Coaching High School English Teachers in Guided Reading for Struggling Readers

Although small-group guided reading is traditionally an elementary school instructional practice, this study details how high school English teachers perceived its implementation in high school classrooms. As part of a larger, multiyear research project, this 2-year study examined a dual-level coaching professional learning program that included two school district literacy coaches, eight provincial literacy facilitators, and 21 high school teachers. Teachers were coached in the implementation of guided reading and small-group instruction to support students in Grades 9–10 who were struggling with reading. Qualitative methods were used to gather data including observations of the professional learning meetings and teachers’ instruction; interviews with literacy coaches, professional literacy facilitators, and teachers; and artifact collection. Data were analyzed using the qualitative software program NVivo. The findings suggest that teacher coaching, modeling, co-planning, discussion, and reflection enhanced teachers’ abilities to support students in their use of metacognitive skills and comprehension strategies during guided reading. Teachers noted some insightful instructional considerations for implementation of elementary instructional practices in their high school English classrooms. Overall, these results have practical implications for teachers seeking to help struggling high school readers

The Use of Social Media by Dental Students for Communication and Learning: Two Viewpoints

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153760/1/jddjde019072.pd

Tecnologias para tratamento de dejeto de suínos.

Projeto/Plano de Ação: 03.11.09.012

Avaliação de acessos de Aegilops tauschii quanto ao recrescimento das raízes em solução nutritiva após exposição ao alumínio.

Área: Melhoramento, Aptidão Industrial e Sementes

Kidney transplant nephrotic syndrome: Relationship between allograft histopathology and natural course

Kidney transplant nephrotic syndrome: Relationship between allograft histopathology and natural course. We analyzed clinical and pathologic data from 36 recipients of 38 renal allografts who developed nephrotic syndrome following transplantation. Three groups were identified on the basis of histologic changes in the graft, and each group had a distinct clinical course. Nine grafts (23.7%) had recurrent glomerulonephritis (GN) (5 membrano-proliferative, 4 focal glomerulosclerosis) and developed nephrotic syndrome at 5.1 months (mean) posttransplant. Renal function deteriorated rapidly, with a 2-year graft survival of 29.7%. Four grafts (10.5%) with de novo GN (3 epimembranous, 1 minimal change) developed nephrotic syndrome at 32 months post-transplant, and all functioned for more than 3 years. Twenty-five grafts (65.8%) had allograft glomerulopathy with the onset of nephrotic syndrome at 9.1 months posttransplant and a 2-year graft survival of 66.6%. The differences in duration of graft function between grafts with allograft glomerulopathy and recurrent GN (P < 0.01) and in graft survival rates at 2 years among the three groups (P < 0.05) are statistically significant. This analysis indicates that allograft glomerulopathy is the most common cause of kidney transplant nephrotic syndrome. Membranopro-liferative GN and focal glomerulosclerosis may recur soon after transplantation and rapidly progress to renal failure in marked contrast to grafts with either de novo epimembranous nephropathy or minimal glomerular change, lesions that are compatible with prolonged graft function.Syndrome néphrotique du rein transplanté: Relations entre l'histopathologies de l'allogreffe et l'évolution. Nous avons analysé les dossiers cliniques et anatomo-pathologiques de 36 receveurs de 38 allogreffes qui ont développé un syndrome néphrotique après transplantation. Trois groupes ont été identifiés sur la base des modifications histologiques de la greffe et chaque groupe a eu une évolution distincte. Neuf greffes (23,7%) ont eu une récidive de glomérulonéphrite (GN) (5 membrano-prolifératives, 4 gloméruloscléroses focales) et ont développé un syndrome néphrotique 5,1 mois (moyenne) après la transplantation. La fonction rénale s'est détériorée rapidement, avec une survie de la greffe à 2 ans de 29,7%. Quatre greffes (10,5%) atteintes de GN nouvelle (3 extra-membraneuses, 1 à modifications minimes) ont développé un syndrome néphrotique 32 mois après la transplantation et ont toutes fonctionné plus de 3 ans. Vingt cinq greffes (65,8%) ont eu une glomérulopathie de greffe avec l'installation d'un syndrome néphrotique à 9,1 mois après la transplantation et une survie de la greffe à 2 ans de 66,6%. Les différences de durée du fonctionnement de la greffe selon l'atteinte par une récidive de GN ou une glomérulopathie de greffe (P < 0,01) et dans la survie des greffes à 2 ans dans les trois groupes (P < 0,05) sont statistiquement significatives. Cette analyse indique que la glomérulonéphrite de la greffe est la cause la plus répandue de syndrome néphrotique du rein transplanté. La GN membrano-proliférative et la glomérulosclérose focale peuvent récidiver précocement après la transplantation et progresser rapidement vers l'insuffisance rénale à la différence des greffes atteintes de néphropathie extramembraneuse ou de modifications minimes, lésions compatibles avec une fonction prolongée de la greffe

Genome wide association scan for chronic periodontitis implicates novel locus

Background: There is evidence for a genetic contribution to chronic periodontitis. In this study, we conducted a genome wide association study among 866 participants of the University of Pittsburgh Dental Registry and DNA Repository, whose periodontal diagnosis ranged from healthy (N = 767) to severe chronic periodontitis (N = 99).Methods: Genotypingi of over half-million single nucleotide polymorphisms was determined. Analyses were done twice, first in the complete dataset of all ethnicities, and second including only samples defined as self-reported Whites. From the top 100 results, twenty single nucleotide polymorphisms had consistent results in both analyses (borderline p-values ranging from 1E-05 to 1E-6) and were selected to be tested in two independent datasets derived from 1,460 individuals from Porto Alegre, and 359 from Rio de Janeiro, Brazil. Meta-analyses of the Single nucleotide polymorphisms showing a trend for association in the independent dataset were performed.Results: The rs1477403 marker located on 16q22.3 showed suggestive association in the discovery phase and in the Porto Alegre dataset (p = 0.05). The meta-analysis suggested the less common allele decreases the risk of chronic periodontitis.Conclusions: Our data offer a clear hypothesis to be independently tested regarding the contribution of the 16q22.3 locus to chronic periodontitis. © 2014 Feng et al.; licensee BioMed Central Ltd

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ‘accidental cell death’ (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. ‘Regulated cell death’ (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to classify it into a few subtypes, which often (but not always) exhibit stereotyped morphologic features. Nonetheless, efficiently inhibiting the processes that are commonly thought to cause RCD, such as the activation of executioner caspases in the course of apoptosis, does not exert true cytoprotective effects in the mammalian system, but simply alters the kinetics of cellular demise as it shifts its morphologic and biochemical correlates. Conversely, bona fide cytoprotection can be achieved by inhibiting the transduction of lethal signals in the early phases of the process, when adaptive responses are still operational. Thus, the mechanisms that truly execute RCD may be less understood, less inhibitable and perhaps more homogeneous than previously thought. Here, the Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death

Evolução do padrão de aleitamento materno

OBJECTIVE: To follow the evolution of the breastfeeding practice among women in a childbirth clinic and evaluate the actions for its promotion. METHODS: Two cohorts of children born in an school hospital of Porto Alegre, Brazil, in different periods of time were compared regarding the prevalence of breastfeeding during the first six months of life, and the percentage of early cessation of breastfeeding. Both were prospective studies, including 202 children in the cohort of 1987, and 187 children in the cohort of 1994. All participants were healthy children, with birth weight of 2500g or more, were being breastfed and their parents were living in the same house. The 1987 study children were followed up through mail, and the 1994 study ones by home visits. RESULTS: Survival analysis showed similar frequencies of breastfeeding in the two cohorts. The prevalence of exclusive breastfeeding, although for a short period in both groups, was higher in the population studied in 1994, especially among children whose mothers were better educated. There was no rate difference of early cessation of breastfeeding between the two cohorts (36% for the 1987 cohort and 39% for the 1994 cohort). CONCLUSIONS: The results revealed a certain degree of apathy in regard of the promotion of breastfeeding during the studied period, giving support to actions to promote breastfeeding, especially among poor families.OBJETIVO: Acompanhar a evolução da prática do aleitamento materno na clientela de maternidade e avaliar as ações para sua promoção. MÉTODOS: Foram comparadas duas coortes de crianças nascidas em épocas diferentes em hospital de Porto Alegre, RS, quanto às prevalências do aleitamento materno nos primeiros seis meses de vida das crianças bem como as taxas de interrupção precoce da amamentação. Os dois estudos foram prospectivos, envolvendo 202 crianças na coorte de 1987 e 187 na de 1994, todas saudáveis, com peso de nascimento igual ou superior a 2.500 g, tendo iniciado o aleitamento materno e cujos pais morassem juntos. O acompanhamento foi realizado através de correspondência, no estudo de 1987, e de visitas domiciliares, no estudo de 1994. RESULTADOS: As curvas de sobrevida do aleitamento materno revelaram que o percentual de crianças amamentadas ao longo dos primeiros seis meses foi semelhante nas duas coortes. A prevalência do aleitamento materno exclusivo, apesar de baixa nos dois grupos, foi superior na população de 1994, especialmente entre as crianças cujas mães tinham maior escolaridade. Não houve diferença no índice de interrupção precoce entre as duas coortes (36% na coorte de 1987 e 39% na de 1994). CONCLUSÕES: Os resultados apontam para uma apatia do serviço com relação à promoção do aleitamento materno no período estudado, justificando plenamente o investimento na promoção da amamentação, especialmente nas famílias menos privilegiadas