Variabilidad espacial de los efectos socioeconómicos de las explotaciones de esquí alpino en los municipios rurales del Pirineo aragonés

22 páginas, 9 figuras, 4 tablas.[ES] Desde mediados del siglo XX se han impulsado las estaciones de esquí alpino en el Pirineo Aragonés, para incentivar las actividades turísticas y generar nuevas vías de desarrollo socio-económico. Transcurridos más de 30 años desde la construcción de las estaciones de esquí, cabe plantearse ¿en qué medida han contribuido a un desarrollo homogéneo en el territorio o han contribuido a desequilibrios espaciales? En este trabajo se estudian los efectos del turismo en la dinámica de la población (evolución del censo, cambios en la estructura demográfica y distribución de la población activa) y en el sector primario (evolución del número de explotaciones y de los censos ganaderos). Los resultados obtenidos en este trabajo permiten concluir que en el Pirineo Aragonés las estaciones de esquí afectan a un área espacial bastante reducida. En los municipios incluidos en ella se observan resultados positivos respecto a la evolución demográfica y negativos en el mantenimiento del sector primario. En los municipios no afectados por las estaciones de esquí, los resultados son totalmente diferentes, mostrando una evolución muy negativa de la población y positiva de los censos ganaderos[EN] Tourist activities, especially those related to skiing, have been promoted in the central Spanish Pyrenees since the 1950s. Using a 30-year dataset extending back to before the development of most ski resorts in the Pyrenees, we analysed the effects of ski resort development on the human population (change in the number of inhabitants, demographic structure and structure of the working sector) and the primary production activities of the area (number of farms and livestock). Spatial differences that have occurred in the socioeconomic changes since ski resort construction began are also analysed. Results show that the area influenced by ski resorts is restricted to the municipalities nearest to them. These municipalities show positive demographic changes and a negative evolution of primary activities. The municipalities more distant from the ski resorts show the opposite pattern. The advantages and problems of ski resort-based tourism in relation to the sustainable development of the Pyrenees are discussed in depth.[FR] Depuis la moitié du XXème siècle des nombreuses stations de ski alpin ont été créées dans les Pyrénées Aragonaises a fin de promouvoir les activités touristiques et de favoriser le développement socio-économique dans la région. Trente années sont passées depuis la construction des dernières stations de ski, et il faut se demander dans quelle mesure elles ont contribué à un développement homogène dans le territoire ou à des déséquilibres spatiaux. Dans ce travail on étudie les effets du tourisme sur la dynamique de la population (évolution de la population, changements de la structure démographique et de la distribution de la population active) ainsi que sur le secteur primaire (évolution du nombre d´exploitations et des effectifs de l’élevage). Les résultats obtenus dans ce travail permettent de conclure que dans les Pyrénées Aragonaises les stations de ski affectent des espaces assez réduits. On observe, dans les communes des zones affectées, des résultats positifs concernant l´évolution démographique, et négatifs quant au maintien du secteur primaire. Dans les communes qui ne sont pas affectées par les stations de ski les résultats sont très différents, avec une évolution très négative de la population et positive des effectifs animaux.Este trabajo se ha realizado con la ayuda de los proyectos: GGL2005- 04863/CLI, CGL2005-04508/BOS, financiados por la CICYT y FEDER, PIP098/2005 y PIP176/2005, financiados por el Gobierno de Aragón, y “Programa de grupos de investigación” (BOA 48 de 20-04-2005), también financiados por el Gobierno de Aragón.Peer reviewe

Comidas caseras y abatimiento a la obesidad: una revisión narrativa

La disminución en consumo de comidas típicas y el aumento en consumo de alimentos industrializados altos en grasa y azúcar coinciden con la prevalencia de obesidad. Se examinan las posibles ventajas sociales, sensoriales y somáticas de las comidas caseras y su relación con el peso corporal. Se realizó una búsqueda de literatura científica en cinco bases de datos, de 169 estudios localizados, 14 de ellos cumplieron los criterios de inclusión para una revisión narrativa. Los resultados muestran que las comidas caseras serían episodios de alimentación que incluyen platillos típicos aceptados por cultura en las familias y se ajustan a una dieta nutricionalmente adecuada. Un consumo regular de comidas caseras podría contribuir a disminuir la prevalencia de obesidad

Infección respiratoria aguda - IRA en el Departamento del Huila

En este documento con el fin de reconocer la importancia de las acciones de vigilancia y control epidemiológico en salud pública, se identifica la enfermedad de mayor incidencia en el departamento del Huila, con sus datos estadísticos de los últimos 10 años, descripción de la historia natural de esta enfermedad, además de los programas y estrategias implementadas por las instituciones encargadas de su control.In this document in order to recognize the importance of epidemiological surveillance and control actions in public health, identify the disease with the highest incidence in the department of Huila, with statistical data of the last 10 years, description of the natural history of this disease, in addition to the programs and strategies implemented by the institutions in charge of their control

Alterations in Circulating Monocytes Predict COVID-19 Severity and Include Chromatin Modifications Still Detectable Six Months after Recovery

This study was supported by the Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation (COVID-19 research call COV20/00181)—co-financed by the European Development Regional Fund “A way to achieve Europe” and by Consejería de Sanidad de la Comunidad de Madrid (CÍVICO study 2020/0082). R.L.G. and O.C.M. hold a research contract “Rio Hortega” (CM19/00120 and CM19/00092, respectively) from the Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation. MCL holds a predoctoral fellowship (FPU19/06393) from the Spanish Ministry of Science and Innovation.An early analysis of circulating monocytes may be critical for predicting COVID-19 course and its sequelae. In 131 untreated, acute COVID-19 patients at emergency room arrival, monocytes showed decreased surface molecule expression, including low HLA-DR, in association with an inflammatory cytokine status and limited anti-SARS-CoV-2-specific T cell response. Most of these alterations had normalized in post-COVID-19 patients 6 months after discharge. Acute COVID-19 monocytes transcriptome showed upregulation of anti-inflammatory tissue repair genes such as BCL6, AREG and IL-10 and increased accessibility of chromatin. Some of these transcriptomic and epigenetic features still remained in post-COVID-19 monocytes. Importantly, a poorer expression of surface molecules and low IRF1 gene transcription in circulating monocytes at admission defined a COVID-19 patient group with impaired SARS-CoV-2-specific T cell response and increased risk of requiring intensive care or dying. An early analysis of monocytes may be useful for COVID-19 patient stratification and for designing innate immunity-focused therapies.Depto. de MedicinaFac. de MedicinaTRUEUnión EuropeaMinisterio de Ciencia e Innovación (España)Comunidad de MadridInstituto de Salud Carlos IIIpu

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe

Dieta casera contra la obesidad

La alimentación es una necesidad inherente al ser humano, pero no siempre se hace de manera adequada. En México, la dieta tradicional ha venido disminuyendo por el aumento en el consumo de alimentos procesados no saludables que promueve sobrepeso y obesidad. Por lo cual se han promovido guías de alimentación saludable donde se recomienda el consumo de ciertos grupos de alimentos en ciertas proporciones. Las comidas caseras típicas consumidas cotidianamente en las proporciones adecuadas pueden ser nutritivas y promover un peso saludable, entre las ventajas está además que son facilitadas culturalmente pues son la cocina Mexicana que todos conocemos y disfrutamos

Do tourism-based ski resorts contribute to the homogeneous development of the Mediterranean mountains? A case study in the Central Spanish Pyrenees

14 páginas, 12 figuras, 3 tablas.Tourist activities, especially those related to skiing, have been promoted in the central Spanish Pyrenees since the 1950s. Using a 30-year data set extending back to before the development of most ski resorts in the Pyrenees, we analysed the effects of ski resort development on the human population (change in the number of inhabitants, demographic structure and structure of the working sector) and the primary production activities of the area (number of farms and livestock). Spatial differences that have occurred in the socioeconomic changes since ski resort construction began are also analysed. Results show that the area influenced by ski resorts is restricted to the municipalities nearest to them. These municipalities show positive demographic changes and a negative evolution of primary activities. The municipalities more distant from the ski resorts show the opposite pattern. The advantages and problems of ski resort-based tourism in relation to the sustainable development of the Pyrenees are discussed in depth.This work has been supported by the projects: GGL2005-04863/CLI, CGL2005-04508/BOS financed by the Spanish Comission of Science and Technology (CICYT) and FEDER, PIP098/2005 and PIP176/2005 financed by the Aragón Government, and ‘‘Programa de grupos de investigación consolidados’’ (BOA 48 of 20-04- 2005), also financed by the Aragón Government.Peer reviewe

Procedimiento para la recuperación de tántalo metal de condensadores electrolíticos

The subject matter of the present invention is a method for recovering tantalum metal from electrolytic capacitors. Said method includes several steps, mainly physical operations for extracting tantalum from the capacitors, with crushing of the dark material comprising tantalum metal and MnO2 and the conditions for reducing the latter compound to obtain tantalum metal being of particular importance. Said operations must not affect the tantalum present or introduce any metallic element into the reaction mixture. This ensures that the tantalum remains unchanged and is not contaminated with any additional component. [EN]Constituye el objeto de la presente invención un procedimiento para la recuperación de tántalo metal a partir de condensadores electrolíticos. El procedimiento incluye varias etapas, principalmente operaciones físicas para la extracción del tántalo de los condensadores, siendo especialmente importantes la trituración del material oscuro que comprende tántalo metal y MnO2 y las condiciones de reducción de este último compuesto para obtener el tántalo metal. Estas operaciones no deben afectar al tántalo existente ni aportar a la mezcla de reacción ningún elemento metálico. De esta manera se asegura que el tántalo permanece como tal y que no se impurifica con ningún componente adicional. [ES]Peer reviewedConsejo Superior de Investigaciones Científicas (España), WEEE International Recycling S.L.A1 Solicitud de patente con informe sobre el estado de la técnic