55 research outputs found
Development of a telescope for medium-energy gamma-ray astronomy
The Advanced Energetic Pair Telescope (AdEPT) is being developed at GSFC as a future NASA MIDEX mission to explore the medium-energy (5–200 MeV) gamma-ray range. The enabling technology for AdEPT is the Three- Dimensional Track Imager (3-DTI), a gaseous time projection chamber. The high spatial resolution 3-D electron tracking of 3-DTI enables AdEPT to achieve high angular resolution gamma-ray imaging via pair production and triplet production (pair production on electrons) in the medium-energy range. The low density and high spatial resolution of 3-DTI allows the electron positron track directions to be measured before they are dominated by Coulomb scattering. Further, the significant reduction of Coulomb scattering allows AdEPT to be the first medium-energy gamma-ray telescope to have high gamma-ray polarization sensitivity. We review the science goals that can be addressed with a medium-energy pair telescope, how these goals drive the telescope design, and the realization of this design with AdEPT. The AdEPT telescope for a future MIDEX mission is envisioned as a 8 m3 active volume filled with argon at 2 atm. The design and performance of the 3-DTI detectors for the AdEPT telescope are described as well as the outstanding instrument challenges that need to be met for the AdEPT mission
Ribbons on the CBR Sky: A Powerful Test of a Baryon Symmetric Universe
If the Universe consists of domains of matter and antimatter, annihilations
at domain interfaces leave a distinctive imprint on the Cosmic Background
Radiation (CBR) sky. The signature is anisotropies in the form of long, thin
ribbons of width , separated by angle where L is the characteristic domain size, and
y-distortion parameter . Such a pattern could potentially be
detected by the high-resolution CBR anisotropy experiments planned for the next
decade, and such experiments may finally settle the question of whether or not
our Hubble volume is baryon symmetric.Comment: LaTeX, 10 pages, 4 figures in epsf. Revised version corrects a couple
of relevant mistake
New hadrons as ultra-high energy cosmic rays
Ultra-high energy cosmic ray (UHECR) protons produced by uniformly
distributed astrophysical sources contradict the energy spectrum measured by
both the AGASA and HiRes experiments, assuming the small scale clustering of
UHECR observed by AGASA is caused by point-like sources. In that case, the
small number of sources leads to a sharp exponential cutoff at the energy
E<10^{20} eV in the UHECR spectrum. New hadrons with mass 1.5-3 GeV can solve
this cutoff problem. For the first time we discuss the production of such
hadrons in proton collisions with infrared/optical photons in astrophysical
sources. This production mechanism, in contrast to proton-proton collisions,
requires the acceleration of protons only to energies E<10^{21} eV. The diffuse
gamma-ray and neutrino fluxes in this model obey all existing experimental
limits. We predict large UHE neutrino fluxes well above the sensitivity of the
next generation of high-energy neutrino experiments. As an example we study
hadrons containing a light bottom squark. These models can be tested by
accelerator experiments, UHECR observatories and neutrino telescopes.Comment: 17 pages, revtex style; v2: shortened, as to appear in PR
Nearby quasar remnants and ultra-high energy cosmic rays
As recently suggested, nearby quasar remnants are plausible sites of
black-hole based compact dynamos that could be capable of accelerating
ultra-high energy cosmic rays (UHECRs). In such a model, UHECRs would originate
at the nuclei of nearby dead quasars, those in which the putative underlying
supermassive black holes are suitably spun-up. Based on galactic optical
luminosity, morphological type, and redshift, we have compiled a small sample
of nearby objects selected to be highly luminous, bulge-dominated galaxies,
likely quasar remnants. The sky coordinates of these galaxies were then
correlated with the arrival directions of cosmic rays detected at energies EeV. An apparently significant correlation appears in our data. This
correlation appears at closer angular scales than those expected when taking
into account the deflection caused by typically assumed IGM or galactic
magnetic fields over a charged particle trajectory. Possible scenarios
producing this effect are discussed, as is the astrophysics of the quasar
remnant candidates. We suggest that quasar remnants be also taken into account
in the forthcoming detailed search for correlations using data from the Auger
Observatory.Comment: 2 figures, 4 tables, 11 pages. Final version to appear in Physical
Review
Spinal involvement in mucopolysaccharidosis IVA (Morquio-Brailsford or Morquio A syndrome): presentation, diagnosis and management.
Mucopolysaccharidosis IVA (MPS IVA), also known as Morquio-Brailsford or Morquio A syndrome, is a lysosomal storage disorder caused by a deficiency of the enzyme N-acetyl-galactosamine-6-sulphate sulphatase (GALNS). MPS IVA is multisystemic but manifests primarily as a progressive skeletal dysplasia. Spinal involvement is a major cause of morbidity and mortality in MPS IVA. Early diagnosis and timely treatment of problems involving the spine are critical in preventing or arresting neurological deterioration and loss of function. This review details the spinal manifestations of MPS IVA and describes the tools used to diagnose and monitor spinal involvement. The relative utility of radiography, computed tomography (CT) and magnetic resonance imaging (MRI) for the evaluation of cervical spine instability, stenosis, and cord compression is discussed. Surgical interventions, anaesthetic considerations, and the use of neurophysiological monitoring during procedures performed under general anaesthesia are reviewed. Recommendations for regular radiological imaging and neurologic assessments are presented, and the need for a more standardized approach for evaluating and managing spinal involvement in MPS IVA is addressed
Search for diffuse neutrino flux from astrophysical sources with MACRO
Many galactic and extragalactic astrophysical sources are currently
considered promising candidates as high energy neutrino emitters. Astrophysical
neutrinos can be detected as upward-going muons produced in charged-current
interactions with the medium surrounding the detector. The expected neutrino
fluxes from various models start to dominate on the atmospheric neutrino
background at neutrino energies above some tens of TeV. We present the results
of a search for an excess of high energy upward-going muons among the sample of
data collected by MACRO during ~5.8 years of effective running time. No
significant evidence for this signal was found. As a consequence, an upper
limit on the flux of upward-going muons from high-energy neutrinos was set at
the level of 1.7 10^(-14) cm^(-2) s^(-1) sr^(-1).
The corresponding upper limit for the diffuse neutrino flux was evaluated
assuming a neutrino power law spectrum. Our result was compared with
theoretical predictions and upper limits from other experiments.Comment: 19 pages, 8 figures, 2 table
Fermi Large Area Telescope Constraints on the Gamma-ray Opacity of the Universe
The Extragalactic Background Light (EBL) includes photons with wavelengths
from ultraviolet to infrared, which are effective at attenuating gamma rays
with energy above ~10 GeV during propagation from sources at cosmological
distances. This results in a redshift- and energy-dependent attenuation of the
gamma-ray flux of extragalactic sources such as blazars and Gamma-Ray Bursts
(GRBs). The Large Area Telescope onboard Fermi detects a sample of gamma-ray
blazars with redshift up to z~3, and GRBs with redshift up to z~4.3. Using
photons above 10 GeV collected by Fermi over more than one year of observations
for these sources, we investigate the effect of gamma-ray flux attenuation by
the EBL. We place upper limits on the gamma-ray opacity of the Universe at
various energies and redshifts, and compare this with predictions from
well-known EBL models. We find that an EBL intensity in the optical-ultraviolet
wavelengths as great as predicted by the "baseline" model of Stecker et al.
(2006) can be ruled out with high confidence.Comment: 42 pages, 12 figures, accepted version (24 Aug.2010) for publication
in ApJ; Contact authors: A. Bouvier, A. Chen, S. Raino, S. Razzaque, A.
Reimer, L.C. Reye
The effect of major depression on participation in preventive health care activities
<p>Abstract</p> <p>Background</p> <p>The objective of this study was to determine whether major depressive episodes (MDE) contribute to a lower rate of participation in three prevention activities: blood pressure checks, mammograms and Pap tests.</p> <p>Methods</p> <p>The data source for this study was the Canadian National Population Health Survey (NPHS), a longitudinal study that started in 1994 and has subsequently re-interviewed its participants every two years. The NPHS included a short form version of the Composite International Diagnostic Interview (CIDI-SF) to assess past year MDE and also collected data on participation in preventive activities. Initially, we examined whether respondents with MDE in a particular year were less likely to participate in screening during that same year. In order to assess whether MDE negatively altered the pattern of participation, those successfully screened at the baseline interview in 1994 were identified and divided into cohorts depending on their MDE status. Proportional hazard models were used to quantify the effect of MDE on subsequent participation in screening.</p> <p>Results</p> <p>No effect of MDE on participation in the three preventive activities was identified either in the cross-sectional or longitudinal analysis. Adjustment for a set of relevant covariates did not alter this result.</p> <p>Conclusion</p> <p>Whereas MDE might be expected to reduce the frequency of participation in screening activities, no evidence for this was found in the current analysis. Since people with MDE may contact the health system more frequently, this may offset any tendency of the illness itself to reduce participation in screening.</p
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