Design of the psychological intervention programme "Florece" for university students

Objetivo: Diseñar un Programa para aumentar el bienestar psicológico dirigido a jóvenes estudiantes de una Institución de Educación Superior. Metodología: Se desarrolló la investigación desde el paradigma positivista, enfoque cuantitativo de alcance proyectivo, durante la fase descriptiva se reconocieron el diagnóstico del nivel de bienestar psicológico y en la fase proyectiva se postularon las unidades y actividades de intervención que finalmente fueron validadas por jueces expertos. Resultados: el principal hallazgo en el proceso investigativo fue el reconocimiento de modelo de intervención por programas como pertinente para fomentar el bienestar psicológico en población universitaria. Conclusión: como resultado se diseñó un programa para el fortalecimiento del bienestar psicológica de carácter virtual.Objective: To design a programme to increase psychological well-being aimed at young students of a Higher Education Institution. Methodology: The investigation was developed from the positivist paradigm, quantitative approach of projective scope, during the descriptive phase the diagnosis of the level of psychological well-being was recognized and in the projective phase the intervention units and activities were postulated and finally validated by expert judges. Results: the main finding in the research process was the recognition of the intervention model by programs as pertinent to promote psychological well-being in the university population. Conclusion: as a result, a program was designed to strengthen virtual psychological well-being

Clinical Validation of a 3-Dimensional Ultrafast Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences

Objectives: This study sought to clinically validate a novel 3-dimensional (3D) ultrafast cardiac magnetic resonance (CMR) protocol including cine (anatomy and function) and late gadolinium enhancement (LGE), each in a single breath-hold. Background: CMR is the reference tool for cardiac imaging but is time-consuming. Methods: A protocol comprising isotropic 3D cine (Enhanced sensitivity encoding [SENSE] by Static Outer volume Subtraction [ESSOS]) and isotropic 3D LGE sequences was compared with a standard cine+LGE protocol in a prospective study of 107 patients (age 58 ± 11 years; 24% female). Left ventricular (LV) mass, volumes, and LV and right ventricular (RV) ejection fraction (LVEF, RVEF) were assessed by 3D ESSOS and 2D cine CMR. LGE (% LV) was assessed using 3D and 2D sequences. Results: Three-dimensional and LGE acquisitions lasted 24 and 22 s, respectively. Three-dimensional and LGE images were of good quality and allowed quantification in all cases. Mean LVEF by 3D and 2D CMR were 51 ± 12% and 52 ± 12%, respectively, with excellent intermethod agreement (intraclass correlation coefficient [ICC]: 0.96; 95% confidence interval [CI]: 0.94 to 0.97) and insignificant bias. Mean RVEF 3D and 2D CMR were 60.4 ± 5.4% and 59.7 ± 5.2%, respectively, with acceptable intermethod agreement (ICC: 0.73; 95% CI: 0.63 to 0.81) and insignificant bias. Both 2D and 3D LGE showed excellent agreement, and intraobserver and interobserver agreement were excellent for 3D LGE. Conclusions: ESSOS single breath-hold 3D CMR allows accurate assessment of heart anatomy and function. Combining ESSOS with 3D LGE allows complete cardiac examination in less than 1 min of acquisition time. This protocol expands the indication for CMR, reduces costs, and increases patient comfort. (J Am Coll Cardiol Img 2021;14:1742–1754)Funding included Instituto de Salud Carlos III (ISCIII) and the European Regional Development Fund (ERDF) Grants DTS17/00136 to Dr. Ibáñez and PI19/01704 to Dr. Fernandez-Jimenez; Spanish Society of Cardiology Translational Research Grant 2016 to Dr. Ibáñez; European Research Council ERC-CoG 819775-MATRIX to Dr. Ibáñez; Comunidad de Madrid S2017/BMD-3867-RENIM-CM to Drs. Desco and Ibáñez; and Ministerio de Ciencia e Innovación (MICINN) RETOS2019-107332RB-I00 to Dr. Ibáñez. Dr. Fernandez-Jimenez received funding from the European Union Horizon 2020 research and innovation programme under Marie Sklodowska-Curie Hrant Agreement No. 707642. The CNIC is supported by the ISCIII, the MICINN, and the Pro CNIC Foundation. Drs. Fernandez-Jimenez, Nothnagel, Fuster, Ibáñez, and Javier Sánchez-González are inventors of a joint patent (Philips/CNIC) for the new cine imaging method here described and validated/protected under the IP #2014P00960EP. Drs. Nothnagel, Kouwenhoven, Clemence, and Javier Sánchez-González are Philips employees. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose

Strengths of character according to gender in people from Salinas de Guardas: Intervention perspective from the PERMA Model to the solidarity economy

Las fortalezas del carácter son son características relativamente estables que se pueden manifestar a través de comportamientos, pensamientos o sentimientos y son la vía mediante la cual se puede llegar a una virtud tal y como lo plantea el modelo Values in Action (VIA). Objetivo: Determinar las fortalezas de carácter representativas de las personas de Salinas de Guaranda, Ecuador. Materiales y métodos: Estudio cuantitativo descriptivo, trasversal en una muestra de personas de Salinas de Guaranda de 370 personas, 162 hombres y 208 mujeres entre 15 y 65 años de edad. La recolección de la información se realizó mediante el cuestionario VIA de fortalezas, con previa autorización de uso y adaptación cultura, fiabilidad de la prueba en coherencia con la prueba original alfa de 966 Alfa de Cronbach, cuestionario VIA de fortalezas de carácter de 120 ítems. En cuanto al procesamiento de los datos se realizó análisis descriptivos y análisis de diferencias estadísticas significativas con el test no paramétrico de la U de Mann-Whitney en apoyo de SPSS 23. Resultados: Las fortalezas de carácter representativas con la puntuación más alta fue la esperanza, seguida de gratitud y en puntuaciones que le siguen están trabajo en equipo, curiosidad, justicia, honestidad, perseverancia, amabilidad, espiritualidad y ánimo. Conclusiones: las fortalezas halladas en la población ecuatoriana de Salinas de Guardas son predictores de conductas sustentables, además de favorecer la satisfacción con la vida y el compromiso vital. La gratitud es la fortaleza que moviliza acciones de reciprocidad, acciones pro-sociales que presentan diferencias significativas entre mujeres frente a los hombres evaluados en el presente estudio.Strengths of character are relatively stable characteristics that can be manifested through behaviors, thoughts or feelings and are the way through which a virtue can be reached, as proposed by the Values in Action (VIA) model. Objective: To determine the representative strengths of the people of Salinas de Guaranda, Ecuador. Materials and methods: Descriptive, cross-sectional quantitative study in a sample of 370 people from Salinas de Guaranda, 162 men and 208 women, between 15 and 65 years old. The information was collected using the VIA strengths questionnaire, with prior authorization for use and cultural adaptation, reliability of the test in coherence with the original alpha test of 966, Cronbach’s Alpha, VIA questionnaire of character strengths of 120 items. Regarding data processing, descriptive analysis and analysis of significant statistical differences were performed with the non-parametric test of the Mann-Whitney U in support of SPSS 23. Results: The representative character strengths with the highest score were hope, followed by gratitude and in scores that follow are teamwork, curiosity, justice, honesty, perseverance, kindness, spirituality and encouragement. Conclusions: the strengths found in the Ecuadorian population of Salinas de Guardas are predictors of sustainable behaviors, as well as favoring life satisfaction and vital commitment. Gratitude is the strength that mobilizes actions of reciprocity, pro-social actions which presents significant differences between women compared to the men evaluated in this study

Evidence on port-locking with heparin versus saline in patients with cancer not receiving chemotherapy: A randomized clinical trial

Objective: To assess the safety and efficacy of port-locking with heparin every 2 months vs. every 4 months and vs. saline solution every 2 months in patients with cancer not receiving active chemotherapy. The hypothesis stated that locking with heparin at four-month intervals and saline at two-month intervals would not increment > 10% of port obstructions. Methods: Multicentre, phase IV parallel, post-test control group study took place at the two chemotherapy units of oncology hospitals. Included patients with cancer with ports that completed the chemotherapy treatment but still having port maintenance care or blood samples taken up to four months. A sample of 126 patients with cancer in three arms was needed to detect a maximum difference of 10% for bioequivalence on the locking methods. Consecutive cases non-probabilistic sampling and randomized to one of the three groups; group A: received heparin 60 IU/mL every two months (control) vs. group B heparin every four months and vs. saline every two months in group C. Primary variables were the type of locking regimen, port obstruction, and absence of blood return, port-related infection, or venous thrombosis during the study period. Clinical and sociodemographic variables were also collected. Results: A total of 143 patients were randomly assigned; group A, 47 patients with heparin every 2 months, group B, 51 patients with heparin 4 months, and group C, 45 patients with saline every 2 months. All participants presented an adequate blood return and no obstructions, until the month of the 10th, when one participant in the group A receiving was withdrawn due to an absence of blood flow ( P 1/4 0.587). Conclusions: Port locks with heparin every 4 months or saline every 2 months did not show differences in safety maintenance, infection, or thrombosis compared to heparin every 2 months

Rapid hemodilution induced by desmopressin after erythropoietin administration in humans

We have shown that treatment with desmopressin has a very effective hemodilution effect in healthy humans. These results led us to suggest the possible role of desmopressin to mask blood doping in sports. Based on our results, the World Anti-Doping Agency included the desmopressin in the 2011 List of Prohibited Substances and Methods. On this occasion, the aim of our study was to test the desmopressin-induced hemodilution after rHuEpo administration in humans. This was an intra-subject, crossover study in which five physically active males acted as their own controls. A basal blood sample was taken on their first visit to the laboratory. The next day, the subjects began the treatment. They received a subcutaneous rHuEpo injection three times/week for a two-week period. On the second visit to the laboratory, seventeen days later, a blood sample was taken. Thereafter, the subjects received an oral dose of 4.3 μg/kg of desmopressin and were instructed to ingest 1.5 liters of mineral water during the following fifteen minutes. Three hours after the water ingestion a second blood sample was obtained. The samples were analyzed for hematocrit (HCT), hemoglobin (Hb), reticulocytes (Ret%) and OFF Hr-Score. We found significantly higher HCT, Hb and Ret% levels after rHuEpo administration. Administration of desmopressin significantly decreased the HCT and Hb values but we did not find significant changes in Ret%. The values of the OFF Hr-Score also decreased after treatment with desmopressin. Desmopressin has a very effective hemodilution effect after rHuEpo administration and significantly modifies the hematological values measured by the anti-doping authorities to detect blood doping. We consider that these results reinforce the conclusions reported in our first study and confirm that desmopressin is a very effective masking agent for blood doping.This work was supported by grants SAF2008-00270; SAF2009-08334; BFU2007-65803/BFI; from the Spanish Ministry of Education and Science (MEC); PROMETEO/2010/074 from the Consellería de Educación de la Generalitat Valenciana. ISCIII2006-RED13-027 from the “Red Temática de investigación cooperativa en envejecimiento y fragilidad (RETICEF)”, EU Funded COSTB35 and DPS2008-06968 from Spanish Ministry of Innovation and Science. This study has been co-financed by FEDER funds from the European Union

Propuesta Estratégica de Mejora en la Implementación de los Estándares Mínimos del Sistema de Gestión de la Seguridad y Salud en el Trabajo (SG-SST) en la compañía de Seguridad Azimut Caribabare Ltda para el primero y segundo semestre del año 2020

Sistema de gestión, accidente de trabajo, ciclo phva, consecuencia, Indicadores de matriz.Resumen En el presente trabajo analizaremos el sistema de SG-SST de la empresa COMPAÑÍA DE SEGURIDAD AZIMUT CARIBABARE LTDA, en donde analizaremos por medio de la tabla de valores los estándares mínimos del sistema de gestión de la seguridad y salud en el trabajo (SG-SST), identificando las debilidades e implementado un plan de acción de mejora que contribuyan a la planeación, organización, ejecución, y evaluación de las intervenciones sobre las condiciones de salud (Medicina Preventiva y del Trabajo), y de trabajo (Higiene y Seguridad Industrial), tendientes a mejorar la salud individual y colectiva de los trabajadores en su labor y que deben ser desarrolladas en sus sitios de trabajo en forma integral e interdisciplinaria. Asumiendo la responsabilidad de diseñar e implementar un sistema de gestión de la seguridad y salud en el trabajo (SG-SST), que tiene como propósito la acción conjunta entre la corporación y los trabajadores, en la aplicación de las medidas de Seguridad y Salud en el Trabajo (SST) a través del mejoramiento continuo de las condiciones y el medio ambiente laboral, y el control eficaz de los peligros y riesgos en el lugar de trabajo. Palabras claves: Sistema de gestión, accidente de trabajo, ciclo phva, consecuencia, Indicadores de matriz.Abstract In this paper we will analyze the SG-SST system of the company COMPAÑÍA DE SEGURIDAD AZIMUT CARIBABARE LTDA, where we will analyze through the table of values the minimum standards of the occupational health and safety management system (SG-SST ), identifying weaknesses and implementing an improvement action plan that contributes to the planning, organization, execution, and evaluation of interventions on health conditions (Preventive and Work Medicine), and work (Industrial Hygiene and Safety) , aimed at improving the individual and collective health of workers in their work and that must be developed in their work sites in an integral and interdisciplinary way. Assuming the responsibility of designing and implementing a system of occupational safety and health management (SG-SST), whose purpose is joint action between the corporation and the workers, in the application of Health and Safety measures in Work (OSH) through continuous improvement of working conditions and environment, and effective control of hazards and risks in the workplace. Keywords: Management system, work accident, phva cycle, consequence, Matrix indicators

Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice

Skeletal muscle adapts to different exercise training modalities with age; however, the impact of both variables at the systemic and tissue levels is not fully understood. Here, adult and old C57BL/6 male mice were assigned to one of three groups: sedentary, daily high-intensity intermittent training (HIIT), or moderate intensity continuous training (MICT) for 4 weeks, compatible with the older group’s exercise capacity. Improvements in body composition, fasting blood glucose, and muscle strength were mostly observed in the MICT old group, while effects of HIIT training in adult and old animals was less clear. Skeletal muscle exhibited structural and functional adaptations to exercise training, as revealed by electron microscopy, OXPHOS assays, respirometry, and muscle protein biomarkers. Transcriptomics analysis of gastrocnemius muscle combined with liver and serum metabolomics unveiled an age-dependent metabolic remodeling in response to exercise training. These results support a tailored exercise prescription approach aimed at improving health and ameliorating age-associated loss of muscle strength and function in the elderly.This work was supported by funding from the Intramural Research Program of the National Institute on Aging/NIH. Work in JMV laboratory was supported by the Spanish Ministerio de Economía y Competitividad (MINECO) grant BFU2015-64630-R, Ministerio de Ciencia, Innovación y Universidades (MICIU) grant RTI2018-100695-B-I00, Spanish Junta de Andalucía grants P18-RT-4264, 1263735-R and BIO-276, the FEDER Funding Program from the European Union, and Universidad de Córdoba. MCR was supported by a FPU fellowship from the Spanish Ministerio de Educación, Cultura y Deporte (reference FPU14/06308). SRL held a FPI predoctoral contract funded by MINECO (reference BES-2016-078229).Peer reviewe

Temas Socio-Jurídicos. Volumen 19 No. 40 Junio de 2001

Las opiniones contenidas en los artículos de esta revista no vinculan a la institución, sino que son de exclusiva responsabilidad de los autores, dentro de los principios democráticos de la cátedra libre y la libertad de expresión consagrados en el artículo 3o. del estatuto general de la corporación universidad autónoma de Bucaramanga - UNAB. El material de esta publicación puede ser reproducido sin autorización, siempre que se mencione su procedencia y el Centro de Investigaciones Socio-Jurídicas de la UNAB, reciba un ejemplar de la publicación.The opinions contained in the articles of this magazine do not bind the institution, but are the sole responsibility of the authors, within the democratic principles of the free chair and freedom of expression enshrined in article 3. of the general statute of the autonomous university corporation of Bucaramanga - UNAB. The material in this publication may be reproduced without authorization, as long as its source is mentioned and the Socio-Legal Research Center of UNAB receives a copy of the publication