PACIAE 2.0: An updated parton and hadron cascade model (program) for the relativistic nuclear collisions

We have updated the parton and hadron cascade model PACIAE for the relativistic nuclear collisions, from based on JETSET 6.4 and PYTHIA 5.7 to based on PYTHIA 6.4, and renamed as PACIAE 2.0. The main physics concerning the stages of the parton initiation, parton rescattering, hadronization, and hadron rescattering were discussed. The structures of the programs were briefly explained. In addition, some calculated examples were compared with the experimental data. It turns out that this model (program) works well.Comment: 23 pages, 7 figure

Enhancement of singly and multiply strangeness in p-Pb and Pb-Pb collisions at 158A GeV/c

The idea that the reduction of the strange quark suppression in string fragmentation leads to the enhancement of strange particle yield in nucleus-nucleus collisions is applied to study the singly and multiply strange particle production in p-Pb and Pb-Pb collisions at 158A GeV/c. In this mechanism the strange quark suppression factor is related to the effective string tension, which increases in turn with the increase of the energy, of the centrality and of the mass of colliding system. The WA97 observation that the strange particle enhancement increases with the increasing of centrality and of strange quark content in multiply strange particles in Pb-Pb collisions with respect to p-Pb collisions was accounted reasonably.Comment: 8 pages, 3 PostScript figures, in Latex form. submitted to PR

Charged particle elliptic flow in p+p collisions at LHC energies in a transport model PACIAE

The parton and hadron cascade model PACIAE based on PYTHIA was used to investigate the charged particle elliptic flow in minimum bias pp collisions at the LHC energies. The strings were distributed randomly in the transverse ellipsoid of the pp collision system with major axis of $R$ (proton radius) and minor axis of $R(1-\xi)$ before parton rescattering. The charged particle elliptic flow as a function of the random number $\xi$ and transverse momentum $p_T$ were investigated. The calculated $v_2/\epsilon$ as a function of reaction energy increases monotonously with increasing reaction energy up to $\sqrt{s}\sim$7 TeV and then turns to saturation. With the parton-parton cross section enlarges three times in parton rescattering, the rapidity integrated charged particle elliptic flow may reach 0.025 at $p_T \sim$2 GeV/c in the minimum bias pp collisions at $\sqrt{s}$=7 TeV.Comment: 7 pages, 4 figure

The Effect of Dynamical Parton Recombination on Event-by-Event Observables

Within a dynamical quark recombination model we explore various proposed event-by-event observables sensitive to the microscopic structure of the QCD-matter created at RHIC energies. Charge fluctuations, charge transfer fluctuations and baryon-strangeness correlations are computed from a sample of central Au+Au events at the highest RHIC energy available ($\sqrt{s_{NN}}$=200 GeV). We find that for all explored observables, the calculations yield the values predicted for a quark-gluon plasma only at early times of the evolution, whereas the final state approaches the values expected for a hadronic gas. We argue that the recombination-like hadronization process itself is responsible for the disappearance of the predicted deconfinement signatures. This might explain why no fluctuation signatures for the transition between quark and hadronic matter was ever observed in the experimental data up to now. However, it might also be interpreted as a clear indication for a recombination like hadronization process at RHIC.Comment: 5 page

ABJM Dibaryon Spectroscopy

We extend the proposal for a detailed map between wrapped D-branes in Anti-de Sitter space and baryon-like operators in the associated dual conformal field theory provided in hep-th/0202150 to the recently formulated AdS_4 \times CP^3/ABJM correspondence. In this example, the role of the dibaryon operator of the 3-dimensional CFT is played by a D4-brane wrapping a CP^2 \subset CP^3. This topologically stable D-brane in the AdS_4 \times CP^3 is nothing but one-half of the maximal giant graviton on CP^3.Comment: 26 page

Elderly Patients Undergone Hematopoietic Stem Cell Transplantation: Body Composition and Engraftment

Univ Fed Sao Paulo, Endocrinol, Sao Paulo, BrazilHosp Israelita Albert Einstein, Oncol & Hematol, Sao Paulo, BrazilHosp Israelita Albert Einstein, Sao Paulo, BrazilHosp Israelita Albert Einstein, Dept Hematol & Oncol, Sao Paulo, BrazilHosp Israelita Albert Einstein, BMT, Sao Paulo, BrazilUniv Fed Sao Paulo, Endocrinol, Sao Paulo, BrazilWeb of Scienc

Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer.

Cardiovascular gene therapy is a novel approach to the treatment of diseases such as congestive heart failure (CHF). Gene transfer to the heart would allow for the replacement of defective or missing cellular proteins that may improve cardiac performance. Our laboratory has been focusing on the feasibility of restoring beta-adrenergic signaling deficiencies that are a characteristic of chronic CHF. We have now studied isolated ventricular myocytes from rabbits that have been chronically paced to produce hemodynamic failure. We document molecular beta-adrenergic signaling defects including down-regulation of myocardial beta-adrenergic receptors (beta-ARs), functional beta-AR uncoupling, and an up-regulation of the beta-AR kinase (betaARK1). Adenoviral-mediated gene transfer of the human beta2-AR or an inhibitor of betaARK1 to these failing myocytes led to the restoration of beta-AR signaling. These results demonstrate that defects present in this critical myocardial signaling pathway can be corrected in vitro using genetic modification and raise the possibility of novel inotropic therapies for CHF including the inhibition of betaARK1 activity in the heart

Fluctuations of conserved charges at finite temperature from lattice QCD

We present the full results of the Wuppertal-Budapest lattice QCD collaboration on flavor diagonal and non-diagonal quark number susceptibilities with 2+1 staggered quark flavors, in a temperature range between 125 and 400 MeV. The light and strange quark masses are set to their physical values. Lattices with Nt=6, 8, 10, 12, 16 are used. We perform a continuum extrapolation of all observables under study. A Symanzik improved gauge and a stout-link improved staggered fermion action is utilized. All results are compared to the Hadron Resonance Gas model predictions: good agreement is found in the temperature region below the transition.Comment: 13 pages, 8 figures in Jhep styl

An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome

BACKGROUND: While the genome sequences for a variety of organisms are now available, the precise number of the genes encoded is still a matter of debate. For the human genome several stringent annotation approaches have resulted in the same number of potential genes, but a careful comparison revealed only limited overlap. This indicates that only the combination of different computational prediction methods and experimental evaluation of such in silico data will provide more complete genome annotations. In order to get a more complete gene content of the Drosophila melanogaster genome, we based our new D. melanogaster whole-transcriptome microarray, the Heidelberg FlyArray, on the combination of the Berkeley Drosophila Genome Project (BDGP) annotation and a novel ab initio gene prediction of lower stringency using the Fgenesh software. RESULTS: Here we provide evidence for the transcription of approximately 2,600 additional genes predicted by Fgenesh. Validation of the developmental profiling data by RT-PCR and in situ hybridization indicates a lower limit of 2,000 novel annotations, thus substantially raising the number of genes that make a fly. CONCLUSIONS: The successful design and application of this novel Drosophila microarray on the basis of our integrated in silico/wet biology approach confirms our expectation that in silico approaches alone will always tend to be incomplete. The identification of at least 2,000 novel genes highlights the importance of gathering experimental evidence to discover all genes within a genome. Moreover, as such an approach is independent of homology criteria, it will allow the discovery of novel genes unrelated to known protein families or those that have not been strictly conserved between species

Drop Traffic in Microfluidic Ladder Networks with Fore-Aft Structural Asymmetry

We investigate the dynamics of pairs of drops in microfluidic ladder networks with slanted bypasses, which break the fore-aft structural symmetry. Our analytical results indicate that unlike symmetric ladder networks, structural asymmetry introduced by a single slanted bypass can be used to modulate the relative drop spacing, enabling them to contract, synchronize, expand, or even flip at the ladder exit. Our experiments confirm all these behaviors predicted by theory. Numerical analysis further shows that while ladder networks containing several identical bypasses are limited to nearly linear transformation of input delay between drops, mixed combination of bypasses can cause significant non-linear transformation enabling coding and decoding of input delays.Comment: 4 pages, 5 figure