M
- Savolainen M
- Savonitto S
- Savonitto S
- Saxena S
- Schaap J
- Schade R
- Schaefer A
- Schaufele T
- Scheen A
- Schiele F
- Schiele Fn
- Schifferdecker B
- Schindler J
- Schlager D
- Schmedtje JF Jr
- Schmidberg J
- Schmidt E
- Schmidt U
- Schoell I
- Scholz G
- Schoofs Mw
- Schoors Df
- Schou M
- Schreuder T
- Schroe Hh
- Schuchard Tn
- Schumacher Dr
- Schwartz P. F.
- Schwartz W
- Schwimmbeck P
- Scott Bp
- Scott Dl
- Scott Rs
- Searles G
- Seaton Bl
- Seep Mk
- Segall N
- Segura T
- Seidman B
- Sensebrenner Jw
- Serje J
- Sesti G
- Sganzerla P
- Shah Sa
- Shalaev Sv
- Shammas N
- Shangina Oa
- Shapovalova J
- Sharir T
- Sharma R
- Sharma S
- Shayani Ss
- Sheahan D
- Shear C. L.
- Shechter M
- Shilkina Np
- Shimon I
- Shivaswamy V
- Shogenov Zs
- Shoukfeh M
- Shultz Jh
- Shutemova E
- Shvarts Y
- Sia Sm
- Sibon I
- Sidor M
- Sigal H
- Sillesen H
- Silva Rp
- Silverman Ie
- Simanenkov Vi
- Simon J
- Singal Dk
- Singh B
- Singh S
- Sitterli-Natea Cn
- Skaggs J
- Skripova D
- Smith P
- Smith Sk
- Smith Wb
- Sobolewska J
- Sobrino-Martinez J
- Sogorb Garri F
- Solar M
- Soler Jm
- Solodky A
- Solonev O
- Somogyi A
- Soosova I
- Soran H.
- Soroka E
- Sosa-Padilla Ma
- Soto Gonzalez A
- Soto Jr
- Sotolongo R
- Sotolongo Rp
- Soufflet V
- Sparks J
- Spence Jd
- Srimahachota S
- Sritara P
- Sritara P
- Srivastava S
- St-Amour E
- Staab Pk
- Stamps Hb
- Stawowy P
- Steffensen R
- Steinberg Aa
- Steinhoff Jp
- Stellbrink C
- Sternieri Mv
- Stevlik J
- Stich Ma
- Stobschinski Ca
- Stoessel J
- Stoller Sr
- Strader Jr
- Strain Je
- Strand J
- Strandberg A
- Stranks Sn
- Stratmann M
- Strbova J
- Stringam So
- Strobl Dj
- Strzinek Ra
- Stuckey T
- Styczkiewicz M
- Suarez Garcia S
- Suarez-Fernandez C
- Suarez-Sarmiento A
- Sullivan B
- Sullivan D
- Sultan S
- Sumbal J
- Suomi J
- Supronik J
- Suryanarayana Pg
- Sutton Jc
- Swart Hp
- Sweeney K
- Sydo T
- Sykulski R
- Szilagyi I
- Taeschner H
- Tahirkheli Nk
- Tahk Sj
- Takhar A
- Talano Jv
- Tami Lf
- Tan Ae
- Tanne D
- Tarasenko L
- Tarasov N
- Tardif
- Tase A
- Tatlisumak T
- Taurio J
- Taverna Llaurado E
- Tayoum H
- Teitelbaum I
- Tellier G
- Teltser M
- Tengmark Bo
- Ternouth If
- Terns Riera M
- Terrelonge Ae
- The Sh
- Thoeng J
- Thom S
- Thompson P
- Thomsen Kk
- Thouvenot E
- Ti Z
- Tichelaar P
- Timonen M
- Tinahones Madueno Fj
- Tivadar S
- Tofe Povedano S
- Toldy-Schedel E
- Tolkacheva V
- Torre Amione G
- Tortensson I
- Toth K
- Toth L
- Townsend Jc
- Traboulssi Ma
- Treasure Cb
- Trebacz J
- Trenk D
- Triana Eh
- Trimarco B
- Trippett Jm
- Troquay Rp
- Truban J
- Tsai Wc
- Tsalihin D
- Tumelero R
- Tunon J
- Turner Ta
- Turner W
- Twum-Barima Dy
- Tökgozoğlu L
- Ueng Kc
- Uhliar R
- Ulla Mr
- Underberg Ja
- Updegrove Jd
- Uresin Ay
- Urhammer S
- Urina M
- Urina-Triana Ma
- Uusinarkaus Kt
- Vaca Ce
- Vahed Ya
- Valdez Lopez Hg
- Valtonen M
- Van Alem Ap
- van Beek E
- van Daele Me
- van de Borne P
- van de Wal Rm
- van de Wetering Ml
- van de Wiel A
- van der Meer P
- van der Walt E
- van der Zwaan Ct
- Van Gaal W
- van Hal Jm
- Van het Hof-Wiersma Jj
- van Kempen Ww
- Van Koningsbruggen P
- van Landegem P
- van Leendert Rj
- van Nieuwenhuizen E
- van Rossum P
- van Royen N
- van Zyl Lj
- Vannatta B
- Vanttinen E
- Varleta P
- Vazan A
- Vazquez-Tanus Jb
- Veenendaal A
- Vejar M
- Venereo Jm
- Venter Dj
- Verdeza C
- Vertes A
- Vervoort G
- Verwerft J
- Vesely J
- Vico Ml
- Viergever Ep
- Viklund J
- Vila Belmonte A
- Villaman-Bencosme Y
- Vinanska D
- Vincent J.
- Vincent S
- Vinyoles Bargallo E
- Violante Ortiz R
- Vishlitzky V
- Vishneva E
- Visser Rp
- Visseren F
- Vivekananthan K
- Vizel S
- Vlach Jj
- Vodnansky P
- Voehringer Hf
- Vogel Dr
- Vohnout B
- Vojacek J
- Volkova A
- Voller H
- von Engelhardt Cb
- von Hodenberg Ef
- Vora Kn
- Vora Sk
- Voros P
- Vrablik M.
- Vrkoc J
- Vukotic G
- Wadud K
- Wainstein J
- Wakefield Ph
- Wakeling J
- Walczak M
- Walczewska J
- Walukiewica P
- Wang D
- Wang E
- Wang G
- Wang Y
- Wasserburger B
- Waxler Ar
- Wayne Jd
- Weber D
- Weber K
- Wegner J
- Wei C
- Weigmann I
- Weinstein Dl
- Weiss R
- Welker Ja
- Welty F
- Wenetz Lm
- Wermuth S
- Wesson T
- West Sh
- Westerndorp I
- Wetzel T
- White H.
- Whitlock L
- Whitney Rt
- Wiggers H
- William M
- Williams Dg
- Williams M
- Willis Jg
- Willits Vl
- Winkelmann B
- Witt N
- Wittmann I
- Woehrle J
- Worner Diz F
- Wozniak I
- Wright R. S.
- Wronska D
- Wuerzner G
- Wychota K
- Xu P
- Xue L
- Yakusevich Vv
- Yang P
- Yang X
- Yao Lc
- Yared Z
- Yarows Sa
- Yigit Z
- Yoon J
- Yunis C.
- Zadra R
- Zaidman Cj
- Zamorano Gomez Jl
- Zannad F
- Zarandon Rb
- Zarich Sw
- Zateyshchikov D
- Zavaro Sh
- Zebrack Js
- Zeig S
- Zemek S
- Zemour G
- Zeng X
- Zeno Ml
- Zhang L
- Zhang X
- Zhang Y
- Zhao Y
- Zhou C
- Zhou Y
- Zhu Y
- Zidkova E
- Zieba B
- Zilahi Z
- Zoet-Nugteren Sk
- Zrazhevskiy K
- Zubek V
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin- kexin type 9 (PCSK9) and reduces levels of low-density lipoprotein (LDL) cholesterol. We sought to evaluate the efficacy of bococizumab in patients at high cardiovascular risk. METHODS In two parallel, multinational trials with different entry criteria for LDL cholesterol levels, we randomly assigned the 27,438 patients in the combined trials to receive bococizumab (at a dose of 150 mg) subcutaneously every 2 weeks or placebo. The primary end point was nonfatal myocardial infarction, nonfatal stroke, hospitalization for unstable angina requiring urgent revascularization, or cardiovascular death; 93% of the patients were receiving statin therapy at baseline. The trials were stopped early after the sponsor elected to discontinue the development of bococizumab owing in part to the development of high rates of antidrug antibodies, as seen in data from other studies in the program. The median follow-up was 10 months. RESULTS At 14 weeks, patients in the combined trials had a mean change from baseline in LDL cholesterol levels of -56.0% in the bococizumab group and +2.9% in the placebo group, for a between-group difference of -59.0 percentage points (P<0.001) and a median reduction from baseline of 64.2% (P<0.001). In the lower-risk, shorter-duration trial (in which the patients had a baseline LDL cholesterol level of ≥70 mg per deciliter [1.8 mmol per liter] and the median follow-up was 7 months), major cardiovascular events occurred in 173 patients each in the bococizumab group and the placebo group (hazard ratio, 0.99; 95% confidence interval [CI], 0.80 to 1.22; P = 0.94). In the higher-risk, longer-duration trial (in which the patients had a baseline LDL cholesterol level of ≥100 mg per deciliter [2.6 mmol per liter] and the median follow-up was 12 months), major cardiovascular events occurred in 179 and 224 patients, respectively (hazard ratio, 0.79; 95% CI, 0.65 to 0.97; P = 0.02). The hazard ratio for the primary end point in the combined trials was 0.88 (95% CI, 0.76 to 1.02; P = 0.08). Injection-site reactions were more common in the bococizumab group than in the placebo group (10.4% vs. 1.3%, P<0.001). CONCLUSIONS In two randomized trials comparing the PCSK9 inhibitor bococizumab with placebo, bococizumab had no benefit with respect to major adverse cardiovascular events in the trial involving lower-risk patients but did have a significant benefit in the trial involving higher-risk patients
Application of27Al NMR techniques to structure determination in solids
- Author
- A. Abragam
- A. Ibarra
- A. Llor
- A. Rettel
- A. Samoson
- A. Samoson
- A. Samoson
- A. Samoson
- A. Samoson
- A. Samoson
- A. Samoson
- A. Yasumori
- A.-P.S. Mandair
- A.-P.S. Mandair
- A.C. Kunwar
- A.C. Kunwar
- A.D. Irwin
- A.J. Vega
- A.P.M. Kentgens
- B. Derighetti
- B. Sulikowski
- B.A. Goodman
- B.C. Bunker
- B.C. Gerstein
- B.H.W.S. Jong De
- B.J. Wood
- B.L. Phillips
- B.L. Phillips
- B.L. Phillips
- B.L. Sherriff
- C.A. Fyfe
- C.A. Fyfe
- C.A. Fyfe
- C.I. Merzbacher
- C.S. Blackwell
- C.S. Blackwell
- C.S. John
- D. Brinkmann
- D. Fenzke
- D. Freude
- D. Freude
- D. Freude
- D. Freude
- D. Goldfarb
- D. Hasha
- D. Lee
- D. Massiot
- D. Massiot
- D. Massiot
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D. Muller
- D.E. Woessner
- D.E. Woessner
- D.L. Hamilton
- D.R. Corbin
- D.R. Corbin
- D.T.B. Tennakoon
- D.T.B. Tennakoon
- E. Brun
- E. Brun
- E. Brun
- E. Fukushima
- E. Hallas
- E. Hallas
- E. Hallas
- E. Jahn
- E. Jahn
- E. Jahn
- E. Kundla
- E. Kundla
- E. Lippmaa
- E. Ohtani
- E.G. Derouane
- E.R. Andrew
- E.R. Andrew
- E.R. Andrew
- F. Euler
- F. Lefebvre
- F. Taulelle
- F.M.M. Geurts
- G. Engelhardt
- G. Engelhardt
- G. Engelhardt
- G. Ganapathy
- G.J. Ray
- G.K. Stauss
- G.L. Marshall
- G.M. Volkoff
- H. Hamdan
- H. Kodama
- H.D. Morris
- H.D. Morris
- H.E. Petch
- H.E.N. Petch
- H.J. Behrens
- H.J. Jakobsen
- H.J. Jakobsen
- H.J. Jakobsen
- H.S. Jacobsen
- I. Farnan
- I. Watanabe
- I.P. Appleyard
- I.W.M. Brown
- I.W.M. Brown
- J. Bohm
- J. Covino
- J. Haase
- J. Haase
- J. Klinowski
- J. Klinowski
- J. Klinowski
- J. Klinowski
- J. Klinowski
- J. Klinowski
- J. Klinowski
- J. Rocha
- J. Rocha
- J. Sanz
- J. Sanz
- J. Sanz
- J. Sanz
- J. Skibsted
- J. Skibsted
- J.B. Fletcher
- J.C. Pouxviel
- J.E. Shelby
- J.E. Shelby
- J.F. Lambert
- J.F. Stebbins
- J.F. Stebbins
- J.G. Thompson
- J.H. Hockenberry
- J.J. Fitzgerald
- J.J. Fitzgerald
- J.J. Fitzgerald
- J.M. Cruz
- J.M. Thomas
- J.P. Amoreux
- J.P. Amoureux
- J.S. Frye
- J.S. Hartman
- K. Akimoto
- K. Wada
- K. Wada
- K.A. Muller
- K.C. Brog
- K.F.M.G.J. Scholle
- K.J.D. MacKenzie
- K.J.D. MacKenzie
- K.J.D. Mackenzie
- K.R. Carduner
- K.R. Carduner
- K.T. Mueller
- L. Kellberg
- L. Maistraiu
- L.A. Groat
- L.B. Alemany
- L.B. Alemany
- L.B. Alemany
- L.C. Brown
- L.H. Merwin
- L.S. Vorotilova
- M. E. Smith
- M. Hahnert
- M. McMillan
- M. Raymond
- M.A. Wilson
- M.A. Wilson
- M.A. Wilson
- M.E. Smith
- M.H. Cohen
- M.J. Hey
- M.M. Maricq
- M.W. Anderson
- N.C. Nielsen
- N.C.M. Alma
- N.D. Butler
- N.V. Tapp
- O.H. Han
- O.P. Krivoruchko
- P. Massiani
- P. McMillan
- P. Nortier
- P.A. Casabella
- P.C. Schmidt
- P.F. Barron
- P.J. Barrie
- P.J. Barrie
- P.J. Chu
- P.J. Grobet
- P.J. Grobet
- P.P. Man
- P.P. Man
- P.P. Man
- P.Y. Efitsenko
- R. Challoner
- R. Couty
- R. Couty
- R. Couty
- R. Dupree
- R. Dupree
- R. Dupree
- R. Dupree
- R. Dupree
- R. Dupree
- R. Dupree
- R. Dupree
- R. Jelinek
- R. Oestrike
- R. Oestrike
- R.A. Kinsey
- R.A. Wind
- R.C.T. Slade
- R.C.T. Slade
- R.E.J. Sears
- R.G. Eades
- R.H. Meinhold
- R.J. Kirkpatrick
- R.J. Kirkpatrick
- R.J. Kirkpatrick
- R.K. Brow
- R.K. Sato
- R.K. Sato
- R.K. Sato
- R.L. Frost
- R.M. Pearson
- R.M. Sternheimer
- R.M. Sternheimer
- R.V. Pound
- S. Ganapathy
- S. Ghose
- S. Ghose
- S. Hayashi
- S. Komarneni
- S. Komarneni
- S. Komarneni
- S. Komarneni
- S. Komarneni
- S. Komarneni
- S. Komarneni
- S. Rubini
- S.C. Kohn
- S.C. Kohn
- S.F. Dec
- S.F. Dec
- S.F. Dec
- S.H. Risbud
- S.L. Hietato
- S.S. Hafner
- S.S. Hafner
- S.S. Hafner
- T. Bastow
- T. Luong
- T. Nishio
- T. Tsang
- T. Tsang
- T.P.P. Cheung
- U. Haeberlen
- U. Selvaraj
- V. Bosacek
- V. Langer
- V.H. Schmidt
- V.M. Mastikhin
- W. Gessner
- W. Gessner
- W.A. Dollase
- W.F. Bleam
- W.F. Bleam
- W.H. Yang
- W.H.A. Yang
- W.H.A. Yang
- W.L. Olsen
- Y. Wu
- Y. Wu
- Z Luz
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study