349 research outputs found
The stochastic gravitational wave background from turbulence and magnetic fields generated by a first-order phase transition
We analytically derive the spectrum of gravitational waves due to
magneto-hydrodynamical turbulence generated by bubble collisions in a
first-order phase transition. In contrast to previous studies, we take into
account the fact that turbulence and magnetic fields act as sources of
gravitational waves for many Hubble times after the phase transition is
completed. This modifies the gravitational wave spectrum at large scales. We
also model the initial stirring phase preceding the Kolmogorov cascade, while
earlier works assume that the Kolmogorov spectrum sets in instantaneously. The
continuity in time of the source is relevant for a correct determination of the
peak position of the gravitational wave spectrum. We discuss how the results
depend on assumptions about the unequal-time correlation of the source and
motivate a realistic choice for it. Our treatment gives a similar peak
frequency as previous analyses but the amplitude of the signal is reduced due
to the use of a more realistic power spectrum for the magneto-hydrodynamical
turbulence. For a strongly first-order electroweak phase transition, the signal
is observable with the space interferometer LISA.Comment: 46 pages, 17 figures. Replaced with revised version accepted for
publication in JCA
A Super-Oxidized Radical Cationic Icosahedral Boron Cluster
While the icosahedral closo-[BââHââ]²❠cluster does not display reversible electrochemical behavior, perfunctionalization of this species via substitution of all 12 BâH vertices with alkoxy or benzyloxy (OR) substituents engenders reversible redox chemistry, providing access to clusters in the dianionic, monoanionic, and neutral forms. Here, we evaluated the electrochemical behavior of the electron-rich Bââ(O-3-methylbutyl)ââ (1) cluster and discovered that a new reversible redox event that gives rise to a fourth electronic state is accessible through one-electron oxidation of the neutral species. Chemical oxidation of 1 with [N(2,4-BrâCâHâ)â]¡⺠afforded the isolable [1]¡⺠cluster, which is the first example of an open-shell cationic Bââ cluster in which the unpaired electron is proposed to be delocalized throughout the boron cluster core. The oxidation of 1 is also chemically reversible, where treatment of [1]¡⺠with ferrocene resulted in its reduction back to 1. The identity of [1]¡⺠is supported by EPR, UVâvis, multinuclear NMR (šH, ššB), and X-ray photoelectron spectroscopic characterization
A Super-Oxidized Radical Cationic Icosahedral Boron Cluster
While the icosahedral closo-[BââHââ]²❠cluster does not display reversible electrochemical behavior, perfunctionalization of this species via substitution of all 12 BâH vertices with alkoxy or benzyloxy (OR) substituents engenders reversible redox chemistry, providing access to clusters in the dianionic, monoanionic, and neutral forms. Here, we evaluated the electrochemical behavior of the electron-rich Bââ(O-3-methylbutyl)ââ (1) cluster and discovered that a new reversible redox event that gives rise to a fourth electronic state is accessible through one-electron oxidation of the neutral species. Chemical oxidation of 1 with [N(2,4-BrâCâHâ)â]¡⺠afforded the isolable [1]¡⺠cluster, which is the first example of an open-shell cationic Bââ cluster in which the unpaired electron is proposed to be delocalized throughout the boron cluster core. The oxidation of 1 is also chemically reversible, where treatment of [1]¡⺠with ferrocene resulted in its reduction back to 1. The identity of [1]¡⺠is supported by EPR, UVâvis, multinuclear NMR (šH, ššB), and X-ray photoelectron spectroscopic characterization
An Innovative Antenna Array with High Inter Element Isolation for Sub-6 GHz 5G MIMO Communication Systems
A novel technique is shown to improve the isolation between radiators in antenna arrays. The proposed technique suppresses the surface-wave propagation and reduces substrate loss thereby enhancing the overall performance of the array. This is achieved without affecting the antennaâs footprint. The proposed approach is demonstrated on a four-element array for 5G MIMO applications. Each radiating element in the array is constituted from a 3Ă3 matrix of interconnected resonant elements. The technique involves (i) incorporating matching stubs within the resonant elements, (ii) framing each of the four-radiating elements inside a dot-wall, and (iii) defecting the ground plane with dielectric slots that are aligned under the dot-walls. Results show that with the proposed approach the impedance bandwidth of the array is increased by 58.82% and the improvement in the average isolation between antennas #1&2, #1&3, #1&4 are 8 dB, 14 dB, 16 dB, and 13 dB, respectively. Moreover, improvement in the antenna gain is 4.2% and the total radiation efficiency is 23.53%. These results confirm the efficacy of the technique. The agreement between the simulated and measured results is excellent. Furthermore, the manufacture of the antenna array using the proposed approach is relatively straightforward and cost effective
Reassessing the Fighting Performance of Conscript Soldiers During the Malvinas/Falklands War (1982)
While the idea is controversial, it is quite possible that, at least under certain circumstances, the fighting effectiveness of a conscript army can equal that of a professional army. For any army, fighting effectiveness is not only influenced by the degree of psychological cohesion among soldiers and officers, but also by the organizational culture of each particular service unit towards the preparation for war and the waging of the conflict itself. The Malvinas (Falklands) War of 1982 demonstrates this very well. In this war, two different types of armies confronted one another: the British army, a professional and all volunteer force, and the Argentine army constituted principally of conscripted soldiers. In this regard, some analysts assert that the British concept was vindicated when a force of British professional soldiers defeated an opposing Argentine force of draftees twice as numerous. Analysts in general have rated the capabilities of the Argentine land forces as poor, although there were exceptions and some units performed very well. These cases deserve to be studied. Notably, the most effective Argentine effort came from some small Army units and one Navy unit, the 5th Marine Battalion. For these units, two primary reasons account for the differences in fighting performance. First, small Army groups fought well because there was cohesion among their components, conscripts, noncommissioned officers, and junior officers, especially by the attitude of the latter. Secondly, in the case of the Marine battalion, its performance was the product not only of good training, but also of the different institutional approach to waging war that the Argentine Navy employed. These, in turn, improved cohesion. By focusing upon these units and their effectiveness, a rather new picture of the Malvinas War comes to light that differs quite substantially from those drawn in the immediate aftermath of the war itself. It should also make us rethink the lessons of the war, including those that surround the professionals versus conscripts controversy
Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency
The contribution of B cells to the pathology of Omenn syndrome and leaky severe combined immunodeficiency (SCID) has not been previously investigated. We have studied a mut/mut mouse model of leaky SCID with a homozygous Rag1 S723C mutation that impairs, but does not abrogate, V(D)J recombination activity. In spite of a severe block at the proâB cell stage and profound B cell lymphopenia, significant serum levels of immunoglobulin (Ig) G, IgM, IgA, and IgE and a high proportion of Ig-secreting cells were detected in mut/mut mice. Antibody responses to trinitrophenyl (TNP)-Ficoll and production of high-affinity antibodies to TNPâkeyhole limpet hemocyanin were severely impaired, even after adoptive transfer of wild-type CD4+ T cells. Mut/mut mice produced high amounts of low-affinity self-reactive antibodies and showed significant lymphocytic infiltrates in peripheral tissues. Autoantibody production was associated with impaired receptor editing and increased serum B cellâactivating factor (BAFF) concentrations. Autoantibodies and elevated BAFF levels were also identified in patients with Omenn syndrome and leaky SCID as a result of hypomorphic RAG mutations. These data indicate that the stochastic generation of an autoreactive B cell repertoire, which is associated with defects in central and peripheral checkpoints of B cell tolerance, is an important, previously unrecognized, aspect of immunodeficiencies associated with hypomorphic RAG mutations
Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency
-linked severe combined immunodeficiency (SCID-X1) is a profound deficiency of T, B, and natural killer (NK) cell immunity caused by mutations in IL2RG encoding the common chain (Îłc) of several interleukin receptors. Gamma-retroviral (ÎłRV) gene therapy of SCID-X1 infants without conditioning restores T cell immunity without B or NK cell correction, but similar treatment fails in older SCID-X1 children. We used a lentiviral gene therapy approach to treat five SCID-X1 patients with persistent immune dysfunction despite haploidentical hematopoietic stem cell (HSC) transplant in infancy. Follow-up data from two older patients demonstrate that lentiviral vector Îłc transduced autologous HSC gene therapy after nonmyeloablative busulfan conditioning achieves selective expansion of gene-marked T, NK, and B cells, which is associated with sustained restoration of humoral responses to immunization and clinical improvement at 2 to 3 years after treatment. Similar gene marking levels have been achieved in three younger patients, albeit with only 6 to 9 months of follow-up. Lentiviral gene therapy with reduced-intensity conditioning appears safe and can restore humoral immune function to posthaploidentical transplant older patients with SCID-X1
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