Machine Learning: The Backbone of Intelligent Trade Credit-Based Systems

Technology has turned into a significant differentiator in the money and traditional recordkeeping systems for the financial industry. To depict two customers as potential investors, it is mandatory to give the complex innovation that they anticipate and urge to purchase. In any case, it is difficult to keep on top of and be a specialist in each of the new advancements that are accessible. By reappropriating IT administrations, monetary administrations firms can acquire prompt admittance to the most recent ability and direction. Financial systems, along with machine learning (ML) algorithms, are vital for critical concerns like secure financial transactions and automated trading. These are the key to the provision of financial decisions for investors and stakeholders for the firms which are working with the trade credit (TC) approach, in Small and Medium Industries (SMEs). Huge and very sensitive data is processed in a limited time. The trade credit is a reason for more financial gains. The impact of TC with predictive machine learning algorithms is the reason why intelligent and safe revenue generation is the main target of the proposed study. That is, the combination of financial data and technology (FinTech) domains is a potential reason for sales growth and ultimately more profit.publishedVersio

Evaluation of different sorghum (Sorghum bicolor L. moench) varieties for grain yield and related characteristics

Abstract Eight sorghum genotypes were evaluated for grain and other associated traits at Maize and Millets Research Institute, Yousafwala, Sahiwal, Punjab, Pakistan in 2011. The results revealed that sorghum varieties differed significantly for grain yield, fodder yield, plant height and days to 50% flowering. Among the varieties, YSS-9, YSS-10 (Cream) and YSS-17 produced higher grain yield (3433, 3167 and 3100 kg ha -1 , respectively) than other genotypes. Varieties YSS-9 and YSS-10 (Cream) produced higher fodder yield of 15833 and 12000 kg ha -1 , respectively. Sorghum variety YSS-10 (cream) took maximum days (86) to 50% flowering, while variety YSS-98 (control) took minimum 79 days to 50% flowering. Among the tested genotypes, YSS-9 produced higher grain yield as well as fodder yield (stay greener at maturity) than all other genotypes. It has a bold grain size of creamy color which has no tannin contents (anti nutritional factor) and strong root anchor system. So it is concluded that YSS-9 proved as a dual-purpose variety with reasonable grain and fodder yields

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Methods: We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124. Findings: Between July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98). Interpretation: We found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study

Purpose Delirium is a neuropsychiatric disorder delineated by an acute change in cognition, attention, and consciousness. It is common, particularly in older adults, but poorly recognised. Frailty is the accumulation of deficits conferring an increased risk of adverse outcomes. We set out to determine how severity of frailty, as measured using the CFS, affected delirium rates, and recognition in hospitalised older people in the United Kingdom. Methods Adults over 65 years were included in an observational multi-centre audit across UK hospitals, two prospective rounds, and one retrospective note review. Clinical Frailty Scale (CFS), delirium status, and 30-day outcomes were recorded. Results The overall prevalence of delirium was 16.3% (483). Patients with delirium were more frail than patients without delirium (median CFS 6 vs 4). The risk of delirium was greater with increasing frailty [OR 2.9 (1.8–4.6) in CFS 4 vs 1–3; OR 12.4 (6.2–24.5) in CFS 8 vs 1–3]. Higher CFS was associated with reduced recognition of delirium (OR of 0.7 (0.3–1.9) in CFS 4 compared to 0.2 (0.1–0.7) in CFS 8). These risks were both independent of age and dementia. Conclusion We have demonstrated an incremental increase in risk of delirium with increasing frailty. This has important clinical implications, suggesting that frailty may provide a more nuanced measure of vulnerability to delirium and poor outcomes. However, the most frail patients are least likely to have their delirium diagnosed and there is a significant lack of research into the underlying pathophysiology of both of these common geriatric syndromes

Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study

Purpose: Delirium is a neuropsychiatric disorder delineated by an acute change in cognition, attention, and consciousness. It is common, particularly in older adults, but poorly recognised. Frailty is the accumulation of deficits conferring an increased risk of adverse outcomes. We set out to determine how severity of frailty, as measured using the CFS, affected delirium rates, and recognition in hospitalised older people in the United Kingdom. Methods: Adults over 65 years were included in an observational multi-centre audit across UK hospitals, two prospective rounds, and one retrospective note review. Clinical Frailty Scale (CFS), delirium status, and 30-day outcomes were recorded. Results: The overall prevalence of delirium was 16.3% (483). Patients with delirium were more frail than patients without delirium (median CFS 6 vs 4). The risk of delirium was greater with increasing frailty [OR 2.9 (1.8–4.6) in CFS 4 vs 1–3; OR 12.4 (6.2–24.5) in CFS 8 vs 1–3]. Higher CFS was associated with reduced recognition of delirium (OR of 0.7 (0.3–1.9) in CFS 4 compared to 0.2 (0.1–0.7) in CFS 8). These risks were both independent of age and dementia. Conclusion: We have demonstrated an incremental increase in risk of delirium with increasing frailty. This has important clinical implications, suggesting that frailty may provide a more nuanced measure of vulnerability to delirium and poor outcomes. However, the most frail patients are least likely to have their delirium diagnosed and there is a significant lack of research into the underlying pathophysiology of both of these common geriatric syndromes

Frequency of External Ventricular Drain Related Infection

The management of brain tumors of the pediatric brain tumors may involve surgical option like craniotomy. This procedure can lead to the complications like cerebrospinal fluid (CSF) leakage which is difficult to manage. This study was an audit of craniotomy among pediatric brain tumor patients. Objective: To determine the frequency of CSF leak after craniotomy for paediatric brain tumor. Study Design: Descriptive case series. Setting: Department of Neurosurgery, Nishtar Hospital, Multan. Duration: 03 year 01/06/2010 to 30/06/2013. Methods: This study included 208 patients with pediatric brain tumors. All the patients had craniotomy done through supratentorial or infratentorial approach. The patients were followed up for occurrence of CSF leakage upto two weeks. Data was collected in a specially designed performa. Results: The mean age of the patients was 10.36 ± 4.97 years (range 6 months – 18 years). There were 44 (21.2%) female and 164 (79.8%) patients were male. Craniotomies through supratentorial and infratentorial approach were done in 176 (84.6%) and 32 (15.4%) patients, respectively. CSF leakage was observed among 28 (13.5%) patient. Conclusions: The CSF leakage rates after craniotomy in pediatric population having brain tumors are high. However, this rate is high among patients who undergo through infratentorial techniques as compared to supratentorial technique. Abbreviations: CSF = Cerebrospinal fluid. CNS = Central nervous system

Machine Learning: The Backbone of Intelligent Trade Credit-Based Systems

Technology has turned into a significant differentiator in the money and traditional recordkeeping systems for the financial industry. To depict two customers as potential investors, it is mandatory to give the complex innovation that they anticipate and urge to purchase. In any case, it is difficult to keep on top of and be a specialist in each of the new advancements that are accessible. By reappropriating IT administrations, monetary administrations firms can acquire prompt admittance to the most recent ability and direction. Financial systems, along with machine learning (ML) algorithms, are vital for critical concerns like secure financial transactions and automated trading. These are the key to the provision of financial decisions for investors and stakeholders for the firms which are working with the trade credit (TC) approach, in Small and Medium Industries (SMEs). Huge and very sensitive data is processed in a limited time. The trade credit is a reason for more financial gains. The impact of TC with predictive machine learning algorithms is the reason why intelligent and safe revenue generation is the main target of the proposed study. That is, the combination of financial data and technology (FinTech) domains is a potential reason for sales growth and ultimately more profit

Maximum sustainable yield estimation of shellfish fishery in Chinese marine waters by using surplus production modelling approach

1774-1781In this study, maximum sustainable yield (MSY) of shellfish fishery from Chinese marine waters is estimated through two stock assessment softwares i.e. ASPIC (a surplus production model incorporating covariates) and CEDA (catch and effort data analysis). The initial catch was approximately 90%; hence, the MSY was estimated with initial proportion (IP) of 0.9 in both softwares. In ASPIC for this IP value, estimated MSY and goodness of fit (R2) parameters for FM were observed as 336100 t and 0.857 while for LM their estimated values remained as 316600 t and 0.856, correspondingly. In CEDA for IP value 0.9, SM and PTM estimated same MSY 213957 t, 322791 t and 266213 t for all the three error assumptions. FM for log and log normal error assumptions estimated MSY as 249382 t and 338355 t and R2 = 0.756 and 0.786, respectively. However, gamma error assumption produced minimization failure (MF)

Molluscan fisheries in Pakistan: Trends in capture production, utilization and trade

929-935Overall, molluscan capture production has increased manifolds; however after 2000 there is decreasing trend in its production. There is no recorded data for its consumption in Pakistan. Trade values show that this commodity is mainly exported and there is negligible sporadic import in few years. Export and percentage contribution of molluscan fisheries in total seafood production is decreasing with the passage of time