31 research outputs found

    Language policy and orthographic harmonization across linguistic, ethnic and national boundaries in Southern Africa

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    Drawing on online and daily newspapers, speakers' language and writing practices, official government documents and prescribed spelling systems in Southern Africa, the paper explores the challenges and possibilities of orthographic reforms allowing for mobility across language clusters, ethnicity, regional and national borders. I argue that this entails a different theorisation of language, and for orthographies that account for the translocations and diasporic nature of late modern African identities and lifestyles. I suggest an ideological shift from prescriptivism to practice-orientated approaches to harmonisation in which orthographies are based on descriptions of observable writing practices in the mobile linguistic universe. The argument for orthographic reforms is counterbalanced with an expose on current language policies which appear designed for an increasing rare monoglot 'standard' speaker, who speaks only a 'tribal' language. The implications of the philosophical challenges this poses for linguists, language planners and policy makers are thereafter discussed.IS

    A novel community driven software for functional enrichment analysis of extracellular vesicles data.

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    Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines

    Regional price transmission in Southern African maize markets

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    In light of the importance of maize as a staple crop in Southern Africa, as well as its prioritisation from a policy perspective, this study evaluates the extent of price transmission between selected maize markets in the region. It employs secondary data of weekly white maize prices in seven markets in the region to quantify the long and short run price relationships between relevant markets based on geographic proximity and expected trade patterns. While several authors have noted the isolation of white maize markets in Southern Africa from the global market, this study finds evidence of co-integration between multiple maize markets within the Southern African region. By implication, policy decisions affecting prices in any single country will influence price levels in multiple surrounding markets, impacting on both producer and consumer welfare not only in the country of application but also in the region as a whole

    Evaluating price volatility and the role of trade in Eastern and Southern African maize markets

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    Food price volatility, particularly in key food staple markets, has been a long standing challenge in Sub-Saharan Africa, where prices are already some of the highest in the world. In many cases, governments have acted to curb volatility, though several researchers have shown that actions aimed at reducing volatility in the short run have often been counterproductive for long term aims of market led productivity growth that would be able to reduce high prices in the region. With increased intra-regional trade having been proposed as a solution to volatile prices in the region, this study finds that across a sample of 36 maize markets in Eastern and Southern Africa between 2008 and 2014, volatility is significantly lower in markets with higher trade volumes. Thus it postulates that policies aimed at increasing the efficiency and reducing the cost of intra-regional trade will be efficient in curbing volatility in the region, thus improving food security

    HIV Suppresses Cervical Neutrophil Infiltration in Women with Normal or Abnormal Pap Smears

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    Human immunodeficiency virus (HIV) infection of CD4+ T cells results in a weakened immune system due to decreased white blood cells, particularly multi-lobed neutrophils (neutropenia) and other granulocytes.1 The purpose of this study was to determine whether a correlation exists between HPV/HIV status and presence of neutrophils. To test this, we used a computer software program (QuPath) to analyze neutrophil infiltration seen in pap smears of both HIV+ and HIV- patients from samples collected in Tanzania from three different sites: Bagamoyo, Chalinze, and Dar es Salaam. The software was used to quantify neutrophils per image based on the size and shape of the nuclei. For each sample, three slide images were taken and the average neutrophil count was determined through QuPath and compared to data about sample HIV and HPV status from a previous study. Results showed that HIV+ patients had significantly lower neutrophil counts, regardless of HPV type and cytology grade based on the Bethesda system. Therefore, we concluded that cervical neutrophil infiltration is suppressed in HIV+ samples for both normal and abnormal pap smears. 1. Shi, X. et al. Neutropenia during HIV infection: adverse consequences and remedies. Int Rev Immunol 33, 511-536 (2014)
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