Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach

<p>Abstract</p> <p>Background</p> <p>The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic from the perspective of the virus has not previously been traced.</p> <p>Results</p> <p>In the current study we inferred the migration history of HIV-1 subtype B by way of a phylogeography of viral sequences sampled from 16 European countries and Israel. Migration events were inferred from viral phylogenies by character reconstruction using parsimony. With regard to the spatial dispersal of the HIV subtype B sequences across viral phylogenies, in most of the countries in Europe the epidemic was introduced by multiple sources and subsequently spread within local networks. Poland provides an exception where most of the infections were the result of a single point introduction. According to the significant migratory pathways, we show that there are considerable differences across Europe. Specifically, Greece, Portugal, Serbia and Spain, provide sources shedding HIV-1; Austria, Belgium and Luxembourg, on the other hand, are migratory targets, while for Denmark, Germany, Italy, Israel, Norway, the Netherlands, Sweden, Switzerland and the UK we inferred significant bidirectional migration. For Poland no significant migratory pathways were inferred.</p> <p>Conclusion</p> <p>Subtype B phylogeographies provide a new insight about the geographical distribution of viral lineages, as well as the significant pathways of virus dispersal across Europe, suggesting that intervention strategies should also address tourists, travellers and migrants.</p

Comparisons of cognitive ability and job attitudes of older and younger workers

Purpose: Advancing knowledge about effectively managing the ageing workforce and ensuring economic sustainability for a growing retired cohort is a recognised priority for organisational health researchers, employers and governments. The purpose of this paper is to test social perceptions that older workers' cognitive performance and job attitudes compare adversely to their younger colleagues.\ud \ud Design/methodology/approach: The research assessed samples of older and younger workers in objective tests of cognitive abilities and subjective job attitudes. An opportunity sampling method was employed to recruit a heterogeneous group of participants in Australia (n=172).\ud \ud Findings: No significant differences in cognitive ability between the groups were identified; older workers were as cognitively skilled for their job as their younger colleagues. No significant group difference for perceptions of social support, job commitment, job satisfaction or turnover intentions was identified.\ud \ud Research limitations/implications: The cross-sectional research design adopted by this research prevented a more detailed examination of the data in terms of causal relationships. While the cognitive testing provided objective rather than subjective data and, therefore, is not as susceptible to response biases such as common method variance, the small sample who undertook the cognitive testing is acknowledged as a research limitation.\ud \ud Social implications: This research has implications for the reduction in unemployment of older workers and directly addresses the social issues of an ageing labour force.\ud \ud Originality/value: The paper demonstrates that stereotypical assumptions concerning inadequate performance and low job commitment commonly attributed to older workers are not in fact indicative of all ageing employees

The relationship of social support with well-being outcomes via work–family conflict: Moderating effects of gender, dependants and nationality

The impact of work–family conflict on well-being outcomes is well established, as is the role of social support in buffering perceptions of conflict. What is less well understood is how these relationships vary for different groups of respondents. Using a two-wave longitudinal design with a 12-month time lag and samples of employees (total N = 2183) from Australia, New Zealand, China and Hong Kong, the present research investigated whether the mediating relationships between social support, work–family conflict and well-being outcomes were moderated by gender, geographical region and the presence of dependants in the household. Supervisor support and family support were associated with lower work–family conflict, and hence reduced psychological strain and increased job and family satisfaction, for women and for employees in China and Hong Kong, but not for employees in Australia and New Zealand. However, the presence of dependants was not a significant moderator. Our findings illustrate the importance of exploring gender and national differences in work–family conflict research, particularly the investigation of cross-domain effects.This research was supported by the Australian Research Council Discovery Project Grant Scheme (grant number: DP0770109)

The relationship of social support with well-being outcomes via work-family conflict: moderating effects of gender, dependants and nationality

The impact of work-family conflict on well-being outcomes is well established, as is the role of social support in buffering perceptions of conflict. What is less well understood is how these relationships vary for different groups of respondents. Using a two-wave longitudinal design with a 12-month time lag and samples of employees (total N = 2183) from Australia, New Zealand, China and Hong Kong, the present research investigated whether the mediating relationships between social support, work-family conflict and well-being outcomes were moderated by gender, geographical region and the presence of dependants in the household. Supervisor support and family support were associated with lower work-family conflict, and hence reduced psychological strain and increased job and family satisfaction, for women and for employees in China and Hong Kong, but not for employees in Australia and New Zealand. However, the presence of dependants was not a significant moderator. Our findings illustrate the importance of exploring gender and national differences in work-family conflict research, particularly the investigation of cross-domain effects

Connecting the person with dementia and family: a feasibility study of a telepresence robot

Background: Maintenance of communication is important for people with dementia living in long-term care. The purpose of this study was to assess the feasibility of using “Giraff”, a telepresence robot to enhance engagement between family and a person with dementia living in long-term care. Methods: A mixed-methods approach involving semi-structured interviews, call records and video observational data was used. Five people with dementia and their family member participated in a discussion via the Giraff robot for a minimum of six times over a six-week period. A feasibility framework was used to assess feasibility and included video analysis of emotional response and engagement. Results: Twenty-six calls with an average duration of 23 mins took place. Residents showed a general state of positive emotions across the calls with a high level of engagement and a minimal level of negative emotions. Participants enjoyed the experience and families reported that the Giraff robot offered the opportunity to reduce social isolation. A number of software and hardware challenges were encountered. Conclusions: Participants perceived this novel approach to engage families and people with dementia as a feasible option. Participants were observed and also reported to enjoy the experience. The technical challenges identified have been improved in a newer version of the robot. Future research should include a feasibility trial of longer duration, with a larger sample and a cost analysis