6,984 research outputs found

    A hybrid computer study of a dynamic ship positioning system

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    Hybrid computer program for dynamic ship positioning syste

    The Present Status and Probable Future of the Indians of Puget Sound

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    "We have robbed the Indian of his lands and waters by false and fair means; we have forced him to live in an atmosphere of totally different customs and ideals; it would be, therefore, far less than justice if we fail to do all we can to help him fit himself for his new life.

    Attributes of Entrepreneurs: Personality Versus Perspective

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    This presentation will address the general conference topic: what are the attributes of successful entrepreneurs? The presentation will begin with a brief history of the term - Entrepreneur, including its evolution from a descriptor of farmers in the 1800s who faced price-uncertainty when planting crops each season -- to the 20th century definition of an entrepreneur as the instigator of the creative destruction that brings about fundamental industry change. The presentation will briefly review the large body of research that has investigated entrepreneurial personalities -- and conclude with the key point that successful entrepreneurs and successful managers do not differ in personality, but they do differ in perspective. These differences in perspective are very real, can be addressed in the classroom, and can serve as the basis for curriculum development. The presentation will conclude with a discussion of the entrepreneurial process -- the process of moving inventions to the market place as innovations. The elements of the entrepreneurial process will be discussed, showing the key role that an entrepreneurial perspective can play in laying a foundation for success

    Continuously wavelength-tunable high harmonic generation via soliton dynamics

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    We report generation of high harmonics in a gas-jet pumped by pulses self-compressed in a He-filled hollow-core photonic crystal fiber through the soliton effect. The gas-jet is placed directly at the fiber output. As the energy increases the ionization-induced soliton blue-shift is transferred to the high harmonics, leading to a emission bands that are continuously tunable from 17 to 45 eV

    Supercontinuum generation in the vacuum ultraviolet through dispersive-wave and soliton-plasma interaction in noble-gas-filled hollow-core photonic crystal fiber

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    We report on the generation of a three-octave-wide supercontinuum extending from the vacuum ultraviolet (VUV) to the near-infrared, spanning at least 113 to 1000 nm (i.e., 11 to 1.2 eV), in He-filled hollow-core kagome-style photonic crystal fiber. Numerical simulations confirm that the main mechanism is a novel and previously undiscovered interaction between dispersive-wave emission and plasma-induced blueshifted soliton recompression around the fiber zero dispersion frequency. The VUV part of the supercontinuum, which modeling shows to be coherent and possess a simple phase structure, has sufficient bandwidth to support single-cycle pulses of 500 attosecond duration. We also demonstrate, in the same system, the generation of narrower-band VUV pulses, through dispersive-wave emission, tunable from 120 to 200 nm with efficiencies exceeding 1% and VUV pulse energies in excess of 50 nJ.Comment: 7 pages, 5 figure

    Mitochondria directly influence fertilisation outcome in the pig

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    The mitochondrion is explicitly involved in cytoplasmic regulation and is the cell's major generator of ATP. Our aim was to determine whether mitochondria alone could influence fertilisation outcome. In vitro, oocyte competence can be assessed through the presence of glucose-6-phosphate dehydrogenase (G6PD) as indicated by the dye, brilliant cresyl blue (BCB). Using porcine in vitro fertilisation (IVF), we have assessed oocyte maturation, cytoplasmic volume, fertilisation outcome, mitochondrial number as determined by mtDNA copy number, and whether mitochondria are uniformly distributed between blastomeres of each embryo. After staining with BCB, we observed a significant difference in cytoplasmic volume between BCB positive (BCB+) and BCB negative (BCB-) oocytes. There was also a significant difference in mtDNA copy number between fertilised and unfertilised oocytes and unequal mitochondrial segregation between blastomeres during early cleavage stages. Furthermore, we have supplemented BCB- oocytes with mitochondria from maternal relatives and observed a significant difference in fertilisation outcomes following both IVF and intracytoplasmic sperm injection (ICSI) between supplemented, sham-injected and non-treated BCB- oocytes. We have therefore demonstrated a relationship between oocyte maturity, cytoplasmic volume, and fertilisation outcome and mitochondrial content. These data suggest that mitochondrial number is important for fertilisation outcome and embryonic development. Furthermore, a mitochondrial pre-fertilisation threshold may ensure that, as mitochondria are diluted out during post-fertilisation cleavage, there are sufficient copies of mtDNA per blastomere to allow transmission of mtDNA to each cell of the post-implantation embryo after the initiation of mtDNA replication during the early postimplantation stages

    Managing and Partnering with External Stakeholders

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    The weakening of the traditional management hierarchy, the hollowing out of corporations, and an increasing management emphasis on boundarylessness have created a new mind set concerning external stakeholders. Increasingly, organizations are moving beyond traditional stakeholder management techniques to partnering tactics that lead to the achievement of common goals. In spite of these trends, there has been very little effort in the management literature to tie stakeholder management and partnering tactics. This article demonstrates how successful partnerships with stakeholders create such valued benefits as increased product success rates, increased manufacturing efficiency, the development of distinctive competencies arising from partnerships with local communities or government agencies, reduced unfavorable litigation, reduced levels of negative publicity, and favorable regulatory policies

    Influence of Decompression Rate on Hemodynamic Compensation to Continuous Lower Body Negative Pressure

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    We applied lower body negative pressure (LBNP) continuously, at three decompression rates, in an attempt to simulate uncontrolled hemorrhage as might be experienced by victims of traumatic injury. The purpose of our study was to determine whether hemodynamic compensations to simulated hemorrhage depend more on the magnitude, or the rate of change in pressure applied. Forty five (45) young, healthy subjects participated. We recorded the electrocardiogram, beat-to-beat arterial pressure (finger photoplethysmography), and measured cardiac output (inert gas rebreathing to calculate stroke volume) during continuous LBNP applied at three different decompression rates (n = 15 subjects for each rate; slow = 3 mm Hg∙min-1; medium = 6 mm Hg∙min-1; and fast = 12 mm Hg∙min-1) to an ending pressure of -60 mmHg. Slopes relating changes of dependent variable responses to the magnitude of decompression were calculated with linear regression, and group results were compared with ANOVA. LBNP increased (pooled across groups from 0 to -60 mmHg) heart rates (+28%; p ≤ .05 ), and decreased mean arterial pressures (-10%; p ≤ .05) and stroke volumes (-66%; p ≤ .05). The magnitude of changes induced by LBNP were not different between groups (p ≥ .4). Slopes (pooled across groups) relating heart rate (.3 bpm/mmHg ), mean arterial pressure (-.16 mmHg/mmHg), and stroke volume (-1.3 ml/mmHg) to the level of LBNP applied were not dependent on decompression rate (all ANOVA comparisons, p ≥ .3). We conclude that hemodynamic changes during continuous LBNP are associated directly with the magnitude of pressure applied, irrespective of the rate of decompression. Our results suggest that hemodynamic compensations to simulated uncontrolled hemorrhage are robust, and are not compromised by increasing the speed of decompression to simulate a greater rate of blood loss

    Algorithms for the Numerical Solution of a Finite-Part Integral Equation

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    The authors investigate a hypersingular integral equation which arises in the study of acoustic wave scattering by moving objects. A Galerkin method and two collocation methods are presented for solving the problem numerically. These numerical techniques are compared and contrasted in three test problems
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