What is the Difference Between Depression and Burnout? An Ongoing Debate

Il burnout è concepito come una sindrome che si sviluppa in risposta a condizioni di lavoro cronicamente avverse. Si ritiene che il burnout comporti esaurimento emotivo, depersonalizzazione e riduzione della realizzazione personale. Storicamente, tuttavia, il burnout è stato difficile da separare dalla depressione. In effetti, i sintomi del burnout coincidono con i sintomi della depressione. L\u27evidenza della validità discriminante del burnout nei confronti della depressione è debole, sia a livello empirico sia a livello teorico. L\u27esaurimento emotivo, il nucleo del burnout, riflette una combinazione di umore depresso e affaticamento / perdita di energia e si correla molto bene con altri sintomi depressivi. I fattori lavorativi di rischio per il burnout sono i medesimi fattori predittivi della depressione. I fattori individuali di rischio per la depressione (per es., episodi depressivi pregressi) sono gli stessi del burnout. Nel complesso, è probabile che il burnout rifletta un processo depressivo “classico” che si manifesta in reazione a uno stress irrisolvibile. Burnout has been viewed as a syndrome developing in response to chronically adverse working conditions. Burnout is thought to comprise emotional exhaustion, depersonalization, and reduced personal accomplishment. Historically, however, burnout has been difficult to separate from depression. Indeed, the symptoms of burnout coincide with symptoms of depression. Evidence for the discriminant validity of burnout with regard to depression has been weak, both at an empirical and a theoretical level. Emotional exhaustion, the core of burnout, itself reflects a combination of depressed mood and fatigue/loss of energy and correlates very highly with other depressive symptoms. Work-related risk factors for burnout are also predictors of depression. Individual risk factors for depression (e.g., past depressive episodes) are also predictors of burnout. Overall, burnout is likely to reflect a “classical” depressive process unfolding in reaction to unresolvable stress

DR(eye)VE: a Dataset for Attention-Based Tasks with Applications to Autonomous and Assisted Driving

Autonomous and assisted driving are undoubtedly hot topics in computer vision. However, the driving task is extremely complex and a deep understanding of drivers' behavior is still lacking. Several researchers are now investigating the attention mechanism in order to define computational models for detecting salient and interesting objects in the scene. Nevertheless, most of these models only refer to bottom up visual saliency and are focused on still images. Instead, during the driving experience the temporal nature and peculiarity of the task influence the attention mechanisms, leading to the conclusion that real life driving data is mandatory. In this paper we propose a novel and publicly available dataset acquired during actual driving. Our dataset, composed by more than 500,000 frames, contains drivers' gaze fixations and their temporal integration providing task-specific saliency maps. Geo-referenced locations, driving speed and course complete the set of released data. To the best of our knowledge, this is the first publicly available dataset of this kind and can foster new discussions on better understanding, exploiting and reproducing the driver's attention process in the autonomous and assisted cars of future generations

Cyclotron lines in X-ray pulsars as a probe of relativistic plasmas in superstrong magnetic fields

The systematic search for the presence of cyclotron lines in the spectra of accreting X-ray pulsars is being carried on with the BeppoSAX satellite since the beginning of the mission. These highly successful observations allowed the detection of cyclotron lines in many of the accreting X-ray pulsars observed. Some correlations between the different measured parameters were found. We present these correlations and discuss them in the framework of the current theoretical scenario for the X-ray emission from these sources.Comment: 5 pages, 2 figures, uses aipproc.sty, to appear in Proceeding of Fifth Compton Symposiu

Web Content Search and Adaptation for IDTV: One Step Forward in the Mediamorphosis Process toward Personal-TV

We are on the threshold of a mediamorphosis that will revolutionize the way we interact with our TV sets. The combination between interactive digital TV (IDTV) and the Web fosters the development of new interactive multimedia services enjoyable even through a TV screen and a remote control. Yet, several design constraints complicate the deployment of this new pattern of services. Prominent unresolved issues involve macro-problems such as collecting information on the Web based on users' preferences and appropriately presenting retrieved Web contents on the TV screen. To this aim, we propose a system able to dynamically convey contents from the Web to IDTV systems. Our system presents solutions both for personalized Web content search and automatic TV-format adaptation of retrieved documents. As we demonstrate through two case study applications, our system merges the best of IDTV and Web domains spinning the TV mediamorphosis toward the creation of the personal-TV concept

Superconducting tunable flux qubit with direct readout scheme

We describe a simple and efficient scheme for the readout of a tunable flux qubit, and present preliminary experimental tests for the preparation, manipulation and final readout of the qubit state, performed in incoherent regime at liquid Helium temperature. The tunable flux qubit is realized by a double SQUID with an extra Josephson junction inserted in the large superconducting loop, and the readout is performed by applying a current ramp to the junction and recording the value for which there is a voltage response, depending on the qubit state. This preliminary work indicates the feasibility and efficiency of the scheme.Comment: 10 pages, 5 figure

Ascending aortic aneurysm in a patient with bicuspid aortic valve, positive history of systemic autoimmune diseases and common genetic factors: a case report

The bicuspid aortic valve (BAV) and specific systemic autoimmune diseases are associated with cardiovascular manifestation, including aortic aneurysm. We reported a case of 64 year-old patient with BAV and a history of ankylosing spondylitis (AS) and systemic lupus erythematosus (SLE), and who developed ascending thoracic aortic aneurysm. The patient presented also the homozygosity for genetic variants of MMP9, ACE, MTHFR and PAI-1 genes. Gene-environmental interactions may represent an additional pathogenetic dimension in the still challenging management of the abnormalities of the aortic wall, including dilatation, aneurysm and dissection

A serine protease secreted from Bacillus subtilis cleaves human plasma transthyretin to generate an amyloidogenic fragment

Aggregation of human wild-type transthyretin (hTTR), a homo-tetrameric plasma protein, leads to acquired senile systemic amyloidosis (SSA), recently recognised as a major cause of cardiomyopathies in 1-3% older adults. Fragmented hTTR is the standard composition of amyloid deposits in SSA, but the protease(s) responsible for amyloidogenic fragments generation in vivo is(are) still elusive. Here, we show that subtilisin secreted from Bacillus subtilis, a gut microbiota commensal bacterium, translocates across a simulated intestinal epithelium and cleaves hTTR both in solution and human plasma, generating the amyloidogenic fragment hTTR(59-127), which is also found in SSA amyloids in vivo. To the best of our knowledge, these findings highlight a novel pathogenic mechanism for SSA whereby increased permeability of the gut mucosa, as often occurs in elderly people, allows subtilisin (and perhaps other yet unidentified bacterial proteases) to reach the bloodstream and trigger generation of hTTR fragments, acting as seeding nuclei for preferential amyloid fibrils deposition in the heart. Peterle et al. show that a subtilisin like serine protease secreted from gut microbiota Bacillus subtilis cleaves the wild-type human transthyretin (hTTR) to generate an amyloidogenic peptide. High propensity of the hTTR fragment to form pathogenic protein aggregates implicates the serine protease in the pathogenesis of acquired senile systemic amyloidosis

The Highly Energetic Expansion of SN2010bh Associated with GRB 100316D

We present the spectroscopic and photometric evolution of the nearby (z = 0.059) spectroscopically confirmed type Ic supernova, SN 2010bh, associated with the soft, long-duration gamma-ray burst (X-ray flash) GRB 100316D. Intensive follow-up observations of SN 2010bh were performed at the ESO Very Large Telescope (VLT) using the X-shooter and FORS2 instruments. Owing to the detailed temporal coverage and the extended wavelength range (3000--24800 A), we obtained an unprecedentedly rich spectral sequence among the hypernovae, making SN 2010bh one of the best studied representatives of this SN class. We find that SN 2010bh has a more rapid rise to maximum brightness (8.0 +/- 1.0 rest-frame days) and a fainter absolute peak luminosity (L_bol~3e42 erg/s) than previously observed SN events associated with GRBs. Our estimate of the ejected (56)Ni mass is 0.12 +/- 0.02 Msun. From the broad spectral features we measure expansion velocities up to 47,000 km/s, higher than those of SNe 1998bw (GRB 980425) and 2006aj (GRB 060218). Helium absorption lines He I lambda5876 and He I 1.083 microm, blueshifted by ~20,000--30,000 km/s and ~28,000--38,000 km/s, respectively, may be present in the optical spectra. However, the lack of coverage of the He I 2.058 microm line prevents us from confirming such identifications. The nebular spectrum, taken at ~186 days after the explosion, shows a broad but faint [O I] emission at 6340 A. The light-curve shape and photospheric expansion velocities of SN 2010bh suggest that we witnessed a highly energetic explosion with a small ejected mass (E_k ~ 1e52 erg and M_ej ~ 3 Msun). The observed properties of SN 2010bh further extend the heterogeneity of the class of GRB supernovae.Comment: 37 pages and 12 figures (one-column pre-print format), accepted for publication in Ap