7 research outputs found

    Inaccurate forecasting of a randomized controlled trial

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    Published online: 22 November 2023We report the results of a forecasting experiment about a randomized controlled trial that was conducted in the field. The experiment asks Ph.D. students, faculty, and policy practitioners to forecast (1) compliance rates for the RCT and (2) treatment effects of the intervention. The forecasting experiment randomizes the order of questions about compliance and treatment effects and the provision of information that a pilot experiment had been conducted which produced null results. Forecasters were excessively optimistic about treatment effects and unresponsive to item order as well as to information about a pilot. Those who declare themselves expert in the area relevant to the intervention are particularly resistant to new information that the treatment is ineffective. We interpret our results as suggesting that we should exercise caution when undertaking expert forecasting, since experts may have unrealistic expectations and may be inflexible in altering these even when provided new information

    Brazilian First Names and Gender Ratios

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    This dataset contains a list of ~74,000 Brazilian first names and how often each each name is used for a male or female candidates in the 2000, 2004, 2008, and 2012 municipal elections in Brazil. Thus it effectively works as a tool to classify the gender of any Brazilian (and perhaps Portuguese) name.The original data can be found on the Brazilian Electoral Tribunal's website here. In total, there are 1,653,604 candidates in municipal elections from 2000-2012 and 1,652,685 had gender reported in the officially provided data. I simply take the first characters in the reported names that preceded a space and count the reported genders associated with that name. This yielded 74,650 unique first names which make up this dataset. There are errors in this data set, but if you are matching from a well-formed list of names than this should work fairly well as a prediction of the gender of the names in a different list with minimal manipulation of the original dataset

    2018 Pakistan General Election Candidate Scrutiny Forms

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    This repository hosts cleaned candidate scrutiny forms released by the Election Commission of Pakistan for prospective candidates for Pakistan's 2018 national and provincial assembly elections. The scrutiny forms consist of data released on tax payments from the Federal Board of Revenue (FBR), corruption cases from the the National Accountability Bureau (NAB), and oustanding loans from the State Bank of Pakistan (SBP). The final output after cleaning is also included as pk_candidate_scrutiny_data_2018.csv, or in wide format (collapsing three reported tax-year rows per candidate into a single row) as pk_candidate_scrutiny_data_2018_wide.csv

    Aspiration of Conjugated Bile Acids Predicts Adverse Lung Transplant Outcomes and Correlates with Airway Lipid and Cytokine Dysregulation.

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    Introduction: Duodeno-gastroesophageal reflux aspiration is associated with chronic lung allograft dysfunction (CLAD). Reflux aspirate can contain bile acids (BA), functional molecules in the gastro-intestinal tract with emulsifying properties. We sought to determine and quantify the various BA species in airways of the lung transplant recipients to better understand the various effects of aspirated BA that contribute to post-transplantation outcomes. Methods: Bronchial washings (BW) were prospectively collected from lung transplant recipients and subsequently assayed by liquid chromatography-mass spectrometry for 13 BA and 25 lipid families. Patients were monitored for CLAD, rejection, inflammation and airway infections. Results: Detectable BA were present in 45/50 patients (90%) at 3 months after transplant. Elevated BA and predominance of conjugated species were independent predictors of CLAD (hazard ratio 7.9; 95% confidence interval 2.7-23.6; p < 0.001 and 7.3; 2.4-22; p < 0.001, respectively) and mortality (hazard ratio 4.4; 1.5-12.7; p = 0.007 and 4.8; 1.4-15.8; p = 0.01, respectively). High BA associated with increased positive bacterial cultures (60% vs 25%, p = 0.02). Primary conjugated species independently correlated with the rate of bacterial cultures during the first-year post-transplant (Beta coefficient: 0.77; 0.28-1.26; p = 0.003) and changes in airway lipidome and cytokines. Conclusions: Higher BA levels and predominance of conjugated BA are independent predictors of chronic lung allograft dysfunction, mortality and bacterial infections. Primary conjugated BA are related to distinct changes in airway lipidome and inflammatory cytokines. This elucidates novel evidence into the mechanism following BA aspiration and proposes novel markers for prediction of adverse post-transplant outcomes
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