787 research outputs found
Intelligent opinion mining and sentiment analysis using artificial neural networks
The article formulates a rigorously developed concept of opinion mining and sentiment analysis using hybrid neural networks. This conceptual method for processing natural-language text enables a variety of analyses of the subjective content of texts. It is a methodology based on hybrid neural networks for detecting subjective content and potential opinions, as well as a method which allows us to classify different opinion type and sentiment score classes. Moreover, a general processing scheme, using neural networks, for sentiment and opinion analysis has been presented. Furthermore, a methodology which allows us to determine sentiment regression has been devised. The paper proposes a method for classification of the text being examined based on the amount of positive, neutral or negative opinion it contains. The research presented here offers the possibility of motivating and inspiring further development of the methods that have been elaborated in this paper.Stuart, KDC.; Majewski, M. (2015). Intelligent opinion mining and sentiment analysis using artificial neural networks. Lecture Notes in Computer Science. 9492:103-110. doi:10.1007/978-3-319-26561-2_13S1031109492Feldman, R.: Techniques and applications for sentiment analysis. Commun. ACM 56(4), 82–89 (2013)Taboada, M., Brooke, J., Tofiloski, M., Voll, K., Stede, M.: Lexicon-based methods for sentiment analysis. Comput. Linguist. 37(2), 267–307 (2011)Mohammad, S.M., Turney, P.D.: Crowdsourcing a word-emotion association lexicon. Comput. Intell. 29(3), 436–465 (2013)Chen, H., Zimbra, D.: AI and opinion mining. IEEE Intell. Syst. 25(3), 74–80 (2010)Majewski, M., Zurada, J.M.: Sentence recognition using artificial neural networks. Knowl. Based Syst. 21(7), 629–635 (2008)Kacalak, W., Stuart, K.D., Majewski, M.: Intelligent natural language processing. In: Jiao, L., Wang, L., Gao, X., Liu, J., Wu, F. (eds.) ICNC 2006. LNCS, vol. 4221, pp. 584–587. Springer, Heidelberg (2006)Kacalak, W., Stuart, K., Majewski, M.: Selected problems of intelligent handwriting recognition. In: Melin, P., Castillo, O., RamÃrez, E.G., Kacprzyk, J., Pedrycz, W. (eds.) IFSA 2007. Advances in Soft Computing, vol. 41, pp. 298–305. Springer, Cancun (2007)Stuart, K.D., Majewski, M.: Selected problems of knowledge discovery using artificial neural networks. In: Liu, D., Fei, S., Hou, Z., Zhang, H., Sun, C. (eds.) ISNN 2007, Part III. LNCS, vol. 4493, pp. 1049–1057. Springer, Heidelberg (2007)Stuart, K., Majewski, M.: A new method for intelligent knowledge discovery. In: Castillo, O., Melin, P., Ross, O.M., Cruz, R.S., Pedrycz, W., Kacprzyk, J. (eds.) IFSA 2007. Advances in Soft Computing, vol. 42, pp. 721–729. Springer, Heidelberg (2007)Stuart, K.D., Majewski, M.: Artificial creativity in linguistics using evolvable fuzzy neural networks. In: Hornby, G.S., Sekanina, L., Haddow, P.C. (eds.) ICES 2008. LNCS, vol. 5216, pp. 437–442. Springer, Heidelberg (2008)Stuart, K.D., Majewski, M.: Evolvable neuro-fuzzy system for artificial creativity in linguistics. In: Huang, D.-S., Wunsch II, D.C., Levine, D.S., Jo, K.-H. (eds.) ICIC 2008. LNCS (LNAI), vol. 5227, pp. 46–53. Springer, Heidelberg (2008)Stuart, K.D., Majewski, M., Trelis, A.B.: Selected problems of intelligent corpus analysis through probabilistic neural networks. In: Zhang, L., Lu, B.-L., Kwok, J. (eds.) ISNN 2010, Part II. LNCS, vol. 6064, pp. 268–275. Springer, Heidelberg (2010)Stuart, K.D., Majewski, M., Trelis, A.B.: Intelligent semantic-based system for corpus analysis through hybrid probabilistic neural networks. In: Liu, D., Zhang, H., Polycarpou, M., Alippi, C., He, H. (eds.) ISNN 2011, Part I. LNCS, vol. 6675, pp. 83–92. Springer, Heidelberg (2011)Specht, D.F.: Probabilistic neural networks. Neural Netw. 3(1), 109–118 (1990)Specht, D.F.: A general regression neural network. IEEE Trans. Neural Netw. 2(6), 568–576 (1991
Causes of Death Following PCI Versus CABG in Complex CAD 5-Year Follow-Up of SYNTAX
AbstractBackgroundThere are no data available on specific causes of death from randomized trials that have compared coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI).ObjectivesThe purpose of this study was to investigate specific causes of death, and its predictors, after revascularization for complex coronary disease in patients.MethodsAn independent Clinical Events Committee consisting of expert physicians who were blinded to the study treatment subclassified causes of death as cardiovascular (cardiac and vascular), noncardiovascular, or undetermined according to the trial protocol. Cardiac deaths were classified as sudden cardiac, related to myocardial infarction (MI), and other cardiac deaths.ResultsIn the randomized cohort, there were 97 deaths after CABG and 123 deaths after PCI during a 5-year follow-up. After CABG, 49.4% of deaths were cardiovascular, with the greatest cause being heart failure, arrhythmia, or other causes (24.6%), whereas after PCI, the majority of deaths were cardiovascular (67.5%) and as a result of MI (29.3%). The cumulative incidence rates of all-cause death were not significantly different between CABG and PCI (11.4% vs. 13.9%, respectively; p = 0.10), whereas there were significant differences in terms of cardiovascular (5.8% vs. 9.6%, respectively; p = 0.008) and cardiac death (5.3% vs. 9.0%, respectively; p = 0.003), which were caused primarily by a reduction in MI-related death with CABG compared with PCI (0.4% vs. 4.1%, respectively; p <0.0001). Treatment with PCI versus CABG was an independent predictor of cardiac death (hazard ratio: 1.55; 95% confidence interval: 1.09 to 2.33; p = 0.045). The difference in MI-related death was seen largely in patients with diabetes, 3-vessel disease, or high SYNTAX (TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries) trial scores.ConclusionsDuring a 5-year follow-up, CABG in comparison with PCI was associated with a significantly reduced rate of MI-related death, which was the leading cause of death after PCI. Treatments following PCI should target reducing post-revascularization spontaneous MI. Furthermore, secondary preventive medication remains essential in reducing events post-revascularization. (TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries [SYNTAX]; NCT00114972
Preregistration of secondary data analysis:A template and tutorial
Multivariate analysis of psychological dat
Applied Interventions in the Prevention and Treatment of Obesity Through the Research of Professor Jane Wardle
Purpose of Review
Obesity presents a challenge for practitioners, policy makers, researchers and for those with obesity themselves. This review focuses on psychological approaches to its management and prevention in children and adults.
Recent Findings
Through exploring the work of the late Professor Jane Wardle, we look at the earliest behavioural treatment approaches and how psychological theory has been used to develop more contemporary approaches, for example incorporating genetic feedback and habit formation theory into interventions. We also explore how Jane has challenged thinking about the causal pathways of obesity in relation to eating behaviour. Beyond academic work, Jane was an advocate of developing interventions which had real-world applications.
Summary
Therefore, we discuss how she not only developed new interventions but also made these widely available and the charity that she established
Exercise interveNtion outdoor proJect in the cOmmunitY for older people - The ENJOY Senior Exercise Park project translation research protocol
Background: Creating inclusive and accessible outdoor environments that provide and encourage opportunities for older adults to engage in physical activity and social interaction is important for healthy ageing. The Senior Exercise Park is outdoor exercise equipment designed specifically for use by older people that provides physical and social benefits for older people in the community, and has the potential to be used widely as a sustainable mode of physical activity. The aim of this study is to implement and evaluate the effects of sustained engagement through the use of a community-based novel outdoor physical activity program (purpose-built exercise park) for older people on physical, mental and social health and physical activity outcomes (the ENJOY project).
Methods: This is a prospective pre-post design study with 12 months follow up. Adults aged ≥60 years will be recruited from the general community from the suburbs close to the Senior Exercise Parks locations in Melbourne. Participants will undergo a 12 week structured supervised physical activity program using the outdoor Senior Exercise Park equipment followed by 6 months unstructured physical activity program. Participants will be assessed at baseline, 3, 9, and 12 months. The following outcomes will be assessed: physical activity, physical function, psychosocial and mental health outcomes, falls risk and falls occurrence, participants' feedback and satisfaction, and health care resource use.
Discussion: The ENJOY trial is designed to operate in a community setting with local government engagement to maximise the usage of the exercise park and provide an outdoor space for older people to be physically active. This project will evaluate the effectiveness and sustainability of the outdoor exercise park on a range of health outcomes and its long-term usability in the community.
Trial registration: This trial is prospectively registered with the Australian New Zealand Clinical Trials Registry. Trial registration number ACTRN12618001727235 registered 18th of October 2018
Marine Macroalgal Diversity Assessment of Saba Bank, Netherlands Antilles
Background: Located in the Dutch Windward Islands, Saba Bank is a flat-topped seamount (20–45 m deep in the shallower regions). The primary goals of the survey were to improve knowledge of biodiversity for one of the world’s most significant, but little-known, seamounts and to increase basic data and analyses to promote the development of an improved management plan. Methodology/Principal Findings: Our team of three divers used scuba to collect algal samples to depths of 50 m at 17 dive sites. Over 360 macrophyte specimens (12 putative new species) were collected, more than 1,000 photographs were taken in truly exceptional habitats, and three astonishing new seaweed community types were discovered. These included: (1) ‘‘Field of Greens’ ’ (N 17u30.6209, W63u27.7079) dominated by green seaweeds as well as some filamentous reds, (2) ‘‘Brown Town’ ’ (N 17u28.0279, W63u14.9449) dominated by large brown algae, and (3) ‘‘Seaweed City’ ’ (N 17u26.4859, W63u16.8509) with a diversity of spectacular fleshy red algae. Conclusions/Significance: Dives to 30 m in the more two-dimensional interior habitats revealed particularly robust specimens of algae typical of shallower seagrass beds, but here in the total absence of any seagrasses (seagrasses generally do not grow below 20 m). Our preliminary estimate of the number of total seaweed species on Saba Bank ranges from a minimum of 150 to 200. Few filamentous and thin sheet forms indicative of stressed or physically disturbed environments were observed. A more precise number still awaits further microscopic and molecular examinations in the laboratory. The expedition, while intensive, has only scratched the surface of this unique submerged seamount/atoll
Functional and Structural Insights Revealed by Molecular Dynamics Simulations of an Essential RNA Editing Ligase in Trypanosoma brucei
RNA editing ligase 1 (TbREL1) is required for the survival of both the insect and bloodstream forms of Trypanosoma brucei, the parasite responsible for the devastating tropical disease African sleeping sickness. The type of RNA editing that TbREL1 is involved in is unique to the trypanosomes, and no close human homolog is known to exist. In addition, the high-resolution crystal structure revealed several unique features of the active site, making this enzyme a promising target for structure-based drug design. In this work, two 20 ns atomistic molecular dynamics (MD) simulations are employed to investigate the dynamics of TbREL1, both with and without the ATP substrate present. The flexibility of the active site, dynamics of conserved residues and crystallized water molecules, and the interactions between TbREL1 and the ATP substrate are investigated and discussed in the context of TbREL1's function. Differences in local and global motion upon ATP binding suggest that two peripheral loops, unique to the trypanosomes, may be involved in interdomain signaling events. Notably, a significant structural rearrangement of the enzyme's active site occurs during the apo simulations, opening an additional cavity adjacent to the ATP binding site that could be exploited in the development of effective inhibitors directed against this protozoan parasite. Finally, ensemble averaged electrostatics calculations over the MD simulations reveal a novel putative RNA binding site, a discovery that has previously eluded scientists. Ultimately, we use the insights gained through the MD simulations to make several predictions and recommendations, which we anticipate will help direct future experimental studies and structure-based drug discovery efforts against this vital enzyme
Aneurysm of antecubital vein: an unusual complication of peripheral intravenous cannulation
<p>Abstract</p> <p>Background</p> <p>Intravenous cannulation is a very common procedure. Venous aneurysm secondary to peripheral intravenous cannulation is extremely rare. Moreover, venous aneurysm can mimic other conditions and may confuse the issue.</p> <p>Case presentation</p> <p>We describe a case of a 45-year-old woman who was referred with the diagnosis of varicose vein of right arm. A history of intravenous cannulation at the same site was noted that raised suspicion. The swelling was compressible and turned out to be a venous aneurysm. The lesion was completely excised. Postoperative recovery was uneventful. Histology findings were in conformity with the preoperative diagnosis.</p> <p>Conclusion</p> <p>Caution should be exercised in diagnosing varicose vein at a site that bears a history of intravenous cannulation. The case also raises an important issue regarding consent. Should patients undergoing peripheral intravenous cannulation be warned of this rare complication?</p
Quantifying the Ocean, Freshwater and Human Effects on Year-to-Year Variability of One-Sea-Winter Atlantic Salmon Angled in Multiple Norwegian Rivers
Many Atlantic salmon, Salmo salar, populations are decreasing throughout the species' distributional range probably due to several factors acting in concert. A number of studies have documented the influence of freshwater and ocean conditions, climate variability and human impacts resulting from impoundment and aquaculture. However, most previous research has focused on analyzing single or only a few populations, and quantified isolated effects rather than handling multiple factors in conjunction. By using a multi-river mixed-effects model we estimated the effects of oceanic and river conditions, as well as human impacts, on year-to-year and between-river variability across 60 time series of recreational catch of one-sea-winter salmon (grilse) from Norwegian rivers over 29 years (1979–2007). Warm coastal temperatures at the time of smolt entrance into the sea and increased water discharge during upstream migration of mature fish were associated with higher rod catches of grilse. When hydropower stations were present in the course of the river systems the strength of the relationship with runoff was reduced. Catches of grilse in the river increased significantly following the reduction of the harvesting of this life-stage at sea. However, an average decreasing temporal trend was still detected and appeared to be stronger in the presence of salmon farms on the migration route of smolts in coastal/fjord areas. These results suggest that both ocean and freshwater conditions in conjunction with various human impacts contribute to shape interannual fluctuations and between-river variability of wild Atlantic salmon in Norwegian rivers. Current global change altering coastal temperature and water flow patterns might have implications for future grilse catches, moreover, positioning of aquaculture facilities as well as the implementation of hydropower schemes or other encroachments should be made with care when implementing management actions and searching for solutions to conserve this species
Substance abuse and intimate partner violence: treatment considerations
Given the increased use of marital- and family-based treatments as part of treatment for alcoholism and other drug disorders, providers are increasingly faced with the challenge of addressing intimate partner violence among their patients and their intimate partners. Yet, effective options for clinicians who confront this issue are extremely limited. While the typical response of providers is to refer these cases to some form of batterers' treatment, three fundamental concerns make this strategy problematic: (1) most of the agencies that provide batterers' treatment only accept individuals who are legally mandated to complete their programs; (2) among programs that do accept nonmandated patients, most substance-abusing patients do not accept such referrals or drop out early in the treatment process; and (3) available evidence suggests these programs may not be effective in reducing intimate partner violence. Given these very significant concerns with the current referral approach, coupled with the high incidence of IPV among individuals entering substance abuse treatment, providers need to develop strategies for addressing IPV that can be incorporated and integrated into their base intervention packages
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