Modelling and optimization of the processing of a healthy snack bar made of grape and tomato pomaces

A snack made of 36% by-products of grape and tomato pomaces was developed, also including other ingredients such as oats, chia, quinoa, honey, and peanut butter. The recipe was defined as tasty and healthy by a focus group. The snack was produced by using forced air at three different drying temperatures (50 °C, 60 °C and 70 °C). The Newton, Page, Henderson & Pabis, and Midil-li-Kucuk models fit the drying curves well. The average values for the Newton’s model drying constants were: k50= 2.71x10-1 ± 3x10-3 min-1; k60= 2. 76x10-1 ± 4x10-3 min-1 and k70= 3.91x10-1 ± 8x10-3 min-1; at 50 °C, 60 °C and 70 °C, respectively. The product’s quality was assessed over storage, regarding water activity and texture (hardness, springiness, cohesiveness, chewiness and resilience). The three tested processing temperatures did not influence the final product’s quality differently. Since there are no significant differences between initial and final water activity and texture attributes for any temperature, and they were mainly unaltered over storage, the snack bar was considered stable during this period. This new snack which includes by-products from the food industry reduces food waste and contributes to a circular economy model, simultaneously presenting environmental and economic advantages.info:eu-repo/semantics/publishedVersio

Musculoskeletal pain in family caregivers: Does a therapeutic physical program in primary care work? A randomized controlled trial

Producción CientíficaBackground: Family caregivers play a crucial role in the overall healthcare system and in our society. The elderly population is significantly increasing, which creates a high demand for family caregivers. Few studies have investigated the impact of caregiving on musculoskeletal pain or proposed an active approach for dealing with it. Objectives: To determine and characterize musculoskeletal pain in female family caregivers (FFCs) and assess the effects of adding a therapeutic exercise program to a family caregiver care program (FCCP) on the quality of life, physical conditions, and psychological well-being of FFCs. Methods: A multicenter randomized controlled clinical trial was conducted with 68 FFCs recruited in two public healthcare areas. The intervention and control groups received the same conventional FCCP for 6 h across 4 sessions. The intervention group received an additional 36 sessions of physical therapeutic exercise (PTE) program over 12 weeks. Results: All caregivers reported having pain in particular locations. Lower back pain and neck pain were the locations most frequently cited, with a prevalence of 69.4% and 56.7%, respectively. In total, 80% of participants presented moderate pain intensity. The intervention group showed a significant decrease in the intensity of the pain (p < 0.001), as well as in anxiety, depression, subjective burden perception (p < 0.01), and quality-of-life variables, including MCS (mental component summary) (p < 0.05) and PCS (physical component summary) (p < 0.001). Conclusions: A PTE program improved the musculoskeletal pain of FFCs in a clinically relevant way. The caregivers who improved the most were those who initially presented the most intense pain, had the greatest levels of disability, and had the lowest quality of life.Colegio Profesional de Fisioterapeutas de Castilla y León (CPFCyL) - (grant INV 2019-11

Effects of a family caregiver care programme in musculoskeletal pain and disability in the shoulder-neck region—A randomised clinical trial

Producción CientíficaLife expectancy in Spain has increased and older people need more health care to improve their quality of life. The high demands of the population sometimes collapse health services, making them insufficient to cover their needs, which leads to the development of “non-professional caregivers”. These caregivers have suffered musculoskeletal injuries of the cervical spine and shoulders and should be guided and assessed on ergonomics, biomechanics, or kinesiotherapy. However, there are no interventions to help them care for themselves. This study presents the application of a physical exercise programme to prevent these disorders in women caregivers of dependent patients. It consists of a randomised controlled clinical trial with two groups: both received a family caregiver care programme, and the intervention group also received a physical therapeutic exercise programme for 12 weeks. A total of 62 caregivers completed the study, who were mostly daughters or wives of dependents. Of these, 70.97% presented a “moderate” pain intensity and a cervical disability of 13.72 ± 7.64 points in the NDI questionnaire in the initial evaluation. In the intervention group of caregivers, there was a significant decrease in the pain intensity and a significant increase (p < 0.05) in all cervical joint amplitude movements. Caregivers present a high prevalence of musculoskeletal disorders. The physical exercise programme was effective in reducing the intensity of pain, lumbar disability, and cervical disability of the family caregivers.Colegio Profesional de Fisioterapeutas de Castilla y León (CPFCyL) - (grant INV 2019-11

La imposibilidad del copropietario de adquirir por prescripción adquisitiva los bienes en copropiedad y su influencia en el tráfico de bienes en la ciudad de Huancayo, 2017-2018

El problema de investigación inicia con la formulación de ¿Cómo al no poder el copropietario, adquirir por prescripción adquisitiva los bienes en copropiedad afecta el tráfico jurídico de bienes en la ciudad de Huancayo 2017 -2018?; teniendo como objetivo Determinar cómo al no poder adquirir el copropietario por prescripción adquisitiva los bienes en copropiedad afectan el tráfico jurídico de bienes en la ciudad de Huancayo 2017 -2018; planteando como hipótesis: Al no poder adquirir por prescripción adquisitiva el copropietario, los bienes de copropiedad afecta el tráfico jurídico de bienes, por existir bienes indivisos, igualdad de derechos de participación de copropietarios, por la negligencia del copropietario, y por la imprescriptibilidad de derechos de acción de partición y la, en la ciudad de Huancayo 2017 -2018. La metodología utilizada comprende al método deductivo – inductivo, sistemático, exegético; el tipo de investigación es la básica y jurídico social, el nivel es el explicativo; el diseño es el explicativo causal; la población y muestra comprende de 50 profesionales entre jueces y especialistas legales, el tipo de muestreo es el no probabilístico – intencional; se utilizó como técnica la encuesta, análisis doctrinario. Se obtuvo como resultado que, la prohibición establecida en el artículo 985 del código civil está impidiendo el tráfico jurídico de bienes; y llegando a la conclusión que al existir igualdad de derechos en la copropiedad, al ser los bienes indivisos, y la negligencia del copropietario no poseedor, está afectando los derechos del copropietario poseedor, por encontrarse limitado en el tráfico de bienes por la inseguridad jurídica que genera.Tesi

Carbon nanomaterials with Thymol + Menthol Type V natural deep eutectic solvent: From surface properties to nano-Venturi effect through nanopores

A theoretical study using Density Functional Theory and classical Molecular Dynamics simulations for the study of carbon nanomaterials in archetypical Menthol + Thymol Type V Natural Deep Eutectic Solvent is reported. The nanoscopic structure of the representative nanofluid is analyzed considering confinement, adsorption and solvation effects, as well as consequences on diffusion properties through nano pores. Different types of nanomaterials were considered such as fullerenes, nanotubes, graphene and nanopores. The study of nanoscopic properties allowed to analyze the response of the solvent to the presence of the nanomaterials, taking into account solvent rearrangement and confinement in nanocavities and surfaces. This response shows liquid structure and mobility consequences, with a sort of nano-Venturi effect among them. The reported results provide for the first time a characterization of this type of natural solvents as a sustainable platform for the development of carbon – nanomaterials-based technologies.This work was funded by Junta de Castilla y León (Spain, project NANOCOMP - BU058P20), European Union H2020 Program (H2020-NMBP-TO-IND-2020-twostage-DIAGONAL-GA- 953152) and Ministerio de Ciencia, Innovación y Universidades (Spain, project RTI2018-101987-B-I00). We also acknowledge SCAYLE (Supercomputación Castilla y León, Spain) for providing supercomputing facilities. The statements made herein are solely the responsibility of the authors

Comparative Life Cycle Assessment of Green Sand Casting and Low Pressure Die Casting for the production of self-cleaning AlMg3-TiO2 Metal Matrix Composite

The growth in the use of novel materials, as it is the case of the Metal Matrix Composites (MMCs), is producing a positive impact in production processes, allowing to obtain final products with improved functionalities, such as an increase of the strength-to-weight ratio, or enhancement of the mechanical properties of the material, minimizing as well the environmental impacts and production costs without compromising the required technical properties. To determine and compare the environmental impact of different processes employing these materials, this paper provides a comparative analysis of the Life Cycle Assessment (LCA), under ISO 14040:2006 framework and European ILCD guidelines, of two different manufacturing technologies, Green Sand Casting (GSC) and Low Pressure Die Casting (LPDC), for the particular case of a self-cleaning doorknob, produced by an aluminium alloy reinforced with hard TiO2 nanoparticles, that confers special characteristics to the composite, such as an increase of the hardness value and tensile strength, a high wear resistance, a good chemical stability, and antibacterial properties. The results show a slight difference between both technologies in terms of kg CO2 eq. emitted, with just a 3,16 % variation, where GSC emissions are 13,098 kg, whereas 12,684 kg are released from LPDC. In addition, an economic analysis was performed, showing a 17 % cost reduction in case of LPDC. This study presents for the first time a comparative Life Cycle Assessment of GSC and LPDC, when employing new nanocomposite materials, contributing with novel datasets and meaningful insights to improve the state of the art in the field, serving as well as a support for manufacturers in decision making process involving the use of these technologies.This research has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (Grant Agreement No. 826312) in the context of the LightMe project. It has also received funds from Board of Education of Junta de Castilla y León and the European Social Fund (EDU/1508/2020). The authors want to acknowledge the support of ÖGI (Österreichisches Gießerei-Institut) for the data about processes

The aetiology of paediatric inflammatory vulvovaginitis

5 p.Vulvovaginitis is the most common gynaecological problem in prepubertal girls and clear-cut data on the microbial aetiology of moderate to severe infections are lacking. Many microorganisms have been reported in several studies, but frequently the paediatrician does not know the pathogenic significance of an isolate reported in vaginal specimens of girls with vulvovaginitis. A multicentre study was performed, selecting 74 girls aged 2 to 12 years old with a clinical picture of vulvovaginitis and inflammatory cells on Gram stain. All the specimens were cultured following standard microbiological techniques and the paediatricians completed a questionnaire to highlight risk factors after interviewing the parents or tutors. The data were compared with those obtained in a control group of 11 girls without vulvovaginitis attending a clinic. Streptococcus pyogenesand Haemophilus spp.were isolated in 47 and 12 cases, respectively. Upper respiratory infection in the previous month ( P<0.001) and vulvovaginitis in the previous year ( P<0.05) were identified as significant risk factors. Foreign bodies, sexual abuse, poor hygiene and bad socioeconomic situation were not identified as risk factors for the infection

The direct and indirect effects of COVID‐19 pandemic in a real‐life hematological setting

Background: Clinical outcomes of novel coronavirus 2019 disease (COVID-19) in onco-hematological patients are unknown. When compared to non-immunocompromised patients, onco-hematological patients seem to have higher mortality rates. Aims: We describe the characteristics and outcomes of a consecutive cohort of 24 onco-hematological patients with COVID-19 during the first month of the pandemic. We also describe variations in healthcare resource utilization within our hematology department. Methods and results: Data from patients between the first month of the pandemic were retrospectively collected. Clinical and logistic data were also collected and compared with the average values from the prior 3 months of activity. Prevalence of COVID-19 in our hematological population was 0.4%. Baseline characteristics were as follows: male sex: 83%, lymphoid diseases: 46%, median age: 69 (22-82) years. Median follow-up in survivors was 14 (9-28) days and inpatient mortality rate was 46%. Average time to moderate/severe respiratory insufficiency and death were 3 (1-10) and 10 (3-18) days, respectively. Only 1 out of every 12 patients who developed moderate to severe respiratory insufficiency recovered. Upon univariate analysis, the following factors were associated with higher mortality: age ≥ 70 years (P = .01) and D-dimer ≥900 mcg/L (P = .04). With respect to indirect effects during the COVID-19 pandemic, and when compared with the prior 3 months of activity, inpatient mortality (excluding patients with COVID-19 included in the study) increased by 56%. This was associated with a more frequent use of vasoactive drugs (+300%) and advanced respiratory support (+133%) in the hematology ward. In the outpatient setting, there was a reduction in initial visits (-55%) and chemotherapy sessions (-19%). A significant increase in phone visits was reported (+581%). Conclusion: COVID-19 pandemic is associated with elevated mortality in hematological patients. Negative indirect effects are also evident within this setting

Cruise Summary Report - MEDWAVES survey. MEDiterranean out flow WAter and Vulnerable EcosystemS (MEDWAVES)

The MEDWAVES (MEDiterranean out flow WAter and Vulnerable EcosystemS) cruise targeted areas under the potential influence of the MOW within the Mediterranean and Atlantic realms. These include seamounts where Cold-water corals (CWCs) have been reported but that are still poorly known, and which may act as essential “stepping stones” connecting fauna of seamounts in the Mediterranean with those of the continental shelf of Portugal, the Azores and the Mid-Atlantic Ridge. During MEDWAVES sampling has been conducted in two of the case studies of ATLAS: Case study 7 (Gulf of Cádiz-Strait of Gibraltar-Alboran Sea) and Case study 8 (Azores). The initially targeted areas in the Atlantic were: the Gazul Mud volcano, in the Gulf of Cádiz (GoC) area, included in the case study 7, and the Atlantic seamounts Ormonde (Portuguese shelf) and Formigas (by Azores), both part of the case study 8. In the Mediterranean the targeted areas were The Guadiaro submarine canyon and the Seco de los Olivos (also known as Chella Bank) seamount. Unfortunately it was not possible to sample in Guadiaro due to time constraints originated by adverse meteorological conditions which obligate us to reduce the time at sea focusing only in 4 of the 5 initially planned areas. MEDWAVES was structured in two legs; the first leg took place from the 21st September (departure from Cádiz harbour in Spain) to the 13th October 2016 (arrival in Ponta Delgada, São Miguel, Azores, Portugal took place the 8th of October due to the meteorological conditions that obligated to conclude the first leg earlier as planned). during the Leg 1 sampling was carried out in Gazul, Ormonde and Formigas. The second leg started the 14th October (departure from Ponta Delgada) and finished the 26th October (arrival in Málaga harbour, Spain). MEDWAVES had a total of 30 effective sampling days, being 6 days not operative due to the adverse meteorological conditions experienced during the first leg which forced us to stay in Ponta Delgada from the 08th to the 13th October. During MEDWAVES the daily routine followed a similar scheme, depending of course on the weather and sea conditions. The main activity during the day, starting early in the morning (around 08:00 AM, once the night activities were finished), was the ROV deployment. Generally a single ROV dive of around 8 hours was performed, however in several occasions two dives were carried out in the same day (see General station list, Appendix II). After the ROV (and sometimes between two dives) the Box Corer and/or Van Veen Grab and/or Multicore was deployed. After these activities, during the night CTD-Rosette deployments and MB was conducted. Accordingly to this schema the scientific personnel worked in the day or in the night watch. A total of 215 sampling stations have been covered in MEDWAVES, using the following sampling gears: Multibeam echosounder, CTD-Rosette, LADCP, Box Corer, Van Veen Grab, Multicorer and a Remotely Operated Vehicle (ROV). Table 1 sumamrised the number of sampling stations conducted with each gear in each sampling zone. Additionally MB surveys have been conducted during the transits between area

Discourse Analysis and Terminology in Languages for Specific Purposes

Aquest importantíssim recull conté estudis i reflexions sobre temes rellevants en la recerca sobre LSP: anglès mèdic, el llenguatge de la publicitat i periodístic, telecomunicacions i terminologia informàtica, llenguatge comercial i jurídic... Malgrat que gran part dels treballs aplegats es refereixen a l'anglès, també hi ha que tracten l'alemany, francès i altres llengües. Conté textos en anglès, francés, portuguès i castellà