245 research outputs found

    Computer programs for the solution of systems of linear algebraic equations

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    FORTRAN subprograms for the solution of systems of linear algebraic equations are described, listed, and evaluated in this report. Procedures considered are direct solution, iteration, and matrix inversion. Both incore methods and those which utilize auxiliary data storage devices are considered. Some of the subroutines evaluated require the entire coefficient matrix to be in core, whereas others account for banding or sparceness of the system. General recommendations relative to equation solving are made, and on the basis of tests, specific subprograms are recommended

    ¿Qué otra cosa puede ser la infancia? : Deserciones desde un encuentro con la idea filosófica de infancia de Walter Kohan

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    ¿Qué otra cosa puede ser la infancia? Si la infancia se construye desde el lenguaje, correspondiéndole muchas acepciones, sin poder ser atrapada ni señalada con precisión ¿qué otras figuras de la infancia podemos encontrar en un ámbito educativo? ¿Qué otras representaciones podemos contraponer a lo que comúnmente se entiende por infancia: “primera etapa de la vida humana”? Más allá de esta imagen dominante ¿qué otras figuraciones se abren camino y nos habilitan a pensar de manera distinta y novedosa lo que creemos conocer sobre la infancia? La propuesta del presente trabajo consistirá en recorrer infantilmente un territorio de infancia, tomando como trampolín la idea filosófica de infancia de Walter Kohan. Una idea en movimiento, que se desplaza entre diálogos y encuentros. Una idea que nos afecta, invitándonos a re-pensar la infancia, más allá de una mirada cronológica, como interrupción, potencia y posibilidad (Kohan, 2007)Facultad de Humanidades y Ciencias de la Educació

    Mobile Emergency, an Emergency Support System for Hospitals in Mobile Devices: Pilot Study

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    BACKGROUND: Hospitals are vulnerable to natural disasters, man-made disasters, and mass causalities events. Within a short time, hospitals must provide care to large numbers of casualties in any damaged infrastructure, despite great personnel risk, inadequate communications, and limited resources. Communications are one of the most common challenges and drawbacks during in-hospital emergencies. Emergency difficulties in communicating with personnel and other agencies are mentioned in literature. At the moment of emergency inception and in the earliest emergency phases, the data regarding the true nature of the incidents are often inaccurate. The real needs and conditions are not yet clear, hospital personnel are neither efficiently coordinated nor informed on the real available resources. Information and communication technology solutions in health care turned out to have a great positive impact both on daily working practice and situations. OBJECTIVE: The objective of this paper was to find a solution that addresses the aspects of communicating among medical personnel, formalizing the modalities and protocols and the information to guide the medical personnel during emergency conditions with a support of a Central Station (command center) to cope with emergency management and best practice network to produce and distribute intelligent content made available in the mobile devices of the medical personnel. The aim was to reduce the time needed to react and to cope with emergency organization, while facilitating communications. METHODS: The solution has been realized by formalizing the scenarios, extracting, and identifying the requirements by using formal methods based on unified modeling language (UML). The system and was developed using mobile programming under iOS Apple and PHP: Hypertext Preprocessor My Structured Query Language (PHP MySQL). Formal questionnaires and time sheets were used for testing and validation, and a control group was used in order to estimate the reduction of time needed to cope with emergency cases. First, we have tested the usability and the functionalities of the solution proposed, then a real trial was performed to assess the reduction in communication time and the efficiency of the solution with respect to a case without Mobile Emergency tools. RESULTS: The solution was based on the development of a mobile emergency application and corresponding server device to cope with emergencies and facilitate all the related activities and communications, such as marking the position, contacting people, and recovering the exits information. The solution has been successfully tested within the Careggi Hospital, the largest medical infrastructure in Florence and Tuscany area in Italy, thus demonstrating the validity of the identified modalities, procedures, and the reduction in the time needed to cope with the emergency conditions. The trial was not registered as the test was conducted in realistic but simulated emergency conditions. CONCLUSIONS: By analyzing the requirements for developing a mobile app, and specifically the functionalities, codes, and design of the Mobile Emergency app, we have revealed the real advantages of using mobile emergency solutions compared to other more traditional solutions to effectively handle emergency situations in hospital settings

    Diagnostic Accuracy of Five Serologic Tests for Strongyloides stercoralis Infection

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    Background:The diagnosis of Strongyloides stercoralis (S. stercoralis) infection is hampered by the suboptimal sensitivity of fecal-based tests. Serological methods are believed to be more sensitive, although assessing their accuracy is difficult because of the lack of sensitivity of a fecal-based reference ("gold") standard.Methods:The sensitivity and specificity of 5 serologic tests for S. stercoralis (in-house IFAT, NIE-ELISA and NIE-LIPS and the commercially available Bordier-ELISA and IVD-ELISA) were assessed on 399 cryopreserved serum samples. Accuracy was measured using fecal results as the primary reference standard, but also using a composite reference standard (based on a combination of tests).Results:According to the latter standard, the most sensitive test was IFAT, with 94.6% sensitivity (91.2-96.9), followed by IVD-ELISA (92.3%, 87.7-96.9). The most specific test was NIE-LIPS, with specificity 99.6% (98.9-100), followed by IVD-ELISA (97.4%, 95.5-99.3). NIE-LIPS did not cross-react with any of the specimens from subjects with other parasitic infections. NIE-LIPS and the two commercial ELISAs approach 100% specificity at a cut off level that maintains ≥70% sensitivity.Conclusions:NIE-LIPS is the most accurate serologic test for the diagnosis of S. stercoralis infection. IFAT and each of the ELISA tests are sufficiently accurate, above a given cut off, for diagnosis, prevalence studies and inclusion in clinical trials.Fil: Bisoffi, Zeno. Sacro Cuore Hospital; ItaliaFil: Buonfrate, Dora. Sacro Cuore Hospital; ItaliaFil: Sequi, Marco. Istituto Di Ricerche Farmacologiche Mario Negri; ItaliaFil: Mejia, Rojelio. National Institute Of Allergy And Infectious Diseases; Estados UnidosFil: Cimino, Rubén Oscar. Universidad Nacional de Salta. Sede Regional Orán. Instituto de Investigación de Enfermedades Tropicales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Krolewiecki, Alejandro Javier. Universidad Nacional de Salta. Sede Regional Orán. Instituto de Investigación de Enfermedades Tropicales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Albonico, Marco. Sacro Cuore Hospital; ItaliaFil: Gobbo, Maria. Sacro Cuore Hospital; ItaliaFil: Bonafini, Stefania. Sacro Cuore Hospital; ItaliaFil: Angheben, Andrea. Sacro Cuore Hospital; ItaliaFil: Requena-Mendez, Ana. Universidad de Barcelona; EspañaFil: Muñoz, José. Universidad de Barcelona; EspañaFil: Nutman, Thomas B.. National Institute Of Allergy And Infectious Diseases; Estados Unido

    Wide intra- and inter-country variability in drug use and dosage in very-low-birth-weight newborns with severe infections

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    Purpose: To describe the use of ciprofloxacin and fluconazole for the treatment of sepsis in European neonatal intensive care units (NICUs) in order to better orient research aimed at acquiring essential knowledge in this critical area. Methods: The survey consisted of an online questionnaire for all participating NICUs on treatment schemes employed, rationales behind drug choices and interest in participation in research involving the two drugs. Results: A total of 189 level II and III NICUs participated in the survey, representing 25 countries, with Italy, UK and France providing the greatest number of centres (54% of total). Ciprofloxacin is used in 25% of NICUs that responded, although the indications for administering it vary between centres and the dosage ranges vary considerably, with 25% of NICUs giving ≤10 mg/kg/day and another 25 % giving ≥21 mg/kg/day. Factors given as affecting the decision to use ciprofloxacin are uncertainty about its safety and pharmacokinetics and level of penetration in the cerebrospinal fluid. Among the 70% of responding units that use fluconazole to treat fungal infection, 45% administer 6 mg/kg unit doses while 33% administer 12 mg/kg; 41% of NICUs use a 24-h interval between administrations while 20% wait 72h. Among the responding NICUs, 57% were willing to participate in a project on ciprofloxacin and 59% would consider participating in a randomized controlled trial evaluating fluconazole versus micafungin. Conclusions: Great variability in therapies exists within and between countries. Numerous centres are interested in participating in research on these drugs, highlighting the need for further knowledge on sepsis treatment and European centres’ interest in off-patent medicine research

    Les relacions socioeducatives i el reconeixement. Projeccions ètiques i morals de l'educació social des de la teoria d'Àxel Honneth

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    Premi UAB de la Fundació Autònoma Solidària (FAS) als millors Treballs de Fi de Grau sobre desenvolupament sostenible i justícia global. 3a Edició, curs 2018/2019Es porta a terme una recerca teòrica respecte les implicacions ètiques i morals de la teoria del reconeixement d'Axel Honneth per a la pràctica des i les professionals de a l'Educació Social. Mitjançant l'anàlisi documental i la recerca sistematitzada de literatura científica s'identifiquen els punts claus a tenir en compte així com les limitacions d'aquesta aportació. Els resultats mostren una alta polivalència de la teoria en quant als seus contextos d'aplicació i eficàcia a l'hora d'avaluar l'estat de les relacions socioeducatives sota la idea de justícia social. No obstant, la seva voluntat monista es discutida i s'identifiquen jerarquies entre les diferents esferes de reconeixement que generen possibles limitacions. Finalment es proposa una guia per l'actuació dels i les professionals que tingui en el reconeixement, a defensa de la dignitat i la justícia social els elements claus per a una relació ètica.Se lleva a cabo una investigación teórica con respecto a las implicaciones ético-morales de la teoría del reconocimiento de Axel Honneth para la práctica de los y las profesionales de la Educación Social. Mediante el análisis documental y la búsqueda sistematizada de literatura científica se identifican los puntos clave a tener en cuenta así como las limitaciones de esta aportación. Los resultados muestran una alta polivalencia de la teoría en cuanto a sus contextos de aplicación y eficacia a la hora de evaluar el estado de las relaciones socioeducativas bajo la idea de justicia social. No obstante, su voluntad monista es discutida y se identifican jerarquías entre las diferentes esferas de reconocimiento que generan posibles limitaciones. Finalmente se propone una guía para la actuación de los y las profesionales que tenga en el reconocimiento, la defensa de la dignidad y la justicia social los elementos clave para una relación ética.A theoretical investigation is carried out within the ethical-moral implications of Axel Honneth's recognition theory for the practice of Social Education professionals. Through the documentary analysis and the systematized search of scientific literature, the key points as well as the limitations of this contribution are identified. The results show a high polyvalence of the theory in terms of its contexts of application and effectiveness when evaluating the state of socio-educational relations under the idea of social justice. However, their monistic will is discussed and hierarchies are identified among the different spheres of recognition that generate possible limitations. Finally, a guide is proposed for the action of the professionals who have in the recognition, the defense of dignity and social justice the key elements for an ethical relationship

    Multi-layer spiral CT with 2D, 3D and 4D volume rendered electronic reconstructions of wax models and natural bone made by Giuseppe Astorri kept at “Luigi Cattaneo” Museum in Bologna

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    The Museum’s collection of normal and pathological wax anatomical models provides a clear understanding of the developments in medical knowledge that took place during the 18th and 19th centuries. In this period the interest of the anatomists began to move from normal anatomy to pathological anatomy. The wax modelers made both types of wax anatomical models: normal and pathological. Our study investigates through the works of Giuseppe Astorri the differences between these two types of models, revealing hidden structures and materials used in a completely non-invasive way. The Computer Tomography (CT) analysis was carried out using an experimental CT system specifically designed for the analysis of Cultural Heritage materials, developed by the X-ray imaging research group at the Physics and Astronomy Department of the University of Bologna. The results of this project can also be shown through a dynamic 3D (i.e. 4D) virtual projection using a device capable of emulating a holographic representation

    Diagnostic accuracy of five serologic tests for Strongyloides stercoralis infection.

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    Background: The diagnosis of Strongyloides stercoralis (S. stercoralis) infection is hampered by the suboptimal sensitivity of fecal-based tests. Serological methods are believed to be more sensitive, although assessing their accuracy is difficult because of the lack of sensitivity of a fecal-based reference ('gold') standard. Methods: The sensitivity and specificity of 5 serologic tests for S. stercoralis (in-house IFAT, NIE-ELISA and NIE-LIPS and the commercially available Bordier-ELISA and IVD-ELISA) were assessed on 399 cryopreserved serum samples. Accuracy was measured using fecal results as the primary reference standard, but also using a composite reference standard (based on a combination of tests). Results: According to the latter standard, the most sensitive test was IFAT, with 94.6% sensitivity (91.2-96.9), followed by IVD-ELISA (92.3%, 87.7-96.9). The most specific test was NIE-LIPS, with specificity 99.6% (98.9-100), followed by IVD-ELISA (97.4%, 95.5-99.3). NIE-LIPS did not cross-react with any of the specimens from subjects with other parasitic infections. NIE-LIPS and the two commercial ELISAs approach 100% specificity at a cut off level that maintains ≥70% sensitivity. Conclusions: NIE-LIPS is the most accurate serologic test for the diagnosis of S. stercoralis infection. IFAT and each of the ELISA tests are sufficiently accurate, above a given cut off, for diagnosis, prevalence studies and inclusion in clinical trials
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