Systematic Review and Regression Modeling of the Effects of Age, Body Size, and Exercise on Cardiovascular Parameters in Healthy Adults

Purpose Blood pressure, cardiac output, and ventricular volumes correlate to various subject features such as age, body size, and exercise intensity. The purpose of this study is to quantify this correlation through regression modeling. Methods We conducted a systematic review to compile reference data of healthy subjects for several cardiovascular parameters and subject features. Regression algorithms used these aggregate data to formulate predictive models for the outputs—systolic and diastolic blood pressure, ventricular volumes, cardiac output, and heart rate—against the features—age, height, weight, and exercise intensity. A simulation-based procedure generated data of virtual subjects to test whether these regression models built using aggregate data can perform well for subject-level predictions and to provide an estimate for the expected error. The blood pressure and heart rate models were also validated using real-world subject-level data. Results The direction of trends between model outputs and the input subject features in our study agree with those in current literature. Conclusion Although other studies observe exponential predictor-output relations, the linear regression algorithms performed the best for the data in this study. The use of subject-level data and more predictors may provide regression models with higher fidelity. Significance Models developed in this study can be useful to clinicians for personalized patient assessment and to researchers for tuning computational models

Classifying Optical (Out)bursts in Cataclysmic Variables: The Distinct Observational Characteristics of Dwarf Novae, Micronovae, Stellar Flares, and Magnetic Gating

Cataclysmic variables can experience short optical brightenings, which are commonly attributed to phenomena such as dwarf novae outbursts, micronovae, donor flares, or magnetic gating bursts. Since these events exhibit similar observational characteristics, their identification has often been ambiguous. In particular, magnetic gating bursts and micronovae have been suggested as alternative interpretations of the same phenomena. Here we show that the timescales and energies separate the optical brightenings into separate clusters consistent with their different classifications. This suggests that micronovae and magnetic gating bursts are in fact separate phenomena. Based on our findings, we develop diagnostic diagrams that can distinguish between these bursts/flares based on their properties. We demonstrate the effectiveness of this approach on observations of a newly identified intermediate polar, CTCV J0333-4451, which we classify as a magnetic gating system. CTCV J0333-4451 is the third highest spin-to-orbital period ratio intermediate polar with magnetic gating, suggesting that these bursts are common among these rare systems

SDSS J134441.83+204408.3: A Highly Asynchronous Short-period Magnetic Cataclysmic Variable with a 56 MG Field Strength

When the accreting white dwarf in a magnetic cataclysmic variable star (mCV) has a field strength in excess of 10 MG, it is expected to synchronize its rotational frequency to the binary orbit frequency, particularly at small binary separations, due to the steep radial dependence of the magnetic field. We report the discovery of an mCV (SDSS J134441.83+204408.3, hereafter J1344) that defies this expectation by displaying asynchronous rotation (Pspin/Porb = 0.893) in spite of a high surface field strength (B = 56 MG) and a short orbital period (114 minutes). Previously misidentified as a synchronously rotating mCV, J1344 was observed by Transiting Exoplanet Survey Satellite during sector 50, and the resulting power spectrum shows distinct spin and orbital frequencies, along with various sidebands and harmonics. Although there are several other asynchronous mCVs at short orbital periods, the presence of cyclotron humps in J1344's Sloan Digital Sky Survey spectrum makes it possible to directly measure the field strength in the cyclotron-emitting region, and while a previously study estimated 65 MG based on its identification of two cyclotron humps, we revise this to 56 ± 2 MG based on the detection of a third hump and on our modeling of the cyclotron spectrum. Short-period mCVs with field strengths above 10 MG are normally expected to be synchronous, so the highly asynchronous rotation in J1344 presents an interesting challenge for theoretical studies of spin-period evolution

Astro2020 APC White Paper. 2020 Vision: Towards a Sustainable OIR System

Open-access telescopes of all apertures are needed to operate a competitive and efficient national science program. While larger facilities contribute light-gathering power and angular resolution, smaller ones dominate for field of view, time-resolution, and especially, total available observing time, thereby enabling our entire, diversely-expert community. Smaller aperture telescopes therefore play a critical and indispensable role in advancing science. Thus, the divestment of NSF support for modest-aperture (1 – 4 m) public telescopes poses a serious threat to U.S. scientific leadership, which is compounded by the unknown consequences of the shift from observations driven by individual investigators to survey-driven science. Given the much higher cost efficiency and dramatic science returns for investments in modest aperture telescopes, it is hard to justify funding only the most expensive facilities. We therefore urge the Astro2020 panel to explicitly make the case for modest aperture facilities, and to recommend enhancing this funding stream to support and grow this critical component of the OIR System. Further study is urgently needed to prioritize the numerous exciting potential capabilities of smaller facilities,and to establish sustainable, long-term planning for the System

A Magnetic Valve at L1 Revealed in TESS Photometry of the Asynchronous Polar BY Cam

We present TESS photometry of the asynchronous polar BY Cam, which undergoes a beat cycle between the 199.384 min white dwarf (WD) spin period and the 201.244 min orbital period. This results in changes in the flow of matter onto the WD. The TESS light curve covers 92% of the beat cycle once and 71% of the beat cycle twice. The strongest photometric signal, at 197.560 min, is ascribed to a side-band period. During times of light-curve stability, the photometry modulates at the spin frequency, supporting our WD spin-period identification. Both one-pole and two-pole accretion configurations repeat from one beat cycle to the next with clear and repeatable beat-phase-dependent intensity variations. To explain these, we propose the operation of a magnetic valve at L1. The magnetic valve modulates the mass-transfer rate, as evidenced by a factor of 5 variation in orbital-averaged intensity, over the course of the beat cycle in a repeatable manner. The accretion stream threading distance from the WD is also modulated at the beat period, because of the variation of the WD magnetic field with respect to the stream and because of changes in the mass transfer rate due to the operation of the magnetic valve. Changes in the threading distance result in significant shifts in the position of accreting spots around the beat cycle. As a consequence, only the faintest photometric minima allow for an accurate ephemeris determination. Three regions on the WD appear to receive most of the accretion flow, suggestive of a complex WD magnetic field

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries