Theory Review of CP Violations in B Decays at Hadron Colliders

CP violations in B meson decays at hadron colliders are reviewed. In particular I examine: $B^0-\bar{B^0}$ mixing and oscillations within Standard Model and the Cabibbo-Kobayashi-Maskawa picture for CP violations; $B^0$ decays into CP eigenstates and the measurements of the angles in the unitarity triangle; finally I consider a class of charged $B$ decays that allow to avoid uncertainties arising from the computation of hadronic matrix elements.Comment: 16 pages, 4 figures (not included) available upon request, LaTex, BARI-TH/93-13

Adipocyte proteome and secretome influence inflammatory and hormone pathways in glioma

Gliomas represent the most common primary malignant brain tumors in adults, with an extremely poor prognosis. Among several risk factors, lifestyle was also recently identified as a major risk factor for the development of primary glioma. In the present study, we explore the relationship between obesity and glioma in a cellular model. Thus, we have study the influence of adipocytes secretome on glioma cell line GL261. Using the 3T3-L1 adipocyte cell line, and its conditioned medium (adipokines-enriched medium), we showed that adipocyte-released factors relate with glioma angiogenic, growth, hormones and metabolic behavior by MALDI-TOF-MS and proteomic array analysis. In a first view, STI1, hnRNPs and PGK1 are under expressed on CGl. Similarly, both carbonic anhydrase and aldose reductase are even suppressed in glioma cells that grown under adipokines-enriched environment. Contrariwise, RFC1, KIF5C, ANXA2, N-RAP and RACK1 are overexpressed in GL261 cell the in the presence of the adipokines-enriched medium. We further identified the factors that are released by adipocyte cells, and revealed that several pro-inflammatory and angiogenic factors, such as IL-6, IL-11, LIF, PAI-1, TNF-α, endocan, HGF, VEGF IGF-I, were secreted to the medium into a high extent, whereas TIMP-1 and SerpinE1 were under expressed on CGl. This study discloses an interesting in vitro model for the study of glioma biology under a "obesity" environment, that can be explored for the understanding of cancer cells biology, for the search of biomarkers, prognostic markers and therapeutic approaches.info:eu-repo/semantics/publishedVersio

Dosagem e aplicação de concreto pesado de densidade 4.000 e 4.500 kg/m3

Heavyweight concretes are an attractive alternative when heavyweight elements need to fill reduced spaces, because they present high densities and are able to take different forms according to the container where they are casted. The intended application for the heavyweight concrete referred to in this work is a power converter, which is a floating system that generates power through the waves of the sea. The design of this converter considers the use of elements of high mass at both ends of a metallic oval structure. Therefore, a heavyweight concrete with density of 4,000 and 4,500 kg/m3 was developed. For heavyweight concrete production with densities as high as the ones needed, it is necessary to use artificial aggregates of steel grit or corundum. Natural heavyweight aggregates such as hematite, magnetite or barite allow achieving maximum densities around 3,800 kg/m3, being unsuitable for the required application. For this reason, grit coarse aggregate 6-8 mm was used and a portion of the sand was replaced by a corundum fine aggregate 0.5-1.5 mm, being these materials out of the standard applications. In addition to the density requirements, consistency of the fresh concrete is also important as the use of heavyweight aggregates, whose density differs from the density of the mortar or paste, may lead to segregation of the mix. Due to the particularities of the concrete, the mix-design process was oriented to the specific application and quantitative and qualitative requirements were evaluated such as concepts related to the availability of the component materials, accessibility to the production area and casting. Therefore, the aim of this work is to present the considerations made during the mix-design process as well as the characterization of the heavyweight concretes produced, which showed results in agreement with the pre-established requirements