1,329 research outputs found

    A GEOLOGIA/GEOMORFOLOGIA COSTEIRA NOS LIVROS DIDÁTICOS DE GEOGRAFIA: POR UMA PRÁTICA PEDAGÓGICA CONTEXTUALIZADA

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    Os livros didáticos continuam a ser a principal referência na sala de aula para alunos e professores das escolas públicas e privadas do país, embora muitas vezes utilizado de forma variada: em alguns momentos estimula a reflexão sobre o espaço geográfico e em outros trabalha com a Geografia de modo tradicional e não reflexivo. O objetivo deste trabalho é analisar como a geologia/geomorfologia costeira é abordada nos livros didáticos de Geografia, bem como refletir a prática pedagógica docente

    El valor de la templanza en las relaciones familiares (En los escritos de Pedro-Juan Viladrich Bataller)

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    La familia “es una comunidad de personas, para las cuales el propio modo de existir y vivir juntos” exige la vivencia intensa y cotidiana del amor “bueno”, que es el “principio interior”, la “fuerza permanente” de las relaciones intrafamiliares, que son únicas y exclusivas de la “comunidad doméstica”, pues brotan de la “conyugalidad” y la “consanguinidad”. Los familiares para vivir bien estas relaciones amorosas cuentan con un conjunto de valores que les son propios e intrínsecos, entre cuales se encuentra el valor familiar de la templanza, que propicia un ambiente hogareño de armonía, estabilidad y unidad. Enseñando, adquiriendo y viviendo este valor los esposos, padres, hijos y hermanos avivan y renuevan la dinámica del “amor familiar incondicional y desnudo”: darse a sí mismo y abrirse para recibir al otro con todo lo que es y tiene.The family “is a community of persons, whose own way of existing and living together” requires a daily intense experience of “good” love, that is the inner principle, the permanent power of intra-family relationships, that are unique and exclusive of the “domestic community”, as they arise from the “conjugality” and the “consanguinity”. To live well these relationships of love the relatives have a group of values that are exclusive and inherent, among which, the temperance is one of the family values that fosters a homey atmosphere of harmony, stability, and unity. Teaching, acquiring and living this value, husbands and wives, fathers and mothers, sons and daughters, and brothers and sisters intensify and renew the dynamics of the “transparent and unconditional family love”; self-giving to oneself and opening to the other accepting what he is and he has

    Didactic demonstration of the interaction between electric currents

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    We present the first crucial experiment by Ampère that shows the interaction of two metallic wires carrying steady currents. We discuss its importance in the history of physics. We also present a modern reproduction of the procedures and observations of Ampère with low cost materials.Apresentamos a primeira experiência crucial de Ampère mostrando a interação entre dois fios metálicos conduzindo correntes elétricas. Discutimos sua importância na história da física. Descrevemos uma reprodução moderna dos procedimentos e observações de Ampère com materiais de baixo custo.60561

    Seasonal variation of zooplankton and environmental conditions along a transect in the Gulf of Cádiz

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    This study presents seasonal variation in the zooplankton composition of the Gulf of Cádiz was studied between 2001 and 2012. Samples were collected three times per year, in the spring, summer and autumn at three stations situated along a transect perpendicular to the coast. The total zooplankton abundance during the summer was higher than in the spring and autumn. Zooplankton community is characterized by a seasonal cycle mirroring similar cycles in the physical environment. Differences in community composition were also found along the transect, particularly between the coastal station, under the influence of the Guadalquivir River, and the outer station, characterized by oceanic conditions. This study is the first description of the seasonal and spatial variation of this marine component of the Gulf of Cádi

    Monitoring Of Bcr-abl Levels In Chronic Myeloid Leukemia Patients Treated With Imatinib In The Chronic Phase - The Importance Of A Major Molecular Response

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    Background: Real time PCR has become the most common technique to monitor BCR-ABL transcript levels of patients treated with kinase inhibitors. The aim of this study was to evaluate BCR-ABL levels of chronic myeloid leukemia patients treated with imatinib in the chronic phase and correlate the response to therapy and event-free survival. Methods: BCR-ABL levels were measured in peripheral blood cell samples using Real time PCR at diagnosis and then every 3 months after starting therapy with imatinib. Major molecular response was defined as a three-log reduction from the standardized baseline value. Major molecular response values were adjusted to international scale using a conversion factor of 1.19. The results are reported as a BCR-ABL/ABL ratio (%). Results: Hematological, major cytogenetic and complete cytogenetic responses were achieved by 57 (95%), 45 (75%) and 38 (63%) patients, respectively. Twenty-four out of sixty patients achieved a major molecular response (40%) in a median time of 8.5 months. Overall survival and event free survival were higher for patients with (100%) versus patients without (77%) a complete cytogenetic response (p-value = 0.01) at 48 months. Patients with complete cytogenetic response and major molecular response had a higher event free survival compared to patients with complete cytogenetic response but without major molecular response (p-value = 0.007). Conclusion: In conclusion, the prognostic impact of achieving complete cytogenetic response and a major molecular response and also the importance of molecular monitoring in the follow-up of chronic myeloid leukemia patients were demonstrated.333211215Melo, J.V., The molecular biology of chronic myeloid leukaemia (1996) Leukemia, 10 (5), pp. 751-756Wang, L., Pearson, K., Pillitteri, L., Ferguson, J.E., Clark, R.E., Serial monitoring of BCR-ABL by peripheral blood real-time polymerase chain reaction predicts the marrow cytogenetic response to imatinib mesylate in chronic myeloid leukaemia (2002) Br J Haematol, 118 (3), pp. 771-777Muller, M.C., Gattermann, N., Lahaye, T., Deininger, M.W., Berndt, A., Fruehauf, S., Dynamics of BCR-ABL mRNA expression in firstline therapy of chronic myelogenous leukemia patients with imatinib or interferon alpha/ara-C (2003) Leukemia, 17 (12), pp. 2392-2400Branford, S., Hughes, T.P., Rudzki, Z., Monitoring chronic myeloid leukaemia therapy by real-time quantitative PCR in blood is a reliable alternative to bone marrow cytogenetics (1999) Br J Haematol, 107 (3), pp. 587-599Radich, J.P., Gooley, T., Bryant, E., Chauncey, T., Clift, R., Beppu, L., The significance of bcr-abl molecular detection in chronic myeloid leukemia patients late, 18 months or more after transplantation (2001) Blood, 98 (6), pp. 1701-1707Hughes, T.P., Kaeda, J., Branford, S., Rudzki, Z., Hochhaus, A., Hensley, M.L., Frequency of major molecular responses to imatinib or interferon-alpha plus cytarabine in newly diagnosed chronic myeloid leukemia (2003) N Engl J Med, 349 (15), pp. 1423-1432Press, R.D., Love, Z., Tronnes, A.A., Yang, R., Tran, T., Mongoue- tchokote, S., BCR-ABL mRNA levels at and after the time of a complete cytogenetic response predict the duration of CCR in imatinib mesylate-treated patients with CML (2006) Blood, 107 (11), pp. 4250-4256Cortes, J., Talpaz, M., O'Brien, S., Jones, D., Luthra, R., Shan, J., Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate (2005) Clin Cancer Res, 11 (9), pp. 3425-3432Iacobucci, I., Saglio, G., Rosti, G., Testoni, N., Pane, F., Amabile, M., Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients (2006) Clin Cancer Res, 12 (10), pp. 3037-3042Baccarani, M., Saglio, G., Goldman, J., Hochhaus, A., Simonsson, B., Appelbaum, F., Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet (2006) Blood, 108 (6), pp. 1809-1820Hughes, T., Deininger, M., Hochhaus, A., Branford, S., Radich, J., Kaeda, J., Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results (2006) Blood, 108 (1), pp. 28-37Branford, S., Cross, N.C., Hochhaus, A., Radich, J., Saglio, G., Kaeda, J., Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia (2006) Leukemia, 20 (11), pp. 1925-1930Cortes, J., Baccarani, M., Fea, G., (2008) A Phase III, Randomized, Openlabel Study of 400 Mg Versus 800 Mg of Imatinib Mesylate (IM) in Patients With Newly Diagnosed, Previously Untreated Chronic Myeloid Leukemia in Chronic Phase (CML-CP), Using Molecular Endpoints: One Year Results of TOPS (Tyrosine Kinase Inhibitor Optimization and Selectivity) Study, , 50th ASH Annual Meeting and Exposition Online program and Abstracts. San Francisco, CABranford, S., Fletcher, L., Cross, N.C., Muller, M.C., Hochhaus, A., Kim, D.W., Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials (2008) Blood, 112 (8), pp. 3330-3338O'Brien, S.G., Guilhot, F., Larson, R.A., Gathmann, I., Baccarani, M., Cervantes, F., Imatinib compared with interferon and lowdose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia (2003) N Engl J Med, 348 (11), pp. 994-1004Marin, D., Milojkovic, D., Olavarria, E., Khorashad, J.S., de Lavallade, H., Reid, A.G., European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor (2008) Blood, 112 (12), pp. 4437-444

    Multiple-photon Peak Generation Near The 10 M Range In Quantum Dot Infrared Photodetectors

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    We present results from simulations of the photocurrent observed in recently fabricated InAs quantum dot infrared photodetectors that respond with strong resonance peaks in the ∼ 10 m wavelength range. The results are in good agreement with experimental data generated earlier. Multiphoton scattering of electrons localized in the quantum dots are not only in accordance with the observed patterns, but are also necessary to explain the photocurrent spectrum obtained in the calculations. © 2011 American Institute of Physics.1096Martyniuk, P., Rogalski, A., (2008) Prog. Quantum Electron., 32, p. 89. , For a recent review, see, 10.1016/j.pquantelec.2008.07.001Chakrabarti, S., Stiff-Roberts, A.D., Su, X.H., Bhattacharya, P., Ariyawansa, G., Perera, A.G.U., High-performance mid-infrared quantum dot infrared photodetectors (2005) Journal of Physics D: Applied Physics, 38 (13), pp. 2135-2141. , DOI 10.1088/0022-3727/38/13/009, PII S002237270592069XLim, H., Zhang, W., Tsao, S., Sills, T., Szafraniec, J., Mi, K., Movaghar, B., Razeghi, M., Quantum dot infrared photodetectors: Comparison of experiment and theory (2005) Physical Review B - Condensed Matter and Materials Physics, 72 (8), p. 085332. , http://oai.aps.org/oai/?verb=ListRecords&metadataPrefix= oai_apsmeta_2&set=journal:PRB:72, DOI 10.1103/PhysRevB.72.085332Razeghi, M., Lim, H., Tsao, S., Szafraniec, J., Zhang, W., Mi, K., Movaghar, B., Transport and photodetection in self-assembled semiconductor quantum dots (2005) Nanotechnology, 16 (2), pp. 219-229. , DOI 10.1088/0957-4484/16/2/007Pal, D., Towe, E., (2006) Appl. Phys. Lett., 88, p. 153109. , 10.1063/1.2193466Bhattacharya, P., Su, X.H., Chakrabarti, S., Ariyawansa, G., Perera, A.G.U., Characteristics of a tunneling quantum-dot infrared photodetector operating at room temperature (2005) Applied Physics Letters, 86 (19), pp. 1-3. , DOI 10.1063/1.1923766, 191106Dupont, E., Corkum, P., Liu, H.C., Wilson, P.H., Buchanan, M., Wasilewski, Z.R., (1994) Appl. Phys. Lett., 65, p. 1560. , 10.1063/1.113004Maier, T., Schneider, H., Walther, M., Koidl, P., Liu, H.C., (2004) Appl. Phys. Lett., 84, p. 5162. , 10.1063/1.1763978Jiang, J., Fu, Y., Li, N., Chen, X.S., Zhen, H.L., Lu, W., Wang, M.K., Li, Y.G., (2004) Appl. Phys. Lett., 85, p. 3614. , 10.1063/1.1781732Aivaliotis, P., Zibik, E.A., Wilson, L.R., Cockburn, J.W., Hopkinson, M., Vinh, N.Q., (2008) Appl. Phys. Lett., 92, p. 023501. , 10.1063/1.2833691Sirtori, C., Capasso, F., Sivco, D.L., Cho, A.Y., (1992) Appl. Phys. Lett., 60, p. 2678. , 10.1063/1.106893Souza, P.L., Lopes, A.J., Gebhard, T., Unterrainer, K., Pires, M.P., Villas-Boas, J.M., Vieira, G.S., Studart, N., Quantum dot structures grown on Al containing quaternary material for infrared photodetection beyond 10 μm (2007) Applied Physics Letters, 90 (17), p. 173510. , DOI 10.1063/1.2733603Gebhard, T., Alvarenga, D., Souza, P.L., Guimares, P.S.S., Unterrainer, K., Pires, M.P., Vieira, G.S., Villas-Boas, J.M., (2008) Applied Phys. Lett., 93, p. 052103. , 10.1063/1.2965804Pryor, C.E., Pistol, M.-E., Band-edge diagrams for strained III-V semiconductor quantum wells, wires, and dots (2005) Physical Review B - Condensed Matter and Materials Physics, 72 (20), pp. 1-11. , http://oai.aps.org/oai/?verb=ListRecords&metadataPrefix= oai_apsmeta_2&set=journal:PRB:72, DOI 10.1103/PhysRevB.72.205311, 205311Degani, M.H., Maialle, M.Z., (2010) J. Comput. Theor. Nanosci., 7, p. 454. , 10.1166/jctn.2010.1380Feit, M.D., Fleck Jr., J.A., Steiger, A., (1982) J. Comput. Phys., 47, p. 412. , 10.1016/0021-9991(82)90091-2Degani, M.H., (1991) Appl. Phys. Lett., 59, p. 57(2002) Phys. Rev. B, 66, p. 23306. , 10.1063/1.105521Maialle, M.Z., Degani, M.H., Madureira, J.R., Farinas, P.F., (2009) J. Appl. Phys., 106, p. 123703. , 10.1063/1.3270263Fano, U., Cooper, J.W., (1968) Rev. Mod. Phys., 40, p. 441. , 10.1103/RevModPhys.40.441Tsolakidis, A., Snchez-Portal, D., Martin, R.M., (2002) Phys. Rev. B, 66, p. 235416. , 10.1103/PhysRevB.66.23541

    Transfer-matrix scaling from disorder-averaged correlation lengths for diluted Ising systems

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    A transfer matrix scaling technique is developed for randomly diluted systems, and applied to the site-diluted Ising model on a square lattice in two dimensions. For each allowed disorder configuration between two adjacent columns, the contribution of the respective transfer matrix to the decay of correlations is considered only as far as the ratio of its two largest eigenvalues, allowing an economical calculation of a configuration-averaged correlation length. Standard phenomenological-renormalisation procedures are then used to analyse aspects of the phase boundary which are difficult to assess accurately by alternative methods. For magnetic site concentration pp close to pcp_c, the extent of exponential behaviour of the Tc×pT_c \times p curve is clearly seen for over two decades of variation of ppcp - p_c. Close to the pure-system limit, the exactly-known reduced slope is reproduced to a very good approximation, though with non-monotonic convergence. The averaged correlation lengths are inserted into the exponent-amplitude relationship predicted by conformal invariance to hold at criticality. The resulting exponent η\eta remains near the pure value (1/4) for all intermediate concentrations until it crosses over to the percolation value at the threshold.Comment: RevTeX 3, 11 pages +5 figures, uuencoded, to appear in Phys. Rev. B (1994), PUC/RJ preprin

    Electron localization : band-by-band decomposition, and application to oxides

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    Using a plane wave pseudopotential approach to density functional theory we investigate the electron localization length in various oxides. For this purpose, we first set up a theory of the band-by-band decomposition of this quantity, more complex than the decomposition of the spontaneous polarization (a related concept), because of the interband coupling. We show its interpretation in terms of Wannier functions and clarify the effect of the pseudopotential approximation. We treat the case of different oxides: BaO, α\alpha-PbO, BaTiO3_3 and PbTiO3_3. We also investigate the variation of the localization tensor during the ferroelectric phase transitions of BaTiO3_3 as well as its relationship with the Born effective charges
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