111 research outputs found
Families, Nations, and Strangers
This is the text of The Lindley Lecture for 1994, given by Samuel Scheffler, an American philosopher
Why practice philosophy as a way of life?
This essay explains why there are good reasons to practice philosophy as a way of life. The argument begins with the assumption that we should live well but that our understanding of how to live well can be mistaken. Philosophical reason and reflection can help correct these mistakes. Nonetheless, the evidence suggests that philosophical reasoning often fails to change our dispositions and behavior. Drawing on the work of Pierre Hadot, the essay claims that spiritual exercises and communal engagement mitigate the factors that prevent us from living in accord- ance with our conceptions of the good life. So, many of us have reasons to engage in philosophical reasoning along with behavioral, cognitive, and social strategies to alter our behavior and attitudes so that they’re in line with our philosophical commitments. In these respects, many of us should practice philosophy as a way of life
Pretraining is All You Need: A Multi-Atlas Enhanced Transformer Framework for Autism Spectrum Disorder Classification
Autism spectrum disorder (ASD) is a prevalent psychiatric condition
characterized by atypical cognitive, emotional, and social patterns. Timely and
accurate diagnosis is crucial for effective interventions and improved outcomes
in individuals with ASD. In this study, we propose a novel Multi-Atlas Enhanced
Transformer framework, METAFormer, ASD classification. Our framework utilizes
resting-state functional magnetic resonance imaging data from the ABIDE I
dataset, comprising 406 ASD and 476 typical control (TC) subjects. METAFormer
employs a multi-atlas approach, where flattened connectivity matrices from the
AAL, CC200, and DOS160 atlases serve as input to the transformer encoder.
Notably, we demonstrate that self-supervised pretraining, involving the
reconstruction of masked values from the input, significantly enhances
classification performance without the need for additional or separate training
data. Through stratified cross-validation, we evaluate the proposed framework
and show that it surpasses state-of-the-art performance on the ABIDE I dataset,
with an average accuracy of 83.7% and an AUC-score of 0.832. The code for our
framework is available at https://github.com/Lugges991/METAForme
A High-performance, Energy-efficient Modular DMA Engine Architecture
Data transfers are essential in today's computing systems as latency and
complex memory access patterns are increasingly challenging to manage. Direct
memory access engines (DMAEs) are critically needed to transfer data
independently of the processing elements, hiding latency and achieving high
throughput even for complex access patterns to high-latency memory. With the
prevalence of heterogeneous systems, DMAEs must operate efficiently in
increasingly diverse environments. This work proposes a modular and highly
configurable open-source DMAE architecture called intelligent DMA (iDMA), split
into three parts that can be composed and customized independently. The
front-end implements the control plane binding to the surrounding system. The
mid-end accelerates complex data transfer patterns such as multi-dimensional
transfers, scattering, or gathering. The back-end interfaces with the on-chip
communication fabric (data plane). We assess the efficiency of iDMA in various
instantiations: In high-performance systems, we achieve speedups of up to 15.8x
with only 1 % additional area compared to a base system without a DMAE. We
achieve an area reduction of 10 % while improving ML inference performance by
23 % in ultra-low-energy edge AI systems over an existing DMAE solution. We
provide area, timing, latency, and performance characterization to guide its
instantiation in various systems.Comment: 14 pages, 14 figures, accepted by an IEEE journal for publicatio
Distribution and Emergency
Streaming video requires RealPlayer to view.The University Archives has determined that this item is of continuing value to OSU's history.Humanitarian organizations divide their work into
two categories: development aid that improves underlying
conditions, and emergency aid, given in response to a natural or
manmade disaster. However, Jennifer Rubenstein, a fellow at
Princeton University, questioned this distinction. While it might
have logistical advantages, she argued, it does not suit the
variety of situations and populations requiring aid.Ohio State University. Mershon Center for International Security StudiesEvent webpage, streaming video, photos, power point presentation, and lecture summar
Stunting as a Synonym of Social Disadvantage and Poor Parental Education
Socially, economically, politically and emotionally (SEPE) disadvantaged children are shorter than children from affluent background. In view of previous work on the lack of association between nutrition and child growth, we performed a study in urban schoolchildren. We measured 723 children (5.83 to 13.83 years); Kupang, Indonesia; three schools with different social background. We investigated anthropometric data, clinical signs of malnutrition, physical fitness, parental education, and household equipment. Subjective self-confidence was assessed by the MacArthur test. The prevalence of stunting was between 8.5% and 46.8%. Clinical signs of under- or malnutrition were absent even in the most underprivileged children. There was no delay in tooth eruption. Underprivileged children are physically fitter than the wealthy. The correlation between height and state of nutrition (BMI_SDS, skinfold_SDS, MUAC_SDS) ranged between r = 0.69 (p < 0.01) and r = 0.43 (p < 0.01) in private school children, and between r = 0.07 (ns) and r = 0.32 (p < 0.01) in the underprivileged children. Maternal education interacted with height in affluent (r = 0.20, p < 0.01) and in underprivileged children (r = 0.20, p < 0.01). The shortness of SEPE disadvantaged children was not associated with anthropometric and clinical signs of malnutrition, nor with delay in physical development. Stunting is a complex phenomenon and may be considered a synonym of social disadvantage and poor parental education
Functional quantitative susceptibility mapping (fQSM)
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is a powerful technique, typically based on the statistical analysis of the magnitude component of the complex time-series. Here, we additionally interrogated the phase data of the fMRI time-series and used quantitative susceptibility mapping (QSM) in order to investigate the potential of functional QSM (fQSM) relative to standard magnitude BOLD fMRI. High spatial resolution data (1 mm isotropic) were acquired every 3 seconds using zoomed multi-slice gradient-echo EPI collected at 7 T in single orientation (SO) and multiple orientation (MO) experiments, the latter involving 4 repetitions with the subject's head rotated relative to B0. Statistical parametric maps (SPM) were reconstructed for magnitude, phase and QSM time-series and each was subjected to detailed analysis. Several fQSM pipelines were evaluated and compared based on the relative number of voxels that were coincidentally found to be significant in QSM and magnitude SPMs (common voxels). We found that sensitivity and spatial reliability of fQSM relative to the magnitude data depended strongly on the arbitrary significance threshold defining “activated” voxels in SPMs, and on the efficiency of spatio-temporal filtering of the phase time-series. Sensitivity and spatial reliability depended slightly on whether MO or SO fQSM was performed and on the QSM calculation approach used for SO data. Our results present the potential of fQSM as a quantitative method of mapping BOLD changes. We also critically discuss the technical challenges and issues linked to this intriguing new technique
The three-prong method: a novel assessment of residual stress in laser powder bed fusion
<p><b>Boxplots of quantitative parameters</b> included <b>a)</b> ratio of N-acetylaspartate and N-acetylaspartylglutamate (NAA) to creatine and phosphocreatine (Cr) both for chemical shift imaging (CSI) and single voxel (SV) measurements, <b>b)</b> ratio of choline containing compounds (Cho) to Cr both for CSI and SV, <b>c)</b> myelin water fraction (MWF), <b>d)</b> magnetization transfer ratio (MTR), <b>e)</b> quantitative susceptibility mapping (QSM), and <b>f)</b> R2*. Parameters were measured in frontal white matter (WM) and two parameters within the cortico-spinal tract (CST): at the level of the posterior limb of internal capsule (PLIC) and at the level of the centrum semiovale (CS), see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167274#pone.0167274.g001" target="_blank">Fig 1</a>.</p
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