A New Observational Upper Limit to the Low Redshift Ionizing Background Radiation

We report a new Fabry-Perot search for Halpha emission from the intergalactic cloud HI 1225+01 in an attempt to measure the low redshift ionizing background radiation. We set a new 2 sigma upper limit on Halpha emission of 8 mR (5 x 10^{-20} ergs cm^{-2} s^{-1} arcsec^{-2}). Conversion of this limit to limits on the strength of the ionizing background requires knowledge of the ratio of the projected to total surface area of this cloud, which is uncertain. We discuss the plausible range of this ratio, and within this range find that the strength of the ionizing backround is in the lower range of, but consistent with, previous observational and theoretical estimates.Comment: 46 pages including 9 figures (7 ps, 2 gif

Player chronotype does not affect shooting accuracy at different times of the day in a professional, male basketball team: a pilot study

Athlete chronotype has been documented to underpin diurnal variations in skill execution across various team sports. However, no research has explored the effects of athlete chronotype on basketball-specific skills at different times of the day. Therefore, the aim of this study was to explore diurnal variations in basketball shooting accuracy according to chronotype. Professional, male basketball players (n = 13) completed a Morningness- Eveningness Questionnaire and were categorised into chronotypes using a tertile split technique (morning-types: n = 4; neither-types: n = 4; evening-types: n = 5). Players completed separate trials of a shooting accuracy test in the morning (08:00-09:30h) and afternoon (15:00-16:30h) with each trial consisting of 20 shots attempted from four court locations at either two- or three-point distances and one-shot location from the free-throw line (100 shots in total). Each shot attempt was scored using a 0-3-point scale with higher scores awarded to more accurate shots. Non-significant (p >0.05) differences in shooting scores were evident between morning and afternoon trials for each chronotype group, with small-large effects in shooting scores favouring the morning across groups. Moreover, non-significant (p >0.05) differences in shooting scores were apparent between chronotype groups in the morning (small-large effects) and afternoon (moderate-large effects). Shooting accuracy appears to remain consistent across morning and afternoon performances irrespective of player chronotype in a professional basketball team, suggesting coaches may not need to schedule training sessions involving shooting tasks at specific times of the day to optimise shooting accuracy in players

Commercial chicken breeds exhibit highly divergent patterns of linkage disequilibrium

The analysis of linkage disequilibrium (LD) underpins the development of effective genotyping technologies, trait mapping and understanding of biological mechanisms such as those driving recombination and the impact of selection. We apply the Malécot-Morton model of LD to create additive LD maps that describe the high-resolution LD landscape of commercial chickens. We investigated LD in chickens (Gallus gallus) at the highest resolution to date for broiler, white egg and brown egg layer commercial lines. There is minimal concordance between breeds of fine-scale LD patterns (correlation coefficient <0.21), and even between discrete broiler lines. Regions of LD breakdown, which may align with recombination hot spots, are enriched near CpG islands and transcription start sites (P<2.2 × 10?16), consistent with recent evidence described in finches, but concordance in hot spot locations between commercial breeds is only marginally greater than random. As in other birds, functional elements in the chicken genome are associated with recombination but, unlike evidence from other bird species, the LD landscape is not stable in the populations studied. The development of optimal genotyping panels for genome-led selection programmes will depend on careful analysis of the LD structure of each line of interest. Further study is required to fully elucidate the mechanisms underlying highly divergent LD patterns found in commercial chickens

The Palestinian primary ciliary dyskinesia population: first results of the diagnostic, and genetic spectrum

BACKGROUND: Diagnostic testing for primary ciliary dyskinesia (PCD) started in 2013 in Palestine. We aimed to describe the diagnostic, genetic and clinical spectrum of the Palestinian PCD population. METHODS: Individuals with symptoms suggestive of PCD were opportunistically considered for diagnostic testing: nasal nitric oxide (nNO) measurement, transmission electron microscopy (TEM) and/or PCD genetic panel or whole-exome testing. Clinical characteristics of those with a positive diagnosis were collected close to testing including forced expiratory volume in 1 s (FEV1) Global Lung Index z-scores and body mass index z-scores. RESULTS: 68 individuals had a definite positive PCD diagnosis, 31 confirmed by genetic and TEM results, 23 by TEM results alone, and 14 by genetic variants alone. 45 individuals from 40 families had 17 clinically actionable variants and four had variants of unknown significance in 14 PCD genes. CCDC39, DNAH11 and DNAAF11 were the most commonly mutated genes. 100% of variants were homozygous. Patients had a median age of 10.0 years at diagnosis, were highly consanguineous (93%) and 100% were of Arabic descent. Clinical features included persistent wet cough (99%), neonatal respiratory distress (84%) and situs inversus (43%). Lung function at diagnosis was already impaired (FEV1 z-score median −1.90 (−5.0–1.32)) and growth was mostly within the normal range (z-score mean −0.36 (−3.03–2.57). 19% individuals had finger clubbing. CONCLUSIONS: Despite limited local resources in Palestine, detailed geno- and phenotyping forms the basis of one of the largest national PCD populations globally. There was notable familial homozygosity within the context of significant population heterogeneity

Dielectronic recombination data for dynamic finite-density plasmas I. Goals and methodology

A programme is outlined for the assembly of a comprehensive dielectronic recombination database within the generalized collisional--radiative (GCR) framework. It is valid for modelling ions of elements in dynamic finite-density plasmas such as occur in transient astrophysical plasmas such as solar flares and in the divertors and high transport regions of magnetic fusion devices. The resolution and precision of the data are tuned to spectral analysis and so are sufficient for prediction of the dielectronic recombination contributions to individual spectral line emissivities. The fundamental data are structured according to the format prescriptions of the Atomic Data and Analysis Structure (ADAS) and the production of relevant GCR derived data for application is described and implemented following ADAS. The requirements on the dielectronic recombination database are reviewed and the new data are placed in context and evaluated with respect to older and more approximate treatments. Illustrative results validate the new high-resolution zero-density dielectronic recombination data in comparison with measurements made in heavy-ion storage rings utilizing an electron cooler. We also exemplify the role of the dielectronic data on GCR coefficient behaviour for some representative light and medium weight elements.Comment: 14 Pages, 9 Figures. Submitted to Astronomy & Astrophysics April 12, 200

Late Spectral Evolution of SN 1987A: I. Temperature and Ionization

The temperature and ionization of SN 1987A is modeled between 200 and 2000 days in its nebular phase, using a time-dependent model. We include all important elements, as well as the primary composition zones in the supernova. The energy input is provided by radioactive decay of Co-56, Co-57, and Ti-44. The thermalization of the resulting gamma-rays and positrons is calculated by solving the Spencer-Fano equation. Both the ionization and the individual level populations are calculated time-dependently. Adiabatic cooling is included in the energy equation. Charge transfer is important for determining the ionization and is included with available and estimated rates. Full, multilevel atoms are used for the observationally important ions. As input models to the calculations we use explosion models for SN 1987A calculated by Woosley et al and Nomoto et al. The most important result in this paper refers to the evolution of the temperature and ionization of the various abundance zones. The metal-rich core undergoes a thermal instability, often referred to as the IR-catastrophe, at 600 - 1000 days. The hydrogen-rich zones evolve adiabatically after 500 - 800 days, while in the helium region both adiabatic cooling and line cooling are of equal importance after ~1000 days. Freeze-out of the recombination is important in the hydrogen and helium zones. Concomitant with the IR-catastrophe, the bulk of the emission shifts from optical and near-IR lines to the mid- and far-IR. After the IR-catastrophe, the cooling is mainly due to far-IR lines and adiabatic expansion. Dust cooling is likely to be important in the zones where dust forms. We find that the dust condensation temperatures occur later than ~500 days in the oxygen-rich zones, and the most favorable zone for dust condensation is the iron core.Comment: 53 pages, including 10 figures; ApJ (Main Journal); scheduled for April 1, 1998, Vol. 49

Growth of the C4 dicot Flaveria bidentis: photosynthetic acclimation to low light through shifts in leaf anatomy and biochemistry

In C4 plants, acclimation to growth at low irradiance by means of anatomical and biochemical changes to leaf tissue is considered to be limited by the need for a close interaction and coordination between bundle sheath and mesophyll cells. Here differences in relative growth rate (RGR), gas exchange, carbon isotope discrimination, photosynthetic enzyme activity, and leaf anatomy in the C4 dicot Flaveria bidentis grown at a low (LI; 150 μmol quanta m2 s−1) and medium (MI; 500 μmol quanta m2 s−1) irradiance and with a 12 h photoperiod over 36 d were examined. RGRs measured using a 3D non-destructive imaging technique were consistently higher in MI plants. Rates of CO2 assimilation per leaf area measured at 1500 μmmol quanta m2 s−1 were higher for MI than LI plants but did not differ on a mass basis. LI plants had lower Rubisco and phosphoenolpyruvate carboxylase activities and chlorophyll content on a leaf area basis. Bundle sheath leakiness of CO2 (ϕ) calculated from real-time carbon isotope discrimination was similar for MI and LI plants at high irradiance. ϕ increased at lower irradiances, but more so in MI plants, reflecting acclimation to low growth irradiance. Leaf thickness and vein density were greater in MI plants, and mesophyll surface area exposed to intercellular airspace (Sm) and bundle sheath surface area per unit leaf area (Sb) measured from leaf cross-sections were also both significantly greater in MI compared with LI leaves. Both mesophyll and bundle sheath conductance to CO2 diffusion were greater in MI compared with LI plants. Despite being a C4 species, F. bidentis is very plastic with respect to growth irradiance

Spatial analysis of air pollution and childhood asthma in Hamilton, Canada: comparing exposure methods in sensitive subgroups

<p>Abstract</p> <p>Background</p> <p>Variations in air pollution exposure within a community may be associated with asthma prevalence. However, studies conducted to date have produced inconsistent results, possibly due to errors in measurement of the exposures.</p> <p>Methods</p> <p>A standardized asthma survey was administered to children in grades one and eight in Hamilton, Canada, in 1994–95 (N ~1467). Exposure to air pollution was estimated in four ways: (1) distance from roadways; (2) interpolated surfaces for ozone, sulfur dioxide, particulate matter and nitrous oxides from seven to nine governmental monitoring stations; (3) a kriged nitrogen dioxide (NO₂) surface based on a network of 100 passive NO₂monitors; and (4) a land use regression (LUR) model derived from the same monitoring network. Logistic regressions were used to test associations between asthma and air pollution, controlling for variables including neighbourhood income, dwelling value, state of housing, a deprivation index and smoking.</p> <p>Results</p> <p>There were no significant associations between any of the exposure estimates and asthma in the whole population, but large effects were detected the subgroup of children without hayfever (predominately in girls). The most robust effects were observed for the association of asthma without hayfever and NO₂LUR OR = 1.86 (95%CI, 1.59–2.16) in all girls and OR = 2.98 (95%CI, 0.98–9.06) for older girls, over an interquartile range increase and controlling for confounders.</p> <p>Conclusion</p> <p>Our findings indicate that traffic-related pollutants, such as NO₂, are associated with asthma without overt evidence of other atopic disorders among female children living in a medium-sized Canadian city. The effects were sensitive to the method of exposure estimation. More refined exposure models produced the most robust associations.</p

How do parents manage irritability, challenging behavior, non-compliance and anxiety in children with Autism Spectrum Disorders? A meta-synthesis

Although there is increasing research interest in the parenting of children with ASD, at present, little is known about everyday strategies used to manage problem behaviour. We conducted a meta-synthesis to explore what strategies parents use to manage irritability, non-compliance, challenging behaviour and anxiety in their children with ASD. Approaches included: (1) accommodating the child; (2) modifying the environment; (3) providing structure, routine and occupation; (4) supervision and monitoring; (5) managing non-compliance with everyday tasks; (6) responding to problem behaviour; (7) managing distress; (8) maintaining safety and (9) analysing and planning. Results suggest complex parenting demands in children with ASD and problem behaviour. Findings will inform the development of a new measure to quantify parenting strategies relevant to ASD