Interaction pressure tensor on high-order lattice Boltzmann models for nonideal fluids

In this work we address the application of pseudopotentials directly on high-order lattice Boltzmann models. We derive a general expression for the pressure tensor on high-order lattices considering all nonideal interactions, including intra- and intermolecular interactions, following the discrete lattice theory introduced by X. Shan [Phys. Rev. E 77, 066702 (2008)]. From the derived expression, a generalized continuum approximation, truncated at fourth-order isotropy, is obtained that is readily applicable to high-order lattices. With this, we demonstrate that high-order lattice models with pseudopotentials can satisfy thermodynamic consistency. The derived generalized expression and continuum approximation are validated for the case of a flat interface and compared against the standard definition available from the literature. The generalized expression is also shown to accurately reproduce the Laplace experiment for a variety of high-order lattice structures. This work sets the preliminary steps towards the application of high-order lattice models for simulating nonideal fluid mixtures

Formulación y caracterización de nanocápsulas con un antioxidante natural para su aplicación cutánea.

La aplicación de las nanoparticulas poliméricas en el área dermatológica ha adquirido una gran relevancia debido a que pueden liberar activos para que tengan un efecto local o sistémico. El objetivo del presente estudio fue desarrollar y optimizar una formulación de nanocápsulas poliméricas (NC) cargadas con un agente antioxidante natural (carvacrol, CRV) para su potencial aplicación local en la piel. Se obtuvo una formulación de NC biodegradables con CRV que presentaron un tamañopromedio de 180 nm con un IP de 0.083, un potencial Ç= -17.8 mVy un porcentaje de encapsulación del SI %. Por microscopia electrónica de barrido se observa que las poblaciones de NC-CRV eran esféricas y homogéneas. La formulación fue estable por al menos 16 semanas. Además, la tecnica de nanoprecipitación resultó ser un buen método de preparación, ya que, se logro obtener una eficiencia de encapsulaci6nmayor al 90 %. Finalmente, se concluyó que las caracterlsticas y propiedades de la formulación de NCCRV son las adecuadas para que sea usada como sistema acaITea.dor de CRV con una potencial aplicación para prevenir el cáncer de piel causado por la sobre exposición al sol

30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data

Background: There is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts. Materials and methods: This analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien–Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups. Results: In total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07). Conclusions: This global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts. © 2021, The Author(s)