Timeshare Owners’ Perceptions of and Preferred Ways of Participating in Tourism Planning

Purpose To explore the impact of prostate cancer treatment on: (a) the experience of symptoms (i.e. sexual, urinary, and bowel), and (b) perceived health state of men with prostate cancer one month following their radiation treatment. Methods A prospective pre-test–post-test descriptive survey was conducted on a convenience sample of 73 men with prostate cancer who were recruited from a Regional Cancer Centre in Southwestern Ontario, Canada. Participants receiving radiation treatment (brachy therapy, high dose radiation [HDR] and external beam radiation [EBR], or EBR alone) completed a questionnaire that elicited information pertaining to quality of life (QOL), symptom experiences, and perceived health state prior to, and one month after completion of their radiation treatment. Results Post-treatment scores showed increased problems with urinary bother (ppp=0.002) and function (p=0.001), and sexual function (p Discussion Our findings suggest that prostate cancer treatment presents a challenge with regard to symptom experiences and perceived health state in men with prostate cancer. Therefore, strategies for patient education to assist men to cope with their symptoms and to provide them with support in the initial weeks following treatment are discussed

Riemann-Hilbert problem for the small dispersion limit of the KdV equation and linear overdetermined systems of Euler-Poisson-Darboux type

We study the Cauchy problem for the Korteweg de Vries (KdV) equation with small dispersion and with monotonically increasing initial data using the Riemann-Hilbert (RH) approach. The solution of the Cauchy problem, in the zero dispersion limit, is obtained using the steepest descent method for oscillatory Riemann-Hilbert problems. The asymptotic solution is completely described by a scalar function \g that satisfies a scalar RH problem and a set of algebraic equations constrained by algebraic inequalities. The scalar function \g is equivalent to the solution of the Lax-Levermore maximization problem. The solution of the set of algebraic equations satisfies the Whitham equations. We show that the scalar function \g and the Lax-Levermore maximizer can be expressed as the solution of a linear overdetermined system of equations of Euler-Poisson-Darboux type. We also show that the set of algebraic equations and algebraic inequalities can be expressed in terms of the solution of a different set of linear overdetermined systems of equations of Euler-Poisson-Darboux type. Furthermore we show that the set of algebraic equations is equivalent to the classical solution of the Whitham equations expressed by the hodograph transformation.Comment: 32 pages, 1 figure, latex2

Exploring Hyperons and Hypernuclei with Lattice QCD

In this work we outline a program for lattice QCD that would provide a first step toward understanding the strong and weak interactions of strange baryons. The study of hypernuclear physics has provided a significant amount of information regarding the structure and weak decays of light nuclei containing one or two Lambda's, and Sigma's. From a theoretical standpoint, little is known about the hyperon-nucleon interaction, which is required input for systematic calculations of hypernuclear structure. Furthermore, the long-standing discrepancies in the P-wave amplitudes for nonleptonic hyperon decays remain to be understood, and their resolution is central to a better understanding of the weak decays of hypernuclei. We present a framework that utilizes Luscher's finite-volume techniques in lattice QCD to extract the scattering length and effective range for Lambda-N scattering in both QCD and partially-quenched QCD. The effective theory describing the nonleptonic decays of hyperons using isospin symmetry alone, appropriate for lattice calculations, is constructed.Comment: 24 pages, 7 figure

A role for Syk-kinase in the control of the binding cycle of the β2 integrins (CD11/CD18) in human polymorphonuclear neutrophils

A fine control of β2 integrin (CD11/CD18)-mediated firm adhesion of human neutrophils to the endothelial cell monolayer is required to allow ordered emigration. To elucidate the molecular mechanisms that control this process, intracellular protein tyrosine signaling subsequent to β2 integrin-mediated ligand binding was studied by immunoprecipitation and Western blotting techniques. The 72-kDa Syk-kinase, which was tyrosine-phosphorylated upon adhesion, was found to coprecipitate with CD18, the β-subunit of the β2 integrins. Moreover, inhibition of Syk-kinase by piceatannol enhanced adhesion and spreading but diminished N-formyl-Met-Leu-Phe-induced chemotactic migration. The enhancement of adhesiveness was associated with integrin clustering, which results in increased integrin avidity. In contrast, piceatannol had no effect on the surface expression or on the affinity of β2 integrins. Altogether, this suggests that Syk-kinase controls alternation of β2 integrin-mediated ligand binding with integrin detachment

Hyperon Nonleptonic Decays in Chiral Perturbation Theory Reexamined

We recalculate the leading nonanalytic contributions to the amplitudes for hyperon nonleptonic decays in chiral perturbation theory. Our results partially disagree with those calculated before, and include new terms previously omitted in the P-wave amplitudes. Although these modifications are numerically significant, they do not change the well-known fact that good agreement with experiment cannot be simultaneously achieved using one-loop S- and P-wave amplitudes.Comment: 14 pages, latex, 3 figures, uses axodraw.sty, minor additions, to appear in Phys. Rev.

Hyperons in Two Flavor Chiral Perturbation Theory

We use two-flavor chiral perturbation theory to describe hyperons. We focus on the strangeness conserving sector, and, as an example, calculate hyperon masses. Convergence of this two-flavor chiral expansion for observables is improved over the three-flavor theory. The cost, however, is a larger number of low-energy constants that must be ultimately determined from lattice QCD data. A formula for the mass of the omega baryon is derived to sixth order in this expansion, and will aid lattice practitioners in scale setting or tuning the strange quark mass.Comment: 14 pages, 3 figs, version published in PL

Chiral Perturbation Theory for |Delta I|=3/2 Hyperon Decays

We study the |Delta I|=3/2 amplitudes of hyperon non-leptonic decays of the form B->B'+pi in the context of chiral perturbation theory. The lowest-order predictions are determined in terms of only one unknown parameter and are consistent within errors with current data. We investigate the theoretical uncertainty of these predictions by calculating the leading non-analytic corrections. We also present an estimate for the size of the S-wave Lambda and Cascade decays which vanish at leading order. We find that the corrections to the lowest-order predictions are within the expectations of naive power counting and, therefore, that this picture can be tested more accurately with improved measurements.Comment: 22 pages, latex, 4 figures, uses axodraw.sty, few typos correcte

The Impact of Antiretroviral Therapy in a Cohort of HIV Infected Patients Going in and out of the San Francisco County Jail

BackgroundJails are an important venue of HIV care and a place for identification, treatment and referral for care. HIV infected inmates in the San Francisco County jail are offered antiretroviral treatment (ART), which many take only while in jail. We evaluated the effect of ART administration in a cohort of jail inmates going in and out of jail over a nine year period.Methodology/Principal FindingsIn this retrospective study, we examined inmates with HIV going in and out of jail. Inmates were categorized by patterns of ART use: continuous ART - ART both in and out of jail, [...] more likely to have higher VL than inmates on continuous ART. Furthermore, Inmates on intermittent ART and never-on ART lost 1.60; 95%CI (1.06, 2.13) and 1.97; 95%CI (0.96, 3.00) more CD4 cells per month, respectively, compared to continuously treated inmates. The continuous ART inmates gained 0.67CD4 cells/month.Conclusions/SignificanceContinuous ART therapy in jail inmate's benefits CD4 cell counts and control of VL especially compared to those who never took ART. Although jail inmates on intermittent ART were more likely to lose CD4 cells and experience higher VL over time than those on continuous ART, CD4 cell loss was slower in these inmates as compared to inmates never on ART. Further studies are needed to evaluate whether or not intermittent ART provides some benefit in outcome if continuous ART is not possible or likely

CP Violation in Hyperon Nonleptonic Decays within the Standard Model

We calculate the CP-violating asymmetries A(Lambda_-^0) and A(Xi_-^-) in nonleptonic hyperon decay within the Standard Model using the framework of heavy-baryon chiral perturbation theory (chiPT). We identify those terms that correspond to previous calculations and discover several errors in the existing literature. We present a new result for the lowest-order (in chiPT) contribution of the penguin operator to these asymmetries, as well as an estimate for the uncertainty of our result that is based on the calculation of the leading nonanalytic corrections.Comment: 21 pages, 2 figures; discussion clarified, results & conclusions unchanged, to appear in Phys. Rev.