919 research outputs found

    eta' meson under partial restoration of chiral symmetry in nuclear medium

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    We shed light upon the eta' mass in nuclear matter in the context of partial restoration of chiral symmetry, pointing out that the U_{A}(1) anomaly effects causes the eta'-eta mass difference necessarily through the chiral symmetry breaking. As a consequence, it is expected that the eta' mass is reduced by order of 100 MeV in nuclear matter where partial restoration of chiral symmetry takes place. The discussion given here is based on Ref. [1].Comment: 3 pages, 2 figures. Contribution to Meson201

    The Environmental Influence on the Evolution of Local Galaxies

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    The results of an Halpha photometric survey of 30 dwarf galaxies of various morphologies in the Centaurus A and Sculptor groups are presented. Of these 30, emission was detected in 13: eight are of late-type, two are early-type and three are of mixed-morphology. The typical flux detection limit of 2e-16 erg s-1 cm-2, translates into a Star Formation Rate (SFR) detection limit of 4e-6 M_sol yr-1 . In the light of these results, the morphology-density relation is reexamined: It is shown that, despite a number of unaccounted parameters, there are significant correlations between the factors determining the morphological type of a galaxy and its environment. Dwarf galaxies in high density regions have lower current SFR and lower neutral gas content than their low density counterparts, confirming earlier results from the Local Group and other denser environments. The effect of environment is also seen in the timescale formed from the ratio of blue luminosity to current SFR - dwarfs in higher density environments have larger values, indicating relatively higher past average SFR. The influence of environment extends very far and no dwarfs from our sample can be identified as 'field' objects.Comment: 23 pages, 9 figures, accepted in A

    Schwannoma of the vagus nerve, a rare middle mediastinal neurogenic tumor: case report

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    Schwannoma originating from the vagus nerve within the mediastinum is a rare, usually benign tumor. A 44-year old male was presented with chest pain. Chest radiography, CT scan and MRI showed a well circumscribed mass, 5 × 4 cm located in the aortopulmonary window. The mass was found at surgery to be in close proximity with the aortic arch and the left pulmonary hilum, alongside the left vagus nerve. The encapsulated tumor was completely resected through a left thoracotomy incision and it was found to be a benign schwannoma in pathology. The patient is free of recurrence 6 years after surgery

    Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice

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    Tuberculosis, caused by infection with Mycobacterium tuberculosis (Mtb), kills over 1.6 million people each year despite availability of antibiotics. The increase in drug resistant Mtb strains is a major public health emergency and host-directed therapy as adjunct to antibiotic treatment has gained increased interest. Cyclooxygenase inhibitors (COXi) are frequently used drugs to alleviate tuberculosis related symptoms. Mouse studies of acute intravenous Mtb infection have suggested a potential benefit of COXi for host-directed therapy. Here we show that COXi treatment (ibuprofen and celecoxib) is detrimental to Mtb control in different mouse models of respiratory infection. This effect links to impairments of the Type-1 helper (Th1) T-cell response as CD4 T-cells in COXi-treated animals have significantly decreased Th1 differentiation, reduced IFNγ expression and decreased protective capacity upon adoptive transfer. If confirmed in clinical trials, these findings could have major impact on global health and question the use of COXi for host-directed therapy.publishedVersio

    Three-Nucleon Force Effects in Nucleon Induced Deuteron Breakup: Predictions of Current Models (I)

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    An extensive study of three-nucleon force effects in the entire phase space of the nucleon-deuteron breakup process, for energies from above the deuteron breakup threshold up to 200 MeV, has been performed. 3N Faddeev equations have been solved rigorously using the modern high precision nucleon-nucleon potentials AV18, CD Bonn, Nijm I, II and Nijm 93, and also adding 3N forces. We compare predictions for cross sections and various polarization observables when NN forces are used alone or when the two pion-exchange Tucson-Melbourne 3NF was combined with each of them. In addition AV18 was combined with the Urbana IX 3NF and CD Bonn with the TM' 3NF, which is a modified version of the TM 3NF, more consistent with chiral symmetry. Large but generally model dependent 3NF effects have been found in certain breakup configurations, especially at the higher energies, both for cross sections and spin observables. These results demonstrate the usefulness of the kinematically complete breakup reaction in testing the proper structure of 3N forces.Comment: 42 pages, 20 ps figures, 2 gif figure

    Physiology of invasion: Cane toads are constrained by thermal effects on physiological mechanisms that support locomotor performance

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    Understanding the mechanisms that constrain the invasiveness of introduced animals is essential for managing invasions and for predicting their limits. In most vertebrate species, the capacity for invasion relies upon the physiological systems that support locomotion, and oxygen transport and metabolism may become limiting as environmental temperatures increase as predicted by the oxygen limitation hypothesis. Here we test the oxygen limitation hypothesis and propose the alternative hypothesis that within-individual plasticity will compensate for thermal variation. We show that during exercise in the invasive cane toad (Rhinella marina) oxygen transport by the cardiovascular system was maximised in warm-acclimated toads at high (30 degrees C) temperatures, and that oxygen content of arterial blood was not affected by temperature. Resting oxygen consumption remained stable across a 10 degrees C temperature range (20-30 degrees C) when toads were allowed to acclimate, so that there was no increase in resting oxygen demand that could lead to a decrease in aerobic scope at high temperatures. Additionally, temperature acclimation had no effect on arterial-venous differences in oxygen partial pressures. Toads relied more on glycolytic ATP production at low temperatures to support locomotor activity. Mitochondrial capacities (citrate synthase and cytochrome c oxidase activities) were greatest at warmer temperatures. Interestingly, the metabolic cost of exercise increased at low temperatures. In contradiction to predictions by the oxygen limitation hypothesis, aerobic performance was not limited by high temperatures. On the contrary, the relatively slow advance of cane toads to cooler climates can be explained by the constraints of low temperatures on the physiological systems supporting locomotion. It is likely that human-induced global warming will facilitate invasions of environments that are currently too cool to support cane toads
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