258 research outputs found

    Mechanisms affecting the overturning response in global warming simulations

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    Climate models used to produce global warming scenarios exhibit widely diverging responses of the thermohaline circulation (THC). To investigate the mechanisms responsible for this variability, a regional Atlantic Ocean model driven with forcing diagnosed from two coupled greenhouse gas simulations has been employed. One of the coupled models (MPI) shows an almost constant THC, the other (GFDL) shows a declining THC in the twenty-first century. The THC evolution in the regional model corresponds rather closely to that of the respective coupled simulation, that is, it remains constant when driven with the forcing from the MPI model, and declines when driven with the GFDL forcing. These findings indicate that a detailed representation of ocean processes in the region covered by the Atlantic model may not be critical for the simulation of the overall THC changes in a global warming scenario, and specifically that the coupled model’s rather coarse representation of water mass formation processes in the subpolar North Atlantic is unlikely to be the primary cause for the large differences in the THC evolution. Sensitivity experiments have confirmed that a main parameter governing the THC response to global warming is the density of the intermediate waters in the Greenland–Iceland–Norwegian Seas, which in turn influences the density of the North Atlantic Deep Water, whereas changes in the air–sea heat and freshwater fluxes over the subpolar North Atlantic are only of moderate importance, and mainly influence the interannual–decadal variability of THC. Finally, as a consequence of changing surface fluxes, the Labrador Sea convection ceases by about 2030 under both forcings (i.e., even in a situation where the overall THC is stable) indicating that the eventual breakdown of the convection is likely but need not coincide with substantial THC changes

    Pharmacologic treatment of gastroparesis: What is (still) on the horizon?

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    Gastroparesis is a neuromuscular disorder of the upper gastrointestinal tract. Patients typically complain about early satiety, postprandial fullness, nausea and vomiting. Etiology is multifactorial. Treatment strategies include nutritional support, pharmacologic agents or surgery for refractory cases. Metoclopramide is the first and only FDA approved pharmacologic agent for (diabetic) Gastroparesis. A couple of compounds are currently in clinical testing. Some beacons of hope have failed recently, however. Here we present an update on possible future treatment options

    The North Atlantic in the greenhouse - overturning response and sensitivities

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    The response of the thermohaline circulation (THC) in climate models on global warming scenarios differs fundamentally. To examine the role of the ocean component for this deviating behaviour,diagnosed fluxes from coupled greenhouse gas simulations are used to drive a regional model of the Atlantic Ocean. The results demonstrate, that the general response of the THC due to changes in atmospheric forcing is quite robust and insensitive to the improved representation of the ocean component. In order to test the crucial mechanisms for the evolution of the meridional overturning, sensitivity studies are by focussing on different combinations of surface fluxes are performed. The response indicates that the density in the Nordic Seas and subsequently the overflow waters determine trends and long-term variability of the overturning circulation, underlining the importance of that region for the THC. Deep water formation within the Labrador Sea, responsible for interannual to decadal variability is quite sensitive to anthropogenic changes in the surface fluxes, so that its convection eventually breaks down under surface warming and freshening

    Do all dike instabilities cause flooding?

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    One of the failure mechanisms of dikes is slope instability at the landward side. Often, one instability does not lead to flooding, and several successive instabilities are needed before the dike overtops, and erosion and breaching can occur, especially at lower water levels. In this paper we propose a method to estimate the probability of flooding, taking into account the residual resistance against flooding after the first instability. We base ourselves on basic probabilistic techniques and common slope stability analyses and estimate the probability of flooding by calculating the probability of several successive (conditional) instabilities. Because the geotechnical failure and dike failure is not the same for each water level, we evaluate the probability for different water levels. The case example shows that there is a considerable margin between the probability of geotechnical failure and the probability of flooding, especially at relatively low water levels. It also shows that the current practice of assuming that the probability of flooding is equal to the probability of instability is very conservative.This work is part of the research programme All-Risk with project number P15-21, which is (partly) financed by NWO Domain Applied and Engineering Sciences. Deltares is also gratefully acknowledged for supporting this research

    Influence of contingency awareness on neural, electrodermal and evaluative responses during fear conditioning

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    In an fMRI study, effects of contingency awareness on conditioned responses were assessed in three groups comprising 118 subjects. A differential fear-conditioning paradigm with visual conditioned stimuli, an electrical unconditioned stimulus and two distractors was applied. The instructed aware group was informed about the contingencies, whereas the distractors prevented contingency detection in the unaware group. The third group (learned aware) was not informed about the contingencies, but learned them despite the distractors. Main effects of contingency awareness on conditioned responses emerged in several brain structures. Post hoc tests revealed differential dorsal anterior cingulate, insula and ventral striatum responses in aware conditioning only, whereas the amygdala was activated independent of contingency awareness. Differential responses of the hippocampus were specifically observed in learned aware subjects, indicating a role in the development of contingency awareness. The orbitofrontal cortex showed varying response patterns: lateral structures showed higher responses in instructed aware than unaware subjects, the opposite was true for medial parts. Conditioned subjective and electrodermal responses emerged only in the two aware groups. These results confirm the independence of conditioned amygdala responses from contingency awareness and indicate specific neural circuits for different aspects of fear acquisition in unaware, learned aware and instructed aware subjects

    Validation of flood risk models: Current practice and possible improvements

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    [EN] Although often neglected, model validation is a key topic in flood risk analysis, as flood risk estimates are used to underpin large investments and important decisions. In this paper, we discuss the state of the art of flood risk model validation, using as input the discussion among more than 50 experts at two scientific workshop events. The events aimed at identifying policy and research recommendations towards promoting more common practice of validation, and an improvement of flood risk model reliability. We pay specific attention to different components of the risk modelling chain (i.e. flood hazard, defence failure, and flood damage analysis) as well as to their role in risk estimates, to highlight specificities and commonalities with respect to implemented techniques and research needs. The main conclusions from this analysis can be summarised as the need of higher quality data to perform validation and of benchmark solutions to be followed in different contexts, along with a greater involvement of end-users in the application on flood risk model validation.The authors acknowledge with gratitude all the participants and the speakers at the workshop in Delft (December 2014) and at the special session at FloodRisk2016 (October 2016); as the main content of the papers was derived from the information presented and the fruitful discussions at these two events. As such, it may include subjective considerations by the authors and may not reflect the individual statements presented at these events. We also acknowledge the EuropeaBallio et an Geoscience Union (EGU), the Panta Rhei Initiative, the FloodRisk2016 Scientific Committee, and Deltares for supporting these events.Molinari, D.; De Bruijn, KM.; Castillo-RodrĂ­guez, J.; Aronica, GT.; Bouwer, LM. (2019). Validation of flood risk models: Current practice and possible improvements. International Journal of Disaster Risk Reduction. 33:441-448. https://doi.org/10.1016/j.ijdrr.2018.10.022S4414483

    The role of salinity in the decadal variability of the North Atlantic meridional overturning circulation

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    Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Climate Dynamics 33 (2009): 777-793, doi:10.1007/s00382-008-0523-2.An OGCM hindcast is used to investigate the linkages between North Atlantic Ocean salinity and circulation changes during 1963–2003. The focus is on the eastern subpolar region consisting of the Irminger Sea and the eastern North Atlantic where a careful assessment shows that the simulated interannual to decadal salinity changes in the upper 1500 m reproduce well those derived from the available record of hydrographic measurements. In the model, the variability of the Atlantic meridional overturning circulation (MOC) is primarily driven by changes in deep water formation taking place in the Irminger Sea and, to a lesser extent, the Labrador Sea. Both are strongly influenced by the North Atlantic Oscillation (NAO). The modeled interannual to decadal salinity changes in the subpolar basins are mostly controlled by circulation-driven anomalies of freshwater flux convergence, although surface salinity restoring to climatology and other boundary fluxes each account for approximately 25% of the variance. The NAO plays an important role: a positive NAO phase is associated with increased precipitation, reduced northward salt transport by the wind-driven intergyre gyre, and increased southward flows of freshwater across the Greenland-Scotland ridge. Since the NAO largely controlled deep convection in the subpolar gyre, fresher waters are found near the sinking region during convective events. This markedly differs from the active influence on the MOC that salinity exerts at decadal and longer timescales in most coupled models. The intensification of the MOC that follows a positive NAO phase by about 2 years does not lead to an increase in the northward salt transport into the subpolar domain at low frequencies because it is cancelled by the concomitant intensification of the subpolar gyre which shifts the subpolar front eastward and reduces the northward salt transport by the North Atlantic Current waters. This differs again from most coupled models, where the gyre intensification precedes that of the MOC by several years.Support from NSF Grant 82677800 with the Woods Hole Oceanographic Institution, and (to CF) from the Institut universitaire de France and European FP6 project DYNAMITE (contract 003903-GOCE) and (to JD) from the NOAA Office of Hydrologic Development through a scientific appointment administered by UCAR is gratefully acknowledged
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